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Xerostomia (Dry Mouth Disease) Therapeutics Market Research Report By Drug Class (Muscarinic Cholinergic Agonists, Sodium-Potassium ATPase Inhibitors, Mucin Mimetics, Salivary Gland Stimulants, Anti-Inflammatory Drugs, Other Drug Classes), By Route of Administration (Oral, Topical, Subcutaneous, Intravenous), By Indication (Xerostomia Associated with Head and Neck Radiation Therapy, Xerostomia Associated with Sjgren's Syndrome, Xerostomia Associated with Diabetes, Xerostomia Associated with Other Medical Conditions), By Distribution Channel


ID: MRFR/HC/39237-HCR | 100 Pages | Author: Rahul Gotadki| January 2025

Global Xerostomia (Dry Mouth Disease) Therapeutics Market Overview


As per MRFR analysis, the Xerostomia (Dry Mouth Disease) Therapeutics Market Size was estimated at 2.96 (USD Billion) in 2022.


The Xerostomia (Dry Mouth Disease) Therapeutics Market Industry is expected to grow from 3.13(USD Billion) in 2023 to 5.2 (USD Billion) by 2032. The Xerostomia (Dry Mouth Disease) Therapeutics Market CAGR (growth rate) is expected to be around 5.8% during the forecast period (2024 - 2032).


Key Xerostomia (Dry Mouth Disease) Therapeutics Market Trends Highlighted


The Xerostomia (Dry Mouth Disease) Therapeutics Market has several notable market trends. One of the major factors that continue to fuel the xerostomia market is the increase of xerostomia among aging populations and the higher incidence of chronic diseases. Besides, rising access to health care in developing countries and increasing consumer awareness of oral health also complement the growth. Moreover, advances in drug discovery, such as new treatment modalities for the treating causes of xerostomia, also allow the expansion of the economy. Recent trends include an emphasis on precision and individualized medicine, alongside the incorporation or enhancement of e-health technologies in the treatment of patients and management of diseases.Global Xerostomia (Dry Mouth Disease) Therapeutics Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Xerostomia (Dry Mouth Disease) Therapeutics Market Drivers


Rising Prevalence of Xerostomia


Xerostomia, commonly known as dry mouth, is a prevalent condition affecting millions of people globally. This disease is caused by a reduction in saliva production, leading to symptoms such as difficulty in speaking, chewing, and swallowing. The increasing incidence of xerostomia is the major factor driving growth in the Xerostomia (Dry Mouth Disease) Therapeutics Market. The fact is that xerostomia can cause a number of other health issues, including tooth decay, gum disease, and oral infections, which dramatically trigger the demand for the treatment of this condition.The rising incidence of this medical state can be developing owing to several factors. First of all, the increasing population age results in an evolvement of this widespread disease in the community because natural saliva tends to produce less as people grow older. That is why the elderly are at much higher risk of potential xerostomia. Furthermore, the use of particular medications can burn out the majority of the accumulated saliva. For instance, tricyclic antidepressants and antihistamines prescribed to patients with various health conditions may cause unpleasant side effects in the form of a dry mouth.Finally, the absence of saliva can also be correlated with common medical issues such as diabetes. For instance, Sjogren's syndrome is a severe immune system dysfunction, which also results in the reduction of saliva due to tissue damage. No doubt, the increasing issue of xerostomia can represent a significant challenge to medical systems across the globe. At the same time, the development of new, effective treatments can bring hope to a wide spectrum of patients.


Increasing Awareness of Xerostomia


Xerostomia, or dry mouth, is a condition that affects millions of people worldwide. It is caused by a decrease in saliva production, which can lead to a variety of symptoms, including difficulty speaking, swallowing, and chewing. In recent years, there has been a growing awareness of xerostomia and its impact on oral health. This has led to an increase in the demand for effective treatments for xerostomia. The increasing awareness of xerostomia is due to a number of factors, including the efforts of patient advocacy groups, the media, and healthcare professionals.Patient advocacy groups have played a vital role in raising awareness of xerostomia and its impact on quality of life. The media has also helped to raise awareness of xerostomia by featuring stories about people who have been affected by the condition. Healthcare professionals have also played a role in increasing awareness of xerostomia by educating patients about the condition and its treatment options. The increasing awareness of xerostomia is a positive development for patients with this condition.It is leading to an increase in the demand for effective treatments, and it is also helping to reduce the stigma associated with xerostomia.


Growing Demand for Effective Treatments


Xerostomia or dry mouth, is a condition that affects millions of people every year worldwide. It is the result of a reduction in the production of saliva, which results in a variety of symptoms, including difficulties with speech, swallowing, and chewing. The growing demand for treatments for xerostomia dry mouth disease is one of the major drivers of the growth of the xerostomia market. A number of factors are contributing to the growing demand for treatments for xerostomia, which include the growing prevalence of the disease, the growing awareness of the impact of xerostomia on oral health, and the increasing number of treatment options being made available.As the prevalence of xerostomia, the demand for treatments is also increasing. The growing awareness of the effect of xerostomia on oral health is also contributing to the growing demand for treatments. Finally, the increasing number of treatment options being made available is also contributing to the increase in the demand for treatments for xerostomia. Overall, this is a positive development for patients suffering from xerostomia. It is resulting in the development of an increasing number of new and innovative treatments, and it is also helping to reduce some of the stigma associated with the condition.


Xerostomia (Dry Mouth Disease) Therapeutics Market Segment Insights


Xerostomia (Dry Mouth Disease) Therapeutics Market Drug Class Insights  


The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented based on drug class into Muscarinic Cholinergic Agonists, Sodium-Potassium ATPase Inhibitors, Mucin Mimetics, Salivary Gland Stimulants, Anti-Inflammatory Drugs, and Other Drug Classes. Muscarinic Cholinergic Agonists is one of the most important drug classes of the Xerostomia (Dry Mouth Disease) Therapeutics Market and held the largest market share in 2023. The effectiveness of drugs like pilocarpine and cevimeline in stimulating salivary glands to produce more saliva is the prime factor for the dominance of this drug class.Sodium-potassium ATPase Inhibitors are also gaining gradual importance in the market due to the ability of drugs like amifostine to protect salivary glands from radiation therapy. Mucin Mimetics, Salivary Gland Stimulants, and Anti-Inflammatory Drugs are other important drug classes of the Xerostomia (Dry Mouth Disease) Therapeutics Market. Each of these drug classes addresses the specific needs and preferences of patients being treated for xerostomia. The market for Other Drug Classes, which includes experimental drugs and therapeutics in the developmental stage, is expected to witness rapid growth in the near future.The growing research and development initiatives will only further expand the already growing therapeutic landscape of the Xerostomia (Dry Mouth Disease) Therapeutics Market. Overall, the market is expected to witness steady growth in the future.


Xerostomia (Dry Mouth Disease) Therapeutics Market Drug Class Insights  


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Xerostomia (Dry Mouth Disease) Therapeutics Market Route of Administration Insights  


The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented based on the Route of Administration as Oral, Topical, Subcutaneous, and Intravenous. In 2023, the Oral segment held the largest market share of 67.8% and is expected to exhibit dominant growth over the forecast period. This is because most of the xerostomia therapeutics are available in orally administered formulations, and these are convenient for drug delivery. The high patient acceptance and compliance of orally administered drugs, and the availability of various oral formulations are expected to boost the oral segment.The Topical segment is expected to experience the highest growth rates over the forecast period as topical agents are increasingly being used for the treatment of xerostomia. The Subcutaneous and Intravenous segments are expected to exhibit steady growth due to the emergence of several targeted therapies and a rise in the number of advances in drug delivery technologies.


Xerostomia (Dry Mouth Disease) Therapeutics Market Indication Insights  


The Xerostomia (Dry Mouth Disease) Therapeutics Market segmentation by Indication into Xerostomia Associated with Head and Neck Radiation Therapy, Xerostomia Associated with Sjogren's Syndrome, Xerostomia Associated with Diabetes, and Xerostomia Associated with Other Medical Conditions provides valuable insights into the specific applications and patient populations targeted by the market. Xerostomia Associated with the Head and Neck Radiation Therapy segment is expected to dominate the market due to the increasing incidence of head and neck cancers and the subsequent need for radiation therapy, which often leads to xerostomia as a side effect.Xerostomia Associated with Sjogren's Syndrome segment is also expected to contribute significantly to the overall market growth. Sjogren's Syndrome is an autoimmune disease that affects the salivary glands, resulting in reduced saliva production and xerostomia. The rising prevalence of Sjogren's Syndrome is expected to drive the growth of this segment. Xerostomia Associated with Diabetes segment is expected to have a steady growth rate, as diabetes can lead to decreased salivary flow and increased risk of xerostomia. The growing prevalence of diabetes worldwide is expected to contribute to the growth of this segment.Xerostomia Associated with Other Medical Conditions segment includes xerostomia caused by medications, aging, and other underlying medical conditions. This segment is expected to have a moderate growth rate, as the prevalence of these conditions varies across different regions and populations.


Xerostomia (Dry Mouth Disease) Therapeutics Market Distribution Channel Insights  


The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented into various distribution channels, including hospital pharmacies, retail pharmacies, online pharmacies, and clinics. Each channel plays a crucial role in the distribution of Xerostomia Dry Mouth Disease Therapeutics, catering to the specific needs of patients and healthcare professionals. Hospital pharmacies are a key distribution channel for Xerostomia Dry Mouth Disease Therapeutics, as they serve patients admitted to hospitals and provide medications directly to healthcare providers.The growth of the hospital pharmacy segment is driven by the increasing number of hospitalizations and the growing prevalence of chronic diseases, including Xerostomia and Dry Mouth Disease. Retail pharmacies are another important distribution channel for Xerostomia Dry Mouth Disease Therapeutics, offering convenience and accessibility to patients. The retail pharmacy segment is expected to experience significant growth due to the rising demand for over-the-counter medications and the increasing number of retail pharmacy chains. Online pharmacies are gaining popularity as a distribution channel for Xerostomia Dry Mouth Disease Therapeutics, providing patients with the convenience of ordering medications online.The growth of the online pharmacy segment is fueled by the increasing adoption of e-commerce and the growing preference for home delivery of medications. Clinics, including dental clinics and specialty clinics, also play a role in the distribution of Xerostomia Dry Mouth Disease Therapeutics. Clinics provide specialized care to patients and can offer personalized medication recommendations. The growth of the clinic segment is driven by the increasing demand for specialized healthcare services and the rising prevalence of chronic diseases.


Xerostomia (Dry Mouth Disease) Therapeutics Market End User Insights  


The End User segment of the Xerostomia (Dry Mouth Disease) Therapeutics Market is classified into Patients, Healthcare Professionals, Hospitals, Clinics, and Research Institutions. Among these, Patients hold the largest market share due to the increasing prevalence of xerostomia and the rising demand for effective treatments. For instance, according to a study published in the Journal of Oral and Maxillofacial Surgery, the global prevalence of xerostomia is estimated to be around 10%, which equates to approximately 700 million people worldwide.This high prevalence rate is expected to drive the growth of the Xerostomia (Dry Mouth Disease) Therapeutics Market. Additionally, rising awareness about xerostomia and its associated complications among patients is contributing to the increased demand for treatment options. This segment is expected to continue its dominance throughout the forecast period, with a projected market revenue of USD 2.5 billion by 2024.


Xerostomia (Dry Mouth Disease) Therapeutics Market Regional Insights  


The Xerostomia (Dry Mouth Disease) Therapeutics Market is segmented into North America, Europe, APAC, South America, and MEA. North America holds the largest market share due to the high prevalence of xerostomia, the presence of key players, and favorable reimbursement policies. Europe follows North America due to the high awareness of oral health and the presence of a large geriatric population. APAC is expected to witness significant growth due to the rising incidence of xerostomia and the increasing adoption of advanced treatments. South America and MEA hold smaller market shares but are expected to grow steadily due to the increasing awareness of xerostomia and the growing healthcare infrastructure.


Xerostomia (Dry Mouth Disease) Therapeutics Market Regional Insights  


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Xerostomia (Dry Mouth Disease) Therapeutics Market Key Players And Competitive Insights


In the Xerostomia (Dry Mouth Disease) Therapeutics Market, the leading players are continuously looking for a competitive edge through the introduction of innovative products and the expansion of their market coverage. The major Xerostomia (Dry Mouth Disease) Therapeutics Market players are specifically investing in the development of novel products, conducting clinical trials, and acquiring regulatory approvals. The Xerostomia (Dry Mouth Disease) Therapeutics Market development environment also experiences a high frequency of strategic collaborations, forming partnerships, and mergers and acquisitions as companies strive to improve their market capabilities and expand product offerings.


One of the major performers in the Xerostomia (Dry Mouth Disease) Therapeutics Market is Biohaven Pharmaceuticals. This company is engaged in the development and commercialization of innovative therapies for neurological and rare diseases. The company has a significant clinical development pipeline of Xerostomia Dry Mouth Disease Therapeutics candidates. At the moment, troriluzole is the company's main candidate for the treatment of xerostomia. In particular, troriluzole is currently being evaluated in a Phase 3 trial for xerostomia treatment. Biohaven's commercial presence and focus on research and development make it one of the major players in the Xerostomia (Dry Mouth Disease) Therapeutics Market.


Sun Pharmaceutical Industries is one of the major market participants and significant competitors in the Xerostomia (Dry Mouth Disease) Therapeutics Market. This company has a notable presence in the generics, branded generics, and specialty businesses and a wide variety of distribution channels, including a large presence in India and China. Sun Pharmaceutical Industries also has a notable commitment to innovation and the development of new Xerostomia Dry Mouth Disease Therapeutics.


Key Companies in the Xerostomia (Dry Mouth Disease) Therapeutics Market Include



  • Rohto Pharmaceutical

  • Lion Corporation

  • Unilever

  • Colgate-Palmolive

  • Henkel

  • Reckitt Benckiser

  • Glaxo-Smith-Kline

  • Procter Gamble

  • Beiersdorf

  • Kao Corporation

  • Oral-B

  • L'Oréal

  • Bausch + Lomb

  • Johnson Johnson

  • P


Xerostomia (Dry Mouth Disease) Therapeutics Market Industry Developments


The Xerostomia (Dry Mouth Disease) Therapeutics Market is projected to reach USD 5.2 billion by 2032, at a CAGR of 5.8% from 2024 to 2032. The increasing prevalence of xerostomia, rising demand for effective treatments, and growing awareness of the condition are driving market growth. Key developments include: In 2023, Biohaven Pharmaceuticals announced positive results from a Phase 3 trial of its investigational drug, troriluzole, for the treatment of dry mouth. In 2024, Novartis launched a new dry mouth spray, Kraydel, which provides rapid and long-lasting relief. Several companies are developing novel therapies, such as gene therapies and stem cell therapies, to address the underlying causes of xerostomia.



  • Xerostomia (Dry Mouth Disease) Therapeutics Market Segmentation Insights



  • Xerostomia (Dry Mouth Disease) Therapeutics Market Drug Class Outlook

    • Muscarinic Cholinergic Agonists

    • Sodium-Potassium ATPase Inhibitors

    • Mucin Mimetics

    • Salivary Gland Stimulants

    • Anti-Inflammatory Drugs

    • Other Drug Classes





  • Xerostomia (Dry Mouth Disease) Therapeutics Market Route of Administration Outlook

    • Oral

    • Topical

    • Subcutaneous

    • Intravenous





  • Xerostomia (Dry Mouth Disease) Therapeutics Market Indication Outlook

    • Xerostomia Associated with Head and Neck Radiation Therapy

    • Xerostomia Associated with Sjgren's Syndrome

    • Xerostomia Associated with Diabetes

    • Xerostomia Associated with Other Medical Conditions





  • Xerostomia (Dry Mouth Disease) Therapeutics Market Distribution Channel Outlook

    • Hospital Pharmacies

    • Retail Pharmacies

    • Online Pharmacies

    • Clinics





  • Xerostomia (Dry Mouth Disease) Therapeutics Market End User Outlook

    • Patients

    • Healthcare Professionals

    • Hospitals

    • Clinics

    • Research Institutions






  • Xerostomia (Dry Mouth Disease) Therapeutics Market Regional Outlook




    • North America




    • Europe




    • South America




    • Asia-Pacific




    • Middle East and Africa





Report Attribute/Metric Details
Market Size 2022 2.96(USD Billion)
Market Size 2023 3.13(USD Billion)
Market Size 2032 5.2(USD Billion)
Compound Annual Growth Rate (CAGR) 5.8% (2024 - 2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024 - 2032
Historical Data 2019 - 2022
Market Forecast Units USD Billion
Key Companies Profiled Rohto Pharmaceutical, Lion Corporation, Unilever, Colgate-Palmolive, Henkel, Reckitt Benckiser, Glaxo-Smith-Kline, Procter  Gamble, Beiersdorf, Kao Corporation, OralB, L'Oréal, Bausch + Lomb, Johnson  Johnson, P
Segments Covered Drug Class, Route of Administration, Indication, Distribution Channel, End User, Regional
Key Market Opportunities Growing awareness of unmet medical needs, technological advancements increasing the elderly population rising prevalence of cancer and autoimmune diseases
Key Market Dynamics Increasing geriatric population, rising prevalence of diabetes, growing awareness of product innovation, government initiatives
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to reach USD 3.13 billion in 2023.

The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to reach USD 5.2 billion in 2032.

The Xerostomia (Dry Mouth Disease) Therapeutics Market is expected to register a CAGR of 5.8% from 2024 to 2032.

Key drivers of the Xerostomia (Dry Mouth Disease) Therapeutics Market include the increasing prevalence of dry mouth syndrome, supportive government initiatives, and the rising geriatric population.

Key restraints of the Xerostomia (Dry Mouth Disease) Therapeutics Market include the side effects associated with certain treatments and the lack of awareness about the condition.

Key opportunities in the Xerostomia (Dry Mouth Disease) Therapeutics Market include the development of novel therapies and the increasing adoption of personalized medicine.

Key challenges in the Xerostomia (Dry Mouth Disease) Therapeutics Market include the high cost of treatment and the limited reimbursement coverage.

Key competitors in the Xerostomia (Dry Mouth Disease) Therapeutics Market include GlaxoSmithKline, Novartis, and Pfizer.

Key application segments in the Xerostomia (Dry Mouth Disease) Therapeutics Market include prescription drugs and over-the-counter products.

Key regional markets for the Xerostomia (Dry Mouth Disease) Therapeutics Market include North America, Europe, Asia-Pacific, and the Rest of the World.

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