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    US Biologics Market

    ID: MRFR/HC/18045-HCR
    100 Pages
    Rahul Gotadki
    September 2025

    US Biologics Market Research Report By Product Service (Monoclonal Antibody, Interleukins, Vaccines, Growth Factors, Gene Therapy, Others) and By Disease Indication (Rheumatoid Arthritis, Psoriasis/Psoriatic Arthritis, Cancer, Diabetes, Others)- Forecast to 2035

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    US Biologics Market Research Report — Global Forecast till 2035 Infographic
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    Table of Contents

    US Biologics Market Summary

    The US Biologics market is projected to grow from 129.4 USD Billion in 2024 to 350 USD Billion by 2035, indicating robust expansion.

    Key Market Trends & Highlights

    US Biologics Key Trends and Highlights

    • The US Biologics market is valued at 129.4 USD Billion in 2024.
    • By 2035, the market is expected to reach 350 USD Billion, showcasing substantial growth.
    • The compound annual growth rate (CAGR) for the period from 2025 to 2035 is estimated at 9.47 percent.
    • Growing adoption of biologics due to increasing prevalence of chronic diseases is a major market driver.

    Market Size & Forecast

    2024 Market Size 129.4 (USD Billion)
    2035 Market Size 350 (USD Billion)
    CAGR (2025-2035) 9.47%

    Major Players

    AbbVie, Johnson and Johnson, Genentech, Biogen, Bristol-Myers Squibb, Amgen, Eli Lilly and Company, Merck and Co, Gilead Sciences, Pfizer, Sanofi, Novartis, Vertex Pharmaceuticals, AstraZeneca, Regeneron Pharmaceuticals

    US Biologics Market Trends

    The US Biologics Market has Substantial activity owing to the shifts in biotechnology and the increased spending on research and development activities. An important factor that is propelling the market is the increasing incidence of chronic diseases that require effective treatments. Furthermore, the demand for biologics is being driven by the aging population because the elderly need treatment for cancer, autoimmune diseases, diabetes, and many other diseases. It is easy to find prospects in the US Biologics Market, especially now, with the increasing adoption of personalized medicine.

    The American population is becoming far more commonplace to treat with tactics that aim to boost processes to increase efficiency and effectiveness while minimizing the side effects. The adoption of artificial intelligence and machine learning technology in the drug discovery cycle offers another growth opportunity by allowing companies to reduce spending on research and efficiently commercialize new products. In addition, biosimilars are projected to have a significant impact as they can broaden the market to essential therapies and biologics, thus enabling the public to have access to these more affordable alternatives.

    There is a noticeable shift toward more supportive trends for the biologics which had neglected the supports; for example, the FDA started to enact measures for accelerating the introduction of new treatments to the market.

    The US Pharma industry is internally collaborative in order to balance patient safety and foster innovations. This, along with increased cooperation between pharmaceutical companies and academic institutions, will increase the efficiency of biologics development over the years. Continuous progress in these areas indicates a vibrant upcoming landscape within the biologics market driven by enhanced commitment toward patient care and fresh opportunities to innovate.

    US Biologics Market Drivers

    Market Segment Insights

    Biologics Market Product Service Insights  

    The US Biologics Market is experiencing significant growth, especially within the Product Service segment, driven by an increasing demand for advanced therapeutics and precision medicine. This segment encompasses various areas such as Monoclonal Antibodies, Interleukins, Vaccines, Growth Factors, Gene Therapy, and others. Monoclonal Antibodies have gained immense popularity due to their efficacy in targeting specific pathogens and diseases, making them essential tools in the treatment of conditions like cancer and autoimmune disorders. Their capacity to provide personalized medicine is positioning these therapeutic agents at the forefront of medical innovation.

    Similarly, Interleukins play a crucial role in enhancing immune responses, facilitating advances in treating chronic inflammatory diseases, and providing new avenues for cancer immunotherapy. Vaccines remain prominent, particularly given the recent global health challenges, with a renewed focus on ensuring widespread access and the development of next-generation vaccines that offer enhanced efficacy and safety profiles. Growth Factors are vital in regenerative medicine, driving advancements in cellular therapies and tissue engineering. Their importance is underscored by their potential in treating degenerative diseases and injuries.

    Gene Therapy is expanding rapidly, allowing for innovative approaches to correct genetic disorders at their root cause, making profound societal impacts by potentially eradicating hereditary diseases. Collectively, these areas represent significant opportunities for growth in the US Biologics Market. Each of these segments contributes to an evolving landscape of biopharmaceuticals, addressing complex health challenges faced by the population and reflecting the shift towards more targeted and personalized treatment options. The US continues to be a hub for innovation in these fields, bolstered by robust R initiatives conducted by leading biopharmaceutical companies and supported by favorable regulatory environments.

    As a result, the importance of the Product Service segment within the overall US Biologics Market cannot be overstated, as it continuously adapts and responds to the changing needs of patients and healthcare systems across the nation.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Biologics Market Disease Indication Insights  

    The Disease Indication segment of the US Biologics Market showcases significant diversity and demand across various therapeutic areas. Notably, Rheumatoid Arthritis and Psoriasis/Psoriatic Arthritis represent critical areas, given their prevalence and the chronic nature of these diseases, significantly impacting patient quality of life. Cancer therapies also play a pivotal role in driving advances within the market, reflecting the increasing investment in innovative biologics to target specific malignancies and improve survival rates. Furthermore, as the incidence of diabetes continues to rise, related biologics are crucial for management and treatment, addressing the pressing health challenge faced by the US population.

    Market trends also reveal a shift toward personalized medicine, fostering growth driven by the development of novel therapies tailored to individual patient profiles. Simultaneously, challenges include regulatory complexities and high R costs that impact market entry. Overall, the US Biologics Market segmentation in Disease Indication reflects a robust landscape poised for continued evolution and growth, addressing critical healthcare challenges with innovative solutions.

    Get more detailed insights about US Biologics Market Research Report — Global Forecast till 2035

    Regional Insights

    Key Players and Competitive Insights

    The US Biologics Market is a highly dynamic and competitive landscape characterized by rapid advancements in biotechnology and a surge in demand for innovative therapeutics. The biologics sector encompasses a wide range of products, including monoclonal antibodies, vaccines, and therapeutic proteins, all of which address various medical conditions. 

    The market is shaped by factors such as the growing prevalence of chronic diseases, expanding healthcare expenditure, and an increasing focus on personalized medicine. As a result, companies operating in this space must continuously innovate while navigating a complex regulatory environment, intense competition from both established firms and emerging biotech companies, as well as ongoing pricing pressures from payers and healthcare providers. AbbVie holds a prominent position in the US Biologics Market, exhibiting strong capabilities in the development and commercialization of biologics.

    The company is recognized for its robust portfolio of immunology and oncology products, which have been instrumental in addressing patient needs across various therapeutic areas. AbbVie's investment in research and development has led to breakthrough treatments that enhance patient outcomes and solidify its reputation as a leader in the biotech field. Additionally, AbbVie benefits from successful collaborations, partnerships, and a commitment to advancing science, which further strengthens its foothold in the US market. The company relies on its expertise and resources to maintain competitive advantages, ensuring sustained growth and market presence.

    Johnson and Johnson has established itself as a significant player in the US Biologics Market, with a diverse range of key products and services that cater to several therapeutic areas, including immunology, oncology, and infectious diseases. The company’s commitment to innovation is evident through its continuous investments in research and development aimed at delivering transformative therapies to patients. Johnson and Johnson's strengths lie in its extensive market presence, 

    global reach, and value-driven approach, which leverage synergies between its pharmaceutical and consumer divisions. The company's history of successful mergers and acquisitions has further bolstered its biologics portfolio and allowed it to capitalize on emerging market trends. By strategically positioning itself within the US market, Johnson and Johnson remains resilient against competitive pressures, showcasing its capability to adapt and excel in the ever-evolving landscape of biologics.

    Key Companies in the US Biologics Market market include

    Industry Developments

    The US Biologics Market has seen significant developments recently, particularly with prominent companies like AbbVie, Johnson  Johnson, Genentech, and Bristol-Myers Squibb leading the way. In September 2023, Regeneron Pharmaceuticals announced a strategic collaboration with AstraZeneca aimed at advancing oncology treatments, which is set to enhance both companies' portfolios in biologics. Moreover, Biogen and Eli Lilly showcased promising data regarding their respective Alzheimer's therapies, highlighting the ongoing focus on neurological conditions. The market valuation for biologics in the US continues to grow, driven by increased investment and innovation.

    Products that target chronic diseases and personalized medicine are expanding rapidly, with Gilead Sciences making strides in HIV treatment advancements. Notably, the acquisition trend remains active, with Amgen acquiring Five Prime Therapeutics in April 2021 to bolster its oncology pipeline, enhancing its market position. Over the past two years, the US biologics sector has witnessed substantial investment, resulting in a robust pipeline of new therapies, reflecting a noteworthy shift towards biologics as primary treatment modalities in various disease categories.

    Market Segmentation

    Biologics Market Product Service Outlook

    • Monoclonal Antibody
    • Interleukins
    • Vaccines
    • Growth Factors
    • Gene Therapy
    • Others

    Biologics Market Disease Indication Outlook

    • Rheumatoid Arthritis
    • Psoriasis/Psoriatic Arthritis
    • Cancer
    • Diabetes
    • Others

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 111.33(USD Billion)
    Market Size 2024 129.41(USD Billion)
    Market Size 2035 350.0(USD Billion)
    Compound Annual Growth Rate (CAGR) 9.466% (2025 - 2035)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled AbbVie, Johnson  and  Johnson, Genentech, Biogen, Bristol-Myers Squibb, Amgen, Eli Lilly and Company, Merck  and  Co, Gilead Sciences, Pfizer, Sanofi, Novartis, Vertex Pharmaceuticals, AstraZeneca, Regeneron Pharmaceuticals
    Segments Covered Product Service, Disease Indication
    Key Market Opportunities Personalized medicine advancements, Biosimilars market growth, Expanding gene therapy applications, Immunotherapy innovation and demand, Increased R investment in biologics
    Key Market Dynamics Aging population, Increasing chronic diseases, Advancements in biotechnology, Rising healthcare expenditure, Favorable regulatory environment
    Countries Covered US

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the expected market size of the US Biologics Market in 2024?

    The US Biologics Market is expected to be valued at approximately 129.41 USD Billion in 2024.

    What will the market size of the US Biologics Market be by 2035?

    By 2035, the US Biologics Market is projected to reach around 350.0 USD Billion.

    What is the expected compound annual growth rate (CAGR) of the US Biologics Market from 2025 to 2035?

    The expected CAGR for the US Biologics Market from 2025 to 2035 is 9.466%.

    Which product segment is expected to dominate the US Biologics Market in 2024?

    In 2024, the Monoclonal Antibody segment is expected to dominate the market, valued at 50.0 USD Billion.

    How much is the Interleukins segment forecasted to be valued in 2035?

    The Interleukins segment is projected to be valued at around 55.0 USD Billion by 2035.

    Who are the key players in the US Biologics Market?

    Major players in the US Biologics Market include AbbVie, Johnson and Johnson, Genentech, Biogen, and Bristol-Myers Squibb among others.

    What is the expected market value for Vaccines in 2024?

    The Vaccines segment is expected to be valued at approximately 30.0 USD Billion in 2024.

    What are the growth prospects for the Gene Therapy segment by 2035?

    The Gene Therapy segment is anticipated to grow to a market value of around 45.0 USD Billion by 2035.

    What factors could potentially drive growth in the US Biologics Market?

    Factors driving growth include increasing demand for innovative therapies and advancements in biotechnology.

    What challenges could impact the US Biologics Market over the forecast period?

    Challenges may include regulatory hurdles and high costs associated with biologics development and production.

    What is the forecasted market size of the US Biologics Market in 2024?

    The US Biologics Market is expected to be valued at 135.0 USD Billion in 2024.

    What will the US Biologics Market be valued at by 2035?

    By 2035, the US Biologics Market is projected to reach 750.0 USD Billion.

    What is the expected compound annual growth rate (CAGR) for the US Biologics Market from 2025 to 2035?

    The expected CAGR for the US Biologics Market from 2025 to 2035 is 16.87%.

    Which product service segment is projected to dominate the US Biologics Market in 2035?

    The Monoclonal Antibody segment is expected to dominate with a valuation of 350.0 USD Billion in 2035.

    What is the market size for Interleukins in the US Biologics Market in 2024?

    The Interleukins segment is valued at 15.0 USD Billion in 2024.

    What is the key application driving growth in the US Biologics Market?

    Monoclonal Antibodies are a key application driving significant growth in the US Biologics Market.

    How much is the Vaccines segment projected to be worth by 2035?

    The Vaccines segment is projected to reach a value of 180.0 USD Billion by 2035.

    Who are the key competitors in the US Biologics Market?

    Major players include Merck and Co, Biogen, Novartis, and Gilead Sciences among others.

    What are the growth prospects for the Growth Factors segment by 2035?

    The Growth Factors segment is expected to reach a valuation of 70.0 USD Billion by 2035.

    What is the projected market value of Gene Therapy in 2035?

    Gene Therapy is anticipated to be valued at 60.0 USD Billion by 2035.

    1. 'TABLE OF CONTENTS
    2. EXECUTIVE SUMMARY
      1. Market Overview
      2. Key Findings
      3. Market Segmentation
      4. Competitive Landscape
      5. Challenges and Opportunities
      6. Future Outlook
    3. MARKET INTRODUCTION
      1. Definition
      2. Scope of the study
        1. Research Objective
        2. Assumption
        3. Limitations
    4. RESEARCH METHODOLOGY
      1. Overview
      2. Data Mining
    5. Secondary Research
      1. Primary Research
        1. Primary Interviews and
    6. Information Gathering Process
      1. Breakdown of Primary Respondents
      2. Forecasting Model
      3. Market Size Estimation
        1. Bottom-Up
    7. Approach
      1. Top-Down Approach
      2. Data Triangulation
    8. Validation
    9. MARKET DYNAMICS
      1. Overview
    10. Drivers
      1. Restraints
      2. Opportunities
    11. MARKET FACTOR ANALYSIS
      1. Value chain Analysis
      2. Porter''s Five Forces Analysis
    12. Bargaining Power of Suppliers
      1. Bargaining Power of Buyers
    13. Threat of New Entrants
      1. Threat of Substitutes
        1. Intensity
    14. of Rivalry
      1. COVID-19 Impact Analysis
        1. Market Impact Analysis
        2. Regional Impact
        3. Opportunity and Threat Analysis
    15. U.S. BIOLOGICS MARKET, BY PRODUCT SERVICE (USD BILLION)
    16. Monoclonal Antibody
      1. Interleukins
      2. Vaccines
      3. Growth
    17. Factors
      1. Gene Therapy
      2. Others
    18. U.S. BIOLOGICS MARKET,
    19. BY DISEASE INDICATION (USD BILLION)
      1. Rheumatoid Arthritis
      2. Psoriasis/Psoriatic
    20. Arthritis
      1. Cancer
      2. Diabetes
      3. Others
    21. COMPETITIVE LANDSCAPE
      1. Overview
      2. Competitive Analysis
      3. Market share Analysis
      4. Major Growth Strategy in the Biologics
    22. Market
      1. Competitive Benchmarking
      2. Leading Players in Terms of
    23. Number of Developments in the Biologics Market
      1. Key developments and growth
    24. strategies
      1. New Product Launch/Service Deployment
        1. Merger
    25. & Acquisitions
      1. Joint Ventures
      2. Major Players Financial
    26. Matrix
      1. Sales and Operating Income
        1. Major Players R&D
    27. Expenditure. 2023
    28. COMPANY PROFILES
      1. AbbVie
        1. Financial
    29. Overview
      1. Products Offered
        1. Key Developments
    30. SWOT Analysis
      1. Key Strategies
      2. Johnson and Johnson
    31. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. Genentech
    32. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. Biogen
    33. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. BristolMyers Squibb
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      3. Amgen
    34. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. Eli Lilly and Company
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      3. Merck and Co
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      4. Gilead Sciences
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      5. Pfizer
    35. Financial Overview
      1. Products Offered
        1. Key Developments
        2. SWOT Analysis
        3. Key Strategies
      2. Sanofi
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      3. Novartis
        1. Financial Overview
        2. Products Offered
        3. Key Developments
        4. SWOT Analysis
        5. Key Strategies
      4. Vertex Pharmaceuticals
        1. Financial Overview
        2. Products Offered
        3. Key
    36. Developments
      1. SWOT Analysis
        1. Key Strategies
    37. AstraZeneca
      1. Financial Overview
        1. Products Offered
        2. Key Developments
        3. SWOT Analysis
        4. Key Strategies
      2. Regeneron Pharmaceuticals
        1. Financial Overview
    38. Products Offered
      1. Key Developments
        1. SWOT Analysis
        2. Key Strategies
    39. APPENDIX
      1. References
      2. Related
    40. Reports
    41. U.S. BIOLOGICS MARKET SIZE ESTIMATES & FORECAST, BY PRODUCT SERVICE, 2019-2035
    42. (USD BILLIONS)
    43. BY DISEASE INDICATION, 2019-2035 (USD BILLIONS)
    44. DEVELOPMENT/APPROVAL
    45. ANALYSIS BY PRODUCT SERVICE
    46. INDICATION
    47. RESEARCH PROCESS OF MRFR
    48. IMPACT ANALYSIS: BIOLOGICS MARKET
    49. MARKET
    50. BIOLOGICS MARKET, BY DISEASE INDICATION, 2019 TO 2035 (USD Billions)
    51. BENCHMARKING OF MAJOR COMPETITORS'

    U.S. Biologics Market Segmentation

    • Biologics Market By Product Service (USD Billion, 2025-2035)
      • Monoclonal Antibody
      • Interleukins
      • Vaccines
      • Growth Factors
      • Gene Therapy
      • Others
    • Biologics Market By Disease Indication (USD Billion, 2025-2035)
      • Rheumatoid Arthritis
      • Psoriasis/Psoriatic Arthritis
      • Cancer
      • Diabetes
      • Others
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