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    South Korea hERG Screening Market

    ID: MRFR/HC/51276-HCR
    200 Pages
    Garvit Vyas
    October 2025

    South Koreah ERG screening Market Research Report By Type (Gene KCNH2, Mutant KCNH2), By Ion Channel (Voltage Gated, Ligand Gated), and By Application (Antiarrhythmic, Antipsychotic, Antibiotics, Others)- Forecast to 2035

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    South Korea hERG Screening Market Infographic
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    South Korea hERG Screening Market Summary

    As per MRFR analysis, the herg screening market Size was estimated at 28.0 USD Million in 2024. The herg screening market is projected to grow from 31.09 USD Million in 2025 to 88.6 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 11.04% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The South Korea HERG screening market is poised for growth driven by regulatory demands and technological advancements.

    • Regulatory compliance and safety standards are increasingly shaping the HERG screening landscape in South Korea.
    • Technological advancements in screening methods are enhancing the accuracy and efficiency of HERG testing.
    • Collaborative research initiatives are fostering innovation and knowledge sharing within the HERG screening sector.
    • Rising demand for cardiac safety testing and increased investment in drug development are key drivers propelling market growth.

    Market Size & Forecast

    2024 Market Size 28.0 (USD Million)
    2035 Market Size 88.6 (USD Million)

    Major Players

    Thermo Fisher Scientific (US), Charles River Laboratories (US), Eurofins Scientific (LU), Celerion (US) - remove duplicate - remove duplicate - remove duplicate, CROMSOURCE (IT), Celerion (US), Inotiv (US), Celerion (US)

    South Korea hERG Screening Market Trends

    The herg screening market in South Korea is currently experiencing notable growth, driven by increasing awareness of the importance of cardiac safety in drug development. Regulatory bodies emphasize the necessity of herg screening to mitigate risks associated with drug-induced arrhythmias. This heightened focus on patient safety has led to a surge in demand for advanced screening technologies and methodologies. Furthermore, the presence of a robust pharmaceutical sector in South Korea contributes to the expansion of this market, as companies seek to comply with stringent regulatory requirements while ensuring the efficacy and safety of their products. In addition, the herg screening market benefits from ongoing research and development initiatives aimed at enhancing screening techniques. Collaborations between academic institutions and industry players are fostering innovation, leading to the introduction of novel assays and high-throughput screening methods. As the market evolves, it appears that the integration of artificial intelligence and machine learning into herg screening processes may further streamline operations and improve accuracy. Overall, the herg screening market in South Korea is poised for continued advancement, reflecting the nation's commitment to maintaining high standards in drug safety and efficacy.

    Regulatory Compliance and Safety Standards

    The herg screening market is significantly influenced by stringent regulatory frameworks that mandate comprehensive cardiac safety assessments. South Korean authorities prioritize the evaluation of drug candidates for herg channel inhibition, ensuring that new pharmaceuticals meet established safety criteria. This regulatory landscape drives pharmaceutical companies to invest in advanced herg screening technologies to comply with these requirements.

    Technological Advancements in Screening Methods

    Recent innovations in herg screening methodologies are reshaping the market landscape. The adoption of high-throughput screening techniques and automated systems enhances the efficiency and accuracy of herg assessments. South Korean firms are increasingly leveraging these advancements to expedite drug development processes while minimizing potential cardiac risks associated with new therapies.

    Collaborative Research Initiatives

    Collaborations between academic institutions and industry stakeholders are fostering significant advancements in the herg screening market. These partnerships aim to develop novel screening assays and improve existing methodologies. In South Korea, such collaborative efforts are likely to enhance the overall quality of herg screening, ultimately contributing to safer drug development practices.

    South Korea hERG Screening Market Drivers

    Increased Investment in Drug Development

    The herg screening market is benefiting from increased investment in drug development within South Korea. As pharmaceutical companies strive to bring innovative therapies to market, the need for comprehensive safety assessments has become paramount. In 2025, the total expenditure on drug development is expected to exceed $2 billion, with a significant portion allocated to herg screening. This trend indicates a growing recognition of the importance of early-stage safety evaluations in the drug development process. Consequently, the herg screening market is likely to expand as companies seek to mitigate risks associated with drug candidates. Enhanced collaboration between academia and industry is also anticipated, fostering advancements in herg screening methodologies and technologies, which may further drive market growth.

    Rising Demand for Cardiac Safety Testing

    The herg screening market in South Korea is experiencing a notable increase in demand for cardiac safety testing. This surge is primarily driven by the growing awareness of the risks associated with drug-induced arrhythmias. Regulatory bodies are emphasizing the importance of thorough cardiac safety evaluations, leading to a heightened focus on herg screening. In 2025, the market is projected to reach approximately $50 million, reflecting a compound annual growth rate (CAGR) of around 8%. Pharmaceutical companies are increasingly investing in herg screening technologies to ensure compliance with safety regulations, thereby propelling the market forward. As the industry evolves, the integration of advanced screening methods is likely to enhance the accuracy and efficiency of cardiac safety assessments, further solidifying the herg screening market's position in the broader pharmaceutical landscape.

    Collaboration Between Industry and Academia

    Collaboration between industry and academia is emerging as a key driver for the herg screening market in South Korea. Partnerships between pharmaceutical companies and research institutions are fostering innovation and advancing screening methodologies. In 2025, it is anticipated that collaborative research initiatives will account for nearly 25% of herg screening projects, enhancing the quality and reliability of testing. These collaborations often lead to the development of novel screening technologies and improved data analysis techniques, which can significantly impact drug safety evaluations. As the herg screening market continues to evolve, such partnerships are likely to play a crucial role in addressing the challenges associated with cardiac safety assessments, ultimately benefiting both the industry and public health.

    Technological Integration in Screening Processes

    Technological integration is transforming the herg screening market in South Korea. The adoption of high-throughput screening technologies and automated systems is streamlining the testing process, allowing for faster and more accurate results. In 2025, it is estimated that around 30% of herg screening tests will utilize automated platforms, significantly improving efficiency. This shift towards automation not only reduces labor costs but also enhances the reproducibility of results, which is crucial for regulatory compliance. As the industry embraces these technological advancements, the herg screening market is likely to witness substantial growth. Furthermore, the incorporation of artificial intelligence and machine learning in data analysis may provide deeper insights into drug interactions, potentially revolutionizing the screening landscape.

    Growing Regulatory Pressure for Safety Assessments

    The herg screening market is increasingly influenced by growing regulatory pressure for safety assessments in South Korea. Regulatory agencies are mandating comprehensive evaluations of drug candidates to ensure patient safety, particularly concerning cardiac risks. This trend is evident in the tightening of guidelines surrounding herg screening, which necessitates more rigorous testing protocols. In 2025, it is projected that compliance costs for pharmaceutical companies will rise by approximately 15%, prompting a greater reliance on herg screening services. As a result, the market is expected to expand as companies prioritize adherence to these regulations. The emphasis on safety assessments is likely to drive innovation in herg screening methodologies, fostering a more robust and reliable market.

    Market Segment Insights

    HERG

    The South Korea hERG screening Market showcases a growing focus on the Type segmentation, particularly with regard to Gene KCNH2 and Mutant KCNH2, both of which are crucial in assessing cardiac safety during drug development. The Gene KCNH2 plays a key role in encoding the potassium ion channel responsible for the cardiac repolarization process, and researchers continue to emphasize its importance in predicting drug-induced arrhythmias. The prevalence of congenital long QT syndrome due to mutations in the KCNH2 gene in South Korea highlights the necessity of thorough screening.

    On the other hand, Mutant KCNH2, which addresses various genetic alterations affecting the ion channel function, has emerged as a focal point in the context of personalized medicine. The demand for targeted therapies necessitates robust screening techniques that can accurately identify and characterize these mutations. As South Korea aims to enhance its position in the global pharmaceutical landscape, advancements in hERG screening technologies pertaining to these specific types can drive significant improvements in drug safety profiles. 

    ,

    Furthermore, the increasing awareness of the genetic underpinnings of cardiac conditions within medical communities is fostering more in-depth investigations into the implications of KCNH2 variants, indicating a trend toward integrating genetic insights into comprehensive hERG screening methods.Overall, the significance of Gene KCNH2 and Mutant KCNH2 in the South Korea hERG screening Market underscores their essential role in advancing both safety and efficacy in therapeutic drug development.

    Source: Primary Research, Secondary Research, Market Research Future Database, and Analyst Review

    HERG

    The South Korea hERG screening Market, particularly the Ion Channel segment, plays a critical role in drug development, especially in assessing cardiac safety profiles. Voltage-gated ion channels are essential in regulating electrical impulses across membranes and are significant for understanding arrhythmias and other cardiac conditions. These channels dominate the landscape due to their direct association with numerous cardiovascular diseases, making them a key focus for pharmaceutical research. On the other hand, ligand-gated ion channels also contribute significantly to the market, acting as crucial mediators in neurotransmission and other physiological processes.

    The rising emphasis on precision medicine and tailored therapies enhances the importance of these channels in screening and therapeutic applications. The South Korean government supports advancements in biotechnology, which fuels innovation within the hERG screening Market, positioning it for sustained growth. As research and development initiatives continue to evolve in the region, the demand for comprehensive hERG screening solutions tied to Ion Channel dynamics is likely to increase.

    HERG

    The South Korea hERG screening Market is poised to experience significant growth driven by the increasing demand for safer therapeutic agents. Within the Application domain, the landscape is characterized by diverse areas, including Antiarrhythmic, Antipsychotic, and Antibiotics, each playing a crucial role in enhancing drug safety profiles. The Antiarrhythmic segment is particularly significant as it focuses on drugs that manage irregular heartbeats, thereby requiring rigorous hERG assessments to mitigate potential cardiac risks. The Antipsychotic application area is also noteworthy due to the critical need to evaluate the effects of these medications on cardiac repolarization, impacting patient safety and therapeutic efficacy.

    Antibiotics, traditionally associated with infections, are now under scrutiny to prevent adverse cardiac effects, highlighting a growing trend toward comprehensive drug evaluations. The 'Others' category captures additional applications that are shaping market dynamics. As South Korea emphasizes pharmaceutical innovation and regulatory compliance, investing in hERG screening emerges as essential for reducing risks associated with drug development and improving overall patient safety. This robust focus on rigorous safety assessment reflects the evolving priorities within the South Korea hERG screening Market industry.

    South KoreahERG screening Market

    Get more detailed insights about South Korea hERG Screening Market

    Key Players and Competitive Insights

    The herg screening market is characterized by a competitive landscape that is increasingly shaped by innovation, strategic partnerships, and a focus on regulatory compliance. Key players such as Thermo Fisher Scientific (US), Charles River Laboratories (US), and Eurofins Scientific (LU) are at the forefront, leveraging their extensive expertise to enhance their service offerings. These companies appear to be strategically positioned to capitalize on the growing demand for herg screening services, driven by the rising need for drug safety assessments and regulatory requirements. Their operational focus on technological advancements and customer-centric solutions seems to collectively enhance the competitive environment, fostering a climate of continuous improvement and adaptation.

    In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance efficiency and responsiveness to market demands. The market structure appears moderately fragmented, with several players vying for market share, yet the influence of major companies remains substantial. This dynamic suggests that while competition is fierce, the presence of established firms provides a stabilizing effect, allowing for collaborative opportunities that can benefit the entire sector.

    In October 2025, Thermo Fisher Scientific (US) announced the launch of a new high-throughput herg screening platform designed to accelerate drug development timelines. This strategic move is likely to enhance their competitive edge by providing clients with faster and more reliable screening results, thereby addressing a critical need in the pharmaceutical industry. The introduction of this platform may also signify a shift towards more automated and efficient processes in herg screening, aligning with broader trends in laboratory automation.

    In September 2025, Charles River Laboratories (US) expanded its herg screening capabilities through a partnership with a leading biotechnology firm. This collaboration is expected to enhance their service offerings and provide clients with integrated solutions that combine herg screening with other preclinical services. Such strategic alliances may indicate a trend towards comprehensive service packages that cater to the evolving needs of pharmaceutical companies, thereby positioning Charles River as a more attractive partner in drug development.

    In August 2025, Eurofins Scientific (LU) acquired a specialized herg screening laboratory in South Korea, which is anticipated to bolster their presence in the Asia-Pacific region. This acquisition not only expands their geographical footprint but also enhances their technical capabilities, allowing them to offer localized services that meet specific regulatory requirements. The strategic importance of this move lies in Eurofins' ability to tap into the growing demand for herg screening in the region, potentially increasing their market share and reinforcing their competitive position.

    As of November 2025, current trends in the herg screening market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) into testing processes. Strategic alliances among key players are shaping the landscape, fostering innovation and enhancing service delivery. Looking ahead, it appears that competitive differentiation will evolve from traditional price-based competition to a focus on technological innovation, reliability in supply chains, and the ability to meet stringent regulatory standards. This shift may ultimately redefine how companies position themselves in the market, emphasizing the importance of adaptability and forward-thinking strategies.

    Key Companies in the South Korea hERG Screening Market market include

    Industry Developments

    The South Korea hERG screening Market has seen significant activity recently. In August 2023, Medytox announced advancements in their hERG channel screening capabilities, enhancing drug safety evaluations, aligning with international standards. Additionally, in September 2023, Samsung Biologics collaborated with Yuhan Corporation for joint Research and Development initiatives focusing on hERG assays to expedite the drug discovery process, which has been a part of a larger shift towards innovative screening methods in the country. Moreover, in October 2023, Celltrion and Hanmi Pharmaceutical partnered to leverage their combined expertise in drug development and hERG screening, aiming to improve patient safety outcomes. 

    Furthermore, growth in market valuation continues with Korean Cancer Society reporting that the overall funding towards hERG screening technologies has increased by 20% since 2021, positively impacting companies like LG Chem and SK Biopharmaceuticals, which are now looking to invest further in the development of advanced screening techniques. In the last two years, notable investments by Daewoong Pharmaceutical in HERG-related technologies have also driven the market's evolution, underlining its increasing importance within the pharmaceutical landscape of South Korea.

    South Koreah ERG screening Market Segmentation Insights

    hERG Screening Market Type Outlook

      • Gene KCNH2
      • Mutant KCNH2

    hERG Screening Market Ion Channel Outlook

      • Voltage Gated
      • Ligand Gated

    hERG Screening Market Application Outlook

      • Antiarrhythmic
      • Antipsychotic
      • Antibiotics
      • Others

    Future Outlook

    South Korea hERG Screening Market Future Outlook

    The herg screening market is projected to grow at 11.04% CAGR from 2024 to 2035, driven by technological advancements, regulatory demands, and increasing drug development activities.

    New opportunities lie in:

    • Development of AI-driven herg screening technologies for enhanced accuracy.
    • Expansion of herg screening services to biotech startups and SMEs.
    • Partnerships with pharmaceutical companies for integrated herg testing solutions.

    By 2035, the herg screening market is expected to achieve substantial growth and innovation.

    Market Segmentation

    South Korea hERG Screening Market Type Outlook

    • Gene KCNH2
    • Mutant KCNH2

    South Korea hERG Screening Market Application Outlook

    • Antiarrhythmic
    • Antipsychotic
    • Antibiotics
    • Others

    South Korea hERG Screening Market Ion Channel Outlook

    • Voltage Gated
    • Ligand Gated

    Report Scope

    MARKET SIZE 2024 28.0(USD Million)
    MARKET SIZE 2025 31.09(USD Million)
    MARKET SIZE 2035 88.6(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 11.04% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Thermo Fisher Scientific (US), Charles River Laboratories (US), Eurofins Scientific (LU), Celerion (US), CROMSOURCE (IT), Celerion (US), Inotiv (US), Celerion (US)
    Segments Covered Type, Ion Channel, Application
    Key Market Opportunities Advancements in automated herg screening technologies enhance drug safety and regulatory compliance in South Korea.
    Key Market Dynamics Rising regulatory scrutiny drives demand for advanced human ether-a-go-go related gene screening technologies in South Korea.
    Countries Covered South Korea

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    FAQs

    What is the expected market size of the South Korea HERG Screening Market in 2024?

    The South Korea HERG Screening Market is expected to be valued at 22.4 million USD in 2024.

    What will the market value be by 2035?

    By 2035, the South Korea HERG Screening Market is projected to reach a value of 83.6 million USD.

    What is the expected compound annual growth rate (CAGR) for the market from 2025 to 2035?

    The expected CAGR for the South Korea HERG Screening Market from 2025 to 2035 is 12.719%.

    What is the market size for the Gene KCNH2 segment in 2024?

    The Gene KCNH2 segment of the South Korea HERG Screening Market is valued at 10.5 million USD in 2024.

    What will the market value for the Gene KCNH2 segment be by 2035?

    By 2035, the Gene KCNH2 segment is expected to grow to 39.4 million USD.

    How much is the Mutant KCNH2 segment valued at in 2024?

    The Mutant KCNH2 segment of the market is valued at 11.9 million USD in 2024.

    What is the projected market size for the Mutant KCNH2 segment by 2035?

    The Mutant KCNH2 segment is projected to reach a value of 44.2 million USD by 2035.

    Who are the key players in the South Korea HERG Screening Market?

    Key players in the market include Medytox, Samsung Biologics, and SK Biopharmaceuticals among others.

    What are the main growth drivers for the South Korea HERG Screening Market?

    Growing research initiatives and advancements in biotechnology are primary growth drivers for the market.

    What are the major challenges facing the HERG Screening Market in South Korea?

    Challenges include high regulatory hurdles and the need for advanced technological integration.

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