United States Photodynamic Therapy Market Research Report Information By Product Type (Photosensitizer Drugs and Photodynamic Therapy Devices), By Light Source (Lasers, Light Emitting Diodes (LEDs), Lamps, and Others), By Application (Cancer, Actinic Keratosis (AK), Psoriasis, Acne, and Others), By End User (Hospitals, Cancer Treatment Centers, Cosmetic and Dermatology Clinics, and Others), – United States Market Forecast Till 2032

United States Photodynamic Therapy Market Overview

United States photodynamic therapy market size was valued at USD 1521.2 Billion in 2022. The Photodynamic Therapy market industry is projected to grow from USD 1636.8 Billion in 2023 to USD 2941.01 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 7.60% during the forecast period (2024 - 2032).Rising incidences of skin disorders and cancer and growing government investment in research and development are the main market drivers anticipated to propel the photodynamic therapy market in the United States. 

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

United States Photodynamic Therapy Market Trends

• Increasing demand for the photosensitizer drugs is driving the market growth.

Chemical components or medications known as photosensitizers are used with light to treat various cancer types. The cancer cells are destroyed by photosensitizers, which absorb light and transform into a different form. The regulatory bodies of the world have approved a large number of medications to treat cancer. In September 2021, for example, Soligenix, Inc. reported that the FDA's Office of Orphan Products Development had designated the active ingredient hypericin for use as an orphan drug for the treatment of T-cell lymphoma, expanding the target population beyond cutaneous T-cell lymphoma.

Increasing R&D spending by industry participants to find novel photosensitizers that enhance clinical outcomes is projected to propel the growth of the market CAGR during the projected period. Because of technological developments that have minimized side effects and increased public awareness, photodynamic treatment devices are expected to grow profitably. Increased segmental expansion in the market is anticipated due to the rise in cancer cases and the expanding use of photodynamic therapy as a treatment. According to the National Board of Health and Welfare, the United States Cancer Registry received reports of 68,318 malignant tumors from 62,555 individuals in 2020. The number of cancer-related deaths was significantly lower than the number of people who were diagnosed with the disease. Over the forecast period, the segment is expected to rise due to the increasing application of photodynamic treatment for various cancers, including lung and breast cancer. Additionally, because minimally invasive procedures involve less discomfort, require shorter recovery periods, and have fewer consequences, patients frequently favor them over standard surgical methods. PDT, a minimally invasive technique, supports this preference. Compared to conventional surgical procedures, minimally invasive therapies typically have a smaller financial impact on healthcare. Patients and healthcare professionals find this financial benefit attractive, encouraging PDT's growing use. Patients who receive less invasive treatments can typically return to their regular activities sooner because of their faster recovery. PDT enhances patients' quality of life by its tailored approach, which minimizes damage to healthy tissues. Thus driving the Photodynamic Therapy market revenue.

United States Photodynamic Therapy Market Segment Insights

Photodynamic Therapy Product Type Insights

Based on Product Type, the United States Photodynamic Therapy market segmentation includes photosensitizer drugs and photodynamic therapy devices. The photosensitizer drugs segment mostly dominated the market. Photosensitizer medications ensure a more accurate and targeted course of treatment because they are designed to concentrate in target cells selectively. This selectivity decreases the possibility of damage to the nearby healthy tissues. The positive patient outcomes and expanding acceptance of photodynamic therapy in clinical practice have led to a rise in the use of photosensitizer drugs. Given the widespread use of photodynamic therapy in treating many cancers, photosensitizer drugs are a crucial component of cancer therapy. Accurately targeting and eliminating cancer cells has been a major factor in the popularity of photosensitizer-based photodynamic treatment.

The photodynamic therapy devices category is anticipated to be the fastest growing. Photodynamic therapy is used to treat several dermatological issues, including actinic keratosis, acne, and specific kinds of skin lesions. It works very well to improve the skin's texture and treat precancerous skin disorders. Photodynamic therapy is used in ophthalmology for age-related macular degeneration (AMD) and other eye disorders. Photosensitizing chemicals are injected to target and eliminate aberrant blood vessels in the afflicted eye, and light is delivered to target and eliminate aberrant blood vessels in the afflicted eye.

Figure 1: United States Photodynamic Therapy Market, by Product Type, 2023 & 2032 (USD Billion)

Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

Photodynamic Therapy Light Source Insights

Based on Light Source, the United States Photodynamic Therapy market segmentation includes lasers, light-emitting diodes (LEDs), lamps, and others. The lasers category earned the greatest revenue. The accurate and regulated application of light energy using lasers is necessary to initiate photosensitizing photodynamic treatment (PDT) medications. This precision lessens damage to neighboring healthy tissues while successfully treating the targeted location. Because of their adaptability, lasers can be used for various PDT operations and are employed in a wide range of medical applications. Because laser-based photodynamic therapy (PDT) is concentrated, it has fewer side effects and issues than various other treatment techniques. For several medical conditions, laser-based PDT is the superior choice.

The market for photodynamic therapy light emitting diodes (LEDs) segment is anticipated to grow fastest during the forecast period. In general, LED technology is less expensive than conventional laser systems. Demand for LED-based PDT devices rises because of their cost, which enables a wider range of healthcare facilities to use them.

Photodynamic Therapy Application Insights

Based on Application, the United States Photodynamic Therapy market segmentation includes cancer, actinic keratosis (AK), psoriasis, acne, and others. The cancer category has the largest market share. It is anticipated to increase dramatically shortly. Cancer is a significant and pervasive health risk worldwide. The need for targeted and effective therapeutic techniques, such as photodynamic therapy, has increased due to the rising incidence of many types of cancer.

Additionally, photodynamic therapy has shown promising results in treating several malignancies. It kills cancer cells by using compounds that are photosensitized to light. As patients and medical professionals become more informed about novel and alternative cancer treatments, the need for photodynamic therapy has increased. This is particularly relevant for certain cancer types where PDT has demonstrated potential.

The acne category is expected to have the quickest rate. The customized technique known as photodynamic treatment targets and eliminates acne-causing bacteria and sebaceous glands by using light to activate photosensitizing compounds. In addition, patients are increasingly turning to alternatives to traditional acne treatments, including topical creams and oral medications, which may have unfavorable side effects or be ineffective. Because PDT is non-invasive, has little risk of side effects, and can be tailored to each patient's skin type, it is a popular choice for those seeking effective acne therapy.

Photodynamic Therapy End User Insights

Based on End Users, the United States Photodynamic Therapy market segmentation includes hospitals, cancer treatment centers, cosmetic and dermatology clinics, and others. The hospitals category has the largest market share. Hospitals provide a controlled and established clinical setting necessary for photodynamic therapy administration. PDT treatments are guaranteed safe and effective because hospital infrastructure and facilities are designed to handle medical procedures. For photodynamic therapy, specialized equipment, including light sources and diagnostic instruments, is required. The availability of PDT equipment is constant because hospitals usually have access to state-of-the-art medical technology.

The cosmetic and dermatology clinics category is expected to have the quickest rate. There is an increasing need for cosmetic procedures to address skin conditions and enhance attractiveness. Dermatology and cosmetic clinics offer PDT as an effective, non-invasive treatment option for various skin problems, attracting a larger patient base seeking cosmetic solutions. The benefits of PDT for skin rejuvenation and therapy are now better understood, which has led to increased patient education. Dermatology and cosmetic surgery clinics are essential for the diffusion of knowledge, which helps to explain why PDT treatments are growing in popularity and driving the segment's rise in the photodynamic therapy market.

Photodynamic Therapy Country Insights

The presence of major companies in the United States market, the rise in demand for new biologics to treat cancer, the rapid adoption of photodynamic therapy, and the introduction of new products by industry participants. The actinic keratosis market in the United States is experiencing growth due to several factors, including an increase in the number of cosmetologists offering photodynamic therapy, a rise in product approvals by the US Food and Drug Administration, and a surge in the use of photodynamic therapy for this purpose. In December 2021, Biofrontera Inc. announced that the first participant in a Phase 1 study assessing the safety and tolerability of photodynamic therapy (PDT) for actinic keratosis (AK) had been enrolled. PDT involves utilizing three tubes of Ameluz in conjunction with the company's BF-RhodoLED XL lamp. It is anticipated that these product approvals will propel the US market.

United States Photodynamic Therapy Key Market Players & Competitive Insights

Major industry players are expected to invest extensively in R&D to extend their product lines, which would drive additional growth in the market for photodynamic therapy systems. Players in the industry launch a variety of tactical measures to increase their market penetration in parallel with these significant developments in the market. These actions consist of contracts, mergers and acquisitions, increased investments, cooperation with other businesses, and new product types of light sources. To grow and thrive in a more competitive and dynamic market, it must provide reasonably priced products. This is because of the photodynamic therapy industry.

Major United States Photodynamic Therapy market players are attempting to increase market demand by investing in research and development operations, including Gladerma S.A., Biofrontera, Novartis AG, Lumibird (Quantel Medical), Theralase Technologies Inc., Quest Pharmatech, Inc., Hologic, Inc., Biolitec AG, Photocure ASA, IPG Photonics Corporation, Sun Pharmaceutical Industries Ltd., and Valeant Pharmaceuticals International, Inc.

Key Companies in the United States Photodynamic Therapy market include

• Gladerma S.A.


• Biofrontera


• Novartis AG


• Lumibird (Quantel Medical)


• Theralase Technologies Inc.


• Quest Pharmatech, Inc.


• Hologic, Inc.


• Biolitec AG


• Photocure ASA


• IPG Photonics Corporation


• Sun Pharmaceutical Industries Ltd.


• Valeant Pharmaceuticals International, Inc.

January 2023:The international biopharmaceutical company Biofrontera AG announced that the U.S. Patent Office (USPTO) had sent a notice of allowance for the application "Photodynamic therapy comprising two light exposures at different wavelengths" (US Appl. No. 17/269,816) to its wholly owned subsidiary Biofrontera Bioscience GmbH. This patent covers several inventions related to a novel lighting technique for Photodynamic Therapy (PDT) treatment of dermatological skin disorders.

March 2022:The US patent No. 11,235,169 for the BF-RhodoLED XL illumination device was previously issued to Biofrontera Inc. The company has announced that the device is now listed in the FDA publication "Approved Drug Products with Therapeutic Equivalency Evaluations, or the Orange Book.

United States Photodynamic Therapy Market Segmentation

Photodynamic Therapy Product Type Outlook

• Photosensitizer Drugs


• Photodynamic Therapy Devices

• Lasers


• Light Emitting Diodes (LEDs)


• Lamps


• Others

Photodynamic Therapy Application Outlook

• Cancer


• Actinic Keratosis (AK)


• Psoriasis


• Acne


• Others

Photodynamic Therapy End User Outlook

• Hospitals


• Cancer Treatment Centers


• Cosmetic and Dermatology Clinics


• Others