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    UK hERG Screening Market

    ID: MRFR/HC/51275-HCR
    200 Pages
    Garvit Vyas
    October 2025

    UK hERG Screening Market Research Report By Type (Gene KCNH2, Mutant KCNH2), By Ion Channel (Voltage Gated, Ligand Gated) and By Application (Antiarrhythmic, Antipsychotic, Antibiotics, Others)- Forecast to 2035

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    UK hERG Screening Market Infographic
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    UK hERG Screening Market Summary

    As per MRFR analysis, the UK hERG screening market size was estimated at 50.4 USD Million in 2024. The UK herg screening market is projected to grow from 55.97 USD Million in 2025 to 159.8 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 11.06% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The UK Herg screening market is poised for growth driven by regulatory compliance and technological advancements.

    • Regulatory compliance and safety standards are increasingly shaping the UK Herg screening market.
    • Technological advancements in screening methods are enhancing the accuracy and efficiency of Herg testing.
    • The integration of automation and AI is streamlining processes, potentially reducing time and costs in drug development.
    • Rising demand for cardiotoxicity testing and increased investment in drug development are key drivers propelling market expansion.

    Market Size & Forecast

    2024 Market Size 50.4 (USD Million)
    2035 Market Size 159.8 (USD Million)

    Major Players

    Thermo Fisher Scientific (US), Charles River Laboratories (US), Eurofins Scientific (FR), Celerion (US), Crown Bioscience (US), Inotiv (US), Boehringer Ingelheim (DE), Scripps Research (US), AstraZeneca (GB)

    UK hERG Screening Market Trends

    the hERG screening market is currently experiencing notable growth, driven by increasing awareness of the importance of cardiac safety in drug development. Regulatory bodies emphasize the need for thorough testing of drug candidates to identify potential risks associated with hERG channel inhibition. This heightened focus on safety has led to a surge in demand for effective hERG screening solutions, as pharmaceutical companies seek to mitigate the risk of adverse cardiac events. Furthermore, advancements in technology are facilitating more efficient and accurate screening processes, which may enhance the overall drug development timeline. In addition, the hERG screening market is witnessing a shift towards the adoption of high-throughput screening methods. These innovative approaches allow for the simultaneous testing of multiple compounds, thereby expediting the identification of hERG liability. As the pharmaceutical industry continues to evolve, the integration of automation and artificial intelligence into screening processes appears to be a growing trend. This evolution not only improves the accuracy of results but also reduces the time and costs associated with traditional screening methods, making it a compelling option for companies aiming to streamline their drug development efforts.

    Regulatory Compliance and Safety Standards

    The herg screening market is increasingly influenced by stringent regulatory requirements. Authorities are mandating comprehensive cardiac safety assessments for new drug candidates, which drives the need for reliable screening solutions. Companies are adapting to these regulations by investing in advanced technologies that ensure compliance and enhance safety profiles.

    Technological Advancements in Screening Methods

    Recent innovations in technology are transforming the herg screening market. High-throughput screening techniques are becoming more prevalent, allowing for rapid assessment of multiple compounds. This shift not only accelerates the screening process but also improves the accuracy of results, which is crucial for effective drug development.

    Integration of Automation and AI

    The herg screening market is witnessing a growing trend towards automation and artificial intelligence. These technologies are being integrated into screening processes to enhance efficiency and precision. By reducing human error and streamlining workflows, automation and AI are likely to play a pivotal role in the future of hERG screening.

    UK hERG Screening Market Drivers

    Growing Focus on Personalized Medicine

    the hERG screening market is being influenced by the rising emphasis on personalized medicine., which aims to tailor treatments to individual patient profiles. This shift necessitates a deeper understanding of drug interactions and potential side effects, particularly concerning cardiac health. As healthcare providers in the UK increasingly adopt personalized approaches, the demand for comprehensive herg screening is likely to rise. The market is projected to grow by approximately 10% annually as pharmaceutical companies seek to develop targeted therapies with minimized cardiac risks. This trend underscores the importance of herg screening in ensuring that personalized medicine strategies are both effective and safe for patients, thereby enhancing the overall value of the herg screening market.

    Increased Investment in Drug Development

    Investment in drug development is a critical driver for the herg screening market, particularly in the UK, where pharmaceutical companies are allocating substantial resources to research and development. The UK government has been supportive of innovation in the life sciences sector, providing funding and incentives for companies to enhance their drug discovery processes. As a result, the herg screening market is likely to benefit from increased funding, which is expected to exceed £1 billion in 2025. This influx of capital may facilitate the adoption of advanced screening technologies and methodologies, thereby improving the efficiency and accuracy of herg screening processes. Consequently, the herg screening market is poised for growth as companies strive to bring safer drugs to market.

    Rising Demand for Cardiotoxicity Testing

    The herg screening market is experiencing a notable increase in demand for cardiotoxicity testing, driven by the growing awareness of drug-induced cardiac risks. Regulatory bodies in the UK are emphasizing the importance of assessing the safety profiles of new pharmaceuticals, particularly those targeting the cardiovascular system. This heightened focus on patient safety is likely to propel the market forward, as pharmaceutical companies seek to comply with stringent regulations. In 2025, the market for cardiotoxicity testing is projected to reach approximately £300 million, reflecting a compound annual growth rate (CAGR) of around 8%. This trend indicates a robust growth trajectory for the herg screening market, as stakeholders prioritize the identification of potential cardiac liabilities in drug development.

    Regulatory Pressure for Comprehensive Testing

    Regulatory pressure for comprehensive testing is a significant driver for the herg screening market in the UK. Authorities are increasingly mandating thorough evaluations of drug candidates to ensure their safety profiles, particularly concerning cardiac effects. This regulatory landscape compels pharmaceutical companies to invest in robust herg screening processes to meet compliance requirements. As a result, the hERG screening market is expected to grow by approximately 6% annually, as companies strive to align with evolving regulations. The emphasis on comprehensive testing not only enhances patient safety but also fosters a culture of accountability within the pharmaceutical industry, thereby reinforcing the importance of herg screening in the drug development pipeline.

    Emergence of Innovative Screening Technologies

    the hERG screening market is witnessing a transformation due to the emergence of innovative screening technologies. Advancements in high-throughput screening and in silico modeling are enabling more efficient and accurate assessments of drug candidates. In the UK, research institutions and biotech companies are collaborating to develop cutting-edge tools that enhance the predictive capabilities of herg screening. These innovations are expected to reduce the time and costs associated with drug development, potentially saving the industry millions of pounds. As these technologies gain traction, the herg screening market is likely to expand, with an anticipated growth rate of 7% over the next five years. This evolution reflects the ongoing commitment to improving drug safety and efficacy through enhanced screening methodologies.

    Market Segment Insights

    hERG

    The UK hERG Screening Market has been categorized based on Type, with a distinct focus on Gene KCNH2 and Mutant KCNH2, which play pivotal roles in cardiac research and pharmacological testing. Gene KCNH2 is known for its significant contribution to potassium ion channel activities and cardiac repolarization processes, making it critical for understanding arrhythmias and developing targeted therapies. As healthcare providers and pharmaceutical companies in the UK increasingly prioritize personalized medicine, the relevance of Gene KCNH2 in tailoring treatments for specific patient profiles continues to grow.

    This segment has garnered attention due to its impact on drug safety and efficacy, allowing for more accurate predictions of patient responses to medications. On the other hand, Mutant KCNH2 is equally significant, highlighting the genetic variations affecting potassium channels' functionality. The exploration of these mutations is essential for recognizing how certain populations might be predisposed to health risks, particularly in relation to inherited long QT syndrome. The importance of this type of segment lies in its application for developing genetic screening programs and ensuring compliance with regulatory standards aimed at minimizing adverse drug reactions.

    HERG

    The Ion Channel segment of the UK hERG Screening Market plays a crucial role in the broader landscape of drug development and safety assessments. This market is characterized by its focus on understanding the complex mechanisms that regulate ionic currents across cell membranes, which is critical in evaluating the cardiac safety profiles of new pharmaceuticals.

    Among the various types of ion channels, voltage-gated channels and ligand-gated channels hold significant importance due to their roles in action potentials and neurotransmission, respectively.Voltage-gated channels are essential for action potential propagation in cardiac and neuronal tissues, making them a focal point in screening for arrhythmogenic potentials in drug candidates. Conversely, ligand-gated channels facilitate rapid signaling in response to neurotransmitters, making them vital in assessing the safety and efficacy of neuropharmaceuticals.

    HERG

    The UK hERG Screening Market is largely informed by various applications, which play a crucial role in assessing the safety and effectiveness of pharmaceutical compounds. Among these, the Antiarrhythmic application is significant as it addresses heart rhythm disorders, making advancements inhERG Screening imperative to prevent QT interval prolongation and related complications. The Antipsychotic application is also pivotal, as mental health medications require rigorous screening to ensure patient safety and minimize adverse effects.

    The Antibiotics segment reflects an increasing demand for effective treatments, underscoring the necessity of thoroughhERG Screening processes to prevent cardiac toxicity in patients.Additionally, other applications contribute to market diversity, as they address varying therapeutic needs across the healthcare spectrum. This segmentation highlights the UK's commitment to maintaining high safety standards in drug development, thereby enhancing patient care and driving notable advancements in the UK hERG Screening Market industry. The trends indicate that heightened regulatory scrutiny is pushing for more innovative solutions, fundamentally shaping the market landscape.

    UK

    Robust UK hERG Screening Market data suggests that understanding these applications can provide strategic insights into future growth opportunities while addressing current healthcare challenges.

    Get more detailed insights about UK hERG Screening Market

    Key Players and Competitive Insights

    The herg screening market is characterized by a dynamic competitive landscape, driven by increasing regulatory scrutiny and the growing demand for safer pharmaceuticals. Key players are actively engaging in strategies that emphasize innovation, partnerships, and regional expansion to enhance their market positions. For instance, Thermo Fisher Scientific (US) has focused on integrating advanced technologies into its screening processes, thereby improving efficiency and accuracy. Similarly, Charles River Laboratories (US) has been expanding its service offerings through strategic acquisitions, which allows it to provide comprehensive solutions to its clients. These strategies collectively contribute to a competitive environment that is increasingly focused on technological advancement and service diversification.

    In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market appears moderately fragmented, with several key players exerting influence over specific segments. This fragmentation allows for niche players to thrive, while larger companies leverage their scale to dominate the market. The collective influence of these key players shapes the market structure, fostering an environment where innovation and service quality are paramount.

    In October 2025, Eurofins Scientific (FR) announced the launch of a new high-throughput herg screening platform designed to accelerate drug development timelines. This strategic move is significant as it positions Eurofins to capture a larger share of the market by addressing the urgent need for faster testing solutions. The introduction of this platform is likely to enhance their competitive edge, particularly among pharmaceutical companies seeking to streamline their research and development processes.

    In September 2025, AstraZeneca (GB) entered into a partnership with Scripps Research (US) to develop novel herg screening methodologies. This collaboration is indicative of a broader trend towards strategic alliances that combine expertise from different sectors. By leveraging Scripps' research capabilities, AstraZeneca aims to enhance its drug safety assessments, which could lead to more effective and safer therapeutic options in the market.

    In August 2025, Boehringer Ingelheim (DE) announced an investment in AI-driven technologies for herg screening, aiming to improve predictive accuracy in drug safety evaluations. This investment reflects a growing trend towards the integration of artificial intelligence in the pharmaceutical industry, which may revolutionize how drug safety is assessed. The strategic importance of this move lies in its potential to reduce the time and costs associated with traditional screening methods, thereby enhancing Boehringer's competitive positioning.

    As of November 2025, the herg screening market is witnessing trends that emphasize digitalization, sustainability, and the integration of AI technologies. Strategic alliances are increasingly shaping the competitive landscape, allowing companies to pool resources and expertise. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition to a focus on innovation, technological advancements, and supply chain reliability. This shift suggests that companies that prioritize these areas will be better positioned to thrive in an increasingly complex market.

    Key Companies in the UK hERG Screening Market market include

    Industry Developments

    Recent developments in the UK hERG Screening Market have highlighted significant advancements and collaborations among key players. Companies like PerkinElmer and Roche have been focusing on enhancing their screening technologies, with new contracts and partnerships expected to drive growth. In September 2023, Bristol-Myers Squibb expanded its portfolio by investing in HERG channel profiling technologies, indicating a strong market interest in drug safety and efficacy assessments. As of July 2023, Pfizer announced a strategic collaboration with Illumina to leverage genomic data for more efficienthERG Screening processes.

    Mergers and acquisitions have also shaped the landscape; Merck KGaA completed its acquisition of a biotechnology firm specializing inhERG Screening technologies in October 2022, strengthening its position in the market. The UK government emphasizes the importance of such technologies in drug discovery, leading to increased funding for innovative research in this area. The growth in valuation for companies like AstraZeneca and Thermo Fisher Scientific further demonstrates a robust and competitive market environment. Over the past few years, the focus on regulatory compliance in drug development has intensified, with industry leaders striving to meet the evolving demands for safety assessments.

    UK hERG Screening Market Segmentation Insights

    hERGScreening Market Type Outlook

    • Gene KCNH2
    • Mutant KCNH2

    hERGScreening Market Ion Channel Outlook

    • Voltage Gated
    • Ligand Gated

    hERGScreening Market Application Outlook

    • Antiarrhythmic
    • Antipsychotic
    • Antibiotics
    • Others

     

    Future Outlook

    UK hERG Screening Market Future Outlook

    The herg screening market is projected to grow at 11.06% CAGR from 2024 to 2035, driven by technological advancements, regulatory demands, and increasing drug development activities.

    New opportunities lie in:

    • Development of AI-driven predictive analytics tools for herg screening.
    • Expansion of high-throughput screening technologies in laboratories.
    • Partnerships with biotech firms for integrated herg testing solutions.

    By 2035, the herg screening market is expected to achieve substantial growth and innovation.

    Market Segmentation

    UK hERG Screening Market Type Outlook

    • Gene KCNH2
    • Mutant KCNH2

    UK hERG Screening Market Application Outlook

    • Antiarrhythmic
    • Antipsychotic
    • Antibiotics
    • Others

    UK hERG Screening Market Ion Channel Outlook

    • Voltage Gated
    • Ligand Gated

    Report Scope

    MARKET SIZE 2024 50.4(USD Million)
    MARKET SIZE 2025 55.97(USD Million)
    MARKET SIZE 2035 159.8(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 11.06% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Thermo Fisher Scientific (US), Charles River Laboratories (US), Eurofins Scientific (FR), Celerion (US), Crown Bioscience (US), Inotiv (US), Boehringer Ingelheim (DE), Scripps Research (US), AstraZeneca (GB)
    Segments Covered Type, Ion Channel, Application
    Key Market Opportunities Advancements in automated herg screening technologies enhance drug safety and regulatory compliance in the UK.
    Key Market Dynamics Regulatory changes drive innovation in Herg screening technologies, enhancing drug safety assessments in the UK.
    Countries Covered UK

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    FAQs

    What is the projected market size of the UK HERG Screening Market in 2024?

    The UK HERG Screening Market is expected to be valued at 70.56 million USD in 2024.

    What is the estimated market value for the UK HERG Screening Market by the year 2035?

    By 2035, the UK HERG Screening Market is expected to reach a value of 195.96 million USD.

    What is the expected CAGR for the UK HERG Screening Market from 2025 to 2035?

    The expected compound annual growth rate for the UK HERG Screening Market from 2025 to 2035 is 9.731%.

    Which segment of the UK HERG Screening Market is projected to have the highest value in 2035?

    The Mutant KCNH2 segment is projected to have a market value of 110.96 million USD in 2035.

    What market size is anticipated for the Gene KCNH2 segment in 2024?

    The Gene KCNH2 segment is anticipated to be valued at 30.0 million USD in 2024.

    Who are some of the major players in the UK HERG Screening Market?

    Key players in the market include PerkinElmer, Siemens Healthineers, and BristolMyers Squibb among others.

    What opportunities are driving growth in the UK HERG Screening Market?

    Emerging technologies and increasing awareness of genetic testing are significant growth drivers.

    How does the UK HERG Screening Market size compare between segments in 2024?

    In 2024, the Mutant KCNH2 segment is valued at 40.56 million USD, outperforming Gene KCNH2.

    What challenges might affect the growth of the UK HERG Screening Market?

    Regulatory hurdles and market competition are notable challenges affecting the market's growth.

    What is the projected market growth rate specifically for the Mutant KCNH2 segment from 2025 to 2035?

    The Mutant KCNH2 segment is expected to grow significantly within the overall market growth rate of 9.731%.

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