United States 3D Cell Culture Market Research Report Information By Product (Scaffold-based 3D Cell Cultures, Scaffold-free 3D Cell Cultures, Microfluidics-based 3D Cell Cultures, and Magnetic & Bioprinted 3D Cell Cultures), By Application (Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine), By End User (Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetics Industry, and Other End Users), - United States Market Forecast Till 2032

US 3D Cell Culture Market Overview

United States 3D Cell Culture Market Size was valued at USD 0.6 Billion in 2022. The 3D cell culture market industry is projected to grow from USD 0.7 Billion in 2023 to USD 1.8 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 12.50% during the forecast period (2024 - 2032).The United States 3D Cell Cultureindustry is expected to rise as a result of increased efforts to create viable substitutes for animal testing as well as the availability of funding programs for research. In addition, persistent efforts in research and development (R&D) by biopharmaceutical companies for drug discovery and development, along with a focus on the use of 3D cell cultures in cancer research, are key market drivers expected to drive market expansion throughout the estimated period. 

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

3D Cell Culture Market Trends

• Growth in Cancer Research Funding and Investments to Boost the Market Growth

Research on 3D cell culture technology has become increasingly important, especially in the field of tumor cell biology, which is driving the market CAGR. To generate three-dimensional (3D) cell culture models that replicate the in-vivo environment of grown tumor cells, researchers employ a range of procedures and materials. Because 3D cell culture replicates the complicated tumor microenvironment, it aids researchers in understanding the biological characteristics of tumor cells. In addition, it allows researchers to examine changes in cell shape, proliferation, and gene expression, as well as to provide insights into the biological properties of tumor cells and mimic the tumor microenvironment and phenotypic heterogeneity. Additionally, a number of governmental and private organizations are concentrating on investing in and providing funds to advance cancer research. For instance, the Cancer Prevention and Research Institute of Texas (CPRIT) (United States) governing committee approved the allocation of approximately $90 million for research hubs across Texas to support cancer research in February 2023. Similarly, the United States government awarded $50 million to West Virginia University Health Sciences Center (United States) in June 2023 to support the expansion of cancer research and treatments. Therefore, it is anticipated that growing public-private funding and investments in cancer research will propel the 3D cell culture market.

The large-scale automated cell culture system’s development, the growing need for organ transplantation, and the usage of 3D cell culture models as substitutes for in vivo testing are some of the reasons driving the stable growth of the 3D cell culture market. In addition to enabling drug safety and efficacy assessment in a more in vivo-like setting than traditional 2D cell cultures, 3D cell culture and co-culture models also have the potential to eliminate species differences that could limit the interpretation of preclinical outcomes by allowing drug testing in human systems directly. These advantages are enormous. Furthermore, as the need for organ transplants grows, 3D cell cultures will probably also become more and more necessary since intricate features of human physiology, pathology, and medication reactions need to be replicated in vitro. As per the United States Health Resources and Services Administration's organdonor.gov website, as of October 2021, there were 107,103 people waiting for organ transplants nationwide in 2020. As a result, there is a growing need for research models that employ 3D cell cultures due to the rise in organ transplants. Thus, driving the 3D cell culture market revenue.

3D Cell Culture Market Segment Insights

3D Cell Culture Product Insights

The United States 3D Cell Culture market segmentation, based on product, includes Scaffold-based 3D Cell Cultures, Scaffold-free 3D Cell Cultures, Microfluidics-based 3D Cell Cultures, and Magnetic & Bioprinted 3D Cell Cultures. The scaffold-based 3D cell cultures segment dominated the market mostly. The market is anticipated to develop as a consequence of things like the expanding uses of scaffold-based cultures in tissue engineering and regenerative medicine, advancements in scaffold materials and manufacturing techniques, and more financing and cooperation for research. The segment is expected to grow as a result of recent product releases, ongoing research initiatives, and technology advances.

3D Cell Culture Application Insights

The United States 3D Cell Culture market segmentation, based on application, includes Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing, and Tissue Engineering & Regenerative Medicine. The cancer & stem cell research category generated the most income. The main drivers of the segment's growth are the rising demand for biopharmaceuticals as a result of successful therapies like gene and cell therapy and the surge in innovation that led to more approvals. Based on the current clinical success rates and the product pipeline, the United States FDA is anticipated to approve 10 to 20 cell and gene therapy medicines annually by 2025. 

Figure 1: United States 3D Cell Culture Market, by Application, 2023 & 2032 (USD Billion)

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

3D Cell Culture End User Insights

The United States 3D Cell Culture market segmentation, based on end user, includes Pharmaceutical & Biotechnology Companies, Research Institutes, Cosmetics Industry, and Other End Users. The pharmaceutical & biotechnology companies category generated the most income. The expansion of the segment has been attributed to the biopharmaceuticals' ongoing development and commercial success, as well as their ability to leverage the portfolios of large pharmaceutical companies. Compared to two-dimensional cellular media, a three-dimensional model has advantages such as excellent oxygen and nutrient gradient generation and realistic cellular interactions for drug research. 

3D Cell Culture Country Insights

The existence of developed economies, sophisticated healthcare infrastructure, major players, and their different strategic initiatives are the factors that collectively drive the United States 3D cell culture market. Furthermore, it is anticipated that a multitude of research institutions and colleges exploring various stem-cell-based methodologies, along with a government that supports the creation of three-dimensional culture models and an accommodating regulatory environment, will maintain the regional market. In April 2023, for instance, the American Cancer Society (ACS) declared that 90 innovative Extramural Discovery Science (EDS) projects at 67 institutions around the country will receive funding totaling more than USD 45 million. Moreover, the United States is witnessing a surge in 3D cell culture owing to multiple variables such as technological progress, growing researcher acceptance, expanding applications across multiple fields, and market leaders' growth activities. For instance, in May 2021, CELLINK, a bio convergence startup, purchased Visikol Corp.. This U.S.-based contract research services provider provides industry-leading services in digital pathology, multiplex imaging, 3D tissue imaging, and 3D cell culture to pharmaceutical and biotech businesses. 

3D Cell Culture Key Market Players & Competitive Insights

Leading market players are investing heavily in research and development in order to expand their product lines, which will help the 3D cell culture market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, 3D cell culture industry must offer cost-effective items.

Major players in the 3D cell culture market are attempting to increase market demand by investing in research and development operations, including Thermo Fisher Scientific, Inc. (US), Lonza (Switzerland), Corning Incorporated (US), Avantor Inc. (US), Merck KGaA (Germany), and others.

Key Companies in the 3D cell culture market include

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  Thermo Fisher Scientific, Inc. (US)

  
  


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  Lonza (Switzerland)

  
  


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  Corning Incorporated (US)

  
  


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  Avantor Inc. (US)

  
  


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  Merck KGaA (Germany)

  
  

3D Cell Culture Industry Developments

June 2023: The private research university Stanford University in California, the United States, and Sartorius, a global supplier of pharmaceuticals and laboratory equipment, expanded their partnership to create a scalable platform for the large-scale manufacturing of humaniPSCs.

October 2022: With the Elplasia 12K flask, Corning established a novel microcavity geometry that streamlines the processes of spheroid formation, culture, treatment, evaluation, and harvesting. A 125-fold higher yield than conventional 96-well spheroid plates is achieved by the flask, which generates about 12,000 spheroids of uniform size and shape per flask.

3D Cell Culture Market Segmentation

3D Cell Culture Product Outlook

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  Scaffold-based 3D Cell Cultures

  
  


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  Scaffold-free 3D Cell Cultures

  
  


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  Microfluidics-based 3D Cell Cultures

  
  


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  Magnetic & Bioprinted 3D Cell Cultures

  
  

3D Cell Culture Application Outlook

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  Cancer & Stem Cell Research

  
  


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  Drug Discovery & Toxicology Testing

  
  


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  Tissue Engineering & Regenerative Medicine

  
  

3D Cell Culture End User Outlook

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  Pharmaceutical & Biotechnology Companies

  
  


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  Research Institutes

  
  


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  Cosmetics Industry

  
  


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  Other End Users