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L-Citrulline Market Analysis

ID: MRFR//0315-CR | 97 Pages | Author: Anshula Mandaokar| November 2018

The global personal care industry, valued at approximately USD 450 billion in 2017, is poised for nearly 4% growth in the coming years. While mature markets like North America and Europe are expected to experience moderate growth, developing markets in Asia-Pacific and the Middle East & Africa present substantial growth potential. Notably, China, contributing nearly 10% of the global personal care industry revenue, is projected to achieve a Compound Annual Growth Rate (CAGR) of around 8% during the forecast period. This growth is attributed to factors such as rapid urbanization, increased disposable income, and evolving consumer lifestyles in the region.
L-citrulline plays a significant role in the cosmetics industry, being utilized in facial moisturizers, sunscreens, and anti-aging treatments due to its antioxidant properties. The presence of citrulline malate in the cosmetics and personal care sector is expected to create lucrative opportunities for market players. The exfoliating properties of malic acid, a component of citrulline malate, make it particularly suitable for use in skincare products, adding to its attractiveness in the industry.

In regions like Asia and the Middle East, there is a notable preference for skin lightening products. This demand is driven by societal standards that place importance on fair complexions, particularly among the youth and female population. Instances of social discrimination based on skin color contribute to the popularity of skin lightening products. In China, skincare products represent approximately 37% of the overall cosmetics and personal care market, with skin lightening products experiencing double-digit growth.

Skincare products rank as the second most popular category in the personal care market in the Middle East, following fragrances. The increasing demand for skin whitening products and cosmetics in both Asian and Middle Eastern markets presents an attractive prospect for citrulline malate manufacturers. As these regions continue to exhibit a growing appetite for personal care items, citrulline malate is likely to find significant opportunities for expansion in the coming years.

Covered Aspects:

Report Attribute/Metric Details
Segment Outlook Type, Classification, Application, and Region

Global L-Citrulline Market Overview


L-Citrulline Market Size was valued at USD 0.12 Billion in 2023. The L-Citrulline industry is projected to grow from USD 0.13 Billion in 2024 to USD 0.19 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 5.12% during the forecast period (2024 - 2032). Rising consumer knowledge of L-citrulline's health advantages is the key market driver enhancing market growth.


L-Citrulline Market Overview


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


L-Citrulline Market Trends




  • High adoption of L-Citrulline in different beneficial ways is driving market growth.




Market CAGR for L-Citrulline is driven by the significant impact of consumers' lifestyles that are changing quickly in tandem with rising disposable income levels. Following this, the rising incidence of diseases like dementia, Alzheimer's, sickle cell anemia, and erectile dysfunction, among others, has drawn the attention of drug manufacturers to the healthcare industry, which is also acting as a key factor favoring the growth of the l-citrulline market over the forecast period. The l-citrulline market is expanding favorably due to the extensive interest in this organic molecule obtained from plants and animals. L-citrulline offers many health benefits that have attracted a lot of media attention.


Additionally, the product's widespread use as a nutritional supplement is the main driver of the market's expansion. Besides this, the market for l-citrulline is expanding due to the rising demand for food items, nutrient-rich beverages, and energy drinks. However, the low growth rate of the feed industry may serve as a major barrier to the l-citrulline market's growth rate during the forecast period. In contrast, the sharp decline in livestock production may threaten the market's expansion during the abovementioned forecast.


Furthermore, the rising product adoption across various industries and the rising use of the ingredient in producing active pharmaceutical ingredients (APIs) in the healthcare industry will present many additional opportunities for growth for the l-citrulline market during the abovementioned forecast because of the many advantages that come with L-Citrulline, such as its use in energy drinks, foods, and beverages, and its ability to detect chronic diseases early.


For instance, China's Ningbo Sinorigin Bio-Products Co., Ltd. is heavily investing in research and development to expand its client base and get a competitive advantage in the future market. Thus, driving the l-citrulline market revenue.

February 2024


ZOA+ Powder, an evolution of the brand's pre-workout drink, contains L-Citrulline and SETRIA L-Glutathione for nitric oxide support, beta alanine, betaine anhydrous, and CON-CRÉT Creatine HCl for endurance, L-Tyrosine, Alpha GPC, and ginkgo biloba for focus, green coffee and Ilex Guayusa for energy, and electrolytes for hydration. A 25-serving tub of fruit punch, wild berry, or cherry lime.


Dave Rienzi, ZOA's chief innovation officer and fitness professional, told NutraIngredients-USA before the 2023 launch that ZOA's focus on leading ingredients and quality will give athletes a premium product that maximizes performance and empowers and inspires them.


L-Citrulline Market Segment Insights


L-Citrulline Type Insights


The l-citrulline market segmentation, based on type, includes powder type and crystal type. The powder-type segment dominated the market, accounting for 56% of market revenue (0.06 Billion). It is more profitable to manufacture beverages in powder form than in liquid form since powder has several advantages over liquid in terms of transportation and storage costs.


L-Citrulline Classification Insights


The l-citrulline market segmentation, based on classifications, includes medical grade and food grade. The food grade category generated the most income (70.4%), with the highest CAGR. L-citrulline is a naturally occurring amino acid complex created by the human body naturally and is also present in some food items. It is good for the health.


L-Citrulline Application Insights


The l-citrulline market segmentation, based on application, includes cosmetic & personal care, food & beverages, agriculture, pharmaceuticals, animal feed, and others. The food and beverages category generated the most income (60.3%), with the highest CAGR. The main causes of this increase are increased disposable income, rapid urbanisation, altered lifestyles, and rising demand for sports nutrition and nutritional supplements, among other factors. Throughout the forecast period, rising protein-rich food and beverage consumption is anticipated to benefit the market as a whole.


Figure 1: L-Citrulline Market by Application, 2022 & 2032 (USD Billion)


L-Citrulline Market by Application, 2022 & 2032


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


L-Citrulline Regional Insights


By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American l-citrulline market will dominate this market, as it is assumed that the North American area is displaying a good growth rate towards the L-Citrulline market during the anticipated period because of strong nations like Canada and the U.S.


Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2: L-CITRULLINE MARKET SHARE BY REGION 2022 (USD Billion)


L-CITRULLINE MARKET SHARE BY REGION 2022


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


Europe's l-citrulline market accounts for the second-largest market share because Germany is the leading nation in Europe, and numerous well-known food and beverage producers exist. The demand for L-citrulline may increase in the next years due to investments in the cosmetics industry and the growing personal care market. Further, the German l-citrulline market held the largest market share, and the UK l-citrulline market was the second-largest growing market in the European region.


The Asia-Pacific l-citrulline market is expected to grow at the fastest CAGR from 2023 to 2032. This is due to the existence of several developing nations, including China, India, Japan, South Korea, and others, whose per capita income levels have dramatically increased. Additionally, there is a movement toward changing consumer food patterns. Moreover, China’s l-citrulline market held the largest market share, and the Indian l-citrulline market was the fastest-growing market in the Asia-Pacific region.


L-Citrulline Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development to expand their product lines, which will help the l-citrulline market, grow even more. Participants in the market are also engaging in a variety of strategic initiatives to footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, the l-citrulline industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics manufacturers use in the l-citrulline industry to benefit clients and increase the market sector. In recent years, the l-citrulline industry has offered some of the most significant advantages. Major players in the l-citrulline market, including Premium Ingredient Co., Ltd (China), MH2 Biochemical Co., Ltd (South Korea), Nutra Green Biotechnology Co., Ltd (U.K.), Santo Jiahe Biotech (China), Wuhan Soleado Technology Co., Ltd. (China), Newseed Chemical Co., Limited (China), TCI Chemicals Private Limited (India), Ningbo Sinorigin Bio-Products Co., Ltd. (China), Merck KGaA (Germany), Kyowa Hakko Bio Co. Ltd. (Japan).


Kyowa Hakko Bio Co. Ltd. provides specialty chemical products. Amino and nucleic acids are the main products the company produces and sells for use in industry and pharmaceuticals. Additionally, bulk medications are made by Kyowa Hakko Bio. For instance, in April 2017, An amino acid mixture called "Setria Performance Blend" by KYOWA HAKKO BIO CO.LTD. was introduced; it contains l-citrulline and is intended to increase the body's synthesis of nitric oxide (NO). The sports nutrition market is anticipated to be a big buyer of this product.


Ningbo Sypo Industry Co. Ltd. manufactures home furniture-related products. The company manufactures pedals, brakes, derailleurs, child car seats, and other bicycle components. Products from Ningbo Sypo Industry are sold both domestically and abroad. For instance, China's Ningbo Sinorigin Bio-Products Co., Ltd. is heavily investing in research and development to expand its client base and get a competitive advantage in the future market.


Key Companies in the L-Citrulline market include



  • Premium Ingredient Co., Ltd (China)

  • MH2 Biochemical Co., Ltd (South Korea)

  • Nutra Green Biotechnology Co., Ltd (U.K.)

  • Santo Jiahe Biotech (China)

  • Wuhan Soleado Technology Co., Ltd. (China)

  • Newsfeed Chemical Co., Limited (China)

  • TCI Chemicals Private Limited (India)

  • Ningbo Sinorigin Bio-Products Co., Ltd. (China)

  • Merck KGaA (Germany)

  • Kyowa Hakko Bio Co. Ltd. (Japan)


L-Citrulline Industry Developments


July 2021: The three newest pre-workout supplements from Steel Supplements have been released, providing the endurance, energy, and power needed to get through the toughest exercises. The most recent exercises, Pumped AF, PRE, and N.O.7, are designed to help users, from novices to fitness enthusiasts, get the most out of their workouts. L-Theanine, L-Phenylalanine, Lion's Mane extract, Kre-Alkalyn, Beta-Alanine, Vitamins B12, B9, B3, B6, Caffeine Anhydrous, beetroot extract, L-Tyrosine, and L-Citrulline are a few of the important substances employed in these newest products.


May 2021: - Anther is the only patented, plant-based daily supplement created specifically for young and long-term penile wellness, and it is currently on sale at antherwellness.com. At age 30, most men begin to experience problems with those muscles, and from that point on, nature might continually test a man's strength to a greater extent. L-Citrulline, Ginger, Muira Puama, and Paullinia Cupana are just a few plant-based constituents in Anther.


April 2018: In the production facility located at Jombang, Indonesia, CJ CheilJedang Corp. declared its intentions to start a production line exclusively dedicated to producing l-arginine and l-citrulline.


L-Citrulline Market Segmentation


L-Citrulline Type Outlook



  • Powder Type

  • Crystal Type


L-Citrulline Classification Outlook



  • Medical Grade

  • Food Grade


L-Citrulline Applications Outlook



  • Cosmetic & Personal Care

  • Food & Beverages

  • Agriculture

  • Pharmaceuticals

  • Animal Feed

  • Other


L-Citrulline Regional Outlook



  • North America

    • US

    • Canada



  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe



  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific



  • Rest of the World

    • Middle East

    • Africa

    • Latin America



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