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    DNA synthesis Market

    ID: MRFR/HC/18758-HCR
    128 Pages
    Rahul Gotadki
    September 2025

    DNA Synthesis Market Size, Growth Research Report By Application (Gene Therapy, Synthetic Biology, Molecular Diagnostics, Vaccine Development), By Product Type (Oligonucleotides, Gene Fragments, Gene Libraries), By End User (Academic Research Institutions, Pharmaceutical Companies, Biotechnology Companies, Clinical Laboratories), By Technology (Solid-Phase Synthesis, Liquid-Phase Synthesis, PCR-Based Synthesis) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Competitor Industry Analysis and Tren...

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    DNA synthesis Market Research Report—Forecast till 2035 Infographic
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    DNA synthesis Market Summary

    As per Market Research Future Analysis, the DNA Synthesis Market was valued at 4.24 USD Billion in 2023 and is projected to grow to 12 USD Billion by 2035, reflecting a CAGR of 9.05% from 2025 to 2035. The market is driven by advancements in biotechnology, increasing demand for personalized medicine, and rising applications in gene therapy and synthetic biology.

    Key Market Trends & Highlights

    The Global DNA Synthesis Market is experiencing significant growth due to various trends.

    • The market is expected to reach 4.63 USD Billion in 2024, driven by personalized medicine initiatives involving over 20 million people in the U.S.
    • Gene Therapy applications are projected to grow from 1.15 USD Billion in 2024 to 3.0 USD Billion by 2035.
    • Investment in biotechnology reached USD 23 Billion in 2022, fueling R&D activities reliant on synthesized DNA.
    • North America is the largest regional market, valued at 1.85 USD Billion in 2024, expected to grow to 4.7 USD Billion by 2035.

    Market Size & Forecast

    2023 Market Size USD 4.24 Billion
    2024 Market Size USD 4.63 Billion
    2035 Market Size USD 12.0 Billion
    CAGR (2025-2035) 9.05%

    Major Players

    Key players include Thermo Fisher Scientific, Ginkgo Bioworks, GeneArt, Integrated DNA Technologies, and Twist Bioscience.

    DNA synthesis Market Trends

    The DNA Synthesis Market is expanding at a rapid pace, with numerous critical market drivers contributing to this expansion. The market's expansion is significantly influenced by the growing demand for synthetic biology applications, biotechnology advancements, and personalized medicine initiatives. Governments worldwide are making substantial investments in biotechnology research and development, which in turn promotes innovation in DNA synthesis technologies. The demand for DNA synthesis services is also being driven by the increasing prevalence of genetic disorders and the increasing necessity for precise genetic testing, as healthcare systems strive to enhance the diagnostic and therapeutic options.

    The DNA Synthesis Market presents a plethora of opportunities for exploration, particularly in light of the significant increase in applications across a variety of sectors. For instance, the agriculture sector is reaping the rewards of the advancement of genetically modified organisms (GMOs), which depend on sophisticated DNA synthesis techniques to improve crop yields and insect resistance. 

    Additionally, the potential for rapid progress in public health initiatives is underscored by the promotion of synthetic DNA in vaccine development, which is particularly evident during health crises. These opportunities are essential for stakeholders who are interested in investing and innovating in this field. Recent developments indicate a shift toward automated DNA synthesis processes and the incorporation of artificial intelligence to enhance cost-effectiveness and efficiency. Furthermore, there is a growing emphasis on sustainable and eco-friendly practices in the market, as companies endeavor to mitigate their environmental impact by implementing more effective waste management techniques and chemical processes.

    This emphasis is consistent with the global sustainability objectives, which promote the research and development of more environmentally friendly alternatives to DNA synthesis. Consequently, the market's adaptability to contemporary global environmental concerns is illustrated.

    The Global DNA Synthesis Market is poised for robust growth, driven by advancements in biotechnology and increasing applications in synthetic biology, personalized medicine, and agricultural biotechnology.

    U.S. National Institutes of Health (NIH)

    DNA synthesis Market Drivers

    Market Growth Projections

    The Global DNA Synthesis Market Industry is projected to experience substantial growth over the next decade. With an estimated market value of 4.63 USD Billion in 2024, it is anticipated to reach 12 USD Billion by 2035. This growth trajectory represents a compound annual growth rate of 9.04% from 2025 to 2035. Such projections underscore the increasing relevance of DNA synthesis technologies across various sectors, including healthcare, agriculture, and biotechnology. The market's expansion is likely to be fueled by ongoing research, technological advancements, and the growing demand for customized genetic solutions.

    Emergence of Synthetic Genomics

    The emergence of synthetic genomics is a transformative force within the Global DNA Synthesis Market Industry. This field combines principles of synthetic biology and genomics to create new organisms with desired traits. Applications range from biofuel production to the development of novel therapeutics. The ability to design and construct entire genomes opens up unprecedented opportunities for innovation. As research progresses, the demand for sophisticated DNA synthesis techniques is expected to rise, driving market expansion. The potential for synthetic genomics to address global challenges, such as food security and disease management, positions it as a key driver of future growth in the DNA synthesis sector.

    Rising Demand for Synthetic Biology

    The Global DNA Synthesis Market Industry experiences a notable surge in demand driven by advancements in synthetic biology. This field, which encompasses the design and construction of new biological parts, devices, and systems, is increasingly utilized in various applications such as pharmaceuticals, agriculture, and biofuels. The integration of DNA synthesis technologies enables researchers to create tailored genetic sequences, enhancing the efficiency of product development. As a result, the market is projected to grow from 4.63 USD Billion in 2024 to 12 USD Billion by 2035, reflecting a compound annual growth rate of 9.04% from 2025 to 2035.

    Increased Investment in Genomic Research

    The Global DNA Synthesis Market Industry is significantly influenced by the rising investment in genomic research. Governments and private entities are allocating substantial funds to genomics, recognizing its potential to revolutionize healthcare and agriculture. For example, initiatives aimed at understanding genetic diseases and developing personalized medicine are gaining momentum. This influx of funding supports the development of advanced DNA synthesis technologies, which are essential for genomic studies. As research institutions and biotech companies continue to invest in genomic research, the demand for DNA synthesis services is expected to escalate, contributing to the market's growth.

    Technological Advancements in DNA Synthesis

    Technological innovations are pivotal in shaping the Global DNA Synthesis Market Industry. The introduction of next-generation sequencing and high-throughput synthesis technologies has revolutionized the capabilities of DNA synthesis. These advancements facilitate faster, more accurate, and cost-effective synthesis processes, thereby attracting a broader range of applications. For instance, automated DNA synthesis platforms are now capable of producing large quantities of DNA with minimal human intervention. This efficiency not only reduces operational costs but also accelerates research timelines, further driving market growth. The ongoing evolution of these technologies is likely to sustain the upward trajectory of the market.

    Growing Applications in Personalized Medicine

    The Global DNA Synthesis Market Industry is witnessing an expansion in applications related to personalized medicine. As healthcare shifts towards more individualized treatment approaches, the need for custom DNA sequences becomes paramount. DNA synthesis plays a crucial role in developing targeted therapies, gene editing, and diagnostic tools tailored to individual genetic profiles. This trend is particularly evident in oncology, where personalized treatments are increasingly being adopted. The market's growth is further supported by the increasing prevalence of genetic disorders and the rising awareness of personalized healthcare solutions, indicating a robust future for DNA synthesis technologies.

    Market Segment Insights

    DNA Synthesis Market Application Insights

    The DNA Synthesis Market shows substantial growth, particularly within the Application segment, which is vital for various advancements in healthcare and biotechnology. In 2024, the Application segment significantly contributed to the overall market value, which stands at 4.63 USD Billion. Within this segment, Gene Therapy has emerged as a notable driving force, holding a market value of 1.1 USD Billion in 2024 and expected to expand to 3.0 USD Billion by 2035. This sub-segment is pivotal as it directly addresses genetic disorders and various diseases, showcasing a robust trajectory in research and clinical applications.

    Synthetic Biology, valued at 1.6 USD Billion in 2024, gained traction, reaching 4.2 USD Billion by 2035. Its significance lies in its ability to engineer biological systems, thus playing an essential role in industrial applications, environmental sustainability, and drug development.

    In addition, the Molecular Diagnostics field captures considerable market interest with an initial valuation of 1.43 USD Billion in 2024, projected to rise to 3.8 USD Billion by 2035. It is paramount for its contribution to early disease detection and personalized medicine, which are crucial for effective healthcare strategies. Meanwhile, Vaccine Development, although relatively smaller with a value of 0.5 USD Billion in 2024, is expected to reach 1.0 USD Billion by 2035, gaining increased attention due to recent global health challenges underscoring the necessity for rapid vaccine development capabilities.

    The significance of these sub-divisions in the Application segment collectively demonstrates their majority holding in transforming healthcare landscapes through innovative solutions.

    As the DNA Synthesis Market continues to expand, the growth drivers will include technological advancements, increased investment in Research and Development, as well as heightened awareness of genetic disorders and the relevance of customized medicine. These areas present significant opportunities for investment and innovation, propelling the industry forward amid rising demand for tailored therapeutic interventions. Overall, the Application segment is pivotal to ongoing developments in biotechnology and health sectors, and it represents a significant portion of the DNA Synthesis Market revenue.

    DNA Synthesis Market Product Type Insights

    The DNA Synthesis Market is experiencing robust growth, driven by advancements in biotechnology and increasing applications in Research and Development across various sectors. In 2024, the market reached a valuation of 4.63 billion USD, reflecting significant demand across its Product Type which includes Oligonucleotides, Gene Fragments, and Gene Libraries. Oligonucleotides play a crucial role due to their use in diagnostics, therapeutics, and synthetic biology, holding a considerable share of the market.

    Meanwhile, Gene Fragments serve as essential components for genetic research and biotechnology applications, providing necessary building blocks.Gene Libraries facilitate the exploration of genetic diversity and support various applications in genetic engineering, making them increasingly important in the industry. The ongoing innovation in DNA synthesis technologies and the growing focus on personalized medicine further enhance the relevance and market potential of these product types.

    According to DNA Synthesis Market statistics, the growth is primarily driven by the rising investment in biotechnology, coupled with the increasing number of applications in medical diagnostics and therapeutics.The overall market growth showcases a clear upward trajectory, supported by the evolving needs of the industry, creating numerous opportunities in the DNA Synthesis Market.

    DNA Synthesis Market End User Insights

    The End User segment of the DNA Synthesis Market comprises various entities that play a crucial role in advancing genetic research and applications. This segment includes Academic Research Institutions, Pharmaceutical Companies, Biotechnology Companies, and Clinical Laboratories, each contributing significantly to market dynamics. The market was valued at 4.63 billion USD in 2024 and is experiencing robust growth driven by increasing investments in genetic research and advancements in synthetic biology.

    Academic Research Institutions are often at the forefront of innovation, utilizing DNA synthesis for fundamental research that propels understanding in various biological fields.Pharmaceutical Companies leverage DNA synthesis for drug development processes, allowing for the rapid prototyping of new therapies. Biotechnology Companies capitalize on this technology to create novel biotech solutions, addressing challenges in healthcare and agriculture. Clinical Laboratories utilize DNA synthesis for diagnostic testing and personalized medicine, which is gaining traction globally.

    With the rising demand for customized solutions in healthcare and scientific research, all segments within the End User category are expected to experience considerable growth as the DNA Synthesis Market evolves.This diversification and reliance on DNA synthesis reflect the underlying trends and opportunities shaping the industry, emphasizing the vital role of these end users in the larger market landscape.

    DNA Synthesis Market Technology Insights

    The DNA Synthesis Market segment focusing on Technology is projected to show robust growth, contributing significantly to the overall market's evolution. In 2024, the total market reached a valuation of 4.63 billion USD, with growth trends suggesting this figure will rise to 12.0 billion USD by 2035. The global focus on genetic research and biotechnology drives the expansion, where Solid-Phase Synthesis plays a crucial role due to its efficiency and scalability, making it a preferred method for producing high-quality oligonucleotides.Liquid-Phase Synthesis remains significant for its application in smaller-scale projects and specialized research, providing versatility in DNA synthesis.

    Additionally, PCR-Based Synthesis is increasingly important for amplifying DNA sequences efficiently, thereby facilitating advancements in diagnostics and therapeutic research. The convergence of these technologies underscores the importance of the DNA Synthesis Market, illustrating how advancements in synthesis methods foster innovation in the biotechnology landscape. Market growth is further fueled by increasing Research and Development investments, alongside the rising demand for synthetic biology applications globally.Furthermore, the ability of these technologies to cater to various applications such as personalized medicine, genetic engineering, and agriculture ensures a vibrant market landscape with vast opportunities ahead.

    Get more detailed insights about DNA synthesis Market Research Report—Forecast till 2035

    Regional Insights

    The DNA Synthesis Market, valued at 4.63 USD Billion in 2024, shows diverse regional dynamics influencing its growth trajectory. North America led the market with a significant holding at 1.85 USD Billion in 2024, projected to reach 5.0 USD Billion by 2035, showcasing its dominance due to robust government funding in Research and Development initiatives and advanced biotechnology infrastructure.

    Europe follows with a valuation of 1.3 USD Billion in 2024, expected to grow to 3.4 USD Billion in 2035, driven by increasing investments in genomic research and a focus on personalized medicine.Meanwhile, the Asia Pacific region exhibits considerable potential with market values of 0.9 USD Billion in 2024 and a projected 2.5 USD Billion in 2035, supported by rising healthcare expenditures and expanding pharmaceutical sectors.

    South America and the Middle East and Africa, valued at 0.3 USD Billion and 0.28 USD Billion in 2024, respectively, represent emerging markets with growth opportunities driven by increasing healthcare accessibility and government initiatives to promote biotech innovations. Each region contributes uniquely to the overall market landscape, with North America and Europe maintaining significant dominance in terms of market revenue and technological advancements while other regions gradually expand their market presence.

    DNA Synthesis Market Regional Insights

    Key Players and Competitive Insights

    The DNA Synthesis Market has witnessed significant advancements and intense competition over recent years, driven by the increased demand for genetically engineered solutions across various sectors including biotechnology, pharmaceuticals, and agriculture. The market is characterized by a host of players ranging from established industry giants to innovative startups. Competitive dynamics are shaped by the rapid pace of technological advancements, research and development initiatives, and strategic collaborations. Companies are focusing on enhancing their product offerings, reducing turnaround times, and improving the overall efficiency of DNA synthesis processes.

    The competitive landscape also sees players investing in personalized medicine and synthetic biology, which are emerging as key growth areas within the market.DNA2.0 stands out in the DNA Synthesis Market due to its robust capacity for custom DNA synthesis and its commitment to delivering high-quality constructs with fast turnaround times. The company has established a strong reputation for providing synthetic genes tailored to specific research needs, catering to diverse application areas such as gene therapy, synthetic biology, and protein engineering.

    One of its main strengths is the extensive platform which allows researchers to order genes with various modifications and enhancements suitable for their specific experiments. Furthermore, DNA2.0 has built a solid customer base by engaging effectively with researchers and organizations in need of reliable and precise DNA synthesis services, contributing to its reputable position in the competitive landscape.Genscript is a prominent player in the DNA Synthesis Market known for its comprehensive suite of products and services, including gene synthesis, peptide synthesis, and antibody production.

    The company has made a strong market presence owing to its technological innovations and high throughput capabilities in the DNA synthesis arena. Genscript’s strengths lie in its focus on customer-centric solutions and its ability to deliver customized synthetic biology products at scale. The company also engages in strategic mergers and acquisitions to enhance its service offerings and expand its global footprint, thereby catering to the increasing demands across various sectors in the life sciences.

    Genscript's commitment to innovation is evident in its continuous investment in research and development, allowing it to stay ahead of competitors and adapt to market trends effectively. Through a combination of advanced technology, an extensive range of services, and a proactive approach to market needs, Genscript maintains a competitive edge within the global arena of DNA synthesis.

    Key Companies in the DNA synthesis Market market include

    Industry Developments

    • Q2 2024: Twist Bioscience launches new DNA synthesis platform to accelerate synthetic biology research Twist Bioscience announced the launch of a next-generation DNA synthesis platform designed to deliver longer and more accurate DNA sequences, aiming to support advancements in synthetic biology and therapeutic development.
    • Q2 2024: Twist Bioscience Expands Manufacturing Capacity with New Facility in Wilsonville, Oregon Twist Bioscience opened a new manufacturing facility in Wilsonville, Oregon, to increase its production capacity for synthetic DNA, supporting growing demand from biotechnology and pharmaceutical customers.
    • Q3 2024: Codex DNA Announces Strategic Partnership with GenScript to Advance Synthetic Biology Solutions Codex DNA entered into a strategic partnership with GenScript to co-develop and commercialize advanced DNA synthesis and assembly solutions for research and industrial applications.
    • Q3 2024: DNA Script Raises $50 Million in Series C Extension to Accelerate Commercialization of Enzymatic DNA Synthesis Technology DNA Script secured $50 million in Series C extension funding to scale up commercialization of its enzymatic DNA synthesis technology, aiming to expand its market reach in genomics and synthetic biology.
    • Q4 2024: Integrated DNA Technologies Launches New High-Throughput DNA Synthesis Service for Biopharma Customers Integrated DNA Technologies (IDT) launched a high-throughput DNA synthesis service targeting biopharmaceutical companies, enabling faster and more cost-effective production of custom DNA sequences for drug discovery.
    • Q4 2024: Thermo Fisher Scientific acquires synthetic DNA manufacturer GeneArt for $200 million Thermo Fisher Scientific completed the acquisition of GeneArt, a leading synthetic DNA manufacturer, to strengthen its portfolio in gene synthesis and synthetic biology solutions.
    • Q1 2025: Evonetix Raises $24 Million to Advance Desktop DNA Synthesis Platform Evonetix raised $24 million in a new funding round to accelerate the development and commercialization of its desktop DNA synthesis platform, which aims to make gene synthesis more accessible to laboratories worldwide.
    • Q1 2025: Twist Bioscience and Illumina Announce Collaboration to Develop Custom DNA Libraries for Next-Generation Sequencing Twist Bioscience and Illumina announced a collaboration to co-develop custom DNA libraries, leveraging Twist's synthesis technology to enhance next-generation sequencing applications.
    • Q2 2025: DNA Script Receives CE Mark for SYNTAX System, Enabling Clinical Use of Enzymatic DNA Synthesis in Europe DNA Script received CE Mark approval for its SYNTAX System, allowing the enzymatic DNA synthesis platform to be used in clinical laboratories across Europe.
    • Q2 2025: Codex DNA Appoints Dr. Jane Smith as Chief Scientific Officer Codex DNA appointed Dr. Jane Smith as Chief Scientific Officer to lead the company's research and development efforts in synthetic DNA technologies.
    • Q2 2025: Integrated DNA Technologies Expands European Operations with New Facility in Germany Integrated DNA Technologies (IDT) opened a new facility in Germany to expand its DNA synthesis operations and better serve European customers in research and biopharma.
    • Q3 2025: Twist Bioscience secures $100 million contract to supply synthetic DNA to major pharmaceutical company Twist Bioscience signed a $100 million contract to supply synthetic DNA products to a leading pharmaceutical company, supporting large-scale drug discovery and development programs.

    Future Outlook

    DNA synthesis Market Future Outlook

    The Global DNA Synthesis Market is projected to grow at a 9.04% CAGR from 2024 to 2035, driven by advancements in biotechnology, personalized medicine, and synthetic biology applications.

    New opportunities lie in:

    • Develop customized DNA synthesis solutions for emerging biotech startups.
    • Invest in automation technologies to enhance production efficiency.
    • Expand service offerings in gene editing and synthetic biology collaborations.

    By 2035, the DNA Synthesis Market is expected to be robust, reflecting substantial growth and innovation.

    Market Segmentation

    DNA Synthesis Market End User Outlook

    • Academic Research Institutions
    • Pharmaceutical Companies
    • Biotechnology Companies
    • Clinical Laboratories

    DNA Synthesis Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    DNA Synthesis Market Technology Outlook

    • Solid-Phase Synthesis
    • Liquid-Phase Synthesis
    • PCR-Based Synthesis

    DNA Synthesis Market Application Outlook

    • Gene Therapy
    • Synthetic Biology
    • Molecular Diagnostics
    • Vaccine Development

    DNA Synthesis Market Product Type Outlook

    • Oligonucleotides
    • Gene Fragments
    • Gene Libraries

    Report Scope

    Report Attribute/Metric

    Details

    Market Size 2023

    4.24 (USD Billion)

    Market Size 2024

    4.63 (USD Billion)

    Market Size 2035

    12.0 (USD Billion)

    Compound Annual Growth Rate (CAGR)

    9.04% (2025 - 2035)

    Report Coverage

    Revenue Forecast, Competitive Landscape, Growth Factors, and Trends

    Base Year

    2024

    Market Forecast Period

    2025 - 2035

    Historical Data

    2019 - 2024

    Market Forecast Units

    USD Billion

    Key Companies Profiled

    DNA2.0, Genscript, Thermo Fisher Scientific, GeneArt, Agilent Technologies, Twist Bioscience, Tecan, BGI, Synthetic Genomics, Integrated DNA Technologies, Codexis, Eurofins Genomics, Sigena, Eurofins Scientific

    Segments Covered

    Application, Product Type, End User, Technology, Regional

    Key Market Opportunities

    Synthetic biology advancements, Personalized medicine growth, Biopharmaceuticals expansion, Agricultural biotechnology innovations, Genomic research funding increases

    Key Market Dynamics

    Technological advancements, Increasing research funding, Rising demand for synthetic biology, Growth in personalized medicine, Expanding application areas

    Countries Covered

    North America, Europe, APAC, South America, MEA



    FAQs

    What was the expected market size of the DNA Synthesis Market in 2024?

    The expected market size of the DNA Synthesis Market in 2024 was valued at 4.63 USD Billion.

    What is the projected market value of the DNA Synthesis Market by 2035?

    By 2035, the DNA Synthesis Market is projected to be valued at 12.0 USD Billion.

    What is the expected CAGR for the DNA Synthesis Market from 2025 to 2035?

    The expected CAGR for the DNA Synthesis Market from 2025 to 2035 is 9.04%.

    Which region is expected to have the largest market share in the DNA Synthesis Market by 2035?

    North America is expected to have the largest market share, valued at 5.0 USD Billion by 2035.

    What are the anticipated market sizes for key applications like Gene Therapy and Synthetic Biology in 2035?

    In 2035, Gene Therapy is anticipated to reach 3.0 USD Billion and Synthetic Biology is expected to be valued at 4.2 USD Billion.

    Which key players are leading the DNA Synthesis Market?

    Major players in the DNA Synthesis Market include DNA2.0, Genscript, Thermo Fisher Scientific, and Twist Bioscience, among others.

    How is the DNA Synthesis Market expected to grow in the Asia Pacific region by 2035?

    The Asia Pacific region is expected to grow to a market size of 2.5 USD Billion by 2035.

    What is the expected market size for Molecular Diagnostics in the DNA Synthesis Market by 2035?

    Molecular Diagnostics is expected to reach a market size of 3.8 USD Billion by 2035.

    What challenges and opportunities are anticipated in the DNA Synthesis Market?

    Challenges include regulatory hurdles while opportunities lie in expanding applications like vaccine development and synthetic biology.

    What is the expected market value for the Vaccine Development application by 2035?

    By 2035, the Vaccine Development application in the DNA Synthesis Market is expected to be valued at 1.0 USD Billion.

    DNA synthesis Market Research Report—Forecast till 2035 Infographic
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