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    Liquid Biopsy Market

    ID: MRFR/HC/0239-CR
    171 Pages
    Kinjoll Dey
    February 2023

    Liquid Biopsy Market Research Report By Application (Cancer Diagnosis, Treatment Monitoring, Recurrence Monitoring, Clinical Trials, Research Applications), By Sample Type (Blood, Urine, Saliva, Pleural Fluid, Cerebrospinal Fluid), By Technology (Next Generation Sequencing, Digital PCR, Microfluidics, Exosome Isolation, Circulating Tumor Cells), By End Use (Hospitals, Diagnostic Laboratories, Research Institutes, Pharmaceutical Companies) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast ...

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    Liquid Biopsy Market Research Report - Global Forecast to 2035 Infographic
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    Liquid Biopsy Market Summary

    As per Market Research Future analysis, the Liquid Biopsy Market was valued at 8.1 USD Billion in 2023 and is projected to grow to 22.88 USD Billion by 2035, with a CAGR of 11.60% from 2025 to 2035. The market is driven by the increasing prevalence of cancer, technological advancements, and the demand for non-invasive diagnostic methods. Liquid biopsies are preferred for monitoring treatment responses and detecting recurrences, aligning with the shift towards personalized medicine. Key players are innovating to enhance diagnostic capabilities, supported by regulatory approvals and collaborations.

    Key Market Trends & Highlights

    The Liquid Biopsy Market is experiencing significant growth driven by technological advancements and increasing cancer prevalence.

    • Market Size in 2023: 8.1 USD Billion; Expected to reach 22.88 USD Billion by 2035.
    • CAGR from 2025 to 2035: 11.60%; indicating robust growth potential.
    • Cancer Diagnosis segment expected to reach 2.2 USD Billion in 2024, dominating the market.
    • North America projected to hold a market value of 2.5 USD Billion in 2024, leading regional growth.

    Market Size & Forecast

    2023 Market Size USD 8.1 Billion
    2024 Market Size USD 8.9 Billion
    2035 Market Size USD 22.88 Billion
    CAGR (2025-2035) 11.60%

    Major Players

    Key players include GRAIL, Natera, Foundation Medicine, Exact Sciences, Thermo Fisher Scientific, and Illumina.

    Liquid Biopsy Market Trends

    Advancements in technology and an increasing emphasis on early cancer detection are driving significant trends in the Global Liquid Biopsy Market. Liquid biopsy techniques are increasingly preferred for the purpose of monitoring treatment responses and detecting cancer recurrences due to their non-invasive nature.

    This trend is primarily driven by the increasing prevalence of cancer and the growing awareness of personalized medicine, which is compelling healthcare providers and researchers to pursue innovative diagnostic solutions.

    The increasing adoption of liquid biopsy technologies is reshaping cancer diagnostics, offering a less invasive alternative that enhances early detection and monitoring of treatment responses.

    U.S. National Institutes of Health (NIH)

    Liquid Biopsy Market Drivers

    Rising Incidence of Cancer

    The increasing prevalence of cancer globally serves as a primary driver for the Global Liquid Biopsy Market Industry. As cancer cases rise, the demand for early detection and monitoring solutions intensifies. Liquid biopsies offer a non-invasive alternative to traditional tissue biopsies, allowing for the analysis of circulating tumor DNA. For instance, the World Health Organization indicates that cancer cases are expected to reach 30 million by 2040. This growing patient population is likely to propel the market, with projections estimating the Global Liquid Biopsy Market to reach 8.9 USD Billion in 2024 and potentially 22.9 USD Billion by 2035.

    Market Segment Insights

    Liquid Biopsy Market Application Insights

    The Global Liquid Biopsy Market in terms of application has shown considerable growth and importance, with various areas such as Cancer Diagnosis, Treatment Monitoring, Recurrence Monitoring, Clinical Trials, and Research Applications driving this trend.

    In 2024, the valuation for Cancer Diagnosis is expected to reach approximately 2.2 USD Billion, solidifying its position as the dominant segment within the market. This is largely due to the increasing prevalence of cancer and the necessity for early detection, which enhances treatment outcomes and helps tailor therapy for patients.

    Treatment Monitoring, valued at around 1.3 USD Billion in 2024, plays a critical role in assessing therapeutic effectiveness and adjusting strategies promptly. As treatment regimens become more personalized, this segment is vital to enabling healthcare professionals to monitor patients' responses effectively through non-invasive means.

    Recurrence Monitoring is anticipated to hold a value of 0.8 USD Billion in the same year, and it is significant for patients who have undergone cancer treatment, providing essential follow-up insights that can affect long-term survival rates.

    Clinical Trials, also valued at 0.8 USD Billion, contribute significantly by facilitating innovative therapies and ensuring safety while enhancing the drug development process through insights derived from liquid biopsy techniques. Additionally, Research Applications, while smaller with a value of 0.41 USD Billion, are crucial in advancing the understanding of cancer biology and the development of new diagnostic methods, thus laying the groundwork for future breakthroughs.

    Over the years, the importance of these applications has become increasingly clear as they support a wide range of diagnostic and therapeutic advancements. With the Global Liquid Biopsy Market anticipated to expand, these application segments will likely continue to evolve, driving the industry forward and reflecting the shift toward more precise patient care within the healthcare ecosystem.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Liquid Biopsy Market Sample Type Insights

    The Global Liquid Biopsy Market is poised for significant growth, with a projected valuation of 5.51 USD Billion by 2024. This market is essential for non-invasive cancer diagnostics, allowing for real-time monitoring of disease progression and therapeutic responses.

    The market segmentation based on Sample Type includes Blood, Urine, Saliva, Pleural Fluid, and Cerebrospinal Fluid, each contributing uniquely to advancements in medical diagnostics.

    As the market matures, trends indicate increasing adoption of these sample types driven by technological innovations and a growing emphasis on personalized medicine strategies within the Global Liquid Biopsy Market. The industry's growth will continue to be fueled by ongoing Research and Development investments and the rising demand for early-stage cancer diagnostics.

    Liquid Biopsy Market Technology Insights

    The Global Liquid Biopsy Market is seeing robust growth driven by advancements in Technology, with a projected valuation of 5.51 billion USD by 2024 and expected to reach 15.0 billion USD by 2035. This segment encompasses several key technologies that enhance diagnostic capabilities and patient care, with a significant focus on innovations such as Next Generation Sequencing and Digital PCR, which are pivotal for precise cancer profiling and monitoring.

    Furthermore, Microfluidics plays a vital role in enabling efficient sample processing and analysis, while Exosome Isolation techniques are becoming increasingly important for understanding tumor biology and biomarker discovery.

    Circulating Tumor Cells

    Circulating Tumor Cells are at the forefront of research, offering insights into cancer progression and treatment response. The Global Liquid Biopsy Market statistics indicate that this sector not only addresses the growing demand for non-invasive diagnostic solutions but also presents numerous opportunities for personalized medicine, ultimately improving patient outcomes on a global scale. With technology continually evolving, the industry is positioned for significant market growth, paving the way for novel applications in oncology and beyond.

    Liquid Biopsy Market End Use Insights

    The Global Liquid Biopsy Market, particularly in the End Use segment, has shown substantial growth potential, with a market value expected to reach 5.51 billion USD by 2024 and is projected to evolve significantly by 2035. Various applications within this segment, including Hospitals, Diagnostic Laboratories, Research Institutes, and Pharmaceutical Companies, play crucial roles in driving this growth.

    Hospitals are increasingly adopting liquid biopsy procedures for non-invasive testing and early cancer detection, contributing to the overall market expansion. Diagnostic Laboratories are essential for providing specialized testing services which have become more refined with technological advancements.

    Research Institutes are focusing on innovative methodologies to enhance liquid biopsy applications, thereby broadening its utility in precision medicine. Lastly, Pharmaceutical Companies leverage liquid biopsy data for drug development and monitoring treatment responses, highlighting its significance in therapeutic areas.

    Overall, the Global Liquid Biopsy Market segmentation indicates a robust demand driven by the increasing prevalence of cancer, advancements in technology, and the growing need for personalized medicine solutions, placing the industry on a promising growth trajectory.

    Get more detailed insights about Liquid Biopsy Market Research Report - Global Forecast to 2035

    Regional Insights

    The Global Liquid Biopsy Market stands as a noteworthy entity within the healthcare industry, with projections indicating a valuation of 5.51 USD Billion in 2024 and reaching 15.0 USD Billion by 2035. The Regional segment unveils a hierarchy where North America emerges as a dominant player, holding a substantial valuation of 2.5 USD Billion in 2024, expected to grow to 6.8 USD Billion by 2035, thus showcasing its majority holding in the market.

    Europe follows with a valuation of 1.4 USD Billion in 2024, anticipated to expand to 3.8 USD Billion by 2035, indicating its significant role in market growth driven by advanced healthcare infrastructure and high R investment.

    APAC accounts for a valuation of 1.2 USD Billion in 2024, with an eventual rise to 3.3 USD Billion by 2035, supported by increasing cancer prevalence and growing awareness of non-invasive diagnostic options. South America and MEA represent the smaller segments, valued at 0.3 USD Billion and 0.11 USD Billion respectively in 2024, but still providing opportunities due to increasing healthcare investments and rising interest in precision medicine solutions.

    The significant growth in these regions is driven by rising incidences of cancer, technological advancements in liquid biopsy methods, and a focus on personalized medicine, thus enabling the Global Liquid Biopsy Market revenue to flourish across diverse geographical landscapes.

    Liquid Biopsy Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Liquid Biopsy Market has been witnessing significant growth driven by the increasing prevalence of cancer and the rising demand for minimally invasive diagnostic solutions. Liquid biopsy technology enables the detection of cancer biomarkers from blood samples, offering a safe and effective alternative to traditional tissue biopsies.

    This market is characterized by a dynamic competitive landscape, featuring various players vying for market share through innovations in technology, strategic partnerships, and expanding their product offerings. Companies engaged in this space are focusing on developing highly sensitive and specific assays to improve patient outcomes.

    The emergence of personalized medicine and precision health further enhances the relevance of liquid biopsies, increasing competition among market participants who aim to establish their foothold and address the unmet clinical needs of healthcare providers.

    GRAIL

    GRAIL stands out in the Global Liquid Biopsy Market due to its focus on early detection of cancer through innovative blood testing technologies. The company pioneering genomic sequencing methods combined with advanced artificial intelligence algorithms to identify various types of cancers at their earliest stages, which significantly improves patient prognosis and therapy options.

    GRAIL's unique approach to liquid biopsy not only distinguishes it from competitors but also positions it as a leader in the market, with a robust pipeline of ongoing clinical studies validating its flagship products. The company has established strong partnerships with clinical institutions, enhancing its research capabilities and expanding its market presence.

    GRAIL's cutting-edge technology and commitment to advancing liquid biopsy assays reflect its inherent strengths in attaining a commanding position in this evolving industry.

    Natera

    Natera is another key player in the Global Liquid Biopsy Market, focusing on reproductive health and oncology with a strong emphasis on non-invasive testing solutions. The company's core product offerings include theSignatera personalized mRNA tumor antigen assay, which is designed to monitor minimal residual disease and detect recurrences in cancer patients, thereby contributing to better patient management strategies.

    Natera's market presence is bolstered by its advanced laboratory services and a network of partnerships with healthcare providers, which enhance its ability to deliver comprehensive genomic insights. The company has engaged in strategic collaborations and acquisitions to expand its technology platform and enhance its RD capabilities.

    Furthermore, Natera's emphasis on robust clinical validation of its products supports its credibility in the market, empowering it to leverage its strengths in precision medicine as it addresses a growing demand for advanced liquid biopsy solutions on a global scale.

    Key Companies in the Liquid Biopsy Market market include

    Industry Developments

    Recent developments in the Global Liquid Biopsy Market have seen significant advancements, with companies like GRAIL and Exact Sciences pushing innovative technologies and applications. Major players are expanding their portfolios and improving diagnostic capabilities for early cancer detection.

    In September 2023, Natera announced the successful launch of a new assay aimed at enhancing non-invasive prenatal testing, showcasing a potential overlap in liquid biopsy technology. Meanwhile, in August 2023, a collaboration between Foundation Medicine and Roche focused on integrating liquid biopsies into their existing genomic profiling services, emphasizing the increased relevance of these tests in personalized medicine.

    On the mergers and acquisitions front, Thermo Fisher Scientific acquired Brammer Bio in December 2022, with implications for its liquid biopsy capabilities. Growth in market valuation continues to accelerate, attributed to rising collaborations across key companies, including Guardant Health and Illumina, as they enhance product offerings and expand their reach in the oncology segment.

    Significant happenings over the last few years include the establishment of regulatory frameworks facilitating liquid biopsy integration into clinical practices, further confirming their positioning in oncology diagnostics on a global scale.

    Future Outlook

    Liquid Biopsy Market Future Outlook

    The Liquid Biopsy Market is projected to grow at an 8.96% CAGR from 2024 to 2035, driven by advancements in technology, increasing cancer prevalence, and demand for non-invasive diagnostics.

    New opportunities lie in:

    • Develop innovative liquid biopsy assays for early cancer detection.
    • Expand partnerships with healthcare providers to enhance market penetration.
    • Invest in AI-driven analytics for improved data interpretation and patient outcomes.

    By 2035, the Liquid Biopsy Market is expected to achieve substantial growth, reflecting its critical role in personalized medicine.

    Market Segmentation

    Liquid Biopsy Market End Use Outlook

    • Hospitals
    • Diagnostic Laboratories
    • Research Institutes
    • Pharmaceutical Companies

    Liquid Biopsy Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Liquid Biopsy Market Technology Outlook

    • Next Generation Sequencing
    • Digital PCR
    • Microfluidics
    • Exosome Isolation
    • Circulating Tumor Cells

    Liquid Biopsy Market Application Outlook

    • Cancer Diagnosis
    • Treatment Monitoring
    • Recurrence Monitoring
    • Clinical Trials
    • Research Applications

    Liquid Biopsy Market Sample Type Outlook

    • Blood
    • Urine
    • Saliva
    • Pleural Fluid
    • Cerebrospinal Fluid

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2023 8.1 (USD Billion)
    MARKET SIZE 2024 8.9 (USD Billion)
    MARKET SIZE 2035 22.88 (USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 11.60% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Billion
    KEY COMPANIES PROFILED GRAIL, Natera, Foundation Medicine, Exact Sciences, Thermo Fisher Scientific, Avantor, ArcherDX, Roche, Medpace, Illumina, Guardant Health, Qiagen, Freenome, Biocept
    SEGMENTS COVERED Application, Sample Type, Technology, End Use, Regional
    KEY MARKET OPPORTUNITIES Increasing cancer prevalence, Non-invasive diagnostic advancements, Rising demand for personalized medicine, Technological innovations in assays, Expanding applications in clinical trials
    KEY MARKET DYNAMICS increasing cancer prevalence , technological advancements , non-invasive testing preference , regulatory approvals and reimbursement , rising research and development investments
    COUNTRIES COVERED North America, Europe, APAC, South America, MEA

    Market Highlights

    Author
    Kinjoll Dey
    Research Analyst Level I

    He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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    FAQs

    What is the expected market size of the Global Liquid Biopsy Market in 2024?

    The Global Liquid Biopsy Market is expected to be valued at 8.9 USD Billion in 2024.

    What is the projected market size of the Global Liquid Biopsy Market by 2035?

    By 2035, the Global Liquid Biopsy Market is anticipated to reach a valuation of 22.88 USD Billion.

    What is the expected CAGR for the Global Liquid Biopsy Market from 2025 to 2035?

    The expected CAGR for the Global Liquid Biopsy Market from 2025 to 2035 is 0.116%.

    Which region is expected to dominate the Global Liquid Biopsy Market in 2024?

    North America is expected to dominate the Global Liquid Biopsy Market with a value of 2.5 USD Billion in 2024.

    What will be the market size of the Global Liquid Biopsy Market in Europe by 2035?

    The market size for the Global Liquid Biopsy Market in Europe is projected to reach 3.8 USD Billion by 2035.

    What is the forecasted market size for Cancer Diagnosis within the Global Liquid Biopsy Market in 2035?

    The market size for Cancer Diagnosis is expected to reach 5.9 USD Billion in 2035.

    Who are some of the major players in the Global Liquid Biopsy Market?

    Major players in the Global Liquid Biopsy Market include GRAIL, Natera, Foundation Medicine, and Thermo Fisher Scientific.

    What is the anticipated market size for Treatment Monitoring in 2024?

    The anticipated market size for Treatment Monitoring in 2024 is 1.3 USD Billion.

    What is the projected growth of the Global Liquid Biopsy Market in the Asia-Pacific region by 2035?

    The Asia-Pacific region is projected to grow to a market size of 3.3 USD Billion by 2035.

    What is the market size for Recurrence Monitoring within the Global Liquid Biopsy Market in 2024?

    The market size for Recurrence Monitoring is valued at 0.8 USD Billion in 2024.

    Liquid Biopsy Market Research Report - Global Forecast to 2035 Infographic
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