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    UK Patient Derived Xenograft Model Market

    ID: MRFR/HC/50973-HCR
    200 Pages
    Garvit Vyas
    September 2025

    UK Patient-Derived Xenograft Model Market Research Report By Tumor Type (Lung Cancer, Pancreatic Cancer, Prostate Cancer, Breast Cancer, Other Cancer), By Model Type (Mice, Rats) andBy End-User (Pharmaceutical, Biopharmaceutical Companies, Academic & Research Institutes, CROs, CDMOs)- Forecast to 2035

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    UK Patient Derived Xenograft Model Market Research Report — Global Forecast till 2035 Infographic
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    UK Patient Derived Xenograft Model Market Summary

    The United Kingdom UK Patient-Derived Xenograft Model market is poised for substantial growth, projected to reach 80 million USD by 2035.

    Key Market Trends & Highlights

    UK Patient-Derived Xenograft Model Key Trends and Highlights

    • The market valuation is expected to grow from 14.1 million USD in 2024 to 80 million USD by 2035.
    • A compound annual growth rate (CAGR) of 17.08 percent is anticipated from 2025 to 2035.
    • The increasing demand for personalized medicine is likely to drive market expansion.
    • Growing adoption of patient-derived xenograft models due to their effectiveness in cancer research is a major market driver.

    Market Size & Forecast

    2024 Market Size 14.1 (USD Million)
    2035 Market Size 80 (USD Million)
    CAGR (2025-2035) 17.08%

    Major Players

    Asterand Bioscience, Horizon Discovery, Medimmune, NantCell, Ascendance Biomedical, Crown Bioscience, Tissue Solutions, Thermo Fisher Scientific, OncoOne, Charles River Laboratories, Xenograft Technologies, Genomatix, Irvine Scientific, The Jackson Laboratory, James Harper

    UK Patient Derived Xenograft Model Market Trends

    The UK Patient-Derived Xenograft Model Market is witnessing significant market trends driven by the growing emphasis on personalized medicine and the need for more accurate cancer research models. With the NHS's increasing focus on advanced therapies and precision medicine, there is a heightened demand for innovative research models that can improve drug efficacy and reduce clinical trial failures.

    This shift towards personalized therapies in the UK has made patient-derived xenograft models a vital tool for researchers and pharmaceutical companies, creating a favorable environment for market growth. Opportunities to be explored in this market include collaborations between academic institutions and biotech companies.The UK is home to top research universities and institutes, contributing to groundbreaking advancements in cancer treatment.

    Initiatives such as the UK's Life Science Strategy support these collaborations, allowing researchers to leverage patient-derived xenograft models to explore new therapeutic options more effectively. The increasing investment in R&D, particularly in the field of oncology, further paves the way for innovations in model development. Recent trends indicate a shift towards the integration of advanced technologies, such as gene editing and biomanufacturing, into patient-derived xenograft models.

    The use of these cutting-edge techniques in the UK enhances the relevance and applicability of these models in personalized treatment plans.Additionally, there is a growing interest in the development of organoid cultures and fully humanized models, expanding the capabilities of patient-derived xenografts. As regulatory environments become more supportive of these innovations, the UK market stands to benefit from expanded research applications and improved patient outcomes, solidifying its position as a leader in cancer research and therapeutics.

    Market Segment Insights

    Patient-Derived Xenograft Model Market Tumor Type Insights

    The UK Patient-Derived Xenograft Model Market is witnessing a significant evolution, particularly within the Tumor Type segment, which is gaining pivotal relevance in the realm of oncology research and therapeutic development. As cancer continues to be a leading cause of mortality in the UK, the necessity for precise research models has never been more critical. Tumor Type classifications, including Lung Cancer, Pancreatic Cancer, Prostate Cancer, Breast Cancer, and other variants, play an essential role in tailoring treatments and understanding tumor biology.

    Lung Cancer, noted for its high incidence rates in the UK, dominates the market owing to the pressing need for innovative therapies and research methodologies. This has steered Research and Development efforts toward specialized xenograft models that accurately mimic patient-specific tumors, facilitating personalized medicine approaches. Pancreatic Cancer represents another area of significant research focus due to its aggressive nature and often late-stage diagnosis.

    The demand for Patient-Derived Xenograft Models in this field is increasing as scientists strive to uncover novel treatment pathways. Prostate Cancer, prevalent among men in the UK, fuels a growing need for experimental models that can replicate the complexity of oncogenic processes and therapeutic resistance, which supports advancements in precision oncology. On the other hand, Breast Cancer, noted for its diverse subtype variability, continues to evolve as a focal point for researchers, leveraging xenograft models to explore targeted therapies and understand metastatic behavior.

    Other Cancer types also contribute to the UK Patient-Derived Xenograft Model Market with specific focus areas emerging, as researchers aim to replicate and study various less common malignancies effectively. Understanding the dynamics within the Tumor Type segment is crucial for grasping the overall landscape of the UK Patient-Derived Xenograft Model Market. The advancements in genomic technologies and the push towards personalized approaches further enhance the relevance of these segments, driving market growth as researchers and healthcare providers collaborate to combat the challenges posed by an array of cancers.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Patient-Derived Xenograft Model Market Model Type Insights

    The UK Patient-Derived Xenograft Model Market is experiencing notable growth, particularly in its Model Type segmentation which includes Mice and Rats. The demand for Mice in xenograft models is prominent due to their biological and genetic similarities to humans, making them invaluable for research in understanding tumor biology and drug efficacy. Rats also serve an essential role, offering advantages in pharmacokinetics and toxicology studies, contributing significantly to Research and Development efforts in the biopharmaceutical sector.

    Continued advancements in genetic engineering and the development of more sophisticated models enhance the capabilities of these organisms, aligning with the UK's focus on innovative medical research.Furthermore, the increasing prevalence of cancers and the need for personalized medicine are driving growth in the Patient-Derived Xenograft Model Market. While both Mice and models are critical for preclinical validation, the ongoing enhancement of research methodologies is creating opportunities for expanded applications and improved therapeutic strategies in the UK healthcare industry.

    Patient-Derived Xenograft Model Market End-User Insights

    The UK Patient-Derived Xenograft Model Market is experiencing notable developments across its End-User segment, which encompasses a diverse range of entities including Pharmaceutical companies, Biopharmaceutical companies, Academic and Research Institutes, Contract Research Organizations (CROs), and Contract Development and Manufacturing Organizations (CDMOs). Pharmaceutical and Biopharmaceutical companies leverage patient-derived xenograft models extensively for drug discovery and preclinical testing, enabling the accelerating of drug development processes.

    Academic and Research Institutes are pivotal in pushing the boundaries of cancer research, as they utilize these models to understand disease mechanisms and evaluate treatment efficacy. Additionally, CROs play a significant role by providing essential outsourced research services that enhance efficiency in clinical trials, while CDMOs help streamline the development and manufacturing processes tailored to specific therapeutic needs. The increasing focus on personalized medicine and the rising investment in innovative cancer therapies are expected to drive substantial growth in these segments.

    This upward trend emphasizes the significance of patient-derived xenograft models, bringing opportunities for researchers to explore novel therapeutic avenues tailored to the unique genomic profiles of patients in the UK.

    Get more detailed insights about UK Patient Derived Xenograft Model Market Research Report — Global Forecast till 2035

    Key Players and Competitive Insights

    The UK Patient-Derived Xenograft Model Market has seen significant advancements in recent years, reflecting the growing demand for effective preclinical models that accurately represent human tumors. These models play a crucial role in cancer research and drug development, enabling researchers to test therapeutic responses in conditions that closely mimic the human physiological environment. The competitive landscape is characterized by a mix of established players and emerging companies, all vying for a share of the market while addressing the challenges posed by complex tumor biology and the need for more personalized treatments.

    Robust R&D efforts, strategic collaborations, and the integration of cutting-edge technologies are key drivers for companies seeking to enhance their product offerings and improve market positioning.Asterand Bioscience possesses a strong presence in the UK Patient-Derived Xenograft Model Market, leveraging its extensive expertise in sourcing, characterizing, and developing patient-derived tissues and models. The company is recognized for its commitment to advancing personalized medicine, with a focus on delivering high-quality PDX models that are tailored to specific patient profiles.

    This enables pharmaceutical and biotechnological organizations to gain meaningful insights into therapeutic efficacy and safety. Asterand Bioscience benefits from its substantial biorepository and a wealth of clinical data, which enhance its ability to provide innovative solutions and cater to the unique needs of UK-based researchers and drug developers.Horizon Discovery is another significant player in the UK Patient-Derived Xenograft Model Market, known for its pioneering efforts in gene editing and custom model development.

    The company offers a variety of key products and services, including patient-derived xenografts engineered to express specific genetic alterations, providing vital insights into cancer biology and therapy response. Horizon Discovery’s market presence is strengthened by its focus on innovative scientific solutions and its collaborations with academic institutions and industry partners to push the boundaries of cancer research. The company has continuously invested in expanding its product portfolio and enhancing its capabilities, evidenced by strategic acquisitions that bolster its position within the market.

    With a reputation for excellence in preclinical oncology, Horizon Discovery remains dedicated to supporting the UK's evolving landscape in patient-derived models, catering to the diverse and specialized needs within the healthcare sector.

    Key Companies in the UK Patient Derived Xenograft Model Market market include

    Industry Developments

    Recent developments in the UK Patient-Derived Xenograft Model Market demonstrate significant progress and ongoing activity among key players. Asterand Bioscience continues to innovate in developing quality PDX models that are more representative of patient tumors. Horizon Discovery has recently expanded its services to include advanced genomic editing, enhancing the utility of PDX models in personalized medicine.

    Notably, in August 2022, Crown Bioscience announced its acquisition of the assets of a notable biotech firm, positioning it for rapid growth and expanded offerings in preclinical drug development. Meanwhile, Thermo Fisher Scientific, through strategic partnerships, has integrated advanced technologies to improve PDX model reproducibility. The market shows substantial growth with estimates indicating an increase in valuation due to rising demand for personalized therapies and robust investment in cancer research.

    In the past 2-3 years, there have been substantial advancements in the use of PDX models, notably in synergy with immunotherapy, signaling a pivotal shift in cancer treatment approaches in the UK. The continuous increase in funding for research initiatives underpins these trends, with companies like The Jackson Laboratory leading collaborations aimed at enhancing model applications in translational research.

    Market Segmentation

    Patient-Derived Xenograft Model Market End-User Outlook

    • Pharmaceutical
    • Biopharmaceutical Companies
    • Academic & Research Institutes
    • CROs
    • CDMOs

    Patient-Derived Xenograft Model Market Model Type Outlook

    • Mice
    • Rats

    Patient-Derived Xenograft Model Market Tumor Type Outlook

    • Lung Cancer
    • Pancreatic Cancer
    • Prostate Cancer
    • Breast Cancer
    • Other Cancer

    Report Scope

    Report Scope:
    Report Attribute/Metric Source: Details
    MARKET SIZE 2018 14.12(USD Million)
    MARKET SIZE 2024 16.0(USD Million)
    MARKET SIZE 2035 80.0(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 15.756% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Million
    KEY COMPANIES PROFILED Asterand Bioscience, Horizon Discovery, Medimmune, NantCell, Ascendance Biomedical, Crown Bioscience, Tissue Solutions, Thermo Fisher Scientific, OncoOne, Charles River Laboratories, Xenograft Technologies, Genomatix, Irvine Scientific, The Jackson Laboratory, James Harper
    SEGMENTS COVERED Tumor Type, Model Type, End-User
    KEY MARKET OPPORTUNITIES Growing demand for personalized medicine, Increasing research funding and investment, Advancements in genomic technologies, Expanding applications in oncology, Collaborations between academia and industry
    KEY MARKET DYNAMICS increased cancer research funding, growing demand for personalized medicine, advances in biotechnology, rising prevalence of cancer, need for effective drug testing
    COUNTRIES COVERED UK

    FAQs

    What is the expected market size of the UK Patient-Derived Xenograft Model market in 2024?

    The UK Patient-Derived Xenograft Model market is anticipated to reach a value of 16.0 million USD in 2024.

    What will be the market value of the UK Patient-Derived Xenograft Model market by 2035?

    By 2035, the market is projected to grow to approximately 80.0 million USD.

    What is the expected compound annual growth rate (CAGR) of the UK Patient-Derived Xenograft Model market from 2025 to 2035?

    The market is expected to experience a CAGR of 15.756% during the period from 2025 to 2035.

    Which tumor type is projected to hold the largest market share in the UK Patient-Derived Xenograft Model market by 2035?

    The Breast Cancer segment is expected to dominate the market with a projected value of 20.0 million USD by 2035.

    What are the expected market sizes for Lung Cancer and Pancreatic Cancer in 2024?

    Lung Cancer is projected to be valued at 3.2 million USD and Pancreatic Cancer at 2.4 million USD in 2024.

    What will be the market size for the Prostate Cancer segment by 2035?

    The Prostate Cancer segment is anticipated to reach a market size of 10.0 million USD by 2035.

    Who are the key players in the UK Patient-Derived Xenograft Model market?

    Major players in the market include Asterand Bioscience, Horizon Discovery, Medimmune, and Thermo Fisher Scientific.

    What are the market size projections for the Other Cancer segment in 2024 and by 2035?

    The Other Cancer segment is expected to be valued at 4.4 million USD in 2024 and grow to 22.0 million USD by 2035.

    What is the projected market size for Breast Cancer in 2024?

    The Breast Cancer segment is expected to have a market value of 4.0 million USD in 2024.

    What growth opportunities exist in the UK Patient-Derived Xenograft Model market?

    The growth opportunities stem from advancements in cancer research and the increasing need for personalized medicine solutions.

    Report Infographic
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