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    Inflammatory Bowel Therapeutic Market

    ID: MRFR/HC/41954-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    Inflammatory Bowel Therapeutic Market Research Report By Therapeutic Class (Aminosalicylates, Corticosteroids, Immunomodulators, Biologics, Antibiotics), By Route of Administration (Oral, Injectable, Topical, Intravenous), By Indication (Ulcerative Colitis, Crohn's Disease, Indeterminate Colitis), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa)- Forecast to 2035

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    Inflammatory Bowel Therapeutic Market Summary

    As per MRFR analysis, the Inflammatory Bowel Therapeutic Market Size was estimated at 17.7 USD Billion in 2024. The Inflammatory Bowel Therapeutic industry is projected to grow from 18.3 USD Billion in 2025 to 25.49 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 3.37 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Inflammatory Bowel Therapeutic Market is experiencing a transformative shift towards advanced treatment modalities and personalized care.

    • The rise of biologics continues to dominate the market, particularly in North America, which remains the largest market for inflammatory bowel therapies.
    • Personalized medicine is gaining traction, with a notable focus on tailoring treatments to individual patient profiles in the Asia-Pacific region, the fastest-growing market.
    • Digital health integration is becoming increasingly prevalent, enhancing patient engagement and treatment adherence across various therapeutic segments.
    • The increasing prevalence of inflammatory bowel disease and advancements in drug development are driving market growth, particularly in the biologics and oral segments.

    Market Size & Forecast

    2024 Market Size 17.7 (USD Billion)
    2035 Market Size 25.49 (USD Billion)
    CAGR (2025 - 2035) 3.37%

    Major Players

    AbbVie (US), Johnson & Johnson (US), Bristol-Myers Squibb (US), Takeda Pharmaceutical (JP), Amgen (US), Gilead Sciences (US), Sanofi (FR), Merck & Co. (US), Celgene (US)

    Inflammatory Bowel Therapeutic Market Trends

    The Inflammatory Bowel Therapeutic Market is currently experiencing notable transformations driven by advancements in treatment modalities and a growing understanding of disease mechanisms. The increasing prevalence of inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, has prompted a surge in research and development efforts. Pharmaceutical companies are focusing on innovative therapies, including biologics and small molecules, which appear to offer improved efficacy and safety profiles. Furthermore, the integration of personalized medicine into treatment strategies suggests a shift towards more tailored approaches, potentially enhancing patient outcomes. In addition to therapeutic advancements, the Inflammatory Bowel Therapeutic Market is influenced by evolving patient demographics and healthcare policies. The rising awareness of inflammatory bowel diseases among healthcare professionals and patients alike indicates a growing demand for effective treatments. Moreover, the expansion of telemedicine and digital health solutions may facilitate better patient management and adherence to treatment regimens. As the market continues to evolve, stakeholders must remain vigilant to emerging trends and adapt their strategies accordingly to meet the needs of patients and healthcare systems.

    Rise of Biologics

    The Inflammatory Bowel Therapeutic Market is witnessing a significant shift towards biologic therapies. These treatments, which target specific components of the immune system, are gaining traction due to their ability to provide effective relief for patients with moderate to severe conditions. Biologics appear to offer a more targeted approach compared to traditional therapies, potentially leading to better long-term outcomes.

    Personalized Medicine

    The concept of personalized medicine is becoming increasingly relevant within the Inflammatory Bowel Therapeutic Market. Tailoring treatment plans based on individual patient profiles, including genetic and biomarker information, may enhance therapeutic efficacy. This trend suggests a move away from one-size-fits-all approaches, indicating a more nuanced understanding of disease pathology.

    Digital Health Integration

    The integration of digital health technologies into the Inflammatory Bowel Therapeutic Market is on the rise. Mobile applications and telehealth platforms are being utilized to improve patient engagement and adherence to treatment. This trend highlights the potential for technology to play a crucial role in managing chronic conditions, thereby enhancing overall patient care.

    The increasing prevalence of inflammatory bowel diseases globally necessitates innovative therapeutic approaches and comprehensive healthcare strategies to enhance patient outcomes.

    U.S. National Institutes of Health (NIH)

    Inflammatory Bowel Therapeutic Market Drivers

    Rising Awareness and Education

    The increasing awareness and education surrounding inflammatory bowel disease are pivotal in shaping the Inflammatory Bowel Therapeutic Market. Healthcare providers and patients are becoming more informed about the symptoms, diagnosis, and treatment options available for IBD. This heightened awareness is leading to earlier diagnosis and treatment initiation, which is crucial for managing the disease effectively. Patient advocacy groups and educational campaigns are playing a vital role in disseminating information, thereby empowering patients to seek medical attention sooner. As a result, the demand for therapeutic interventions is likely to rise, as more individuals are diagnosed and treated for IBD. This trend is expected to stimulate growth in the Inflammatory Bowel Therapeutic Market, as pharmaceutical companies respond to the increasing need for effective therapies.

    Advancements in Drug Development

    Recent advancements in drug development methodologies are significantly influencing the Inflammatory Bowel Therapeutic Market. The emergence of novel therapeutic agents, particularly biologics and targeted therapies, has transformed treatment paradigms for IBD. For instance, the introduction of monoclonal antibodies has provided new avenues for managing severe cases of Crohn's disease and ulcerative colitis. Additionally, the integration of precision medicine approaches allows for tailored treatments based on individual patient profiles, enhancing therapeutic efficacy. The market is witnessing a surge in clinical trials aimed at evaluating new compounds, with hundreds of studies currently underway. This robust pipeline of investigational drugs is expected to expand treatment options and improve patient outcomes, thereby driving growth in the Inflammatory Bowel Therapeutic Market.

    Regulatory Support for New Therapies

    Regulatory support for the approval of new therapies is a significant factor influencing the Inflammatory Bowel Therapeutic Market. Regulatory agencies are increasingly recognizing the need for expedited pathways for innovative treatments that address unmet medical needs in IBD. Initiatives such as breakthrough therapy designations and fast-track approvals are encouraging pharmaceutical companies to invest in research and development. This supportive regulatory environment is likely to accelerate the introduction of novel therapies into the market, providing patients with more options for managing their condition. As new treatments gain approval, the Inflammatory Bowel Therapeutic Market is expected to experience substantial growth, driven by the influx of innovative products that enhance patient care.

    Technological Innovations in Treatment Delivery

    Technological innovations in treatment delivery systems are emerging as a key driver in the Inflammatory Bowel Therapeutic Market. The development of advanced drug delivery mechanisms, such as oral biologics and sustained-release formulations, is enhancing the efficacy and convenience of IBD treatments. These innovations aim to improve patient adherence to therapy, which is often a challenge in chronic conditions like IBD. Furthermore, the integration of digital health technologies, including mobile applications and telemedicine, is facilitating better management of the disease. Patients can now monitor their symptoms and treatment responses more effectively, leading to improved outcomes. As these technologies continue to evolve, they are likely to reshape the therapeutic landscape, driving growth in the Inflammatory Bowel Therapeutic Market.

    Increasing Prevalence of Inflammatory Bowel Disease

    The rising incidence of inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a primary driver of the Inflammatory Bowel Therapeutic Market. Recent estimates indicate that the prevalence of IBD has been steadily increasing, with millions affected worldwide. This growing patient population necessitates the development and availability of effective therapeutic options. As healthcare systems strive to manage this chronic condition, the demand for innovative treatments, including biologics and small molecules, is likely to surge. Furthermore, the economic burden associated with IBD management, which can exceed thousands of dollars annually per patient, underscores the urgency for effective therapies. Consequently, pharmaceutical companies are increasingly investing in research and development to address this unmet need, thereby propelling the Inflammatory Bowel Therapeutic Market forward.

    Market Segment Insights

    By Therapeutic Class: Biologics (Largest) vs. Aminosalicylates (Fastest-Growing)

    In the Inflammatory Bowel Therapeutic Market, the segment distribution reveals that Biologics hold the largest market share, driven by their advanced efficacy and targeted action against inflammatory bowel diseases. In contrast, Aminosalicylates are rapidly gaining traction, appealing to patients seeking effective but less aggressive treatment options. The other segments, including Corticosteroids and Immunomodulators, maintain a more stable presence but do not exhibit the same growth potential as these leading classes. As patient preferences shift, the competition among these classes intensifies, reflecting changes in treatment paradigms. Looking at growth trends, the rise of Biologics has been propelled by increased awareness and acceptance of personalized medicine, offering tailored solutions to patients with Inflammatory Bowel Disorders. Meanwhile, Aminosalicylates are seeing faster growth due to their long-established history of effectiveness, alongside new formulations and favorable side effect profiles. The market is influenced by ongoing clinical research, leading to innovative therapies that better meet the evolving needs of patients and healthcare providers alike.

    Biologics (Dominant) vs. Aminosalicylates (Emerging)

    Biologics represent the dominant therapeutic class in the Inflammatory Bowel Therapeutic Market, characterized by their ability to target specific components of the immune system. These medications, which include anti-TNF agents and integrin inhibitors, have revolutionized the management of severe conditions such as Crohn's Disease and Ulcerative Colitis. Their precision and efficacy have led to a growing acceptance among patients and healthcare professionals, positioning them as first-line treatments for moderate to severe cases. On the other hand, Aminosalicylates, while historically seen as the foundational therapy for milder forms of these diseases, are emerging as a strong competitor due to newer formulations and low side effect profiles. This resurgence is driven by a focus on step-up therapy approaches, making them relevant in the treatment landscape. Their revaluation illustrates a shift toward balancing long-term efficacy and patient quality of life.

    By Route of Administration: Oral (Largest) vs. Injectable (Fastest-Growing)

    In the Inflammatory Bowel Therapeutic Market, the Route of Administration segment demonstrates a diverse distribution of market share. Oral administration leads the segment, favored by patients for its ease of use and non-invasive nature, resulting in significant adoption. Meanwhile, Injectable therapies are rapidly gaining traction, reflecting a shift towards more effective delivery mechanisms, particularly for biologic drugs. The increasing prevalence of inflammatory bowel diseases further fuels the demand for both administration routes. The growth trends within this segment underscore a notable shift in treatment approaches. Injectable treatments, particularly biologics, are recognized for their targeted action and efficacy, making them the fastest-growing route. As innovation propels the development of new therapies and patient adherence improves, demand for injectables is expected to rise sharply, complementing the established oral options. This dynamic illustrates the evolving landscape of inflammatory bowel disease management, balancing convenience with advanced therapeutic strategies.

    Oral (Dominant) vs. Injectable (Emerging)

    Oral administration remains the dominant route within the Inflammatory Bowel Therapeutic Market due to its established history, patient preference, and broad range of available therapies. It offers ease of use, which is particularly appealing for chronic conditions that require long-term management. Oral medications, ranging from traditional treatments to newer formulations, continue to play a crucial role in everyday treatment regimens. Conversely, injectables are emerging as a vital alternative, driven by advances in biologics and biosimilars. These therapies offer a more direct approach to managing symptoms and promoting remission, particularly for severe cases. As healthcare providers increasingly embrace personalized medicine, the injectable segment is poised for rapid growth, appealing to patients seeking targeted interventions.

    By Indication: Ulcerative Colitis (Largest) vs. Crohn's Disease (Fastest-Growing)

    The Inflammatory Bowel Therapeutic Market distribution among the indications reveals that Ulcerative Colitis holds a significant share due to its higher prevalence in diagnosed cases compared to Crohn's Disease and Indeterminate Colitis. Crohn's Disease, while not as prominent in total market share, is showing robust growth driven by increasing awareness and advances in therapeutic options. Indeterminate Colitis, though smaller, reflects a niche market with specific treatment needs.

    Ulcerative Colitis (Dominant) vs. Crohn's Disease (Emerging)

    Ulcerative Colitis is recognized as the dominant indication in the Inflammatory Bowel Therapeutic Market, characterized by its chronic inflammation of the colon and rectum. The availability of targeted therapies has solidified its position. Conversely, Crohn's Disease, marked by its ability to affect any part of the gastrointestinal tract, is emerging rapidly in terms of therapeutic advancements. Increased investments in research for Crohn's Disease treatments and patient-centric approaches are driving market dynamics, converting this segment into a focal point for pharmaceutical innovations.

    By Distribution Channel: Hospital Pharmacies (Largest) vs. Online Pharmacies (Fastest-Growing)

    The distribution of the Inflammatory Bowel Therapeutic Market among various channels shows that Hospital Pharmacies hold a significant share as the largest segment. Their pivotal role in patient management and direct access to specialized healthcare services support their dominance. In contrast, Online Pharmacies are emerging rapidly, adapting to patient convenience and digital transformation, thereby capturing an increasing share of the market.

    Hospital Pharmacies (Dominant) vs. Online Pharmacies (Emerging)

    Hospital Pharmacies are characterized by their robust integration within healthcare systems, providing specialized services such as medication compounding and patient counseling. This dominance enables them to cater efficiently to complex patient needs, particularly for those with severe conditions like inflammatory bowel diseases. On the other hand, Online Pharmacies are experiencing exponential growth driven by the convenience of home delivery, enhanced access to medications, and the ability to compare prices easily. Their emerging position is facilitated by technological advancements and changing consumer behaviors, making them a significant player in the market.

    Get more detailed insights about Inflammatory Bowel Therapeutic Market

    Regional Insights

    The inflammatory bowel therapeutic market demonstrated significant potential across various regional segments. North America led this segment, holding a market valuation of 7.5 USD Billion, and is projected to grow to 10.9 USD Billion by 2035, reflecting its majority holding in the industry due to advanced healthcare infrastructure and higher prevalence of inflammatory bowel diseases. Europe followed closely with a valuation of 5.0 USD Billion in 2024 and an expected rise to 7.2 USD Billion in 2035, underscoring its substantial contribution to the inflammatory bowel therapeutic market revenue.

    The Asia-Pacific (APAC) region, valued at 3.5 USD Billion in 2024, is anticipated to grow to 5.2 USD Billion by 2035, showcasing increasing awareness and healthcare investments. South America and the Middle East and Africa (MEA) held smaller market shares, valued at 1.5 USD Billion and 0.2 USD Billion in 2024, respectively, with significant growth opportunities as healthcare access improves. Understanding these regional dynamics was crucial for stakeholders aiming to tap into the evolving inflammatory bowel therapeutic market segmentation and capitalized on emerging trends.

    Inflammatory Bowel Therapeutic Market Region

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The inflammatory bowel therapeutic market is a rapidly evolving sector driven by an increasing prevalence of inflammatory bowel diseases such as Crohn's disease and ulcerative colitis. As the demand for effective treatment solutions continues to rise, various pharmaceutical companies are striving to innovate and expand their product offerings.

    The competitive landscape is characterized by collaboration, mergers and acquisitions, and strategic partnerships aimed at enhancing research capabilities and market reach. Companies are focusing on the development of biologics, small molecules, and novel therapies to improve patient outcomes.

    Moreover, heightened regulatory scrutiny and the necessity for robust clinical evidence are influencing the strategies employed by market players. This competitive environment is pivotal for driving advancements in treatment methodologies, ultimately benefiting patients and healthcare systems alike.

    Amgen has established a strong presence in the inflammatory bowel therapeutic market through its innovative approaches to treatment, focusing on biologics that target specific immune pathways. The company leverages advanced research and clinical development capabilities to enhance its product pipeline, making notable contributions through therapies that improve the quality of life for patients suffering from inflammatory bowel diseases.

    Amgen's extensive experience in biologics aids in its efficiency in delivering targeted therapies, which have been well-received in clinical settings. The firm's commitment to patient-centric solutions and strategic alliances with healthcare professionals further amplifies its credibility and effectiveness in this specialized market. Additionally, its robust commercial infrastructure allows Amgen to maximize the accessibility and distribution of its products, positioning it prominently among stakeholders in the inflammatory bowel disease space.

    Gilead Sciences has made significant strides in the inflammatory bowel therapeutic market, emphasizing its dedication to addressing unmet medical needs in gastrointestinal diseases. The company's innovative therapeutic strategies focus on developing treatments that are not only effective but also offer the potential for enhanced tolerability for patients. Gilead Sciences stands out due to its robust research and development initiative, which is complemented by partnerships with academic and clinical institutions to accelerate progress in inflammatory bowel disease therapies.

    Furthermore, Gilead's pipeline includes promising candidates that leverage novel mechanisms of action, presenting a competitive edge over conventional treatment options. With its strong emphasis on scientific rigor and commitment to advancing care, Gilead Sciences has effectively positioned itself as a key player in the inflammatory bowel therapeutic landscape, aiming to transform patient care and outcomes in this challenging therapeutic area.

    Key Companies in the Inflammatory Bowel Therapeutic Market market include

    Industry Developments

    • Q2 2024: Johnson & Johnson Receives FDA Approval for TREMFYA® (guselkumab) for the Treatment of Moderately to Severely Active Ulcerative Colitis Johnson & Johnson announced that the U.S. FDA approved TREMFYA® (guselkumab) for adults with moderately to severely active ulcerative colitis, marking the first IL-23 inhibitor approved for this indication.
    • Q2 2024: Pfizer Announces European Commission Approval of VELSIPITY® (etrasimod) for Adults with Moderately to Severely Active Ulcerative Colitis Pfizer received European Commission approval for VELSIPITY® (etrasimod), an oral, once-daily S1P receptor modulator, for the treatment of adults with moderately to severely active ulcerative colitis.
    • Q2 2024: Takeda Receives FDA Approval for EOHILIA™ (budesonide oral suspension) for Eosinophilic Esophagitis Takeda announced FDA approval of EOHILIA™ (budesonide oral suspension) for the treatment of eosinophilic esophagitis, expanding its gastrointestinal therapeutic portfolio.
    • Q2 2024: AbbVie Receives FDA Approval for SKYRIZI® (risankizumab-rzaa) for Moderately to Severely Active Crohn’s Disease in Pediatric Patients AbbVie announced FDA approval for SKYRIZI® (risankizumab-rzaa) for the treatment of moderately to severely active Crohn’s disease in pediatric patients aged 6 years and older.
    • Q3 2024: Eli Lilly to Acquire Morphic Holding for $3.2 Billion to Expand Inflammatory Bowel Disease Pipeline Eli Lilly announced an agreement to acquire Morphic Holding, a clinical-stage biopharmaceutical company focused on oral integrin therapies for inflammatory bowel disease, for $3.2 billion.
    • Q2 2024: Gilead and Galapagos Announce Strategic Partnership to Develop Filgotinib for Inflammatory Bowel Disease Gilead Sciences and Galapagos NV entered a strategic partnership to co-develop and commercialize filgotinib, a JAK1 inhibitor, for the treatment of inflammatory bowel disease in multiple global markets.
    • Q1 2024: Takeda Opens New Biologics Manufacturing Facility in Singapore to Support Global Supply of Gastrointestinal Therapies Takeda inaugurated a new biologics manufacturing facility in Singapore, aimed at increasing production capacity for its gastrointestinal and inflammatory bowel disease therapies.
    • Q2 2024: Prometheus Biosciences Raises $250 Million in IPO to Advance IBD Drug Pipeline Prometheus Biosciences completed a $250 million initial public offering to fund the development of its precision therapeutics pipeline for inflammatory bowel disease.
    • Q2 2024: Amgen Announces FDA Approval of Amjevita™ (adalimumab-atto), a Biosimilar to Humira®, for Ulcerative Colitis and Crohn’s Disease Amgen received FDA approval for Amjevita™ (adalimumab-atto), a biosimilar to Humira®, for the treatment of ulcerative colitis and Crohn’s disease in the United States.
    • Q1 2024: Arena Pharmaceuticals Appoints New Chief Medical Officer to Lead IBD Clinical Programs Arena Pharmaceuticals announced the appointment of a new Chief Medical Officer to oversee the company’s clinical development programs in inflammatory bowel disease.
    • Q3 2024: Bristol Myers Squibb and Sosei Heptares Announce Collaboration to Develop Novel Therapies for Inflammatory Bowel Disease Bristol Myers Squibb and Sosei Heptares entered a collaboration agreement to develop and commercialize novel therapies targeting inflammatory bowel disease.
    • Q2 2024: Pfizer and Syros Pharmaceuticals Announce Research Collaboration to Discover New Small Molecule Therapies for Inflammatory Bowel Disease Pfizer and Syros Pharmaceuticals announced a research collaboration to discover and develop new small molecule therapies for the treatment of inflammatory bowel disease.

    Future Outlook

    Inflammatory Bowel Therapeutic Market Future Outlook

    The Inflammatory Bowel Therapeutic Market is projected to grow at a 3.37% CAGR from 2024 to 2035, driven by increasing prevalence, innovative therapies, and enhanced patient management solutions.

    New opportunities lie in:

    • Development of personalized biologic therapies targeting specific patient profiles.
    • Expansion of telehealth services for remote patient monitoring and consultations.
    • Investment in AI-driven drug discovery platforms to accelerate therapeutic development.

    By 2035, the market is expected to achieve substantial growth, driven by innovation and strategic investments.

    Market Segmentation

    Inflammatory Bowel Therapeutic Market Indication Outlook

    • Ulcerative Colitis
    • Crohn's Disease
    • Indeterminate Colitis

    Inflammatory Bowel Therapeutic Market Therapeutic Class Outlook

    • Aminosalicylates
    • Corticosteroids
    • Immunomodulators
    • Biologics
    • Antibiotics

    Inflammatory Bowel Therapeutic Market Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Inflammatory Bowel Therapeutic Market Route of Administration Outlook

    • Oral
    • Injectable
    • Topical
    • Intravenous

    Report Scope

    MARKET SIZE 202417.7(USD Billion)
    MARKET SIZE 202518.3(USD Billion)
    MARKET SIZE 203525.49(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)3.37% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesAdvancements in biologics and personalized medicine enhance treatment options in the Inflammatory Bowel Therapeutic Market.
    Key Market DynamicsRising demand for biologics drives innovation and competition in the Inflammatory Bowel Therapeutic Market.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

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    FAQs

    What is the expected value of the Global Inflammatory Bowel Therapeutic Market in 2024?

    The Global Inflammatory Bowel Therapeutic Market is expected to be valued at 17.7 USD Billion in 2024.

    What is the projected market size of the Global Inflammatory Bowel Therapeutic Market in 2035?

    By 2035, the Global Inflammatory Bowel Therapeutic Market is projected to reach a value of 25.5 USD Billion.

    What is the expected CAGR for the Global Inflammatory Bowel Therapeutic Market from 2025 to 2035?

    The expected Compound Annual Growth Rate (CAGR) for the market from 2025 to 2035 is 3.37%.

    Which region is expected to hold the largest market share in 2024?

    North America is expected to dominate the market with a value of 7.5 USD Billion in 2024.

    What is the market size for Biologics within the Global Inflammatory Bowel Therapeutic Market in 2035?

    The market size for Biologics is anticipated to be 7.0 USD Billion by 2035.

    Who are the key players in the Global Inflammatory Bowel Therapeutic Market?

    Major players include Amgen, Gilead Sciences, Bristol-Myers Squibb, and AbbVie, among others.

    What will be the market size for Corticosteroids in 2035?

    The market for Corticosteroids is projected to reach 4.5 USD Billion in 2035.

    How much is the APAC region expected to grow in the Global Inflammatory Bowel Therapeutic Market by 2035?

    The APAC region is expected to reach a market value of 5.2 USD Billion by 2035.

    What is the market value for Immunomodulators in 2024?

    Immunomodulators are valued at 3.0 USD Billion in 2024.

    How much is the market for Antibiotics expected to grow from 2024 to 2035?

    The market for Antibiotics is expected to grow from 1.0 USD Billion in 2024 to 1.2 USD Billion in 2035.

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