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    UK Gene Therapy Market

    ID: MRFR/Pharma/51497-HCR
    200 Pages
    Rahul Gotadki
    September 2025

    UK Gene Therapy Market Research Report By Therapeutic Area (Oncology, Genetic Disorders, Infectious Diseases, Cardiovascular Diseases, Neurological Disorders), By Technology (Viral Vectors, CRISPR, Gene Editing, RNA Therapy, Non-Viral Methods), By Application (Research, Clinical, Commercial) and By Route of Administration (Intravenous, Intramuscular, Intradermal, Intrathecal, Oral)- Forecast to 2035

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    Table of Contents

    UK Gene Therapy Market Summary

    The United Kingdom gene therapy market is projected to experience substantial growth from 322.5 million USD in 2024 to 1820 million USD by 2035.

    Key Market Trends & Highlights

    UK Gene Therapy Key Trends and Highlights

    • The market valuation is expected to rise from 322.5 million USD in 2024 to 1820 million USD by 2035.
    • A compound annual growth rate (CAGR) of 17.04 percent is anticipated for the period from 2025 to 2035.
    • The UK gene therapy market is likely to expand significantly, reflecting increasing investment in innovative treatments.
    • Growing adoption of gene therapy due to advancements in genetic research is a major market driver.

    Market Size & Forecast

    2024 Market Size 322.5 (USD Million)
    2035 Market Size 1820 (USD Million)
    CAGR (2025-2035) 17.04%

    Major Players

    Finite Resources, Amgen, Bluebird Bio, Pfizer, Regeneron Pharmaceuticals, Roche, GSK, Sarepta Therapeutics, Regenxbio, Spark Therapeutics, Celgene, AstraZeneca, Bristol Myers Squibb, Novartis, uniQure

    UK Gene Therapy Market Trends

    The UK Gene Therapy Market is experiencing several significant trends that highlight its dynamic nature. One key market driver is the increasing prevalence of genetic disorders and chronic diseases, which has led to a higher demand for innovative treatment options. The UK government’s commitment to advancing healthcare technology, along with substantial funding for research and development, is propelling the growth of gene therapies. Furthermore, partnerships between UK biotech firms and global pharmaceutical companies are fostering innovation and enhancing the availability of gene therapies. 

    Recently, there has been a notable shift towards personalized medicine within the UK.Tailoring treatments based on individual genetic profiles is becoming more prevalent, as it offers the potential for more effective therapies. This trend is supported by advancements in genetic testing technologies that allow for more precise patient selection, ultimately driving the adoption of gene therapies. The regulatory environment in the UK has also adapted to be more accommodating, with streamlined approval processes for innovative therapies.

    This encourages companies to invest in gene therapy development, reflecting an overall trend towards faster and more efficient product launches. Opportunities for growth in the UK Gene Therapy Market can be explored by focusing on rare diseases, where gene therapies can provide significant benefits.The government's initiatives to support healthcare innovations, including funding for clinical trials, open avenues for companies to bring their therapies to market. Additionally, collaboration between academic institutions and industry players is expected to lead to breakthroughs in gene therapy research, enhancing the UK’s position as a leader in this field. 

    As the UK prioritizes biotechnology and genomic research, the landscape for gene therapies continues to evolve, presenting various chances for players in this market to expand their reach and impact.

    UK Gene Therapy Market Drivers

    Market Segment Insights

    UK Gene Therapy Market Segment Insights

    UK Gene Therapy Market Segment Insights

    Gene Therapy Market Therapeutic Area Insights

    Gene Therapy Market Therapeutic Area Insights

    The UK Gene Therapy Market, particularly within the Therapeutic Area segment, demonstrates a promising trajectory driven by advancements in biotechnology and an increasing need for effective treatment options. This market has observed significant dynamics due to the rising prevalence of chronic diseases and genetic disorders, alongside the growing recognition of gene therapy's potential to address these challenges. Oncology remains a crucial focus area, fueled by a high demand for innovative cancer treatments, with gene therapies offering new hope for patients who have exhausted other options.

    Genetic disorders are also pivotal, as genetic modifications hold the potential to correct rare inherited conditions, thereby improving patient quality of life and reducing long-term healthcare costs. Furthermore, infectious diseases are gaining attention in the context of gene therapy, particularly in vaccine development and therapeutics, especially highlighted during recent global health challenges. The cardiovascular disease segment is increasingly leveraging gene therapy to tackle complex conditions, including heart failure, thereby pushing the boundaries of traditional treatments.

    Neurological disorders represent another vital area of growth, nascent with therapeutic interventions aimed at conditions like Alzheimer’s disease and Parkinson’s disease, which affect a significant portion of the UK's aging population. Each of these categories contributes to the diversification and expansion of the UK Gene Therapy Market, highlighting the country's commitment to harnessing innovative treatments that can transform patient outcomes. The intersection of these therapeutic areas reflects not only the medical needs within the UK but also aligns with the government's push toward investing in innovative healthcare solutions as part of the long-term health strategy.

    The implication of government initiatives aimed at facilitating Research and Development is evident, providing a supportive framework for the commercialization of gene therapies across various disease categories, allowing the UK to position itself as a leader in this burgeoning field. The overall segmentation of the UK Gene Therapy Market, grounded in its Therapeutic Area, underscores not only the growth potential but also the necessity for sustained investment and regulatory support to navigate challenges that include patient access, ethical considerations, and market adoption for these advanced therapies.

    Gene Therapy Market Technology Insights

    Gene Therapy Market Technology Insights

    The Technology segment of the UK Gene Therapy Market encompasses various innovative approaches that drive advancements in treating genetic disorders. Viral Vectors have gained prominence due to their efficiency in delivering therapeutic genes, making them a critical tool in Gene Therapy applications. CRISPR technology has revolutionized the field by providing accurate and efficient gene editing capabilities, propelling research and therapeutic developments.

    Gene Editing continues to be a focal area as it allows for precise alterations in the genome, facilitating the treatment of a wide range of genetic conditions.RNA Therapy emerged as a powerful method for modulating gene expression, showing significant potential in treating diseases at the molecular level. 

    Non-viral methods are also gaining traction, offering safer alternatives to gene delivery without the associated risks of viral vectors. These diverse technology approaches not only highlight the innovative methodologies being deployed within the UK Gene Therapy Market but also underscore the opportunities for enhancing treatment efficacy and patient outcomes in genetic therapies. Overall, the Technology segment is integral for driving the growth and future success of Gene Therapy in the UK, empowering advancements in the field and addressing unmet medical needs.

    Gene Therapy Market Application Insights

    Gene Therapy Market Application Insights

    The UK Gene Therapy Market is characterized by its diverse Application segment, which plays a crucial role in both the therapeutic landscape and advancements in medical science. This segment is predominantly divided into Research, Clinical, and Commercial applications, each serving specific purposes. Research applications are pivotal in driving innovations and facilitating the development of new therapies, showcasing significant activities in universities and biotechnology firms. Clinical applications focus on the translation of these innovations into effective treatments for various genetic disorders, emphasizing the importance of safety and efficacy in patient outcomes.

    Meanwhile, Commercial applications highlight the industry's efforts to bring these therapies to market, addressing the growing demand for personalized medicine. The market dynamics reflect a strong emphasis on patient-centric solutions and are bolstered by favorable governmental policies aimed at encouraging research and development initiatives. With ongoing advancements in technology and a robust healthcare infrastructure in the UK, the Application segment of the UK Gene Therapy Market is well-positioned for substantial growth, offering numerous opportunities for stakeholders across all levels of the industry.

    This focus on applications reinforces the significance of gene therapy as a transformative approach to treatment, paving the way for the future of medicine in the UK.

    Gene Therapy Market Route of Administration Insights

    Gene Therapy Market Route of Administration Insights

    The Route of Administration segment within the UK Gene Therapy Market plays a crucial role in the efficient delivery of therapeutic agents to patients, addressing diverse medical conditions. The market encompasses various methods, including Intravenous, Intramuscular, Intradermal, Intrathecal, and Oral administration. Among these, Intravenous delivery holds significant importance, often chosen for its rapid onset of action and ability to deliver large volumes, making it suitable for complex therapies. Intramuscular administration is another vital route, particularly valued for its ease of use and provisions for self-administration, enhancing patient compliance.

    Intradermal and Intrathecal methods are critical for targeting localized conditions and central nervous system disorders, respectively, which are prevalent in the UK healthcare landscape. Oral administration, while less common in gene therapy, represents an emerging frontier, providing a non-invasive delivery option that could improve accessibility for patients.

    As the UK Gene Therapy Market continues to expand, advancements in administration techniques may overcome existing challenges, driving market growth and offering new therapeutic opportunities.With a robust investment in Research and Development, the UK aims to remain at the forefront of innovative gene therapies, further solidifying the significance of the Route of Administration segment.

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    Regional Insights

    Key Players and Competitive Insights

    The UK Gene Therapy Market is witnessing transformative growth driven by advancements in biotechnology and an increasing focus on personalized medicine. This sector is characterized by intense competition among a range of players, from established pharmaceutical giants to emerging biotech firms. The landscape is notably shaped by regulatory frameworks, funding opportunities, and the demand for innovative treatments targeting rare and complex genetic disorders. As the market evolves, companies are continuously striving to enhance their product pipelines, engage in strategic collaborations, and leverage cutting-edge technologies to maintain a competitive edge. 

    The competitive insights highlight the strategic positioning of organizations, revealing key trends and areas of investment that could define the future of gene therapy in the UK.Finite Resources has been making strides within the UK Gene Therapy Market, capitalizing on its streamlined operations and innovative approach to genetic treatments. The company leverages its expertise in gene delivery systems and has established strong alliances with research institutions and healthcare providers, bolstering its market presence. This strategic positioning allows Finite Resources to quickly adapt to emerging trends and meet the growing demand for gene therapies in the UK. 

    Additionally, their focus on developing targeted therapies brings forth a unique strength that appeals to patients and healthcare systems seeking efficient solutions. The adaptability and agility of Finite Resources in navigating regulatory landscapes and market dynamics further solidify its competitive standing in the rapidly evolving gene therapy space.Amgen, a significant player in the UK Gene Therapy Market, has a robust portfolio of innovative products and services aimed at addressing unmet medical needs. The company is actively involved in the development and commercialization of gene therapies that target various genetic conditions, leveraging its advanced research capabilities and extensive clinical experience. 

    Key products have begun to emerge as transformative treatments, and Amgen’s ongoing commitment to research and development fosters a culture of innovation. The company's market presence is augmented by strategic mergers and acquisitions that enhance its technological capabilities and expand its therapeutic offerings in the UK. Amgen’s strong financial position allows for substantial investments in clinical trials and collaborations, further strengthening its competitive advantage in the gene therapy domain, ensuring they remain at the forefront of this revolutionary market.

    Key Companies in the UK Gene Therapy Market market include

    Industry Developments

    The UK Gene Therapy Market is experiencing significant advancements, underscored by recent developments in various companies. Finite Resources, Amgen, and GSK are exploring innovative gene therapies to treat genetic disorders, while Bluebird Bio is progressing with trials for its gene editing technologies. In August 2023, Pfizer announced a strategic collaboration with uniQure, aimed at developing gene therapies targeting rare diseases, enhancing their position in the UK market. Furthermore, AstraZeneca remains committed to its gene therapy initiatives, with plans to expand Research and Development efforts in the UK. 

    The gene therapy sector is projected to see substantial valuation growth, influenced by advancements in technology and increased government support for biotechnology initiatives, reflecting the UK's strategic prioritization of healthcare innovation. Notably, in 2022, Roche completed its acquisition of Spark Therapeutics, further consolidating the gene therapy landscape in the UK. The last two to three years have seen a surge in investment and research activities, with financial backing from both private and public sectors bolstering major players like Bristol Myers Squibb, Novartis, and Celgene in their gene therapy endeavors.

    Market Segmentation

    Outlook

    • Intravenous
    • Intramuscular
    • Intradermal
    • Intrathecal
    • Oral

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2023 322.5(USD Million)
    MARKET SIZE 2024 363.5(USD Million)
    MARKET SIZE 2035 1820.0(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 15.77% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Million
    KEY COMPANIES PROFILED Finite Resources, Amgen, Bluebird Bio, Pfizer, Regeneron Pharmaceuticals, Roche, GSK, Sarepta Therapeutics, Regenxbio, Spark Therapeutics, Celgene, AstraZeneca, Bristol Myers Squibb, Novartis, uniQure
    SEGMENTS COVERED Therapeutic Area, Technology, Application, Route of Administration
    KEY MARKET OPPORTUNITIES Increasing prevalence of genetic disorders, Advancements in CRISPR technology, Growing demand for personalized medicine, Expanding pipeline of clinical trials, Supportive regulatory environment for approvals
    KEY MARKET DYNAMICS regulatory approvals, technological advancements, increasing investments, rising disease prevalence, growing patient awareness
    COUNTRIES COVERED UK

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the expected market size of the UK Gene Therapy Market in 2024?

    The UK Gene Therapy Market is expected to be valued at 363.5 USD Million in 2024.

    What is the projected market size for the UK Gene Therapy Market by 2035?

    By 2035, the UK Gene Therapy Market is anticipated to reach a value of 1820.0 USD Million.

    What is the expected compound annual growth rate (CAGR) for the UK Gene Therapy Market from 2025 to 2035?

    The expected CAGR for the UK Gene Therapy Market is 15.77 % for the period from 2025 to 2035.

    Which therapeutic area holds the largest market share in the UK Gene Therapy Market?

    The oncology segment is projected to have a market value of 100.0 USD Million in 2024, making it the highest within the UK Gene Therapy Market.

    What will be the market value for the genetic disorders segment in the UK Gene Therapy Market by 2035?

    The genetic disorders segment is expected to reach a market value of 450.0 USD Million by 2035.

    Who are the major players in the UK Gene Therapy Market?

    Key players in the UK Gene Therapy Market include Amgen, Pfizer, and Roche among others.

    What is the expected market size for the infectious diseases segment in the UK Gene Therapy Market by 2035?

    The infectious diseases segment is anticipated to grow to a market size of 400.0 USD Million by 2035.

    What is the projected market value for cardiovascular diseases in the UK Gene Therapy Market in 2024?

    The cardiovascular diseases segment is expected to be valued at 50.0 USD Million in 2024.

    What is the expected market size for neurological disorders in the UK Gene Therapy Market in 2035?

    The neurological disorders segment is projected to reach a value of 220.0 USD Million by 2035.

    What growth opportunities exist in the UK Gene Therapy Market?

    Emerging trends such as increased research funding and advancements in technology present significant growth opportunities in the UK Gene Therapy Market.

    1. EXECUTIVE SUMMARY
    2. Market Overview
    3. Key Findings
    4. Market Segmentation
    5. Competitive Landscape
    6. Challenges and Opportunities
    7. Future Outlook
    8. MARKET INTRODUCTION
    9. Definition
    10. Scope of the study
    11. Research Objective
    12. Assumption
    13. Limitations
    14. RESEARCH METHODOLOGY
    15. Overview
    16. Data Mining
    17. Secondary Research
    18. Primary Research
    19. Primary Interviews and Information Gathering Process
    20. Breakdown of Primary Respondents
    21. Forecasting Model
    22. Market Size Estimation
    23. Bottom-Up Approach
    24. Top-Down Approach
    25. Data Triangulation
    26. Validation
    27. MARKET DYNAMICS
    28. Overview
    29. Drivers
    30. Restraints
    31. Opportunities
    32. MARKET FACTOR ANALYSIS
    33. Value chain Analysis
    34. Porter's Five Forces Analysis
    35. Bargaining Power of Suppliers
    36. Bargaining Power of Buyers
    37. Threat of New Entrants
    38. Threat of Substitutes
    39. Intensity of Rivalry
    40. COVID-19 Impact Analysis
    41. Market Impact Analysis
    42. Regional Impact
    43. Opportunity and Threat Analysis
    44. UK Gene Therapy Market, BY Therapeutic Area (USD Million)
    45. Oncology
    46. Genetic Disorders
    47. Infectious Diseases
    48. Cardiovascular Diseases
    49. Neurological Disorders
    50. UK Gene Therapy Market, BY Technology (USD Million)
    51. Viral Vectors
    52. CRISPR
    53. Gene Editing
    54. RNA Therapy
    55. Non-Viral Methods
    56. UK Gene Therapy Market, BY Application (USD Million)
    57. Research
    58. Clinical
    59. Commercial
    60. UK Gene Therapy Market, BY Route of Administration (USD Million)
    61. Intravenous
    62. Intramuscular
    63. Intradermal
    64. Intrathecal
    65. Oral
    66. Competitive Landscape
    67. Overview
    68. Competitive Analysis
    69. Market share Analysis
    70. Major Growth Strategy in the Gene Therapy Market
    71. Competitive Benchmarking
    72. Leading Players in Terms of Number of Developments in the Gene Therapy Market
    73. Key developments and growth strategies
    74. New Product Launch/Service Deployment
    75. Merger & Acquisitions
    76. Joint Ventures
    77. Major Players Financial Matrix
    78. Sales and Operating Income
    79. Major Players R&D Expenditure. 2023
    80. Company Profiles
    81. Finite Resources
    82. Financial Overview
    83. Products Offered
    84. Key Developments
    85. SWOT Analysis
    86. Key Strategies
    87. Amgen
    88. Financial Overview
    89. Products Offered
    90. Key Developments
    91. SWOT Analysis
    92. Key Strategies
    93. Bluebird Bio
    94. Financial Overview
    95. Products Offered
    96. Key Developments
    97. SWOT Analysis
    98. Key Strategies
    99. Pfizer
    100. Financial Overview
    101. Products Offered
    102. Key Developments
    103. SWOT Analysis
    104. Key Strategies
    105. Regeneron Pharmaceuticals
    106. Financial Overview
    107. Products Offered
    108. Key Developments
    109. SWOT Analysis
    110. Key Strategies
    111. Roche
    112. Financial Overview
    113. Products Offered
    114. Key Developments
    115. SWOT Analysis
    116. Key Strategies
    117. GSK
    118. Financial Overview
    119. Products Offered
    120. Key Developments
    121. SWOT Analysis
    122. Key Strategies
    123. Sarepta Therapeutics
    124. Financial Overview
    125. Products Offered
    126. Key Developments
    127. SWOT Analysis
    128. Key Strategies
    129. Regenxbio
    130. Financial Overview
    131. Products Offered
    132. Key Developments
    133. SWOT Analysis
    134. Key Strategies
    135. Spark Therapeutics
    136. Financial Overview
    137. Products Offered
    138. Key Developments
    139. SWOT Analysis
    140. Key Strategies
    141. Celgene
    142. Financial Overview
    143. Products Offered
    144. Key Developments
    145. SWOT Analysis
    146. Key Strategies
    147. AstraZeneca
    148. Financial Overview
    149. Products Offered
    150. Key Developments
    151. SWOT Analysis
    152. Key Strategies
    153. Bristol Myers Squibb
    154. Financial Overview
    155. Products Offered
    156. Key Developments
    157. SWOT Analysis
    158. Key Strategies
    159. Novartis
    160. Financial Overview
    161. Products Offered
    162. Key Developments
    163. SWOT Analysis
    164. Key Strategies
    165. uniQure
    166. Financial Overview
    167. Products Offered
    168. Key Developments
    169. SWOT Analysis
    170. Key Strategies
    171. References
    172. Related Reports
    173. UK Gene Therapy Market SIZE ESTIMATES & FORECAST, BY THERAPEUTIC AREA, 2019-2035 (USD Billions)
    174. UK Gene Therapy Market SIZE ESTIMATES & FORECAST, BY TECHNOLOGY, 2019-2035 (USD Billions)
    175. UK Gene Therapy Market SIZE ESTIMATES & FORECAST, BY APPLICATION, 2019-2035 (USD Billions)
    176. UK Gene Therapy Market SIZE ESTIMATES & FORECAST, BY ROUTE OF ADMINISTRATION, 2019-2035 (USD Billions)
    177. PRODUCT LAUNCH/PRODUCT DEVELOPMENT/APPROVAL
    178. ACQUISITION/PARTNERSHIP
    179. MARKET SYNOPSIS
    180. UK GENE THERAPY MARKET ANALYSIS BY THERAPEUTIC AREA
    181. UK GENE THERAPY MARKET ANALYSIS BY TECHNOLOGY
    182. UK GENE THERAPY MARKET ANALYSIS BY APPLICATION
    183. UK GENE THERAPY MARKET ANALYSIS BY ROUTE OF ADMINISTRATION
    184. KEY BUYING CRITERIA OF GENE THERAPY MARKET
    185. RESEARCH PROCESS OF MRFR
    186. DRO ANALYSIS OF GENE THERAPY MARKET
    187. DRIVERS IMPACT ANALYSIS: GENE THERAPY MARKET
    188. RESTRAINTS IMPACT ANALYSIS: GENE THERAPY MARKET
    189. SUPPLY / VALUE CHAIN: GENE THERAPY MARKET
    190. GENE THERAPY MARKET, BY THERAPEUTIC AREA, 2025 (% SHARE)
    191. GENE THERAPY MARKET, BY THERAPEUTIC AREA, 2019 TO 2035 (USD Billions)
    192. GENE THERAPY MARKET, BY TECHNOLOGY, 2025 (% SHARE)
    193. GENE THERAPY MARKET, BY TECHNOLOGY, 2019 TO 2035 (USD Billions)
    194. GENE THERAPY MARKET, BY APPLICATION, 2025 (% SHARE)
    195. GENE THERAPY MARKET, BY APPLICATION, 2019 TO 2035 (USD Billions)
    196. GENE THERAPY MARKET, BY ROUTE OF ADMINISTRATION, 2025 (% SHARE)
    197. GENE THERAPY MARKET, BY ROUTE OF ADMINISTRATION, 2019 TO 2035 (USD Billions)
    198. BENCHMARKING OF MAJOR COMPETITORS

    UK Gene Therapy Market Segmentation

     

    • Gene Therapy Market By Therapeutic Area (USD Million, 2019-2035)

      • Oncology
      • Genetic Disorders
      • Infectious Diseases
      • Cardiovascular Diseases
      • Neurological Disorders

     

    • Gene Therapy Market By Technology (USD Million, 2019-2035)

      • Viral Vectors
      • CRISPR
      • Gene Editing
      • RNA Therapy
      • Non-Viral Methods

     

    • Gene Therapy Market By Application (USD Million, 2019-2035)

      • Research
      • Clinical
      • Commercial

     

    • Gene Therapy Market By Route of Administration (USD Million, 2019-2035)

      • Intravenous
      • Intramuscular
      • Intradermal
      • Intrathecal
      • Oral

     

     

     

     

     

     

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