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Splenomegaly Therapeutics Market Research Report: By Type of Splenomegaly (Myeloproliferative Neoplasm Associated Splenomegaly, Hepatic Disorders Associated Splenomegaly, Hemolytic Disorders Associated Splenomegaly, Infectious Disorders Associated Splenomegaly, Other Splenomegaly), By Treatment Type (Splenectomy, Radiation Therapy, Chemotherapy, Targeted Therapy, Other Treatments), By End User (Hospitals, Clinics, Academic and Research Institutes, Pharmaceutical and Biotechnology Companies) and By Regional (North America, Europe, South Amer


ID: MRFR/HC/26165-HCR | 100 Pages | Author: Rahul Gotadki| November 2024

Global Splenomegaly Therapeutics Market Overview


As per MRFR analysis, the Splenomegaly Therapeutics Market Size was estimated at 1.79 (USD Billion) in 2022. 

The Splenomegaly Therapeutics Market Industry is expected to grow from 1.89(USD Billion) in 2023 to 3.2 (USD Billion) by 2032. The Splenomegaly Therapeutics Market CAGR (growth rate) is expected to be around 6.0% during the forecast period (2024 - 2032).


Key Splenomegaly Therapeutics Market Trends Highlighted


The Splenomegaly Therapeutics market is witnessing steady growth, driven by the increasing prevalence of splenomegaly and the unmet medical needs in its treatment. Key market drivers include the rise in chronic liver diseases, such as cirrhosis and portal hypertension, which are the primary causes of splenomegaly. Moreover, the growing geriatric population, susceptible to splenomegaly, is further fueling the market growth. The advent of novel therapeutic modalities, including targeted therapies and immunomodulatory agents, is creating opportunities for innovation and improved patient outcomes. Recent trends in the market include the increasing adoption of minimally invasive procedures and the emergence of precision medicine approaches for personalized treatment strategies. The market is expected to continue its upward trajectory in the coming years, driven by these factors and the continuous advancements in Splenomegaly Therapeutics.


Splenomegaly Therapeutics Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Splenomegaly Therapeutics Market Drivers


Rising Prevalence of Hematological Disorders


The rising prevalence of hematological disorders, such as leukemia, lymphoma, and myelofibrosis, is a major driver of the growth of the Splenomegaly Therapeutics Market. Splenomegaly is a common complication of hematological disorders, and it can lead to a range of symptoms, including abdominal pain, fatigue and weight loss. As the prevalence of hematological disorders continues to increase, so too will the demand for splenomegaly therapeutics. The increasing prevalence of hematological disorders is due to a number of factors, including the aging population, the rise in chronic diseases, and the growing use of chemotherapy and radiation therapy.As the population ages, the risk of developing hematological disorders increases. Chronic diseases, such as HIV/AIDS and hepatitis C, can also lead to the development of hematological disorders. Chemotherapy and radiation therapy, which are used to treat cancer, can also damage the bone marrow and lead to the development of hematological disorders. The rising prevalence of hematological disorders is a major challenge for healthcare systems around the world.Splenomegaly is a serious complication of hematological disorders, and it can lead to a range of health problems. The development of new and effective splenomegaly therapeutics is essential to improving the quality of life for patients with hematological disorders.


Technological Advancements


Technological advancements are another major driver of the growth of the Splenomegaly Therapeutics Market. Technological advancements have led to the development of new drugs and therapies that have significantly improved the treatment of splenomegaly. For example, tyrosine kinase inhibitors have been developed to treat chronic myeloid leukemia. These are targeted therapies that block the growth of CML cells. As such, they have helped bring the survival rates of patients with CML to almost 90 percent.Furthermore, new surgical techniques have also been developed as a result of technological advancements. For instance, laparoscopic splenectomy is a minimally invasive technique for removing the spleen. This technique is less invasive than the traditional open surgery. It also has a shorter recovery time. In the foreseeable future, technological advancements will continue to drive the growth of the Splenomegaly Therapeutics Market. The development of new and more effective drugs and therapies is likely to continue to bring improvement to the treatment of the medical condition.


Growing Awareness of Splenomegaly


Another significant factor contributing to the increase in the demand for the products and the expansion of the Splenomegaly Therapeutics Market is the growing awareness of the condition. It should be noted that splenomegaly is an asymptomatic condition and is hard to diagnose. However, as the level of awareness of the disease increases, more people are diagnosed with the disorder, leading to the growth of demand for the therapeutics. The growing awareness of the disease is determined by a range of factors: the increasing occurrence of hematological disorders, the development of new diagnostic tools, and the expanded use of social media.To be more specific, in recent years, the prevalence of hematological disorders has markedly grown, which has led to an increased number of splenomegaly diagnoses. Besides, the expanded use of ultrasound and MRI techniques has allowed the diagnosis of the disease more effectively. Finally, the increased use of social media has been instrumental in boosting the levels of knowledge about the disease and its symptoms. Therefore, the described trend should be seen as quite beneficial since it provides a premise for the increasing number of people with the condition to be diagnosed and be provided the relevant adequate treatments.


Splenomegaly Therapeutics Market Segment Insights


Splenomegaly Therapeutics Market Type of Splenomegaly Insights


The Splenomegaly Therapeutics Market is segmented based on the type of splenomegaly into myeloproliferative neoplasm-associated splenomegaly, hepatic disorders-associated splenomegaly, hemolytic disorders-associated splenomegaly, infectious disorders-associated splenomegaly and other splenomegaly. Among these, the myeloproliferative neoplasm-associated splenomegaly segment held the largest market share in 2023 and is expected to maintain its dominance throughout the forecast period. The growth of this segment can be attributed to the increasing prevalence of myeloproliferative neoplasms, such as chronic myeloid leukemia and myelofibrosis, which are characterized by the overproduction of white blood cells and platelets, leading to splenomegaly.The hepatic disorders-associated splenomegaly segment is expected to witness a significant growth rate during the forecast period. This growth can be attributed to the rising incidence of chronic liver diseases, such as cirrhosis and non-alcoholic fatty liver disease, which can lead to portal hypertension and splenomegaly. The hemolytic disorders-associated splenomegaly segment is also expected to exhibit steady growth, driven by the increasing prevalence of autoimmune hemolytic anemia and sickle cell disease, which cause the destruction of red blood cells and subsequent splenomegaly.The infectious disorders-associated splenomegaly segment is expected to grow at a moderate pace during the forecast period. This growth can be attributed to the increasing prevalence of infectious diseases, such as malaria, tuberculosis and HIV/AIDS, which can lead to splenomegaly. The other splenomegaly segment is expected to experience the slowest growth rate due to the relatively lower prevalence of other causes of splenomegaly, such as Gaucher disease and Niemann-Pick disease.


Splenomegaly Therapeutics Market Type of Splenomegaly Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Splenomegaly Therapeutics Market Treatment Type Insights


The Splenomegaly Therapeutics Market is segmented by Treatment Type into Splenectomy, Radiation Therapy, Chemotherapy, Targeted Therapy and Other Treatments. In 2023, Splenectomy held the largest market share of 35.0%, and it is expected to continue its dominance throughout the forecast period. Splenectomy is a surgical procedure to remove the spleen, which is commonly performed to treat conditions such as splenomegaly, trauma, and certain types of cancer. Radiation Therapy is another major treatment option for splenomegaly, accounting for a market share of 28.2% in 2023.Radiation Therapy uses high-energy radiation to shrink or destroy the spleen and is often used in combination with other treatments. Chemotherapy is a common systemic treatment that uses cytotoxic drugs to kill cancer cells, and it is often used to treat splenomegaly caused by certain types of cancer. In 2023, Chemotherapy held a market share of 22.5%. Targeted Therapy is a newer system of treatment for splenomegaly that uses drugs that target the specific abnormalities present in the condition. In 2023, it accounted for 10.3% of the market share.Other Treatments for splenomegaly include lifestyle changes, medication and supportive care. They are primarily used alongside other treatment types to ensure that symptoms are managed effectively and to improve patient outcomes.


Splenomegaly Therapeutics Market End User Insights


Hospitals dominate the end-user segment of the Splenomegaly Therapeutics Market due to the high prevalence of patients with splenomegaly seeking treatment in these settings. The presence of advanced medical facilities, skilled healthcare professionals, and comprehensive diagnostic and treatment options in hospitals makes them the preferred choice for patients with splenomegaly. In 2023, the hospital segment accounted for approximately 60% of the Splenomegaly Therapeutics Market revenue, and this dominance is expected to continue in the coming years.Clinics, academic and research institutes, and pharmaceutical and biotechnology companies also contribute to the market growth, with each segment playing a specific role in the development, evaluation and commercialization of splenomegaly therapeutics.


Splenomegaly Therapeutics Market Regional Insights


The Splenomegaly Therapeutics Market is segmented into North America, Europe, Asia-Pacific, South America, Middle East and Africa. North America is the largest regional market for splenomegaly therapeutics, accounting for over 40% of the global market in 2023. The market in North America is driven by the high prevalence of splenomegaly, the presence of major pharmaceutical companies, and favorable reimbursement policies. Europe is the second-largest regional market for splenomegaly therapeutics, accounting for over 30% of the global market in 2023.The market in Europe is driven by the high prevalence of splenomegaly, the presence of major pharmaceutical companies, and favorable reimbursement policies. The Asia-Pacific region is the fastest-growing regional market for splenomegaly therapeutics, with a CAGR of over 7% during the forecast period. The market in the Asia-Pacific region is driven by the increasing prevalence of splenomegaly, the rising disposable income, and the growing awareness of splenomegaly treatments.


Splenomegaly Therapeutics Market Regional Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Splenomegaly Therapeutics Market Key Players And Competitive Insights


The major players in this industry, Splenomegaly Therapeutics Market, are making continuous efforts to get an edge over the competitors. They are investing a huge amount of money in R D and are coming up with innovative new drugs that are more effective and have fewer side effects. The global market is expected to see a major upward trend in the upcoming years due to the launch of a number of new products. The leading players in the Splenomegaly Therapeutics Market are also expanding their global presence through strategic alliances and acquisitions that are further acting as a growth driver for them. The global Splenomegaly Therapeutics Market competitive market is expected to remain highly fragmented in the upcoming years.The leading player in the market is Bristol Myers Squibb. The company has a strong product suite for the treatment of splenomegaly, which includes Revlimid and Pomalyst. Bristol Myers Squibb is also working on further developing the market with their R-D project, with a number of other products in the pipeline.A competitor to Bristol Myers Squibb in the market is Celgene, which also has a strong product suite for the treatment of splenomegaly, which includes Revlimid and Pomalyst. Celgene is also focusing on RD and has a number of other drugs in the pipeline.


Key Companies in the Splenomegaly Therapeutics Market Include



  • Astellas Pharma

  • Calithera Biosciences

  • Aduro Biotech

  • Celgene

  • Amgen

  • Alnylam Pharmaceuticals

  • Bayer

  • AbbVie

  • Bristol Myers Squibb

  • Gilead Sciences

  • Incyte

  • Agios Pharmaceuticals

  • ArQule

  • Janssen Pharmaceuticals

  • Daiichi Sankyo


Splenomegaly Therapeutics Market Industry Developments


The Splenomegaly Therapeutics Market is poised to witness steady growth over the forecast period. Recent advancements in research and development have led to the emergence of novel therapies, including targeted drugs and immunotherapies, offering promising treatment options for patients. Key players are actively involved in clinical trials and strategic collaborations to expand their product portfolios and gain a competitive edge. Moreover, increasing awareness about the condition and its management is expected to drive market growth in the coming years. The market is also likely to benefit from the growing adoption of minimally invasive procedures and personalized medicine approaches. However, factors such as high treatment costs and limited access to healthcare in certain regions may pose challenges to market expansion.


Splenomegaly Therapeutics Market Segmentation Insights



  • Splenomegaly Therapeutics Market Type of Splenomegaly Outlook

    • Myeloproliferative Neoplasm Associated Splenomegaly

    • Hepatic Disorders Associated Splenomegaly

    • Hemolytic Disorders Associated Splenomegaly

    • Infectious Disorders Associated Splenomegaly

    • Other Splenomegaly




 



  • Splenomegaly Therapeutics Market Treatment Type Outlook

    • Splenectomy

    • Radiation Therapy

    • Chemotherapy

    • Targeted Therapy

    • Other Treatments




 



  • Splenomegaly Therapeutics Market End User Outlook

    • Hospitals

    • Clinics

    • Academic and Research Institutes

    • Pharmaceutical and Biotechnology Companies




 



  • Splenomegaly Therapeutics Market Regional Outlook

    • North America

    • Europe

    • South America

    • Asia Pacific

    • Middle East and Africa



Report Attribute/Metric Details
Market Size 2022 1.79(USD Billion)
Market Size 2023 1.89(USD Billion)
Market Size 2032 3.2(USD Billion)
Compound Annual Growth Rate (CAGR) 6.0% (2024 - 2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024 - 2032
Historical Data 2019 - 2023
Market Forecast Units USD Billion
Key Companies Profiled Astellas Pharma, Calithera Biosciences, Aduro Biotech, Celgene, Amgen, Alnylam Pharmaceuticals, Bayer, AbbVie, Bristol Myers Squibb, Gilead Sciences, Incyte, Agios Pharmaceuticals, ArQule, Janssen Pharmaceuticals, Daiichi Sankyo
Segments Covered Type of Splenomegaly, Treatment Type, End User, Regional
Key Market Opportunities Growing prevalence of liver diseases Increasing demand for personalized therapies Advancements in drug discovery technologies Government support for research and development Expanding healthcare infrastructure in emerging markets
Key Market Dynamics Increasing prevalence of chronic liver diseases Growing adoption of advanced diagnostic techniques Rising demand for minimally invasive procedures Technological advancements in drug development Government initiatives to support research and development
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The Splenomegaly Therapeutics Market size is estimated to be around USD 1.89 billion in 2023.

The Splenomegaly Therapeutics Market is projected to grow at a CAGR of 6.0% from 2024 to 2032.

North America is expected to hold the largest market share in the Splenomegaly Therapeutics Market in 2023.

The key application segments of the Splenomegaly Therapeutics Market include immune thrombocytopenia (ITP), myelodysplastic syndromes (MDS), and Gaucher disease.

The key competitors in the Splenomegaly Therapeutics Market include Novartis, Roche, Bristol-Myers Squibb and Merck Co.

The major factors driving the growth of the Splenomegaly Therapeutics Market include the rising prevalence of splenomegaly, increasing healthcare expenditure, and growing awareness of splenomegaly.

The challenges faced by the Splenomegaly Therapeutics Market include high cost of treatment, lack of reimbursement, and side effects associated with splenectomy.

The opportunities for the Splenomegaly Therapeutics Market include the development of new and more effective drugs, increasing awareness of splenomegaly, and growing demand for minimally invasive procedures.

The key trends in the Splenomegaly Therapeutics Market include the increasing use of targeted therapies, the development of combination therapies, and the growing adoption of personalized medicine.

The Splenomegaly Therapeutics Market is expected to reach a market size of around USD 3.2 billion by 2032.

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