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    Plasma Fractionation Market

    ID: MRFR/HC/5928-CR
    200 Pages
    Rahul Gotadki
    July 2025

    Plasma Fractionation Market Research Report By Application (Neurology, Hematology, General Medicine, Immunology), By Product Type (Immunoglobulin, Albumin, Coagulation Factors, Protease Inhibitors), By End User (Hospitals, Ambulatory Surgical Centers, Blood Banks, Pharmaceutical Companies), By Technology (Centrifugation, Chromatography, Precipitation, Filtration) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Plasma Fractionation Market Research Report – Global Forecast till 2035 Infographic
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    Plasma Fractionation Market Summary

    As per Market Research Future Analysis, the Plasma Fractionation Market was valued at 22.7 USD Billion in 2023 and is projected to grow to 37.5 USD Billion by 2035, with a CAGR of 4.28% from 2025 to 2035. The market is driven by increasing demand for immunoglobulin therapy, technological advancements, and rising prevalence of chronic diseases. Key players are investing in production facilities and regulatory approvals, particularly in underserved markets, enhancing access to plasma-derived therapies.

    Key Market Trends & Highlights

    The Global Plasma Fractionation Market is witnessing significant trends driven by healthcare demands and technological innovations.

    • Immunoglobulin segment expected to dominate with a valuation of 10.5 USD Billion in 2024, growing to 18.0 USD Billion by 2035.
    • North America market valued at 10.5 USD Billion in 2024, projected to reach 17.5 USD Billion by 2035.
    • Rising investment in healthcare infrastructure, with the U.S. allocating over 10% of its GDP to healthcare expenditures.

    Market Size & Forecast

    2023 Market Size USD 22.7 Billion
    2024 Market Size USD 23.66 Billion
    2035 Market Size USD 37.5 Billion
    CAGR (2025-2035) 4.28%

    Major Players

    Key companies include Octapharma, CSL Behring, Pfizer, Kedrion, Takeda Pharmaceutical, Grifols, and Baxter International.

    Plasma Fractionation Market Trends

    The Plasma Fractionation Market is experiencing significant growth driven by the increasing demand for immunoglobulins for the treatment of various diseases, particularly in the fields of immunology and hematology.

    As countries continue to prioritize healthcare expenditures, the need for effective therapies derived from human plasma has surged, fostering advancements in technology and production capabilities.

    Moreover, the rise in lifestyle-related diseases, along with an aging population, has heightened the reliance on plasma-derived products to meet therapeutic needs. Presently, there are several opportunities that could be explored within the Plasma Fractionation Market.

    The ongoing expansion of biopharmaceutical companies and research institutions looking to enhance their product offerings presents a chance for increased collaboration and innovation. Additionally, investing in research and development to improve plasma collection and fractionation techniques can lead to more efficient manufacturing processes.

    This may ensure a steady supply of high-quality plasma products while addressing potential shortages caused by growing demand. Recent trends indicate a shift towards more stringent regulatory frameworks across the globe, compelling manufacturers to comply with higher safety and quality standards in their products.

    This has led to a greater emphasis on automation and integrated systems within facilities, optimizing the production process while ensuring product integrity. Furthermore, increased awareness around the therapeutic benefits of plasma proteins has catalyzed growth opportunities in emerging markets.

    As nations aim to bolster their healthcare systems, there is a strong potential for investment in plasma fractionation technologies, setting the stage for a dynamic and competitive market landscape.

    The Global Plasma Fractionation Market is poised for robust growth, driven by increasing demand for immunoglobulins and advancements in fractionation technologies that enhance product yield and safety.

    U.S. Food and Drug Administration (FDA)

    Plasma Fractionation Market Drivers

    Market Growth Projections

    The Global Plasma Fractionation Market Industry is projected to experience substantial growth over the coming years. With a market value anticipated to reach 23.7 USD Billion in 2024, the industry is poised for expansion, driven by various factors such as increasing demand for immunoglobulins and advancements in processing technologies. By 2035, the market could potentially grow to 37.5 USD Billion, reflecting a compound annual growth rate of 4.28% from 2025 to 2035. This growth trajectory indicates a robust future for plasma fractionation, as the industry adapts to evolving healthcare needs and technological advancements.

    Rising Demand for Immunoglobulins

    The Global Plasma Fractionation Market Industry experiences a notable increase in demand for immunoglobulins, which are essential for treating various immunodeficiency disorders. This demand is driven by a growing awareness of autoimmune diseases and the need for effective therapies. In 2024, the market is projected to reach 23.7 USD Billion, reflecting the increasing reliance on plasma-derived therapies. The rising prevalence of conditions such as primary immunodeficiency and chronic inflammatory diseases further fuels this trend. As healthcare systems globally prioritize patient-centered care, the focus on immunoglobulin therapies is expected to continue, contributing to the overall growth of the Global Plasma Fractionation Market Industry.

    Regulatory Support and Quality Standards

    Regulatory frameworks and quality standards play a pivotal role in shaping the Global Plasma Fractionation Market Industry. Governments and health organizations worldwide are establishing stringent regulations to ensure the safety and efficacy of plasma-derived products. This regulatory support fosters consumer confidence and encourages investment in plasma fractionation technologies. Compliance with these standards is essential for manufacturers aiming to enter or expand within the market. As the industry adapts to evolving regulations, it is likely to witness sustained growth, with projections indicating a market value of 23.7 USD Billion in 2024. The emphasis on quality assurance and regulatory compliance is crucial for the continued success of the Global Plasma Fractionation Market Industry.

    Advancements in Plasma Processing Technologies

    Technological innovations in plasma processing are significantly influencing the Global Plasma Fractionation Market Industry. Enhanced methods such as chromatography and filtration techniques improve the efficiency and yield of plasma-derived products. These advancements not only optimize production processes but also ensure higher purity and safety of the final products. For instance, the introduction of automated systems in plasma fractionation facilities has streamlined operations, reducing costs and increasing output. As a result, the market is likely to expand, with projections indicating a growth trajectory that could see it reach 37.5 USD Billion by 2035. This technological evolution is essential for meeting the rising global demand for plasma-derived therapies.

    Growing Investment in Healthcare Infrastructure

    Investment in healthcare infrastructure is a crucial driver for the Global Plasma Fractionation Market Industry. Governments and private entities are increasingly allocating resources to enhance healthcare facilities and services, particularly in developing regions. This investment facilitates the establishment of advanced plasma fractionation centers, which are essential for producing high-quality plasma-derived products. Improved infrastructure not only supports the production of immunoglobulins and clotting factors but also enhances access to these therapies for patients. As a result, the market is poised for growth, with the potential to reach 37.5 USD Billion by 2035. The focus on strengthening healthcare systems globally is likely to have a lasting impact on the Global Plasma Fractionation Market Industry.

    Increasing Prevalence of Hemophilia and Other Bleeding Disorders

    The Global Plasma Fractionation Market Industry is significantly impacted by the rising incidence of hemophilia and other bleeding disorders. These conditions necessitate the use of clotting factor concentrates, which are derived from plasma. The increasing awareness and diagnosis of these disorders contribute to a higher demand for plasma-derived therapies. As healthcare providers focus on improving patient outcomes, the need for effective treatment options becomes paramount. This trend is expected to drive market growth, with a compound annual growth rate of 4.28% projected from 2025 to 2035. The emphasis on specialized treatments for bleeding disorders underscores the importance of the Global Plasma Fractionation Market Industry.

    Market Segment Insights

    Plasma Fractionation Market Application Insights  

    The Plasma Fractionation Market is witnessing substantial growth across various applications, reflecting its significance in the healthcare industry, particularly in the fields of Neurology, Hematology, General Medicine, and Immunology. In 2024, the market is projected to be valued at 23.66 USD Billion, with applications playing a crucial role in driving this growth. Among the applications, Hematology and General Medicine are significant contributors, demonstrating majority holdings in market value.

    Hematology is anticipated to reach 6.8 USD Billion in 2024 before growing to 10.5 USD Billion by 2035, indicating the demand for plasma-derived products in the management of blood disorders. General Medicine is also expected to show considerable growth, starting at 8.9 USD Billion in 2024 and increasing to 13.8 USD Billion by 2035.

    This reflects the essential role plasma fractionation plays in treating various conditions, from immune disorders to infections.On the other hand, Neurology is another pivotal application, valued at 5.5 USD Billion in 2024, with expectations to rise to 8.7 USD Billion by 2035.

    This indicates a growing recognition of the essential contributions of plasma-derived therapies in treating neurological disorders, which often require specialized treatments not fully addressed by conventional medicine. The Immunology application, while smaller, stands at 2.46 USD Billion in 2024 and is projected to reach 4.5 USD Billion by 2035. The growth in this area is crucial as plasma products play a vital role in immune system support and treatment of autoimmune diseases, thus highlighting its significance in patient care.

    Overall, these figures signal a strong market growth trend driven by increasing healthcare needs and advancements in plasma fractionation technology. Additionally, market growth is supported by a rise in chronic diseases and an aging population, contributing to the increasing demand for plasma-derived therapies.

    Plasma Fractionation Market Product Type Insights  

    The Plasma Fractionation Market is experiencing significant growth, projected to reach a market value of 23.66 USD Billion in 2024, driven by the increasing demand for plasma-derived therapies across various applications. The market is segmented into several product types, with Immunoglobulin, Albumin, Coagulation Factors, and Protease Inhibitors being the key categories.

    Immunoglobulin holds a major share of the market due to its essential role in treating immunodeficiencies and autoimmune disorders. Albumin, with its critical applications in managing shock and burns, is also a dominant product type, demonstrating its importance in medical treatments globally.Coagulation Factors are significant in the hemophilia treatment landscape, facilitating effective management of bleeding disorders. Protease Inhibitors

    play a vital role in therapeutic applications, particularly in antiviral and anti-inflammatory treatments. The growth in this market segment is propelled by rising healthcare investments and technological advancements, bolstering the Plasma Fractionation Market data and statistics. However, the market faces challenges, including regulatory hurdles and fluctuating plasma supply, which may impact production and distribution.

    Plasma Fractionation Market End User Insights  

    The Plasma Fractionation Market is set to experience significant growth with various end users playing crucial roles in shaping its landscape. By 2024, the market is expected to be valued at approximately 23.66 billion USD, reflecting the increasing reliance on plasma-derived therapeutics in healthcare.

    Hospitals serve as key players in this segment, leveraging plasma fractionation products for patients requiring immunoglobulins and clotting factor treatments, thus enhancing patient recovery and care standards.

    Ambulatory Surgical Centers, known for their emphasis on outpatient procedures, also benefit from the availability of plasma therapies, ensuring effective treatments while optimizing operational efficiencies.Blood Banks are fundamental to this market as they are responsible for collecting and processing plasma, ensuring a steady supply for various applications in medicine.

    Pharmaceutical Companies dominate this segment by developing and manufacturing advanced plasma-derived medicines, contributing significantly to the Plasma Fractionation Market revenue.

    These factors collectively highlight the diverse applications and the importance of each end user, driving the market towards substantial growth amidst evolving healthcare demands.

    Plasma Fractionation Market Technology Insights  

    The Plasma Fractionation Market within the Technology segment is a crucial area, expected to reach a valuation of 23.66 billion USD by 2024. This market encompasses various techniques essential for the separation and purification of plasma proteins, with methods such as Centrifugation, Chromatography, Precipitation, and Filtration playing significant roles.

    Centrifugation is widely utilized for its efficiency in separating components based on density, while Chromatography enhances the purity of plasma derivatives, making it a preferred choice in Research and Development.Precipitation offers a cost-effective solution for isolating proteins, and Filtration provides a reliable method for removing impurities. These techniques not only contribute to the efficacy of plasma treatments but also drive advancements in therapeutic applications worldwide.

    The market growth stems from an increasing demand for clotting factor concentrates and immunoglobulins, facilitating improved patient outcomes and addressing critical health challenges globally. As a result, the exploration of innovative technologies in this segment promises to elevate the standards of healthcare solutions derived from plasma fractionation.

    Get more detailed insights about Plasma Fractionation Market Research Report – Global Forecast till 2035

    Regional Insights

    The Plasma Fractionation Market showcases a diverse regional landscape, with significant contributions from various areas. In 2024, North America holds a majority holding with a valuation of 10.5 USD Billion, growing to 16.5 USD Billion by 2035. This dominance is driven by advanced healthcare infrastructure and increased demand for immunoglobulins.

    Europe follows with a valuation of 6.5 USD Billion in 2024, reflecting a strong focus on Research and Development of plasma-derived therapies, expected to reach 10.0 USD Billion in 2035. South America is valued at 2.0 USD Billion in 2024, highlighting a growing interest in plasma products for treating diverse medical conditions.

    Asia Pacific, with a valuation of 4.0 USD Billion in 2024, is anticipated to grow to 6.5 USD Billion by 2035, benefiting from expanding healthcare initiatives and population growth.

    The Middle East and Africa segment, although relatively smaller at 0.66 USD Billion in 2024, is forecasted to rise to 1.5 USD Billion by 2035, driven by increasing awareness of plasma therapies.

    Overall, the Plasma Fractionation Market data indicates significant growth potential across these regions, influenced by innovations in treatment options and expanding healthcare access.

    Plasma Fractionation Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Plasma Fractionation Market has witnessed significant growth over recent years, driven by the increasing demand for plasma-derived therapies and the rising prevalence of various disorders such as hemophilia, immune deficiencies, and certain cancers.

    This market is characterized by the presence of numerous key players, each striving to enhance their product offerings and expand their market share.

    Competitive insights into this market reveal a landscape where innovation, strategic partnerships, and regulatory considerations play vital roles. Companies are focusing on research and development to improve existing products, while also exploring new therapeutic areas to address unmet medical needs.

    Additionally, the market is experiencing consolidation through mergers and acquisitions as organizations aim to leverage synergies and streamline their operations.

    LFB Group has established itself as a prominent player in the Plasma Fractionation Market through its emphasis on high-quality products and patient-centric solutions. The company benefits from its strong research and development capabilities, allowing it to introduce innovative plasma-derived therapies that meet the increasing global healthcare demands.

    LFB Group's market presence is bolstered by its commitment to safety and efficacy, which resonates well with healthcare providers and patients alike.

    The organization has developed a wide range of immunoglobulin and clotting factor products that cater to various therapeutic needs, making it a trusted name within the industry. Its collaborations with academic institutions and healthcare organizations further enhance its competitive position, emphasizing its role as a leader in providing specialized plasma-derived therapies globally.

    Takeda Pharmaceutical is another key participant in the Plasma Fractionation Market, recognized for its extensive portfolio of biologics and plasma-derived therapies. The company offers a range of products, including immunoglobulins, clotting factors, and other therapeutic proteins, which serve various medical conditions.

    Takeda's strength lies in its robust global presence, allowing it to reach a wide patient population and address local healthcare challenges effectively. With a strong focus on research and strategic partnerships, Takeda is actively engaged in mergers and acquisitions to enhance its technological capabilities and expand its product offerings.

    These initiatives not only bolster its market position but also promote innovation in plasma fractionation technologies. The company’s commitment to patient access and improving health outcomes further solidifies its standing as a leader in the global market for plasma-derived therapies, enhancing its competitiveness in this dynamic industry.

    Key Companies in the Plasma Fractionation Market market include

    Industry Developments

    Significant news developments in the Plasma Fractionation Market include accelerated growth driven by increasing demand for immunoglobulin therapies and advancements in plasma-derived products. Companies like Grifols and CSL Behring are enhancing their production capabilities through investments in new facilities and technology.

    In October 2023, Takeda Pharmaceutical announced plans to expand its manufacturing footprint in response to heightened demand, illustrating the competitive landscape.

    Recent mergers and acquisitions have also shaped the industry; for instance, in September 2023, ADMA Biologics finalized its acquisition of a specialized plasma collection center to strengthen its supply chain.

    Additionally, in December 2022, Octapharma and Hualan Biological Engineering formed a collaborative agreement to enhance production efficiency, indicating strategic alliances within the sector.

    Moreover, technological advancements in plasma fractionation processes are improving yield and reducing costs, benefiting companies like Emergent BioSolutions and Biotest AG.

    The overall market valuation continues to grow as consumer awareness of plasma-derived therapies rises, with emerging markets contributing to increasing investments. This growth trend emphasizes the importance of operational excellence and innovation in the industry's future endeavors while navigating regulatory landscapes in various global regions.

    Future Outlook

    Plasma Fractionation Market Future Outlook

    The Plasma Fractionation Market is projected to grow at a 4.28% CAGR from 2024 to 2035, driven by increasing demand for immunoglobulins and advancements in fractionation technologies.

    New opportunities lie in:

    • Invest in R&D for novel therapies utilizing plasma-derived products.
    • Expand distribution networks in emerging markets to capture growing demand.
    • Leverage automation technologies to enhance production efficiency and reduce costs.

    By 2035, the Plasma Fractionation Market is expected to be robust, reflecting substantial growth and innovation.

    Market Segmentation

    Plasma Fractionation Market End User Outlook

    • Hospitals
    • Ambulatory Surgical Centers
    • Blood Banks
    • Pharmaceutical Companies

    Plasma Fractionation Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa 

    Plasma Fractionation Market Technology Outlook

    • Centrifugation
    • Chromatography
    • Precipitation
    • Filtration

    Plasma Fractionation Market Application Outlook

    • Neurology
    • Hematology
    • General Medicine
    • Immunology

    Plasma Fractionation Market Product Type Outlook

    • Immunoglobulin
    • Albumin
    • Coagulation Factors
    • Protease Inhibitors

    Report Scope

    Report Attribute/Metric

    Details

    Market Size 2023

    22.7(USD Billion)

    Market Size 2024

    23.66(USD Billion)

    Market Size 2035

    37.5(USD Billion)

    Compound Annual Growth Rate (CAGR)

    4.28% (2025 - 2035)

    Report Coverage

    Revenue Forecast, Competitive Landscape, Growth Factors, and Trends

    Base Year

    2024

    Market Forecast Period

    2025 - 2035

    Historical Data

    2019 - 2024

    Market Forecast Units

    USD Billion

    Key Companies Profiled

    LFB Group, Takeda Pharmaceutical, Octapharma, Grifols, Popharma, ADMA Biologics, Baxter International, Biotest AG, CSL Behring, Indian Immunologicals, Hualan Biological Engineering, Prothena Corporation, Shire, Kedrion Biopharma

    Segments Covered

    Application, Product Type, End User, Technology, Regional

    Key Market Opportunities

    Rising demand for immunoglobulins, Increasing prevalence of bleeding disorders, Expanding applications in therapeutics, Growth in aging population, Advancements in fractionation technologies

    Key Market Dynamics

    Rising demand for immunoglobulin therapies, Increasing prevalence of bleeding disorders, Technological advancements in fractionation, Growing geriatric population, Expanding pharmaceutical applications of plasma products

    Countries Covered

    North America, Europe, APAC, South America, MEA

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What was the market size of the Plasma Fractionation Market in 2024?

    The Plasma Fractionation Market was valued at 23.66 billion USD in 2024.

    What will be the projected market size by 2035?

    By 2035, the Plasma Fractionation Market is anticipated to reach a value of 37.5 billion USD.

    What is the expected CAGR for the Plasma Fractionation Market from 2025 to 2035?

    The Plasma Fractionation Market is projected to have a CAGR of 4.28% from 2025 to 2035.

    Which region was dominated the Plasma Fractionation Market in 2024?

    North America was dominated the Plasma Fractionation Market with a value of 10.5 billion USD in 2024.

    What will be the market size of North America in 2035?

    In 2035, the North American market is projected to grow to 16.5 billion USD.

    Which application segment had the highest market value in 2024?

    General Medicine had the highest market value at 8.9 billion USD in 2024.

    What is the forecasted market size for the Hematology application by 2035?

    The Hematology application segment is anticipated to reach a market size of 10.5 billion USD by 2035.

    Who are the major players in the Plasma Fractionation Market?

    Major players include LFB Group, Takeda Pharmaceutical, Octapharma, Grifols, and CSL Behring.

    What was the market size for Immunology application in 2024?

    The Immunology application segment was the market size of 2.46 billion USD in 2024.

    What is the expected market size for the Asia Pacific region in 2035?

    The Asia Pacific region is expected to reach a market size of 6.5 billion USD by 2035.

    Plasma Fractionation Market Research Report – Global Forecast till 2035 Infographic
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