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    Non Alcoholic Fatty Liver Disease Market

    ID: MRFR/HC/40511-HCR
    100 Pages
    Rahul Gotadki
    September 2025

    Non-Alcoholic Fatty Liver Disease NAFLD Market Research Report By Diagnosis Method (Ultrasound, CT Scan, MRI, Liver Biopsy), By Treatment Type (Lifestyle Changes, Medications, Surgical Procedures, Nutritional Supplements), By Patient Demographics (Adults, Children, Elderly), By Complication Type (Fibrosis, Cirrhosis, Hepatocellular Carcinoma) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2035

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    Non-Alcoholic Fatty Liver Disease NAFLD Market Research Report — Global Forecast till 2032 Infographic
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    Non Alcoholic Fatty Liver Disease Market Summary

    The Global Non-Alcoholic Fatty Liver Disease NAFLD Market is projected to grow significantly over the next decade.

    Key Market Trends & Highlights

    Non-Alcoholic Fatty Liver Disease NAFLD Key Trends and Highlights

    • The market is valued at 2.01 USD Billion in 2024 and is expected to reach 3.8 USD Billion by 2035.
    • The compound annual growth rate (CAGR) for the period from 2025 to 2035 is estimated at 5.96%.
    • This growth trajectory indicates a robust demand for NAFLD treatment and management solutions.
    • Growing adoption of innovative treatment options due to increasing prevalence of obesity is a major market driver.

    Market Size & Forecast

    2024 Market Size 2.01 (USD Billion)
    2035 Market Size 3.8 (USD Billion)
    CAGR (2025-2035) 5.96%

    Major Players

    Genfit, Intercept Pharmaceuticals, Bristol-Myers Squibb, Roche, Novartis, Eisai, Merck, Sanofi, Boehringer Ingelheim, Pfizer, AstraZeneca, Gilead Sciences, Madrigal Pharmaceuticals, AbbVie, Amgen

    Non Alcoholic Fatty Liver Disease Market Trends

    The Global NAFLD (Non-Alcoholic Fatty Liver Disease) Market is growing at a notable pace, primarily due to certain market drivers. The growing population of obese individuals, as well as people suffering from various forms of metabolic syndrome, has led to an increase in NAFLD cases, which seems to be a reason for greater awareness and demand for some sort of effective treatment for NAFLD. Now, improvements in diagnostic technologies allow us to diagnose NAFLD at an earlier stage, which is fuelling the growth of the market.

    An increasing interest in non-alcoholic fatty liver disease is also motivated by the interest in preventive healthcare and lifestyle changes. Looking at the opportunities, there are great possibilities that one can explore in order to cater to the ever increasing healthcare demands of NAFLD patients.

    From a pharmaceutical perspective, there are novel opportunities in the development of therapeutic targets for fat and inflammation in the liver. The growth of Telehealth is also opening new avenues for education and commercial management of patients as people can be assisted without appropriate boundaries. Even the rolled out partnerships between healthcare and technology firm may assist in better disease management by providing tailored treatments utilizing algorithms. There are emerging patterns that show more and more clinical trials are being done for diverse pharmacological and non-pharmacological treatment approaches.

    Adoption of alternative liver biopsy techniques to reduce the invasiveness of the procedure is being funded which could benefit patients and the healthcare systems.

    In addition, there is an increase in interest in these ‘nutritional medicines’ as research on diet and NAFLD progresses. All in all, this set of drivers, opportunities and trends presents an ever changing and evolving landscape for the NAFLD market and how it will meet global patients’ expectations.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    The increasing prevalence of Non-Alcoholic Fatty Liver Disease underscores a pressing need for enhanced public health strategies and interventions to address this growing health concern.

    Centers for Disease Control and Prevention (CDC)

    Non Alcoholic Fatty Liver Disease Market Drivers

    Market Growth Projections

    The Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry is poised for substantial growth, with projections indicating a market size of 2.01 USD Billion in 2024 and an anticipated increase to 3.8 USD Billion by 2035. This growth trajectory suggests a compound annual growth rate (CAGR) of 5.96% from 2025 to 2035. Such figures reflect the increasing recognition of NAFLD as a significant public health concern, prompting investments in research, treatment options, and healthcare infrastructure. The market's expansion is likely to be driven by various factors, including advancements in diagnostics, rising obesity rates, and a growing focus on preventive healthcare.

    Rising Incidence of Diabetes

    The rising incidence of diabetes globally is a significant factor impacting the Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry. Diabetes is a major risk factor for NAFLD, and as the number of individuals diagnosed with diabetes continues to increase, so does the potential for NAFLD cases. The International Diabetes Federation reports that approximately 537 million adults were living with diabetes in 2021, a figure that is projected to rise. This trend suggests a corresponding increase in NAFLD cases, thereby driving market growth. The interrelation between these conditions underscores the need for integrated treatment approaches, which could further enhance market dynamics.

    Rising Prevalence of Obesity

    The increasing prevalence of obesity globally is a critical driver of the Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry. As obesity rates rise, so does the incidence of NAFLD, which is closely linked to metabolic syndrome. In 2024, the market is projected to reach 2.01 USD Billion, reflecting the growing awareness and diagnosis of this condition. The World Health Organization indicates that obesity has nearly tripled since 1975, highlighting a concerning trend that could propel market growth. This correlation suggests that as more individuals become aware of their health, the demand for NAFLD-related treatments and interventions will likely increase, further expanding the market.

    Increased Awareness and Education

    Growing awareness and education regarding liver health and NAFLD are pivotal in shaping the Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry. Public health campaigns and educational initiatives have led to a better understanding of the risks associated with NAFLD, prompting individuals to seek medical advice and screening. This heightened awareness is expected to contribute to a compound annual growth rate (CAGR) of 5.96% from 2025 to 2035. As more people become informed about the implications of NAFLD, the demand for preventive measures and treatment options is likely to surge, further driving market growth.

    Advancements in Diagnostic Technologies

    Technological advancements in diagnostic methods for NAFLD are significantly influencing the Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry. Innovations such as non-invasive imaging techniques and biomarkers have improved the accuracy of NAFLD diagnosis, allowing for earlier detection and management. This shift is crucial, as timely intervention can prevent disease progression. The market is expected to grow to 3.8 USD Billion by 2035, driven by these advancements. Enhanced diagnostic capabilities not only facilitate better patient outcomes but also encourage healthcare providers to adopt more proactive approaches in managing liver health, thereby expanding the market's reach.

    Growing Demand for Lifestyle Modifications

    There is a growing demand for lifestyle modifications as a preventive strategy against NAFLD, which is influencing the Global Non-Alcoholic Fatty Liver Disease NAFLD Market Industry. As healthcare professionals increasingly recommend dietary changes and physical activity to combat NAFLD, the market for related products and services is expanding. This trend is particularly relevant as individuals seek holistic approaches to health management. The emphasis on lifestyle changes is expected to contribute to the market's growth trajectory, as more people recognize the importance of maintaining liver health. This shift towards prevention could lead to a more sustainable market environment.

    Market Segment Insights

    Non-Alcoholic Fatty Liver Disease NAFLD Market Diagnosis Method Insights

    The Global Non-Alcoholic Fatty Liver Disease (NAFLD) Market is experiencing notable progression in various diagnosis methods, reflecting the increasing awareness and prevalence of the condition. By 2024, the market will be valued at approximately 2.01 USD Billion, symbolizing a robust landscape for the diagnostic segment, with a notable focus on medical imaging techniques. As the population continues to grapple with health complications associated with non-alcoholic fatty liver disease, it is expected that the methods employed for diagnosis will also see significant advancements and acceptance.

    Ultrasound emerges as a dominant method in this segment, showcasing a valuation of 0.8 USD Billion in 2024 with projected growth to 1.5 USD Billion by 2035, indicating its substantial role in preliminary assessments due to its non-invasive nature and accessibility. In contrast, the CT Scan is valued at 0.4 USD Billion in 2024, growing to 0.7 USD Billion by 2035, signifying its emerging relevance in offering detailed insights about liver conditions. 

    The ability of CT scans to provide clearer images of liver structures contributes to their significance, particularly in more complex cases of NAFLD. The MRI method, with a market valuation starting at 0.26 USD Billion in 2024 and expected to reach 0.5 USD Billion by 2035, plays a pivotal role in offering high-resolution imaging that can identify subtle changes in liver tissue, making it invaluable for diagnosis where precision is required. Meanwhile, Liver Biopsy, starting at 0.55 USD Billion in 2024 and anticipated to double to 1.1 USD Billion by 2035, is recognized as the gold standard for definitive diagnosis.

    Its significance lies in the ability to assess the degree of liver inflammation and fibrosis, thereby guiding treatment options. The balance among these diagnosis methods illustrates a diversifying landscape, where each method holds its unique place in clinical practice. As the Non-Alcoholic Fatty Liver Disease NAFLD Market evolves, the steady market growth across these diagnostic processes reflects the increasing demand for accurate and efficient diagnostic tools, indicating both growth drivers and opportunities within the industry.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Non-Alcoholic Fatty Liver Disease NAFLD Market Treatment Type Insights

    The Non-Alcoholic Fatty Liver Disease NAFLD Market is projected to be valued at 2.01 USD Billion in 2024, highlighting the growing importance of various treatment types. Within this comprehensive market, key treatment approaches include Lifestyle Changes, Medications, Surgical Procedures, and Nutritional Supplements. Lifestyle Changes often play a critical role in management, as they address core risk factors associated with the disease. Medications are gaining traction, especially in light of increasing incidences of NAFLD, providing targeted therapies for patients.Surgical Procedures, although less common, are essential for cases where alternative treatments fail, significantly impacting patient outcomes.

    Meanwhile, Nutritional Supplements are emerging as a noteworthy option, with an increasing consumer focus on preventive health measures and dietary management. Overall, the Non-Alcoholic Fatty Liver Disease NAFLD Market segmentation reveals dynamic growth prospects driven by an increasing prevalence of the condition, greater awareness, and evolving treatment modalities. This market showcases significant opportunities and challenges, providing a landscape ripe for innovation in therapeutic strategies, all contributing to the overall growth of the market.

    Non-Alcoholic Fatty Liver Disease NAFLD Market Patient Demographics Insights

    The Global Non-Alcoholic Fatty Liver Disease (NAFLD) Market is anticipated to reach a value of 2.01 billion USD by 2024, reflecting an increasing awareness of liver health across various patient demographics. Among these, adults represent a significant portion of the NAFLD population, driven by rising obesity rates and sedentary lifestyles. Children's growing susceptibility to NAFLD emphasizes the need for educational initiatives around health and nutrition, as early intervention can play a crucial role in disease management.

    Meanwhile, the elderly segment is also essential, as age-related metabolic changes increase the risk of liver diseases.Overall, the Non-Alcoholic Fatty Liver Disease NAFLD Market segmentation highlights the importance of targeted treatment and preventative strategies tailored to these distinct age groups, ultimately impacting market growth and product development in this industry. With the anticipated expansion, understanding the nuances of each demographic is vital for stakeholders aiming to address the health challenges posed by NAFLD.

    Non-Alcoholic Fatty Liver Disease NAFLD Market Complication Type Insights

    The Non-Alcoholic Fatty Liver Disease NAFLD Market focuses significantly on the Complication Type segment, which includes major categories such as Fibrosis, Cirrhosis, and Hepatocellular Carcinoma. In 2024, this market is expected to achieve a valuation of approximately 2.01 billion USD, reflecting robust growth trends due to the increasing prevalence of liver diseases and rising awareness of related health issues. Fibrosis, as an early-stage complication, plays a crucial role in disease progression and management.

    Cirrhosis represents a more advanced state and is critical for understanding treatment approaches and healthcare ramifications.Hepatocellular Carcinoma emerges as a severe consequence of prolonged liver disease, further emphasizing the importance of early intervention strategies within the market. The necessity for effective medical treatments and monitoring systems is fueling market growth, while challenges remain, such as the high cost of advanced therapies and varying healthcare regulations across regions.

    Opportunities abound in the form of novel therapeutic developments aimed at addressing these complications, potentially driving the Non-Alcoholic Fatty Liver Disease NAFLD Market revenue upward as healthcare providers seek effective solutions for patient management.

    Get more detailed insights about Non-Alcoholic Fatty Liver Disease NAFLD Market Research Report — Global Forecast till 2032

    Regional Insights

    The Non-Alcoholic Fatty Liver Disease NAFLD Market is witnessing a notable regional distribution, with North America holding a significant share, valued at 0.85 USD Billion in 2024 and projected to grow to 1.5 USD Billion by 2035, showcasing its major market presence. Europe follows closely with a valuation of 0.68 USD Billion in 2024, expected to rise to 1.25 USD Billion in 2035, highlighting its importance in the market growth dynamics.

    The Asia-Pacific (APAC) region is also experiencing steady growth, with a value of 0.38 USD Billion in 2024 and a forecast of 0.7 USD Billion by 2035, driven by increasing healthcare awareness and lifestyle changes.Meanwhile, South America and the Middle East Africa (MEA) represent smaller market shares, with South America valued at 0.05 USD Billion and projected to reach 0.15 USD Billion, while MEA is valued at 0.05 USD Billion and expected to grow to 0.2 USD Billion.

    The diverse regional insights into the Non-Alcoholic Fatty Liver Disease NAFLD Market segmentation reflect varying levels of healthcare infrastructure and awareness, which significantly influence disease management and treatment availability across different geographical regions.

    Non-Alcoholic Fatty Liver Disease NAFLD Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Non-Alcoholic Fatty Liver Disease NAFLD Market is currently witnessing significant growth driven by increasing awareness of liver health, rising obesity rates, and the growing prevalence of metabolic syndrome. As the understanding of NAFLD progresses, the market landscape has become increasingly competitive, with numerous pharmaceutical companies vying for market share and developing innovative treatment options. Therapies aimed at managing or reversing the effects of NAFLD are being prioritized, propelling research and development efforts forward.

    This competitive environment is exacerbated by ongoing clinical trials and the need for effective solutions, which underscores the necessity for key players in the market to differentiate their offerings based on efficacy, safety, and overall patient outcomes. The dynamic nature of the market is shaped by collaborations, partnerships, and an emphasis on scientific innovation, ultimately seeking to address the diverse needs of healthcare providers and patients suffering from this condition.

    Genfit is a prominent player within the Non-Alcoholic Fatty Liver Disease NAFLD Market, recognized for its focus on liver disease and its commitment to the development of novel therapies. The company has established a strong pipeline, with certain products that are specifically targeted toward addressing the underlying mechanisms of NAFLD, thereby offering an attractive value proposition. Genfit's strengths lie in its innovative approach to drug development, which emphasizes both the scientific robustness and therapeutic potential of its candidates.

    With a keen understanding of the complexities associated with liver diseases, the company has positioned itself as a leader in the development of non-invasive diagnostic tools and treatment options tailored to varying stages of NAFLD. Additionally, Genfit's collaborations and partnerships enhanced its capabilities, allowing for a broader reach and impact within the healthcare sector focused on liver health. Intercept Pharmaceuticals, on the other hand, has made significant strides in the Non-Alcoholic Fatty Liver Disease NAFLD Market by focusing on liver-targeted therapies that have shown promise in clinical trials. 

    The company is committed to offering patients effective treatments that address both the inflammatory and fibrotic aspects of the disease. Intercept's expertise in the field is backed by extensive clinical research, which lends credibility to its product offerings and positions it favorably against competitors. The company has capitalized on its understanding of the essential role that metabolism and liver function play in overall health, leading to the development of targeted therapies that set it apart in the NAFLD landscape.

    Intercept Pharmaceuticals' strategic focus on advancing its therapeutic pipeline, combined with its robust data supporting the efficacy of its offerings, reinforces its competitive standing and enhances its reputation among healthcare providers and patients alike in the realm of liver disease management.

    Key Companies in the Non Alcoholic Fatty Liver Disease Market market include

    Industry Developments

    • Q1 2024: FDA approves Madrigal Pharmaceuticals' liver disease drug Madrigal Pharmaceuticals received FDA approval for its drug resmetirom, the first approved treatment for nonalcoholic steatohepatitis (NASH), a severe form of non-alcoholic fatty liver disease.
    • Q1 2024: Madrigal Pharmaceuticals Announces FDA Approval of Rezdiffra (resmetirom) for the Treatment of Adults with Noncirrhotic NASH with Moderate to Advanced Fibrosis Madrigal Pharmaceuticals announced that the U.S. FDA approved Rezdiffra (resmetirom) for adults with noncirrhotic NASH with moderate to advanced fibrosis, marking the first approved therapy for this condition.
    • Q2 2024: Pfizer Invests $100 Million in NASH Drug Developer Akero Therapeutics Pfizer made a $100 million equity investment in Akero Therapeutics to support the development of its lead NASH drug candidate, efruxifermin, which is in late-stage clinical trials.
    • Q2 2024: Akero Therapeutics Announces $100 Million Private Placement Financing Akero Therapeutics announced a $100 million private placement financing led by Pfizer to advance its clinical programs for nonalcoholic steatohepatitis (NASH).
    • Q2 2024: Gilead Sciences and Novo Nordisk Announce Research Collaboration to Advance NASH Combination Therapies Gilead Sciences and Novo Nordisk entered a research collaboration to develop and commercialize combination therapies for nonalcoholic steatohepatitis (NASH).
    • Q2 2024: Inventiva Announces FDA Fast Track Designation for Lanifibranor in NASH Inventiva received FDA Fast Track designation for its investigational drug lanifibranor for the treatment of nonalcoholic steatohepatitis (NASH).
    • Q3 2024: Novo Nordisk to Acquire NASH Drugmaker Versanis for $1.1 Billion Novo Nordisk agreed to acquire Versanis, a biotechnology company developing therapies for nonalcoholic steatohepatitis (NASH), in a deal valued at $1.1 billion.
    • Q3 2024: Versanis Bio Announces Acquisition by Novo Nordisk Versanis Bio announced its acquisition by Novo Nordisk, which aims to expand its pipeline in metabolic and liver diseases, including NASH.
    • Q3 2024: 89bio Raises $60 Million in Public Offering to Advance NASH Pipeline 89bio completed a $60 million public offering to fund the continued development of its lead NASH drug candidate, pegozafermin.
    • Q4 2024: FDA Grants Breakthrough Therapy Designation to Viking Therapeutics’ VK2809 for NASH Viking Therapeutics received FDA Breakthrough Therapy designation for VK2809, an investigational treatment for nonalcoholic steatohepatitis (NASH).
    • Q1 2025: Gilead Sciences Announces Opening of New Research Facility Focused on Liver Diseases Gilead Sciences opened a new research facility dedicated to advancing therapies for liver diseases, including nonalcoholic fatty liver disease (NAFLD) and NASH.
    • Q2 2025: Eli Lilly Announces Partnership with Regulus Therapeutics to Develop NAFLD Therapies Eli Lilly entered a partnership with Regulus Therapeutics to co-develop novel therapies targeting nonalcoholic fatty liver disease (NAFLD).

    Future Outlook

    Non Alcoholic Fatty Liver Disease Market Future Outlook

    The Non-Alcoholic Fatty Liver Disease market is projected to grow at a 5.96% CAGR from 2024 to 2035, driven by rising obesity rates, increased awareness, and advancements in treatment options.

    New opportunities lie in:

    • Develop innovative non-invasive diagnostic tools to enhance early detection.
    • Invest in personalized medicine approaches for tailored NAFLD treatments.
    • Expand telehealth services to improve patient access to NAFLD management.

    By 2035, the NAFLD market is expected to exhibit robust growth, reflecting evolving treatment paradigms and heightened awareness.

    Market Segmentation

    Non-Alcoholic Fatty Liver Disease NAFLD Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Non-Alcoholic Fatty Liver Disease NAFLD Market Treatment Type Outlook

    • Lifestyle Changes
    • Medications
    • Surgical Procedures
    • Nutritional Supplements

    Non-Alcoholic Fatty Liver Disease NAFLD Market Diagnosis Method Outlook

    • Ultrasound
    • CT Scan
    • MRI
    • Liver Biopsy

    Non-Alcoholic Fatty Liver Disease NAFLD Market Complication Type Outlook

    • Fibrosis
    • Cirrhosis
    • Hepatocellular Carcinoma

    Non-Alcoholic Fatty Liver Disease NAFLD Market Patient Demographics Outlook

    • Adults
    • Children
    • Elderly

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 1.89(USD Billion)
    Market Size 2024 2.01(USD Billion)
    Market Size 2035 3.8(USD Billion)
    Compound Annual Growth Rate (CAGR) 5.98% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled Genfit, Intercept Pharmaceuticals, BristolMyers Squibb, Roche, Novartis, Eisai, Merck, Sano, Boehringer Ingelheim, Pfizer, AstraZeneca, Gilead Sciences, Madrigal Pharmaceuticals, AbbVie, Amgen
    Segments Covered Diagnosis Method, Treatment Type, Patient Demographics, Complication Type, Regional
    Key Market Opportunities Increase in obesity prevalence, Growing awareness and education, Advancements in diagnostic technologies, Development of targeted therapies, Rising demand for lifestyle management solutions
    Key Market Dynamics rising obesity prevalence, increasing healthcare expenditure, advancing diagnostic techniques, growing awareness campaigns
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the expected market size of the Non-Alcoholic Fatty Liver Disease NAFLD Market in 2024?

    The Non-Alcoholic Fatty Liver Disease NAFLD Market is expected to be valued at 2.01 USD Billion in 2024.

    What will the market value of the Non-Alcoholic Fatty Liver Disease NAFLD Market be by 2035?

    By 2035, the Non-Alcoholic Fatty Liver Disease NAFLD Market is anticipated to reach a value of 3.8 USD Billion.

    What is the expected CAGR for the Non-Alcoholic Fatty Liver Disease NAFLD Market from 2025 to 2035?

    The expected CAGR for the Non-Alcoholic Fatty Liver Disease NAFLD Market from 2025 to 2035 is 5.98%.

    Which region is projected to have the highest market value for the Non-Alcoholic Fatty Liver Disease NAFLD Market in 2035?

    North America is projected to have the highest market value at 1.5 USD Billion for the Non-Alcoholic Fatty Liver Disease NAFLD Market in 2035.

    What is the projected market size for the Ultrasound diagnosis method in the Non-Alcoholic Fatty Liver Disease NAFLD Market by 2035?

    The projected market size for the Ultrasound diagnosis method is 1.5 USD Billion by 2035.

    Who are some key players in the Non-Alcoholic Fatty Liver Disease NAFLD Market?

    Key players in the Non-Alcoholic Fatty Liver Disease NAFLD Market include Genfit, Intercept Pharmaceuticals, Bristol Myers Squibb, and Roche.

    What will the value of the Liver Biopsy diagnosis method be in the Non-Alcoholic Fatty Liver Disease NAFLD Market in 2035?

    The Liver Biopsy diagnosis method is expected to be valued at 1.1 USD Billion in 2035.

    What is the expected market value for the CT Scan diagnosis method in the Non-Alcoholic Fatty Liver Disease NAFLD Market by 2035?

    The expected market value for the CT Scan diagnosis method is 0.7 USD Billion by 2035.

    Which region is expected to show significant growth in the Non-Alcoholic Fatty Liver Disease NAFLD Market?

    The Europe region is expected to show significant growth, reaching a market value of 1.25 USD Billion by 2035.

    What is the projected market size for the MRI diagnosis method in 2024 for the Non-Alcoholic Fatty Liver Disease NAFLD Market?

    The projected market size for the MRI diagnosis method in 2024 is 0.26 USD Billion.

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