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    US Genome Editing Engineering Market

    ID: MRFR/HC/20201-HCR
    128 Pages
    Rahul Gotadki
    September 2025

    United States Genome Editing Engineering Market Research Report Information By Technology (Mega nucleases, Cas9, TALENs/MegaTALs, ZFN, Others), By Delivery Method (Ex-vivo, In-vivo) By Mode (Contract, In-house), By End-use (Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, Contract Research Organizations), By Application (Genetic Engineering, Clinical Applications) – United States Market Forecast Till 2032

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    Table of Contents

    US Genome Editing Engineering Market Summary

    The United States Genome Editing Engineering Market is projected to grow from 15.75 USD Billion in 2024 to 45.23 USD Billion by 2035.

    Key Market Trends & Highlights

    United States Genome Editing Engineering Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate of 10.07 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 45.23 USD Billion, indicating robust growth potential.
    • The market is currently valued at 15.75 USD Billion in 2024, reflecting a strong foundation for future expansion.
    • Growing adoption of genome editing technologies due to increasing demand for precision medicine is a major market driver.

    Market Size & Forecast

    2024 Market Size 15.75 (USD Billion)
    2035 Market Size 45.23 (USD Billion)
    CAGR (2025 - 2035) 10.07%

    Major Players

    Apple Inc (US), Microsoft Corp (US), Amazon.com Inc (US), Alphabet Inc (US), Berkshire Hathaway Inc (US), Tesla Inc (US), Meta Platforms Inc (US), Johnson & Johnson (US), Visa Inc (US), Procter & Gamble Co (US)

    US Genome Editing Engineering Market Trends

      • Rising demand for synthetic genes is driving the market growth

    The United States market's growth has mostly been fueled by rising demand for synthetic genes and rising use of CRISPR genome editing technology across a range of biotechnology industries. Rising government financing, a rise in the output of genetically modified crops, and an increase in the number of genomics projects are also expected to contribute to the market CAGR growth. CRISPR-based diagnostic techniques that have aided in COVID-19 diagnosis are another factor driving the growth. In March 2021, for instance, a team of researchers from Nanyang Technological University developed the VaNGuard (Variant Nucleotide Guard) diagnostic test in the United States.

    The diagnostics sector will employ CRISPR genome editing technology more frequently as a result of this test's capacity to detect mutant strains of SARS-CoV-2.

    Furthermore, the capacity of the gene-editing technology market to turn a profit is significantly influenced by ongoing technological advancements. In April 2021, for instance, researchers at Harvard's Wyss Institute for Biologically Inspired Engineering developed Retron Library Recombine ring (RLR). Editing rates increased because millions of genetic tests could be conducted simultaneously thanks to this new gene-editing technology. With more government backing and financing for scientific research and development, the United States commanded the biggest market share for genome editing technologies.

    It is also expected that the presence of significant players like Editas Pharmaceuticals, Thermo Fisher Scientific, and CRISPR Therapeutics, as well as rising investment in genomic research, will drive market expansion in this region Additionally, a methodology for using the CRISPR-based Specific High Sensitivity Enzymatic Reporter Unlocking (SHERLOCK) technology to identify COVID-19 has been released by researchers at the Broad Institute of MIT and Harvard. This new method detects the COVID-19 target sequences by using artificial COVID-19 virus RNA fragments. These sequences can be found in the region of 20–200 aM.

    Therefore, the market is expected to grow as a result of research and educational institutions' continued development of new CRISPR editing tools.

    The United States genome editing engineering market is poised for transformative growth, driven by advancements in CRISPR technology and increasing applications in agriculture and medicine.

    U.S. Department of Agriculture

    US Genome Editing Engineering Market Drivers

    Chart: Market Growth Projections

    The Global United States Genome Editing Engineering Market Industry is projected to experience substantial growth over the next decade. The market is expected to reach 15.75 USD Billion in 2024 and is anticipated to grow to 45.23 USD Billion by 2035. This growth trajectory indicates a compound annual growth rate of 10.07% from 2025 to 2035, reflecting the increasing adoption of genome editing technologies across various sectors, including agriculture, healthcare, and biotechnology.

    Advancements in CRISPR Technology

    The Global United States Genome Editing Engineering Market Industry is experiencing rapid advancements in CRISPR technology, which is revolutionizing genetic engineering. CRISPR-Cas9, a prominent tool, allows for precise modifications in DNA, enabling researchers to target specific genes with unprecedented accuracy. This innovation has led to breakthroughs in agriculture, medicine, and biotechnology, fostering a surge in research and development activities. As a result, the market is projected to reach 15.75 USD Billion in 2024, reflecting the growing adoption of CRISPR technology across various sectors. The potential applications in gene therapy and crop improvement further underscore the importance of these advancements.

    Regulatory Support and Frameworks

    The Global United States Genome Editing Engineering Market Industry benefits from evolving regulatory support and frameworks that facilitate the safe application of genome editing technologies. Regulatory bodies are increasingly recognizing the potential benefits of gene editing in agriculture and medicine, leading to the establishment of guidelines that promote innovation while ensuring safety. This supportive environment encourages investment and research, as companies can navigate the regulatory landscape with greater clarity. As the market continues to mature, the establishment of robust regulatory frameworks is likely to enhance public trust and acceptance, further driving market growth and innovation in the coming years.

    Rising Demand for Precision Medicine

    The demand for precision medicine is a significant driver of the Global United States Genome Editing Engineering Market Industry. As healthcare shifts towards personalized treatment approaches, genome editing technologies play a pivotal role in developing targeted therapies. These innovations allow for the customization of treatments based on individual genetic profiles, improving patient outcomes and reducing adverse effects. The market is poised for substantial growth, with a projected compound annual growth rate of 10.07% from 2025 to 2035. This trend reflects a broader shift in healthcare towards more effective and tailored solutions, positioning genome editing as a cornerstone of future medical advancements.

    Increasing Investment in Biotechnology

    Investment in biotechnology is a critical driver for the Global United States Genome Editing Engineering Market Industry. With a growing recognition of the potential of genome editing, venture capital and government funding are increasingly directed towards biotech firms specializing in genetic engineering. This influx of capital supports research initiatives and accelerates the development of innovative solutions. The market is expected to expand significantly, with projections indicating a growth to 45.23 USD Billion by 2035. Such financial backing not only enhances the capabilities of existing companies but also encourages new entrants, fostering a competitive landscape that drives further advancements in genome editing technologies.

    Market Segment Insights

    United States Genome Editing Engineering Technology Insights

    United States Genome Editing Engineering Delivery Method Insights

    United States Genome Editing Engineering Mode Insights

    United States Genome Editing Engineering End-use Insights

    United States Genome Editing Engineering Application Insights

    United States Genome Editing Engineering Country Insights

    Market expansion is fueled by ongoing developments in genome editing technologies, such as CRISPR-Cas9, TALENs, and zinc finger nucleases, which the United States enhances gene editing procedures' accuracy, effectiveness, and user-friendliness. Growing public awareness of genome editing's potential applications in agriculture, healthcare, and other fields encourages acceptance and implementation of these technologies, which in turn fuels demand in the market. The United States As per the deal, CRISPR Therapeutics will provide its genome editing knowledge, while Capsida will offer its adeno-associated virus (AAV) delivery technology.

    With the accomplishment of the Human Genome Project (HGP), around 7,000 new genetic disorders affecting humans have been identified. Although gene treatments based on ex vivo gene editing, such as CAR-T, have had a substantial impact. Moreover, in the United States, the majority of patients with hereditary illnesses need in vivo therapies.

    Get more detailed insights about United States Genome Editing Engineering Market Research Report —Forecast till 2032

    Regional Insights

    Key Players and Competitive Insights

    Leading market players are putting a lot of money into R&D to increase the range of products they sell, which will encourage further growth in the United States Genome Editing Engineering sector. Additionally, market players are engaging in a range of calculated actions to increase their presence, with important market developments including releases of new products, contracts, acquisitions and mergers, increased investments, and cooperation with other enterprises. To grow and endure in a market that is becoming more and more competitive, the United States Genome Editing Engineering industry must provide reasonably priced goods.

    Major players in the United States Genome Editing Engineering market are making investments in R&D operations in an effort to boost market demand, including Intellia Therapeutics, Inc., Caribou Biosciences, Inc., Cellectis S.A., AstraZeneca, Takara Bio USA, Horizon Discovery Group plc, Integrated DNA Technologies, Inc., Egenesis Inc.

    Key Companies in the US Genome Editing Engineering Market market include

    Industry Developments

    January 2022: Pfizer, a global pharmaceutical and biotechnology company with headquarters in the United States, and Beam Therapeutics, a Massachusetts-based company that was first to create CRISPR editing tools, have agreed to a $300 million, four-year contract.

    June 2021: The biotechnology firm Regeneron Pharmaceuticals, with its headquarters located in New York, and Cambridge-based Intellia Therapeutics, which develops biopharmaceuticals, have jointly disclosed a novel therapy that specifically targets the faulty gene responsible for transthyretin amyloidosis.

    Future Outlook

    US Genome Editing Engineering Market Future Outlook

    The United States Genome Editing Engineering Market is projected to grow at a 10.07% CAGR from 2024 to 2035, driven by advancements in CRISPR technology, increasing investment in biotechnology, and rising demand for precision medicine.

    New opportunities lie in:

    • Develop targeted gene therapies for rare genetic disorders to capture niche markets.
    • Invest in CRISPR-based agricultural solutions to enhance crop resilience and yield.
    • Create partnerships with academic institutions for innovative research and development initiatives.

    By 2035, the market is expected to be a pivotal force in biotechnology, significantly impacting healthcare and agriculture.

    Market Segmentation

    United States Genome Editing Engineering Mode Outlook

    • Contract
    • In-house

    United States Genome Editing Engineering End-use Outlook

    • Biotechnology & Pharmaceutical Companies
    • Academic & Government Research Institutes
    • Contract Research Organizations

    United States Genome Editing Engineering Technology Outlook

    • Meganucleases
    • Cas9
    • TALENs/MegaTALs
    • ZFN
    • Others

    United States Genome Editing Engineering Application Outlook

    • Genetic Engineering
    • Clinical Applications

    United States Genome Editing Engineering Delivery Method Outlook

    • Ex-vivo
    • In-vivo

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 USD 3.12 Billion
    Market Size 2024 USD 3.7 Billion
    Market Size 2032 USD 13.69 Billion
    Compound Annual Growth Rate (CAGR) 15.63% (2023-2032)
    Base Year 2022
    Market Forecast Period 2023-2032
    Historical Data 2018-2022
    Market Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Technology, delivery method, application, mode, end-use
    Countries Covered United States
    Key Companies Profiled Intellia Therapeutics, Inc., Caribou Biosciences, Inc., Cellectis S.A., AstraZeneca, Takara Bio USA, Horizon Discovery Group plc, Integrated DNA Technologies, Inc., Egenesis Inc.
    Key Market Opportunities ·         Extending use of CRISPR genome editing technology across a range of scientific domains ·         Rising demand for synthetic genes
    Key Market Dynamics ·         Rising demand for synthetic genes and rising use of CRISPR genome ·         Technology for genome editing across a range of biotechnology domains

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What size is the market for United States Genome Editing Engineering?

    The size of the United States Genome Editing Engineering market was estimated at USD 3.12 billion in 2023.

    How quickly is the United States Genome Editing Engineering market expanding?

    It is anticipated that the market would expand at a compound annual growth rate (CAGR) of 18.70% from 2023 to 2032.

    Who are the leading companies in the United States Genome Editing Engineering industry?

    The key players in the market are Intellia Therapeutics, Inc., Caribou Biosciences, Inc., Cellectis S.A., AstraZeneca, Takara Bio USA, Horizon Discovery Group plc, Integrated DNA Technologies, Inc., Egenesis Inc.

    Which Mode dominated the market for United States Genome Editing Engineering?

    The Contract dominated the market in 2022.

    Which Delivery Method in the United States Genome Editing Engineering market has the biggest market share?

    The Ex-vivo category had the largest share of the market.

    1. EXECUTIVE SUMMARY
    2. MARKET INTRODUCTION
      1. Definition
      2. Scope of the Study
        1. Research Objective
        2. Assumptions
        3. Limitations
    3. RESEARCH METHODOLOGY
      1. Overview
      2. Data Mining
      3. Secondary Research
      4. Primary Research
        1. Primary Interviews and Information Gathering Process
        2. Breakdown of Primary Respondents
      5. Forecasting Model
      6. Market Size Estimation
        1. Bottom-Up Approach
        2. Top-Down Approach
      7. Data Triangulation
      8. Validation
    4. MARKET DYNAMICS
      1. Overview
      2. Drivers
      3. Restraints
      4. Opportunities
    5. MARKET FACTOR ANALYSIS
      1. Value Chain Analysis
      2. Porter’s Five Forces Analysis
        1. Bargaining Power of Suppliers
        2. Bargaining Power of Buyers
        3. Threat of New Entrants
        4. Threat of Substitutes
        5. Intensity of Rivalry
      3. COVID-19 Impact Analysis 
        1. Market Impact Analysis
        2. Regional Impact
        3. Opportunity and Threat Analysis
    6. UNITED STATES GENOME EDITING ENGINEERING, BY TECHNOLOGY
      1. Overview
      2. Meganucleases
      3. Cas9
      4. TALENs/MegaTALs
      5. ZFN
      6. Others
    7. UNITED STATES GENOME EDITING ENGINEERING, BY DELIVERY METHOD
      1. Overview
      2. Ex-vivo
      3. In-vivo
    8. UNITED STATES GENOME EDITING ENGINEERING, BY MODE
      1. Overview
      2. Contract
      3. In-house
    9. UNITED STATES GENOME EDITING ENGINEERING, BY END-USE
      1. Overview 
      2. Biotechnology & Pharmaceutical Companies
      3. Academic & Government Research Institutes
      4. Contract Research Organizations
    10. UNITED STATES GENOME EDITING ENGINEERING, BY APPLICATION
      1. Overview 
      2. Genetic Engineering
      3.   Clinical Applications
    11. COMPETITIVE LANDSCAPE
      1. Overview
      2. Competitive Analysis
      3. Market Share Analysis
      4. Major Growth Strategy in the United States Genome Editing Engineering, 
      5. Competitive Benchmarking
      6. Leading Players in Terms of Number of Developments in the United States Genome Editing Engineering, 
      7. Key Developments and Growth Strategies
        1. New Product Launch/Service Deployment
        2. Merger &Acquisitions
        3. Joint Ventures
      8. Major Players Financial Matrix 
        1. Sales & Operating Income, 2022
        2. Major Players R&D Expenditure.2022
    12. COMPANY PROFILES
      1. Merck KGaA 
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      2. Cibus
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      3. Sangamo
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      4. Editas Medicine
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      5. Precision Biosciences, 
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      6. CRISPR Therapeutics
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      7. Intellia Therapeutics, Inc., 
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      8. Caribou Biosciences, Inc.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      9. Cellectis S.A.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      10. AstraZeneca
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      11. Takara Bio USA
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      12. Horizon Discovery Group plc
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      13. Integrated DNA Technologies, Inc.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      14. Egenesis Inc.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      15. GenScript
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      16. New England Biolabs
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      17. OriGene Technologies, Inc.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      18. Lonza
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      19. Thermo Fisher Scientific, Inc.
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
    13. APPENDIX
      1. References
      2. Related Reports

    United States Genome Editing Engineering Market Segmentation

    Market Segmentation Overview

    • Detailed segmentation data will be available in the full report
    • Comprehensive analysis by multiple parameters
    • Regional and country-level breakdowns
    • Market size forecasts by segment
    Report Infographic
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