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    Japan Gene Therapy Market

    ID: MRFR/Pharma/51500-HCR
    200 Pages
    Rahul Gotadki
    September 2025

    Japan Gene Therapy Market Size, Growth Research Report By Therapeutic Area (Oncology, Genetic Disorders, Infectious Diseases, Cardiovascular Diseases, Neurological Disorders), By Technology (Viral Vectors, CRISPR, Gene Editing, RNA Therapy, Non-Viral Methods), By Application (Research, Clinical, Commercial) and By Route of Administration (Intravenous, Intramuscular, Intradermal, Intrathecal, Oral)- Competitor Industry Analysis and Trends Forecast Till 2035

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    Table of Contents

    Japan Gene Therapy Market Summary

    The Japan Gene Therapy market is poised for substantial growth, projected to reach 872.4 USD Million by 2035 from 193.5 USD Million in 2024.

    Key Market Trends & Highlights

    Japan Gene Therapy Key Trends and Highlights

    • The market is expected to grow from 193.5 USD Million in 2024 to 872.4 USD Million by 2035.
    • A compound annual growth rate (CAGR) of 14.67% is anticipated from 2025 to 2035.
    • The increasing prevalence of genetic disorders in Japan is likely to drive market expansion.
    • Growing adoption of innovative gene therapies due to advancements in biotechnology is a major market driver.

    Market Size & Forecast

    2024 Market Size 193.5 (USD Million)
    2035 Market Size 872.4 (USD Million)
    CAGR (2025-2035) 14.67%

    Major Players

    BristolMyers Squibb, Genetzis, Pfizer, Sangamo Therapeutics, CRISPR Therapeutics, UniQure, Roche, bluebird bio, Voyager Therapeutics, Astellas Pharma, Genoa, AbbVie, Novartis, Mitsubishi Tanabe Pharma, Takeda Pharmaceutical

    Japan Gene Therapy Market Trends

    The Japan gene therapy market is witnessing a significant surge, driven by factors such as increasing prevalence of genetic disorders and a rising demand for innovative treatment options. The Japanese government has shown strong support for gene therapy research and development, exemplified by initiatives to streamline the approval processes for new therapies. This is further motivated by a distinct aging population that faces a higher incidence of chronic diseases, fueling the need for advanced therapeutic solutions. 

    Recent trends in Japan indicate a growth in partnerships between biotech companies and research institutions, fostering collaboration that enhances the development of gene therapies.There is a growing interest in personalized medicine, with researchers focusing on tailored treatments that cater to individual genetic profiles. This aligns with Japan's commitment to innovation in healthcare, as seen in its Drug Innovation Strategy, which encourages the development of cutting-edge medical treatments. 

    Opportunities abound in the Japan gene therapy market, particularly in addressing rare genetic diseases that currently have limited treatment options. The rising investment in regenerative medicine is also creating avenues to enhance gene therapy technologies, making them more widely applicable. Furthermore, advancements in CRISPR and other gene editing technologies are paving the way for new treatment possibilities.As the market evolves, it is essential for stakeholders to remain agile and responsive to these trends, ensuring they capitalize on the rapidly changing landscape of gene therapy in Japan.

    Japan Gene Therapy Market Drivers

    Market Segment Insights

    Gene Therapy Market Therapeutic Area Insights

    The Japan Gene Therapy Market is experiencing substantial growth, particularly within its Therapeutic Area segment, which includes Oncology, Genetic Disorders, Infectious Diseases, Cardiovascular Diseases, and Neurological Disorders. This expansion is primarily driven by increasing prevalence rates of chronic diseases and genetic disorders that necessitate innovative treatment solutions; organizations in Japan are at the forefront of research and development in gene therapy. Oncology is a critical focus, as the rising incidences of cancer within the population have intensified the demand for advanced therapeutic alternatives, making it a significant player in the market.

    Genetic Disorders are becoming a prominent area of study and development due to the prevalence of inherited conditions among the Japanese population, which has led to significant investment towards personalized treatment options. Infectious Diseases are also gaining attention within the gene therapy landscape, particularly in combating viral infections and developing long-lasting immune responses. Japan's aging population further increases the relevance of Cardiovascular Diseases, where gene therapy offers new horizons for managing coronary artery disease and heart failure, thus responding to a substantial healthcare burden.

    Neurological Disorders, including conditions like muscular dystrophy and Parkinson's disease, are increasingly targeted by gene therapies, as recent advancements show promise in addressing complex neurological challenges that have traditionally had limited treatment options. The interplay of cutting-edge Research and Development, supportive government initiatives, and rising healthcare expenditure in Japan positions each of these areas as vital components of the overall growth trajectory of the Japan Gene Therapy Market. 

    Continued investment and collaboration among stakeholders will be essential in addressing the unique challenges presented by these therapeutic areas, ultimately leading to improved patient outcomes and a significant impact on Japan's healthcare landscape.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Gene Therapy Market Technology Insights

    The Technology segment of the Japan Gene Therapy Market showcases a variety of innovative modalities, each playing a crucial role in advancing the field of genetic medicine. Viral Vectors, which utilize modified viruses to deliver therapeutic genes, are highly regarded for their efficiency in gene transfer and their ability to target specific cells. CRISPR technology, known for its precision and flexibility, has revolutionized gene editing by allowing targeted modifications in the genome, leading to novel treatments. 

    RNA Therapy, focusing on leveraging RNA molecules for therapeutic effect, represents a dynamic area with significant potential for addressing various genetic disorders.Non-Viral Methods, on the other hand, provide alternative strategies that often pose fewer safety concerns and are vital for developing accessible treatments. The interplay of these technologies fosters a rich landscape in the Japan Gene Therapy Market, driving research, development, and clinical applications. With the rapid advancements in these technologies, opportunities for novel therapies targeting previously untreatable conditions continue to expand, positioning Japan as a crucial player in the global gene therapy arena.

    Gene Therapy Market Application Insights

    The Application segment of the Japan Gene Therapy Market plays a crucial role in shaping the future of healthcare through innovative treatment options. This segment encompasses various aspects, including Research, Clinical, and Commercial applications, which are essential for translating gene therapy discoveries into real-world solutions. The Research component acts as a foundation for advancements in gene editing technologies, with Japan investing significantly in life sciences and biotechnology to foster innovation. Meanwhile, the Clinical aspect focuses on the development of targeted therapies for genetic disorders, where the country's efficient regulatory framework facilitates the approval of novel therapeutics.

    The Commercial arm is emerging as a robust player, largely driven by increasing demand for personalized medicine in Japan, where population aging fuels the necessity for effective treatments. Together, these components contribute to a well-rounded and expanding Japan Gene Therapy Market, creating opportunities for collaboration between academic institutions and industry players. The growth of the market reflects a broader trend towards precision medicine and cutting-edge therapies that promise to enhance patient outcomes across various medical fields.

    Gene Therapy Market Route of Administration Insights

    The Japan Gene Therapy Market is characterized by its diverse Route of Administration, which significantly influences the efficacy and patient compliance associated with therapies. Among the various methods, Intravenous administration is particularly significant due to its rapid delivery into the bloodstream, making it suitable for a range of conditions requiring immediate action. Intramuscular administration, on the other hand, offers a less invasive option and can be important for localized treatments, thereby catering to specific patient needs and preferences.Intradermal routes are increasingly recognized for their utility in vaccines and localized therapies, providing a targeted approach with minimal systemic exposure. 

    The Intrathecal method allows for direct delivery to the central nervous system, making it critical for treating neurological disorders, while oral administration is favored for its patient-friendly approach and ease of use, although it presents challenges related to bioavailability and absorption. The continued evolution of these administration routes, propelled by advancements in technology and increasing demand for gene therapies in Japan, presents numerous opportunities for growth and innovation in the industry.Factors such as population aging and increasing prevalence of genetic disorders further drive the Japan Gene Therapy Market segmentation, setting the stage for a dynamic future in treatment options.

    Get more detailed insights about Japan Gene Therapy Market Research Report - Forecast to 2035

    Regional Insights

    Key Players and Competitive Insights

    The Japan Gene Therapy Market is experiencing significant growth and transformation, driven by advancements in biotechnology and a rising demand for innovative treatments for genetic disorders and chronic diseases. The competitive landscape in this market is characterized by both established pharmaceutical companies and emerging biotech firms that are actively developing and commercializing gene therapy products. A range of factors influences competition, including the regulatory environment, technological advancements, and collaborations among industry players. 

    Companies in this sector are increasingly focused on enhancing their product pipelines, investing in clinical trials, and forging strategic partnerships to gain a competitive edge in the rapidly evolving landscape of gene therapy in Japan.BristolMyers Squibb is a formidable player in the Japan Gene Therapy Market, leveraging its strong research and development capabilities to deliver innovative gene therapies that address critical unmet medical needs. The company has established its presence in Japan through a robust portfolio of products that not only cater to the local market but also align with global standards of excellence.

    BristolMyers Squibb's emphasis on collaboration with local research institutions and healthcare providers has enabled it to gain valuable insights into the unique genetic landscape of the Japanese population. 

    Furthermore, the company's commitment to patient-centric solutions and its expertise in navigating regulatory pathways position it as a trusted name in the gene therapy space in Japan, driving its competitive advantage.Genetzis, a dynamic entity in the Japan Gene Therapy Market, is recognized for its pioneering work in the field of genetic applications and therapies. The company has successfully developed a range of key products aimed at treating genetic disorders. Genetzis distinguishes itself through its innovative technology platforms and a focus on personalized gene therapies that cater specifically to the needs of Japanese patients. 

    The firm's strategic partnerships and collaborations with academic and research institutions have facilitated its growth and established its reputation within the market. Genetzis has also pursued mergers and acquisitions to expand its capabilities and accelerate the development of its gene therapy portfolio. With an intent to improve efficacy and patient outcomes, Genetzis continues to invest in cutting-edge research, further solidifying its position in the gene therapy landscape of Japan.

    Key Companies in the Japan Gene Therapy Market market include

    Industry Developments

    Japan's Gene Therapy Market is witnessing substantial advancements, highlighted by the continuous efforts of companies like Bristol Myers Squibb, Genetzis, Pfizer, and Astellas Pharma. In recent times, notable progress has been made in the approval and commercialization of gene therapies, particularly for rare genetic disorders. In October 2023, Bristol Myers Squibb announced a significant partnership with Takeda Pharmaceutical to enhance their gene therapy capabilities. 

    Moreover, there have been growing investments in Research and Development; Novartis and Roche have declared further investments aimed at expanding their gene therapy offerings in Japan.In terms of mergers and acquisitions, Genetzis acquired a stake in a leading biopharmaceutical firm in September 2023, further consolidating its position in the market. The Japanese government is emphasizing gene therapy as a crucial element of its healthcare strategy, allocating resources to support innovation in this area, which is expected to propel growth. 

    The market valuation for gene therapies in Japan has been increasing, reflecting a rising demand for advanced treatment options, significantly impacting patient care outcomes and the broader healthcare landscape. The increasing focus on genetically targeted therapies also indicates a shift toward personalized medicine in Japan's healthcare system.

    Market Segmentation

    Outlook

    • Intravenous
    • Intramuscular
    • Intradermal
    • Intrathecal
    • Oral

    Gene Therapy Market Technology Outlook

    • Viral Vectors
    • CRISPR
    • Gene Editing
    • RNA Therapy
    • Non-Viral Methods

    Gene Therapy Market Application Outlook

    • Research
    • Clinical
    • Commercial

    Gene Therapy Market Therapeutic Area Outlook

    • Oncology
    • Genetic Disorders
    • Infectious Diseases
    • Cardiovascular Diseases
    • Neurological Disorders

    Gene Therapy Market Route of Administration Outlook

    • Intravenous
    • Intramuscular
    • Intradermal
    • Intrathecal
    • Oral

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2023 193.5(USD Million)
    MARKET SIZE 2024 218.1(USD Million)
    MARKET SIZE 2035 872.4(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 13.431% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Million
    KEY COMPANIES PROFILED BristolMyers Squibb, Genetzis, Pfizer, Sangamo Therapeutics, CRISPR Therapeutics, UniQure, Roche, bluebird bio, Voyager Therapeutics, Astellas Pharma, Genoa, AbbVie, Novartis, Mitsubishi Tanabe Pharma, Takeda Pharmaceutical
    SEGMENTS COVERED Therapeutic Area, Technology, Application, Route of Administration
    KEY MARKET OPPORTUNITIES Increasing prevalence of rare diseases, Growing investment in research and development, Advancements in delivery methods, Expanding regulatory support and frameworks, Rising demand for personalized medicine
    KEY MARKET DYNAMICS regulatory approvals and guidelines, increasing investment in R&D, rising prevalence of genetic disorders, advancements in delivery technologies, supportive governmental policies
    COUNTRIES COVERED Japan

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the expected market size of the Japan Gene Therapy Market for the year 2024?

    The Japan Gene Therapy Market is expected to be valued at 218.1 million USD in 2024.

    What is the projected market value of the Japan Gene Therapy Market by 2035?

    By 2035, the Japan Gene Therapy Market is anticipated to reach a valuation of 872.4 million USD.

    What is the expected compound annual growth rate (CAGR) for the Japan Gene Therapy Market from 2025 to 2035?

    The expected CAGR for the Japan Gene Therapy Market from 2025 to 2035 is 13.431%.

    Which therapeutic area is expected to dominate the Japan Gene Therapy Market in 2024?

    Oncology is expected to dominate the Japan Gene Therapy Market with a valuation of 72.0 million USD in 2024.

    How much is the market for genetic disorders in the Japan Gene Therapy Market projected to be worth in 2035?

    The market for genetic disorders is projected to be worth 200.0 million USD in 2035.

    Who are the key players in the Japan Gene Therapy Market?

    Major players in the Japan Gene Therapy Market include BristolMyers Squibb, Genetzis, Pfizer, and Roche.

    What is the market size for infectious diseases in the Japan Gene Therapy Market in 2024?

    The market size for infectious diseases in the Japan Gene Therapy Market is valued at 40.0 million USD in 2024.

    What is the expected growth value of the cardiovascular diseases segment in the Japan Gene Therapy Market by 2035?

    The cardiovascular diseases segment is expected to grow to a value of 120.0 million USD by 2035.

    What emerging trends are influencing the Japan Gene Therapy Market?

    Emerging trends in the Japan Gene Therapy Market include advancements in genetic editing technologies and increasing focus on personalized medicine.

    What challenges currently face the Japan Gene Therapy Market?

    Challenges facing the Japan Gene Therapy Market include regulatory hurdles and the high cost of gene therapies.

    1. EXECUTIVE
    2. SUMMARY
    3. Market Overview
    4. Key Findings
    5. Market Segmentation
    6. Competitive Landscape
    7. Challenges and Opportunities
    8. Future Outlook
    9. MARKET INTRODUCTION
    10. Definition
    11. Scope of the study
    12. Research Objective
    13. Assumption
    14. Limitations
    15. RESEARCH
    16. METHODOLOGY
    17. Overview
    18. Data
    19. Mining
    20. Secondary Research
    21. Primary
    22. Research
    23. Primary Interviews and Information Gathering
    24. Process
    25. Breakdown of Primary Respondents
    26. Forecasting
    27. Model
    28. Market Size Estimation
    29. Bottom-Up
    30. Approach
    31. Top-Down Approach
    32. Data
    33. Triangulation
    34. Validation
    35. MARKET
    36. DYNAMICS
    37. Overview
    38. Drivers
    39. Restraints
    40. Opportunities
    41. MARKET FACTOR ANALYSIS
    42. Value chain Analysis
    43. Porter's
    44. Five Forces Analysis
    45. Bargaining Power of Suppliers
    46. Bargaining
    47. Power of Buyers
    48. Threat of New Entrants
    49. Threat
    50. of Substitutes
    51. Intensity of Rivalry
    52. COVID-19
    53. Impact Analysis
    54. Market Impact Analysis
    55. Regional
    56. Impact
    57. Opportunity and Threat Analysis
    58. Japan
    59. Gene Therapy Market, BY Therapeutic Area (USD Million)
    60. Oncology
    61. Genetic
    62. Disorders
    63. Infectious Diseases
    64. Cardiovascular
    65. Diseases
    66. Neurological Disorders
    67. Japan
    68. Gene Therapy Market, BY Technology (USD Million)
    69. Viral
    70. Vectors
    71. CRISPR
    72. Gene Editing
    73. RNA
    74. Therapy
    75. Non-Viral Methods
    76. Japan
    77. Gene Therapy Market, BY Application (USD Million)
    78. Research
    79. Clinical
    80. Commercial
    81. Japan
    82. Gene Therapy Market, BY Route of Administration (USD Million)
    83. Intravenous
    84. Intramuscular
    85. Intradermal
    86. Intrathecal
    87. Oral
    88. Competitive Landscape
    89. Overview
    90. Competitive
    91. Analysis
    92. Market share Analysis
    93. Major
    94. Growth Strategy in the Gene Therapy Market
    95. Competitive
    96. Benchmarking
    97. Leading Players in Terms of Number of Developments
    98. in the Gene Therapy Market
    99. Key developments and growth
    100. strategies
    101. New Product Launch/Service Deployment
    102. Merger
    103. & Acquisitions
    104. Joint Ventures
    105. Major
    106. Players Financial Matrix
    107. Sales and Operating Income
    108. Major
    109. Players R&D Expenditure. 2023
    110. Company
    111. Profiles
    112. BristolMyers Squibb
    113. Financial
    114. Overview
    115. Products Offered
    116. Key
    117. Developments
    118. SWOT Analysis
    119. Key
    120. Strategies
    121. Genetzis
    122. Financial
    123. Overview
    124. Products Offered
    125. Key
    126. Developments
    127. SWOT Analysis
    128. Key
    129. Strategies
    130. Pfizer
    131. Financial
    132. Overview
    133. Products Offered
    134. Key
    135. Developments
    136. SWOT Analysis
    137. Key
    138. Strategies
    139. Sangamo Therapeutics
    140. Financial
    141. Overview
    142. Products Offered
    143. Key
    144. Developments
    145. SWOT Analysis
    146. Key
    147. Strategies
    148. CRISPR Therapeutics
    149. Financial
    150. Overview
    151. Products Offered
    152. Key
    153. Developments
    154. SWOT Analysis
    155. Key
    156. Strategies
    157. UniQure
    158. Financial
    159. Overview
    160. Products Offered
    161. Key
    162. Developments
    163. SWOT Analysis
    164. Key
    165. Strategies
    166. Roche
    167. Financial
    168. Overview
    169. Products Offered
    170. Key
    171. Developments
    172. SWOT Analysis
    173. Key
    174. Strategies
    175. bluebird bio
    176. Financial
    177. Overview
    178. Products Offered
    179. Key
    180. Developments
    181. SWOT Analysis
    182. Key
    183. Strategies
    184. Voyager Therapeutics
    185. Financial
    186. Overview
    187. Products Offered
    188. Key
    189. Developments
    190. SWOT Analysis
    191. Key
    192. Strategies
    193. Astellas Pharma
    194. Financial
    195. Overview
    196. Products Offered
    197. Key
    198. Developments
    199. SWOT Analysis
    200. Key
    201. Strategies
    202. Genoa
    203. Financial
    204. Overview
    205. Products Offered
    206. Key
    207. Developments
    208. SWOT Analysis
    209. Key
    210. Strategies
    211. AbbVie
    212. Financial
    213. Overview
    214. Products Offered
    215. Key
    216. Developments
    217. SWOT Analysis
    218. Key
    219. Strategies
    220. Novartis
    221. Financial
    222. Overview
    223. Products Offered
    224. Key
    225. Developments
    226. SWOT Analysis
    227. Key
    228. Strategies
    229. Mitsubishi Tanabe Pharma
    230. Financial
    231. Overview
    232. Products Offered
    233. Key
    234. Developments
    235. SWOT Analysis
    236. Key
    237. Strategies
    238. Takeda Pharmaceutical
    239. Financial
    240. Overview
    241. Products Offered
    242. Key
    243. Developments
    244. SWOT Analysis
    245. Key
    246. Strategies
    247. References
    248. Related
    249. Reports
    250. LIST
    251. OF ASSUMPTIONS
    252. Japan Gene Therapy Market SIZE ESTIMATES
    253. & FORECAST, BY THERAPEUTIC AREA, 2019-2035 (USD Billions)
    254. Japan
    255. Gene Therapy Market SIZE ESTIMATES & FORECAST, BY TECHNOLOGY, 2019-2035 (USD
    256. Billions)
    257. Japan Gene Therapy Market SIZE ESTIMATES &
    258. FORECAST, BY APPLICATION, 2019-2035 (USD Billions)
    259. Japan
    260. Gene Therapy Market SIZE ESTIMATES & FORECAST, BY ROUTE OF ADMINISTRATION, 2019-2035
    261. (USD Billions)
    262. PRODUCT LAUNCH/PRODUCT DEVELOPMENT/APPROVAL
    263. ACQUISITION/PARTNERSHIP
    264. LIST
    265. Of figures
    266. MARKET SYNOPSIS
    267. JAPAN
    268. GENE THERAPY MARKET ANALYSIS BY THERAPEUTIC AREA
    269. JAPAN
    270. GENE THERAPY MARKET ANALYSIS BY TECHNOLOGY
    271. JAPAN GENE
    272. THERAPY MARKET ANALYSIS BY APPLICATION
    273. JAPAN GENE THERAPY
    274. MARKET ANALYSIS BY ROUTE OF ADMINISTRATION
    275. KEY BUYING
    276. CRITERIA OF GENE THERAPY MARKET
    277. RESEARCH PROCESS OF MRFR
    278. DRO
    279. ANALYSIS OF GENE THERAPY MARKET
    280. DRIVERS IMPACT ANALYSIS:
    281. GENE THERAPY MARKET
    282. RESTRAINTS IMPACT ANALYSIS: GENE
    283. THERAPY MARKET
    284. SUPPLY / VALUE CHAIN: GENE THERAPY MARKET
    285. GENE
    286. THERAPY MARKET, BY THERAPEUTIC AREA, 2025 (% SHARE)
    287. GENE
    288. THERAPY MARKET, BY THERAPEUTIC AREA, 2019 TO 2035 (USD Billions)
    289. GENE
    290. THERAPY MARKET, BY TECHNOLOGY, 2025 (% SHARE)
    291. GENE THERAPY
    292. MARKET, BY TECHNOLOGY, 2019 TO 2035 (USD Billions)
    293. GENE
    294. THERAPY MARKET, BY APPLICATION, 2025 (% SHARE)
    295. GENE THERAPY
    296. MARKET, BY APPLICATION, 2019 TO 2035 (USD Billions)
    297. GENE
    298. THERAPY MARKET, BY ROUTE OF ADMINISTRATION, 2025 (% SHARE)
    299. GENE
    300. THERAPY MARKET, BY ROUTE OF ADMINISTRATION, 2019 TO 2035 (USD Billions)
    301. BENCHMARKING
    302. OF MAJOR COMPETITORS

    Japan Gene Therapy Market Segmentation

    • Gene Therapy Market By Therapeutic Area (USD Million, 2019-2035)

      • Oncology
      • Genetic Disorders
      • Infectious Diseases
      • Cardiovascular Diseases
      • Neurological Disorders
    • Gene Therapy Market By Technology (USD Million, 2019-2035)

      • Viral Vectors
      • CRISPR
      • Gene Editing
      • RNA Therapy
      • Non-Viral Methods
    • Gene Therapy Market By Application (USD Million, 2019-2035)

      • Research
      • Clinical
      • Commercial
    • Gene Therapy Market By Route of Administration (USD Million, 2019-2035)

      • Intravenous
      • Intramuscular
      • Intradermal
      • Intrathecal
      • Oral
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