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    US Oncology Drugs Market

    ID: MRFR/Pharma/13148-HCR
    128 Pages
    Rahul Gotadki
    October 2025

    U.S. Oncology Drugs Market Research Report Information By Type (Chemotherapy, Targeted Therapy, Immunotherapy (Biologic Therapy), Hormonal Therapy, Other), By Application (Blood Cancer, Breast Cancer, Gastrointestinal Cancer, Prostate Cancer, Respiratory or Lung Cancer, Other)–Market Forecast Till 2035

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    US Oncology Drugs Market Infographic
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    US Oncology Drugs Market Summary

    As per MRFR analysis, the US oncology drugs market size was estimated at 40.29 USD Billion in 2024. The US oncology drugs market is projected to grow from 46.01 USD Billion in 2025 to 173.63 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 14.2% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The US oncology drugs market is experiencing robust growth driven by innovative therapies and increasing healthcare investments.

    • Immunotherapy continues to rise as a leading treatment modality, reshaping cancer care.
    • Targeted therapies are advancing rapidly, offering more personalized treatment options for patients.
    • Investment in oncology research is increasing, reflecting a commitment to developing new therapies.
    • The growing incidence of cancer and advancements in precision medicine are key drivers of market expansion.

    Market Size & Forecast

    2024 Market Size 40.29 (USD Billion)
    2035 Market Size 173.63 (USD Billion)

    Major Players

    Roche (CH), Bristol Myers Squibb (US), Merck & Co (US), Novartis (CH), Pfizer (US), AstraZeneca (GB), Johnson & Johnson (US), Amgen (US), Gilead Sciences (US)

    US Oncology Drugs Market Trends

    The oncology drugs market is currently experiencing a dynamic evolution, driven by advancements in research and development, as well as an increasing understanding of cancer biology. Innovative therapies, including targeted treatments and immunotherapies, are gaining traction, offering new hope for patients with various cancer types. Regulatory bodies are actively facilitating the approval process for novel drugs, which may lead to a more rapid introduction of effective therapies into the market. Furthermore, the growing emphasis on personalized medicine is reshaping treatment paradigms, allowing for tailored approaches that enhance patient outcomes. In addition, The market is witnessing a surge in investment from both public and private sectors. This influx of funding is likely to accelerate the development of cutting-edge therapies and expand access to existing treatments. The collaboration between pharmaceutical companies and academic institutions appears to be fostering innovation, resulting in a robust pipeline of potential therapies. As the landscape continues to evolve, stakeholders must remain vigilant to adapt to emerging trends and challenges, ensuring that advancements translate into tangible benefits for patients and healthcare systems alike.

    Rise of Immunotherapy

    Immunotherapy is becoming a cornerstone in cancer treatment, leveraging the body's immune system to combat malignancies. This approach is showing promise in various cancer types, leading to improved survival rates and reduced side effects compared to traditional therapies.

    Targeted Therapy Advancements

    Targeted therapies are gaining prominence, focusing on specific genetic mutations and pathways involved in cancer progression. This precision medicine approach is likely to enhance treatment efficacy and minimize adverse effects, aligning with the trend towards personalized healthcare.

    Increased Investment in Research

    Investment in oncology research is on the rise, driven by both public and private sectors. This financial support is expected to accelerate the development of innovative therapies, expand clinical trials, and ultimately improve patient access to cutting-edge treatments.

    US Oncology Drugs Market Drivers

    Growing Cancer Incidence

    The market is experiencing a notable surge due to the increasing incidence of cancer in the United States. According to the American Cancer Society, approximately 1.9 million new cancer cases are expected to be diagnosed in 2025. This rising trend in cancer cases necessitates the development and availability of effective oncology drugs, thereby driving market growth. The market is likely to expand as healthcare providers seek innovative treatments to address this growing patient population. Furthermore, the aging population, which is more susceptible to various cancers, contributes to this upward trajectory. As a result, pharmaceutical companies are focusing on research and development to create targeted therapies and immunotherapies, which are anticipated to dominate the oncology drugs market in the coming years.

    Emerging Biotech Companies

    The oncology drugs market is witnessing a surge in the number of emerging biotech companies focused on developing innovative cancer therapies. These companies are often at the forefront of research, utilizing cutting-edge technologies such as gene editing and artificial intelligence to create novel treatments. The presence of these startups fosters a competitive landscape, driving established pharmaceutical companies to enhance their research and development efforts. In 2025, the oncology drugs market is likely to benefit from the influx of new entrants, which may lead to breakthroughs in treatment options. Furthermore, collaborations between biotech firms and larger pharmaceutical companies are becoming increasingly common, facilitating the sharing of resources and expertise, ultimately accelerating the development of effective oncology drugs.

    Increased Healthcare Expenditure

    The oncology drugs market is positively impacted by the rising healthcare expenditure in the United States. As healthcare spending continues to grow, more resources are allocated towards cancer treatment and research. According to the Centers for Medicare & Medicaid Services, national health expenditure is projected to reach $6.2 trillion by 2028, with a significant portion dedicated to oncology. This increase in funding allows for the development of new oncology drugs and the expansion of treatment options available to patients. Additionally, higher healthcare spending facilitates access to advanced therapies, which may lead to improved patient outcomes. Consequently, The market is expected to thrive as financial resources become more readily available for cancer care.

    Advancements in Precision Medicine

    The oncology drugs market is significantly influenced by advancements in precision medicine, which tailors treatment based on individual patient characteristics. This approach has gained traction in recent years, leading to the development of targeted therapies that are more effective and have fewer side effects. The National Cancer Institute indicates that precision medicine has the potential to improve treatment outcomes for patients with specific genetic mutations. As a result, pharmaceutical companies are investing heavily in research to identify biomarkers and develop drugs that can specifically target these mutations. This trend is expected to enhance the oncology drugs market, as more personalized treatment options become available, ultimately improving patient survival rates and quality of life.

    Regulatory Support for Drug Approvals

    The oncology drugs market benefits from robust regulatory support aimed at expediting the approval process for new cancer therapies. The U.S. Food and Drug Administration (FDA) has implemented various initiatives, such as the Breakthrough Therapy designation, which allows for faster development and review of drugs that show promise in treating serious conditions. This regulatory environment encourages pharmaceutical companies to invest in oncology drug development, as they can bring innovative treatments to market more quickly. In 2025, the oncology drugs market is likely to see an influx of new therapies, as the FDA continues to prioritize cancer treatments. This supportive framework not only fosters innovation but also enhances patient access to potentially life-saving medications.

    Market Segment Insights

    By Type: Chemotherapy Drugs (Largest) vs. Immunotherapy Drugs (Fastest-Growing)

    In the US oncology drugs market, Chemotherapy Drugs constitute the largest segment, commanding a significant share. These drugs play a critical role in the treatment of various cancers, contributing to their widespread usage across different patient populations. On the other hand, Immunotherapy Drugs, though currently smaller in market share, have been rapidly gaining traction due to their innovative approach in harnessing the immune system to fight cancer, marking a notable shift in treatment strategies. Growth trends in the segment are driven by advances in drug development and increasing investment in oncology research. The rising incidence of cancer among the population, coupled with a shift toward personalized medicine, has fueled demand for both Chemotherapy and Immunotherapy Drugs. While Chemotherapy remains essential for aggressive cancer treatment, Immunotherapy is emerging as a vital option for long-term survival and improved quality of life, highlighting the evolving landscape of oncology therapeutics.

    Chemotherapy Drugs (Dominant) vs. Targeted Therapy Drugs (Emerging)

    Chemotherapy Drugs have been the foundation of cancer treatment for decades, showcasing their dominance in the oncology landscape. These drugs, typically used in aggressive interventions, target rapidly dividing cancer cells, thus playing a vital role in various treatment regimens. While they present significant side effects, their effectiveness in shrinking tumors has solidified their presence in standard care. Conversely, Targeted Therapy Drugs represent an emerging trend, focusing on specific cancer cell characteristics. This precision approach minimizes harm to healthy cells, potentially reduces side effects, and enhances efficacy. As research advances, the integration of targeted therapies into treatment protocols is expected to grow, reflecting a shift towards more personalized cancer management.

    By Therapeutic Area: Breast Cancer (Largest) vs. Lung Cancer (Fastest-Growing)

    In the US oncology drugs market, breast cancer remains the largest segment, commanding a significant market share due to extensive research, high patient prevalence, and innovative treatment options, including targeted therapies and immunotherapies. Following closely is the lung cancer segment, which, while smaller, showcases rapid growth as advancements in personalized medicine and early detection methods gain traction. The prioritization of lung cancer research in recent years is gradually escalating its share in the market. The growth trends for these therapeutic areas are driven by factors such as increasing incidence rates, enhanced clinical trial outcomes, and the introduction of novel therapies. For breast cancer, the consistent development of improvements in medication regimens is keeping treatment options broad and effective. In contrast, lung cancer is experiencing robust growth as a result of rising awareness and screening programs, which are expected to increase the number of patients diagnosed and treated effectively. This dynamic landscape suggests that while breast cancer continues to lead, the opportunities within lung cancer present a rapidly evolving frontier.

    Breast Cancer: Dominant vs. Lung Cancer: Emerging

    Breast cancer stands as the dominant therapeutic area within the US oncology drugs market, characterized by significant investment and substantial advances in treatments, including hormonal therapies, chemotherapy, and monoclonal antibodies. Its broad range of available therapies has made it a focal point for pharmaceutical companies, leading to a wealth of options for patients. The segment benefits from a well-established infrastructure for research and support within healthcare systems, with a strong emphasis on patient advocacy and education propelling further advancements. In contrast, lung cancer, marked as an emerging segment, is rapidly gaining attention due to escalating patient numbers and breakthroughs in targeted biologic medications. Innovative treatments focusing on genetic mutations and immune responses are driving its progress, positioning lung cancer as a critical area for future therapeutic advancements and market growth.

    By Route of Administration: Intravenous (Largest) vs. Oral (Fastest-Growing)

    In the US oncology drugs market, the route of administration plays a crucial role in treatment effectiveness and patient adherence. Intravenous delivery holds the largest market share, largely favored for its rapid onset of action and ability to manage drug interactions effectively. Meanwhile, the oral route is gaining traction due to its convenience and ease of administration, especially for outpatient care, making it a significant player in the market. The growth trends in this segment indicate a notable shift towards oral formulations, driven by ongoing research and development aimed at improving bioavailability and patient compliance. Advances in drug delivery systems and the increasing preference for patient-centric treatment options are propelling the oral route to become the fastest-growing segment. Enhanced absorption and targeted therapeutic effects further underscore the potential of oral administration in the oncology drugs market.

    Intravenous (Dominant) vs. Oral (Emerging)

    Intravenous administration of oncology drugs is the dominant route due to its effectiveness in delivering high doses of anticancer therapies directly into the bloodstream, ensuring rapid therapeutic effects. This method is particularly valuable in acute treatment scenarios, such as chemotherapy, where immediate and potent action is required. Additionally, intravenous delivery minimizes issues related to gastrointestinal absorption, offering enhanced predictability in drug pharmacokinetics. On the other hand, oral administration is emerging as a preferred choice for long-term management due to its convenience and reduced hospital visits for patients. This route allows for self-administration, promoting higher adherence to treatment regimens. Continuous innovations in formulation technologies signal a burgeoning future for oral oncology drugs, as they aim to decrease side effects while maintaining efficacy.

    By Patient Demographics: Adult (Largest) vs. Pediatric (Fastest-Growing)

    The patient demographics segment in the US oncology drugs market is characterized by three main categories: Adult, Pediatric, and Geriatric. The Adult segment holds the largest market share, driven by the higher incidence rates of various cancers within this population. In contrast, the Pediatric segment is gaining traction, attributed to increasing awareness of childhood cancers and advancements in treatment options tailored for younger patients. Growth in the Pediatric segment is being propelled by ongoing research and development efforts focused on effective therapies specifically designed for children. Additionally, supportive regulations and funding for pediatric oncology programs are enhancing treatment accessibility and fostering innovation in this demographic. The Geriatric segment also presents opportunities, influenced by the aging population and the rising prevalence of cancer among older adults.

    Adult (Dominant) vs. Pediatric (Emerging)

    The Adult segment remains the dominant force in the US oncology drugs market due to a significant population base affected by various forms of cancer. With established treatment protocols and a broad range of available therapies, this demographic accounts for the majority of drug prescriptions. Conversely, the Pediatric segment is emerging as a critical area of focus, driven by an increase in investment for research and specialized treatments that address the unique oncological needs of children. The expansion of clinical trials for pediatric cancers and the push for more personalized treatment options are enhancing its market presence, indicating a shift in resources and attention towards younger patients.

    Get more detailed insights about US Oncology Drugs Market

    Key Players and Competitive Insights

    The oncology drugs market is characterized by intense competition and rapid innovation, driven by a growing demand for effective cancer therapies. Key players such as Roche (CH), Bristol Myers Squibb (US), and Merck & Co (US) are at the forefront, each adopting distinct strategies to enhance their market positions. Roche (CH) focuses on personalized medicine, leveraging its robust pipeline of targeted therapies, while Bristol Myers Squibb (US) emphasizes immuno-oncology, aiming to expand its portfolio through strategic acquisitions and partnerships. Merck & Co (US) is heavily investing in research and development, particularly in combination therapies, which positions it well to address diverse patient needs and improve treatment outcomes.

    The business tactics employed by these companies include localizing manufacturing and optimizing supply chains to enhance efficiency and reduce costs. The oncology drugs market appears moderately fragmented, with a mix of established players and emerging biotech firms. The collective influence of these key players shapes the competitive landscape, as they vie for market share through innovation and strategic collaborations.

    In October 2025, Roche (CH) announced a partnership with a leading biotech firm to co-develop a novel CAR-T cell therapy aimed at treating hematological malignancies. This collaboration is expected to accelerate the development timeline and enhance Roche's capabilities in the CAR-T space, reflecting its commitment to advancing personalized treatment options. The strategic importance of this partnership lies in its potential to strengthen Roche's position in a rapidly evolving segment of the oncology market.

    In September 2025, Bristol Myers Squibb (US) completed the acquisition of a promising biotech company specializing in next-generation immunotherapies. This acquisition is likely to bolster Bristol Myers Squibb's pipeline and enhance its competitive edge in immuno-oncology, a field that continues to attract significant investment and interest. The move underscores the company's strategy to expand its therapeutic offerings and maintain leadership in innovative cancer treatments.

    In August 2025, Merck & Co (US) launched a new combination therapy for lung cancer, which has shown promising results in clinical trials. This launch not only reinforces Merck's commitment to addressing unmet medical needs but also positions the company to capture a larger share of the lung cancer treatment market. The strategic importance of this launch is evident in its potential to improve patient outcomes and solidify Merck's reputation as a leader in oncology.

    As of November 2025, current trends in the oncology drugs market include a strong emphasis on digitalization, sustainability, and the integration of artificial intelligence in drug development. Strategic alliances are increasingly shaping the competitive landscape, enabling companies to pool resources and expertise. Looking ahead, competitive differentiation is likely to evolve, with a shift from price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This transition may redefine how companies approach market entry and product development, ultimately benefiting patients through improved therapeutic options.

    Key Companies in the US Oncology Drugs Market market include

    Industry Developments

    May 2023:AbbVie Inc. announced the U.S. FDA approval for its EPKINLY, among the only drugs for treating patients with relapsed or refractory diffuse large b-cell lymphoma (DLBCL).

    March 2023:Pfizer Inc. announced a merger agreement to acquire Seagen, Inc., a global biotechnology company manufacturing cancer medicines. The acquisition would strengthen Pfizer's capabilities and expertise inoncology.

    In December 2023, Absci Corporation, a pioneer in the production of generative artificial intelligence antibodies, entered into a partnership with AstraZeneca to use Absci's Drug CreationTM platform to supply AI-designed antibodies to other pharmaceutical companies. By using AstraZeneca's experience in oncology and Absci's de novo artificial intelligence antibody production platform, the objective is to develop a novel antibody therapeutic for the treatment of cancer.

    In February 2024, ImmunoGen, a biotechnology firm that focuses on the development of antibody-drug conjugate therapies for the treatment of cancer, was purchased by AbbVie Inc. to boost the business's position in the oncology market.

    In March of 2024, Fusion Pharmaceuticals Inc. is a clinical-stage biopharmaceutical business that focuses on developing next-generation radioconjugates (RCs). AstraZeneca agreed to a final agreement to purchase Fusion Pharmaceuticals Inc. This purchase represents a major development in AstraZeneca's attempts to reinvent cancer care by replacing conventional medicines, such as chemotherapy and radiation, with more tailored treatments that seek to improve patient outcomes. These treatments are intended to alleviate the suffering of cancer patients

    Future Outlook

    US Oncology Drugs Market Future Outlook

    The oncology drugs market is projected to grow at a 14.2% CAGR from 2024 to 2035, driven by advancements in targeted therapies, increasing cancer prevalence, and enhanced R&D investments.

    New opportunities lie in:

    • Development of personalized medicine platforms for tailored oncology treatments.
    • Expansion of telehealth services for remote patient monitoring and consultations.
    • Investment in AI-driven drug discovery to accelerate the development of novel therapies.

    By 2035, the oncology drugs market is expected to achieve substantial growth, reflecting evolving treatment paradigms and technological advancements.

    Market Segmentation

    US Oncology Drugs Market Type Outlook

    • Chemotherapy Drugs
    • Targeted Therapy Drugs
    • Immunotherapy Drugs
    • Hormonal Therapy Drugs

    US Oncology Drugs Market Therapeutic Area Outlook

    • Breast Cancer
    • Lung Cancer
    • Colorectal Cancer
    • Prostate Cancer
    • Leukemia

    US Oncology Drugs Market Patient Demographics Outlook

    • Adult
    • Pediatric
    • Geriatric

    US Oncology Drugs Market Route of Administration Outlook

    • Oral
    • Intravenous
    • Subcutaneous
    • Intramuscular

    Report Scope

    MARKET SIZE 202440.29(USD Billion)
    MARKET SIZE 202546.01(USD Billion)
    MARKET SIZE 2035173.63(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)14.2% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies Profiled["Roche (CH)", "Bristol Myers Squibb (US)", "Merck & Co (US)", "Novartis (CH)", "Pfizer (US)", "AstraZeneca (GB)", "Johnson & Johnson (US)", "Amgen (US)", "Gilead Sciences (US)"]
    Segments CoveredType, Therapeutic Area, Route of Administration, Patient Demographics
    Key Market OpportunitiesAdvancements in personalized medicine and immunotherapy are reshaping the oncology drugs market landscape.
    Key Market DynamicsRising demand for personalized medicine drives innovation and competition in the oncology drugs market.
    Countries CoveredUS

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    How much is the U.S. Oncology Drugs market?

    The U.S. Oncology Drugs market size was valued at USD 98.8 Billion in 2022.

    What is the growth rate of the U.S. Oncology Drugs market?

    The market is projected to grow at a CAGR of 15.50% during the forecast period, 2023-2032.

    Who are the key players in the U.S. Oncology Drugs market?

    The key players in the market areGlaxoSmithKline PIc.,Novartis AG,Merck & Co. Inc.,Eli Lilly and Company,Amgen Inc.,Bayer, Celgene Corporation,Johnson & Johnson, and Pfizer Inc.

    Which Typeled the U.S. Oncology Drugs market?

    The Targeted Therapy category dominated the market in 2022.

    Which Applicationhad the largest market share in the U.S. Oncology Drugs market?

    Breast Cancer had the largest share in the market.

    What is the expected market size of the US Oncology Drugs Market in 2024?

    The US Oncology Drugs Market is expected to be valued at 38.5 USD Billion in 2024.

    What will be the projected market size in 2035?

    By 2035, the US Oncology Drugs Market is anticipated to reach a valuation of 162.75 USD Billion.

    What is the expected CAGR for the US Oncology Drugs Market from 2025 to 2035?

    The expected CAGR for the US Oncology Drugs Market from 2025 to 2035 is 14.003%.

    Which drug classes are included in the US Oncology Drugs Market?

    The market is divided into Cytotoxic Drugs, Targeted Drugs, Hormonal Drugs, and Others.

    What is the market value for Cytotoxic Drugs in 2024?

    In 2024, the market value for Cytotoxic Drugs is estimated at 9.5 USD Billion.

    What will be the market size of Targeted Drugs by 2035?

    The market size for Targeted Drugs is projected to be 66.5 USD Billion by 2035.

    What is the estimated value of Hormonal Drugs in the market for 2024?

    For the year 2024, the estimated value of Hormonal Drugs is 8.5 USD Billion.

    Who are the key players in the US Oncology Drugs Market?

    Major players include Bristol Myers Squibb, Novartis, AstraZeneca, Merck, and Eli Lilly.

    How is the market expected to grow for Other Drugs from 2024 to 2035?

    The market for Other Drugs is expected to grow from 5.0 USD Billion in 2024 to 20.5 USD Billion in 2035.

    What growth opportunities exist in the US Oncology Drugs Market?

    The market presents growth opportunities through innovation in drug development and increasing prevalence of cancer.

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