Optical Genome Mapping Market

Growing investment in R&D by major market participants, as well as increased partnerships among academic institutions and industrial partners, are driving the market growth

Market CAGR for Optical Genome Mapping is driven by the growing investment in R&D by major market participants, as well as increased partnerships among academic institutions and industrial partners. The surge in government initiatives to delve deeper into genome mapping is propelling market growth. For instance, the Government of India, Ministry of Science & Technology sanctioned a project named 'Genome India: Cataloguing the Genetic Variation in Indians' in March 2020, as reported by the Press Information Bureau.

This project, centered on Whole Genome Sequencing (WGS), aims to complete sequencing for 10,000 individuals within three years, representing the diverse population of the country. Optical genome mapping laid the groundwork for whole-genome sequencing, facilitating digital genome assembly by aligning sequenced DNA fragments to the genome map. The insights derived from whole-genome sequencing are expected to enhance the precision of future human genetics research in the country. Additionally, it will enable the development of a genome-wide association array tailored to the Indian population, leading to the creation of cost-effective precision healthcare and diagnostics for prevalent diseases.

Industry players are employing various marketing strategies such as mergers, acquisitions, and product launches. For example, in June 2022, Hamilton and Bionano Genomics, Inc. announced a collaboration to develop the Long String VANTAGE, designed for the isolation of Ultra High Molecular Weight (UHMW) DNA for optical genome mapping (OGM).

A crucial step in Bionano's sample preparation workflow is the extraction of high-quality and quantity UHMW DNA. Traditionally, this process is manually performed by highly skilled laboratory personnel, limiting the amount of DNA extracted and its usability in regular sample preparation. As a result, it is anticipated that throughout the projection period, demand for the Optical Genome Mapping Market will increase due to the Growing investment in R&D by major market participants, as well as increased partnerships among academic institutions and industrial partners. Thus, driving the Optical Genome Mapping Market revenue.

The Global Optical Genome Mapping Market Industry is experiencing rapid growth due to continuous technological advancements. Innovations in optical mapping technologies enhance the resolution and accuracy of genomic analysis, enabling researchers to identify structural variations in genomes more effectively. For instance, the introduction of high-throughput optical mapping systems has significantly reduced the time required for genome assembly. As a result, the market is projected to reach 0.26 USD Billion in 2024, with expectations of substantial growth as these technologies become more widely adopted in research and clinical settings.

By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The anticipated expansion of the Optical Genome Mapping market in North America can be attributed to several key factors. The advancement in genetic research has propelled a particular region to the forefront. In a Tedtalk Podcast episode by the United States Food and Drug Administration aired in 2021, titled "Whole Genome Sequencing in the New Era of Smarter Food Safety," the discussion centered around the increasing utilization of whole-genome sequencing in both public and private sectors for food safety.

Whole-genome sequencing (WGS) stands as a pioneering technology adopted by the FDA for innovative and health-centric purposes. By unveiling the complete DNA composition of an organism, WGS allows the FDA to gain deeper insights into genetic variations within and between species. The integration of optical genome mapping has further simplified the process of genome sequencing, facilitating the FDA in distinguishing between species with an unprecedented level of accuracy not achievable with current technologies.

Further, the major countries studied in the market report are the US, Canada, Germany, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure 2:   OPTICAL GENOME MAPPING MARKET SHARE BY REGION 2023 (USD Billion)

Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

Europe's Optical Genome Mapping Market accounts for the second-largest market share as the European optical genome mapping market is propelled by factors such as the expanding elderly population prone to genetic conditions, the expanding utilization of genome analysis in oncology, and the growing investment in genome research endeavors. In June 2023, The European Confederation of Pharmaceutical Entrepreneurs (EUCOPE), in collaboration with Exact Sciences, Guardant Health, Illumina, MSD, and Novartis, introduced the European Coalition for Access to Comprehensive Genomic Profiling (ECGP).

This coalition aims to enhance cancer care by advocating for increased routine clinical access and reimbursement of Comprehensive Genomic Profiling (CGP) across Europe. Further, the German Optical Genome Mapping Market held the largest market share, and the UK Optical Genome Mapping Market was the fastest-growing market in the European region.

The Asia-Pacific Optical Genome Mapping Market is expected to grow at the fastest CAGR from 2025 to 2034. The rising awareness of genetic disorders and the expanding accessibility of genetic testing have spurred a greater need for advanced genomic technologies to conduct precise and thorough DNA analyses.  ly, close to 8000 rare genetic diseases have been identified, with approximately 450 reported cases in India alone.

These disorders predominantly impact children and impose significant socio-economic, emotional, and physical challenges on affected families. Optical genome mapping stands out for its ability to conduct extensive genome analysis and detect structural variations over long ranges, rendering it an invaluable asset for both research and clinical purposes. Moreover, China’s Optical Genome Mapping Market held the largest market share, and the Indian Optical Genome Mapping Market was the fastest-growing market in the Asia-Pacific region.

Leading market players are investing heavily in research and development to expand their product lines, which will help the Optical Genome Mapping market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their   footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, the Optical Genome Mapping industry must offer cost-effective items.

Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the   Optical Genome Mapping industry to benefit clients and increase the market sector. In recent years, the Optical Genome Mapping industry has offered some of the most significant advantages to the field of genomics and biomedical research.

Major players in the Optical Genome Mapping Market, including Bionano Genomics, Nucleome Informatics Private Limited, Praxis Genomics, LLC, SourceBio International Limited (Source BioScience), MedGenome, INRAE (French Plant Genomic Resources Center (CNRGV)), PerkinElmer (PerkinElmer Genomics), Genohub Inc., Hofkens Lab, Cerba are attempting to increase market demand by investing in research and development operations.

BioNano Genomics provides a technology platform for the analysis of genomic DNA segments and structural variations. The company offers optical genome mapping solutions, including the Saphyr system, variant detection tools, sample preparation kits, and computational solutions for experiment management and bioinformatics processing. BioNano's software portfolio includes VIA software, Nexus Copy Number, and Nxclinical, among others.

The company's services encompass data services, OGM data services, laboratory services, and certified services. BioNano operates in China, the UK, and the US, with headquarters in San Diego, California. On June 29, 203, Bionano Genomics, Inc. unveiled the Stratys system, designed for high-throughput optical genome mapping (OGM), along with VIA software, which integrates the visualization, interpretation, and reporting of genome analysis data from OGM, microarrays, and next-generation sequencing (NGS) into one unified software platform.

Nucleome Informatics Private Limited, headquartered in India, stands out as a   customer-centric genomics and bioinformatics company. As a provider of next-generation genomics services, it prioritizes environmentally friendly research practices. The mission at Nucleome is continuous learning and scientific innovation to deliver optimal solutions that align with research objectives. Specializing in NGS and bioinformatics, Nucleome serves as a trusted research partner for scientists engaged in agri-genomics and human genomics studies.

The proficient project management team ensures successful project execution within predefined scopes. By strategically implementing customized NGS protocols and bioinformatics pipelines tailored to scientific inquiries, Nucleome has earned a reputation as a dependable research collaborator. It offers next-generation sequencing and bioinformatics services worldwide. The latest version of DrSeq has been developed, enabling scientists to analyze exome sequencing and diagnostics data efficiently. Additionally, Nucleome's genotyping solutions support researchers in pharmacogenomics and personalized medicine endeavors. The Agigenotyping solutions assist agriculture scientists in enhancing breeding programs through marker-assisted selection and GWAS.