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    US 3D Cell Culture Market

    ID: MRFR/LS/13112-HCR
    128 Pages
    Garvit Vyas
    September 2025

    United States 3D Cell Culture Market Research Report Information By Product (Scaffold-based 3D Cell Cultures, Scaffold-free 3D Cell Cultures, Microfluidics-based 3D Cell Cultures, and Magnetic & Bioprinted 3D Cell Cultures), By Application (Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine), By End User (Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetics Industry, and Other End Users), - United States Market Forecast Till 2034

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    Table of Contents

    US 3D Cell Culture Market Summary

    The United States 3D Cell Culture market is projected to grow from 0.85 USD Billion in 2024 to 3.12 USD Billion by 2035, reflecting a robust CAGR of 12.54%.

    Key Market Trends & Highlights

    US 3D Cell Culture Key Trends and Highlights

    • The market valuation is expected to reach 3.12 USD Billion by 2035, indicating substantial growth potential.
    • From 2025 to 2035, the market is anticipated to expand at a compound annual growth rate of 12.54%.
    • In 2024, the market is valued at 0.85 USD Billion, laying a strong foundation for future growth.
    • Growing adoption of 3D cell culture technologies due to increasing research and development activities is a major market driver.

    Market Size & Forecast

    2024 Market Size 0.85 (USD Billion)
    2035 Market Size 3.12 (USD Billion)
    CAGR (2025-2035) 12.54%

    Major Players

    Thermo Fisher Scientific, Inc., Lonza, Corning Incorporated, Avantor Inc., Merck KGaA

    US 3D Cell Culture Market Trends

    • Growth in Cancer Research Funding and Investments to Boost the Market Growth

    Research on 3D cell culture technology has become increasingly important, especially in the field of tumor cell biology, which is driving the market CAGR. To generate three-dimensional (3D) cell culture models that replicate the in-vivo environment of grown tumor cells, researchers employ a range of procedures and materials. Because 3D cell culture replicates the complicated tumor microenvironment, it aids researchers in understanding the biological characteristics of tumor cells.

    US 3D Cell Culture Market Drivers

    Market Segment Insights

    3D Cell Culture Product Insights

    The United States 3D Cell Culture market segmentation, based on product, includes Scaffold-based 3D Cell Cultures, Scaffold-free 3D Cell Cultures, Microfluidics-based 3D Cell Cultures, and Magnetic & Bioprinted 3D Cell Cultures. The scaffold-based 3D cell cultures segment dominated the market mostly. The market is anticipated to develop as a consequence of things like the expanding uses of scaffold-based cultures in tissue engineering and regenerative medicine, advancements in scaffold materials and manufacturing techniques, and more financing and cooperation for research. The segment is expected to grow as a result of recent product releases, ongoing research initiatives, and technology advances.

    3D Cell Culture Application Insights

    The United States 3D Cell Culture market segmentation, based on application, includes Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine. The cancer & stem cell research category generated the most income. The main drivers of the segment's growth are the rising demand for biopharmaceuticals as a result of successful therapies like gene and cell therapy and the surge in innovation that led to more approvals.

    Based on the current clinical success rates and the product pipeline, the United States FDA is anticipated to approve 10 to 20 cell and gene therapy medicines annually by 2025. 

    Figure 1: United States 3D Cell Culture Market, by Application, 2023 & 2032 (USD Billion)

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    3D Cell Culture End User Insights

    The United States 3D Cell Culture market segmentation, based on end user, includes Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetics Industry, and Other End Users. The pharmaceutical & biotechnology companies category generated the most income. The expansion of the segment has been attributed to the biopharmaceuticals' ongoing development and commercial success, as well as their ability to leverage the portfolios of large pharmaceutical companies. Compared to two-dimensional cellular media, a three-dimensional model has advantages such as excellent oxygen and nutrient gradient generation and realistic cellular interactions for drug research. 

    3D Cell Culture Country Insights

    The existence of developed economies, sophisticated healthcare infrastructure, major players, and their different strategic initiatives are the factors that collectively drive the United States 3D cell culture market. Furthermore, it is anticipated that a multitude of research institutions and colleges exploring various stem-cell-based methodologies, along with a government that supports the creation of three-dimensional culture models and an accommodating regulatory environment, will maintain the regional market. In April 2023, for instance, the American Cancer Society (ACS) declared that 90 innovative Extramural Discovery Science (EDS) projects at 67 institutions around the country will receive funding totaling more than USD 45 million.

    Moreover, the United States is witnessing a surge in 3D cell culture owing to multiple variables such as technological progress, growing researcher acceptance, expanding applications across multiple fields, and market leaders' growth activities. For instance, in May 2021, CELLINK, a bio convergence startup, purchased Visikol Corp.. This U.S.-based contract research services provider provides industry-leading services in digital pathology, multiplex imaging, 3D tissue imaging, and 3D cell culture to pharmaceutical and biotech businesses. 

    Get more detailed insights about US 3d Cell Culture Market Research Report - Forecast Till 2034

    Regional Insights

    Key Players and Competitive Insights

    Leading market players are investing heavily in research and development in order to expand their product lines, which will help the 3D cell culture market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, 3D cell culture industry must offer cost-effective items.

    Major players in the 3D cell culture market are attempting to increase market demand by investing in research and development operations, including Thermo Fisher Scientific, Inc. (US), Lonza (Switzerland), Corning Incorporated (US), Avantor Inc. (US), Merck KGaA (Germany), and others.

    Key Companies in the US 3D Cell Culture Market market include

    Industry Developments

    June 2023: The private research university Stanford University in California, the United States, and Sartorius, a global supplier of pharmaceuticals and laboratory equipment, expanded their partnership to create a scalable platform for the large-scale manufacturing of humaniPSCs.

    October 2022: With the Elplasia 12K flask, Corning established a novel microcavity geometry that streamlines the processes of spheroid formation, culture, treatment, evaluation, and harvesting. A 125-fold higher yield than conventional 96-well spheroid plates is achieved by the flask, which generates about 12,000 spheroids of uniform size and shape per flask.

    Market Segmentation

    3D Cell Culture Product Outlook

    • Scaffold-based 3D Cell Cultures
    • Scaffold-free 3D Cell Cultures
    • Microfluidics-based 3D Cell Cultures
    • Magnetic & Bioprinted 3D Cell Cultures

    3D Cell Culture End User Outlook

    • Pharmaceutical & Biotechnology Companies
    • Research Institutes
    • Cosmetics Industry
    • Other End Users

    3D Cell Culture Application Outlook

    • Cancer & Stem Cell Research
    • Drug Discovery & Toxicology Testing
    • Tissue Engineering & Regenerative Medicine

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024    0.85 (USD Billion)
    Market Size 2025    0.96 (USD Billion)
    Market Size 2034    2.77 (USD Billion)
    Compound Annual Growth Rate (CAGR)   12.50 % (2025 - 2034)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2034
    Historical Data 2020 - 2024
    Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
    Segments Covered Product, Application, End User, and Region
    Countries Covered United States
    Key Companies Profiled Thermo Fisher Scientific, Inc. (US), Lonza (Switzerland), Corning Incorporated (US), Avantor Inc. (US), Merck KGaA (Germany), and others
    Key Market Opportunities Rise in 3D cell culture research and development
    Key Market Dynamics Growing number of major corporations launching products Increasing rates of infectious illnesses and cancer

    Market Highlights

    Author
    Garvit Vyas
    Analyst

    Explore the profile of Garvit Vyas, one of our esteemed authors at Market Research Future, and access their expert research contributions in the field of market research and industry analysis

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    FAQs

    How much is the 3D cell culture market?

    The United States 3D Cell Culture market size was valued at USD 0.85 Billion in 2024.

    What is the growth rate of the 3D cell culture market?

    The market is projected to grow at a CAGR of 12.50% during the forecast period, 2025-2034.

    Who are the key players in the 3D cell culture market?

    The key players in the market are Thermo Fisher Scientific, Inc. (US), Lonza (Switzerland), Corning Incorporated (US), Avantor Inc. (US), Merck KGaA (Germany), and others.

    Which product led the 3D cell culture market?

    The Scaffold-based 3D Cell Cultures category dominated the market in 2024.

    Which application had the largest market share in the 3D cell culture market?

    The Cancer & Stem Cell Research category had the largest share in the market.

    What is the projected market size of the US 3D Cell Culture Market by 2035?

    By 2035, the US 3D Cell Culture Market is expected to reach a valuation of 2240.0 USD Million.

    What was the market size of the US 3D Cell Culture Market in 2024?

    In 2024, the market size of the US 3D Cell Culture Market is estimated to be 730.8 USD Million.

    What is the expected CAGR for the US 3D Cell Culture Market from 2025 to 2035?

    The expected CAGR for the US 3D Cell Culture Market from 2025 to 2035 is 10.719%.

    Which application segment holds the largest market share in the US 3D Cell Culture Market?

    The Drug Discovery application segment is projected to hold the largest market share, valued at 800.0 USD Million by 2035.

    Who are the key players in the US 3D Cell Culture Market?

    Major players in the US 3D Cell Culture Market include InSphero, Intellipath, Lonza, ReproCELL, and Thermo Fisher Scientific.

    What is the market size for Toxicology Testing within the US 3D Cell Culture Market by 2035?

    The Toxicology Testing segment is expected to reach a market size of 560.0 USD Million by 2035.

    What are the expected growth opportunities in the US 3D Cell Culture Market?

    The market is expected to grow significantly due to advancements in drug development and increasing demand for effective therapies.

    What is the market value of Regenerative Medicine in the US 3D Cell Culture Market by 2024?

    Regenerative Medicine is expected to have a market value of 150.8 USD Million in 2024.

    What is the projected value of Cancer Research in the US 3D Cell Culture Market by 2035?

    By 2035, the Cancer Research segment is anticipated to reach a market value of 400.0 USD Million.

    How will the US 3D Cell Culture Market evolve through 2035?

    The US 3D Cell Culture Market is poised for substantial growth driven by technological innovations and increasing research funding.

    1. EXECUTIVE SUMMARY
    2. MARKET INTRODUCTION
      1. Definition
      2. Scope of the Study
        1. Research Objective
        2. Assumptions
        3. Limitations
    3. RESEARCH METHODOLOGY
      1. Overview
      2. Data Mining
      3. Secondary Research
      4. Primary Research
        1. Primary Interviews and Information Gathering Process
        2. Breakdown of Primary Respondents
      5. Forecasting Model
      6. Market Size Estimation
        1. Bottom-Up Approach
        2. Top-Down Approach
      7. Data Triangulation
      8. Validation
    4. MARKET DYNAMICS
      1. Overview
      2. Drivers
      3. Restraints
      4. Opportunities
    5. MARKET FACTOR ANALYSIS
      1. Value Chain Analysis
      2. Porter’s Five Forces Analysis
        1. Bargaining Power of Suppliers
        2. Bargaining Power of Buyers
        3. Threat of New Entrants
        4. Threat of Substitutes
        5. Intensity of Rivalry
      3. COVID-19 Impact Analysis 
        1. Market Impact Analysis
        2. Regional Impact
        3. Opportunity and Threat Analysis
    6. UNITED STATES 3D CELL CULTURE MARKET, BY PRODUCT
      1. Overview
      2. Scaffold-based 3D Cell Cultures
      3. Scaffold-free 3D Cell Cultures
      4. Microfluidics-based 3D Cell Cultures 
      5. Magnetic & Bioprinted 3D Cell Cultures
    7. UNITED STATES 3D CELL CULTURE MARKET, BY APPLICATION
      1. Overview
      2. Cancer & Stem Cell Research
      3. Drug Discovery & Toxicology Testing
      4. Tissue Engineering & Regenerative Medicine
    8. UNITED STATES 3D CELL CULTURE MARKET, BY END USER
      1. Overview
      2. Pharmaceutical & Biotechnology Companies
      3. Research Institutes
      4. Cosmetics Industry
      5. Other End Users
    9. COMPETITIVE LANDSCAPE
      1. Overview
      2. Competitive Analysis
      3. Market Share Analysis
      4. Major Growth Strategy in the United States 3D Cell Culture Market,
      5. Competitive Benchmarking
      6. Leading Players in Terms of Number of Developments in the United States 3D Cell Culture Market,
      7. Key developments and Growth Strategies
        1. New Product Launch/Service Deployment
        2. Merger & Acquisitions
        3. Joint Ventures
      8. Major Players Financial Matrix 
        1. Sales & Operating Income, 2023
        2. Major Players R&D Expenditure. 2023
    10. COMPANY PROFILES
      1. Thermo Fisher Scientific, Inc. (US)
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      2. LONZA (SWITZERLAND)
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      3. Corning Incorporated (US)
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      4. Avantor Inc. (US)
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
      5. Merck KGaA (Germany)
        1. Company Overview
        2. Financial Overview
        3. Products Offered
        4. Key Developments
        5. SWOT Analysis
        6. Key Strategies
    11. APPENDIX
      1. References
      2. Related Reports

    US 3d Cell Culture Market Segmentation

    Market Segmentation Overview

    • Detailed segmentation data will be available in the full report
    • Comprehensive analysis by multiple parameters
    • Regional and country-level breakdowns
    • Market size forecasts by segment
    Report Infographic
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