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    Immortalized Cell Line Market

    ID: MRFR/LS/0267-CR
    130 Pages
    Rahul Gotadki
    August 2019

    Immortalized Cell Line Market Research Report Information by Method (Virus Induction, HTERT Expression, Inactivation of Tumor Suppression Genes and others), Application (Diagnostics, Drug Discovery, Vaccine Production, Tissue Engineering and Regenerative Medicines and others), End User (Pharmaceutical and Biopharmaceutical Companies, Contract Research Organizations and Research Laboratories) and Region (Americas, Europe, Asia-Pacific and Middle East & Africa) - Forecast till 2032

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    Immortalized Cell Line Market Research Report - Global Forecast till 2032 Infographic
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    Immortalized Cell Line Market Summary

    The Global Immortalized Cell Line Market is projected to grow from 4.51 USD Billion in 2024 to 9.18 USD Billion by 2035.

    Key Market Trends & Highlights

    Immortalized Cell Line Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 6.67% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 9.18 USD Billion, indicating robust growth.
    • In 2024, the market is valued at 4.51 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of immortalized cell lines due to their advantages in drug development is a major market driver.

    Market Size & Forecast

    2024 Market Size 4.51 (USD Billion)
    2035 Market Size 9.18 (USD Billion)
    CAGR (2025-2035) 6.67%

    Major Players

    Thermo Fisher Scientific (US), ATCC (American Type Culture Collection Inc.) (US), Valneva (France), Sartorius AG (Germany), Lonza Group, AG (Switzerland), Merck KGaA (Germany), Selexis SA (Switzerland), WuXi App Tec (China), European Collection of Authenticated Cell Cultures (ECACC) (Europe), Corning Incorporated (US)

    Immortalized Cell Line Market Trends

    The increasing demand for organ donation due to scarcity in the availability of organs is driving the need for artificially created biological cells. For instance, according to the US Department of Health & Human Services Organ Procurement and Transplantation Network (OPTN), as of November 2016, 121,678 patients were waiting for a life-saving organ transplant. This rising demand for an

    organ transplant

    is expected to drive the growth of the market during the forecast period. Additionally, increasing application in biotech and pharmaceutical companies and hospitals and rise in the patient population affected by cancer are likely to support market growth. On the other hand, the high cost of equipment and developing a stable strain of cell line and maintaining and preventing it from contamination is anticipated to hamper the market growth.

    The increasing demand for advanced therapeutic solutions and personalized medicine appears to be driving the growth of the immortalized cell line market, as these cell lines provide essential tools for drug discovery and development.

    National Institutes of Health (NIH)

    Immortalized Cell Line Market Drivers

    Market Growth Projections

    Rising Demand for Biopharmaceuticals

    The increasing demand for biopharmaceuticals is a primary driver of the Global Immortalized Cell Line Market Industry. As the biopharmaceutical sector expands, the need for reliable and consistent cell lines for drug development and production intensifies. Immortalized cell lines provide a stable and reproducible platform for research and manufacturing, which is crucial for the development of therapeutic proteins and monoclonal antibodies. In 2024, the market is projected to reach 4.51 USD Billion, reflecting the growing reliance on these cell lines in biopharmaceutical applications. This trend is likely to continue as the industry evolves, potentially leading to a market size of 9.18 USD Billion by 2035.

    Emerging Markets and Global Expansion

    Emerging markets are becoming increasingly important in the Global Immortalized Cell Line Market Industry. Countries in Asia-Pacific and Latin America are witnessing rapid growth in their biopharmaceutical sectors, driven by rising healthcare expenditures and increasing research activities. This expansion presents significant opportunities for the adoption of immortalized cell lines in these regions. As global players seek to establish a presence in these markets, the demand for reliable cell lines is expected to surge. This trend is likely to contribute to the overall growth of the market, as companies adapt their strategies to cater to the unique needs of emerging economies.

    Advancements in Cell Line Technologies

    Technological advancements in cell line development are significantly influencing the Global Immortalized Cell Line Market Industry. Innovations such as CRISPR-Cas9 gene editing and improved culture techniques enhance the efficiency and reliability of immortalized cell lines. These advancements enable researchers to create cell lines with specific genetic modifications, facilitating targeted drug discovery and personalized medicine approaches. As these technologies become more accessible, the market is expected to grow at a CAGR of 6.67% from 2025 to 2035. This growth is indicative of the increasing integration of advanced technologies in cell line research and development.

    Growing Focus on Personalized Medicine

    The shift towards personalized medicine is reshaping the Global Immortalized Cell Line Market Industry. Immortalized cell lines play a crucial role in understanding individual responses to therapies, allowing for the development of tailored treatment strategies. This focus on personalized approaches is driving research and development efforts, as pharmaceutical companies seek to create more effective and targeted therapies. The market's growth is supported by the increasing investment in personalized medicine initiatives, which is expected to further propel the demand for immortalized cell lines in the coming years. As a result, the industry is poised for substantial growth as it aligns with evolving healthcare paradigms.

    Regulatory Support for Cell Line Research

    Regulatory bodies are increasingly recognizing the importance of immortalized cell lines in research and development, providing a favorable environment for the Global Immortalized Cell Line Market Industry. Guidelines and frameworks established by organizations such as the FDA and EMA facilitate the use of these cell lines in drug development and testing. This regulatory support not only ensures the safety and efficacy of biopharmaceutical products but also encourages investment in cell line research. As regulations evolve to accommodate advancements in cell line technology, the market is likely to experience sustained growth, further solidifying the role of immortalized cell lines in the biopharmaceutical landscape.

    Market Segment Insights

    Immortalized Cell Line Method Insights

    Based on the method, the global market has been segmented into virus induction, hTERT expression, inactivation of tumor suppression genes, and others. The virus induction segment is further divided into EBV genes, SV40 T antigen, HPV-16 E6/6 gene, and others. The hTERT expression segment is sub-segmented into P53 and Myc T58A.

    The immortalized cell line market, based on application, is segmented into diagnostics, drug discovery, vaccine production, 

    and regenerative medicine, and others.

    Immortalized Cell Line End User Insights

    Based on end user, the global market is segmented into pharmaceutical and biopharmaceutical companies, Contract Research Organizations (CROs), and research laboratories. The pharmaceutical and biopharmaceutical companies segment accounted for a market value of USD 1,323.79 million in 2017.  

    Some of the key strategies followed by the players operating in the immortalized cell line market are innovation, product development, acquisition, and expansion.

    Get more detailed insights about Immortalized Cell Line Market Research Report - Global Forecast till 2032

    Key Companies in the Immortalized Cell Line Market market include

    Industry Developments

    In January 2024,

    Thermo Fisher Scientific Launched new Gibco™ Advanced DMEM/F12 media optimized for immortalized cell lines, claiming improved growth and performance.

    In September2023,

    Lonza Group AG Announced partnership with CStone Pharmaceuticals to optimize and manufacture immortalized cell lines for CAR-T cell therapy development.

    Future Outlook

    Immortalized Cell Line Market Future Outlook

    The Immortalized Cell Line Market is projected to grow at a 6.67% CAGR from 2024 to 2035, driven by advancements in biotechnology, increasing demand for drug discovery, and personalized medicine.

    New opportunities lie in:

    • Invest in developing novel immortalized cell lines for specific therapeutic applications.
    • Leverage automation technologies to enhance production efficiency and reduce costs.
    • Expand into emerging markets with tailored solutions for local research needs.

    By 2035, the Immortalized Cell Line Market is expected to achieve substantial growth, reflecting its critical role in biomedical research.

    Market Segmentation

    Immortalized Cell Line Method Outlook

    • Virus Induction
    • EBV genes
    • SV40 T antigen
    • HPV-16 E6/6 gene
    • Others 
    • HTERT Expression
    • P53
    • Myc T58A
    • Inactivation of Tumour Suppression Genes
    • Others

    Immortalized Cell Line End User Outlook

    • Pharmaceutical and Biopharmaceutical Companies
    • Contract Research Organizations
    • Research Laboratories

    Immortalized Cell Line Regional Outlook

    • Americas
    • North America
    • US
    • Canada
    • South America
    • Europe
    • Western Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Rest of Western Europe
    • Eastern Europe
    • Asia-Pacific
    • China
    • Japan
    • India
    • South Korea
    • Rest of Asia-Pacific
    • Middle East & Africa
    • Middle East
    • Africa
    • Research and development (R&D) companies
    • Government research institutes
    • Academic institutes and universities

    Immortalized Cell Line Application Outlook

    • Diagnostics
    • Drug Discovery
    • Vaccine Production
    • Tissue Engineering and Regenerative Medicines
    • Others

    Report Scope

    Attribute/Metric Details
      Market Size 2032   USD 7.56 Billion
      CAGR   6.67% (2024-2032)
      Base Year   2023
      Forecast Period   2024-2032
      Historical Data   2020
      Forecast Units   Value (USD Billion)
      Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
      Segments Covered   Method, Application, End User and Region
      Geographies Covered   North America, Europe, Asia-Pacific, and Rest of the World (RoW)
      Key Vendors  Virus Induction, EBV genes, SV40 T antigen, HPV-16 E6/6 gene, HTERT Expression, Myc T58A, Inactivation of Tumour Suppression Genes
      Key Market Opportunities   Increasing demand for organ donation due to scarcity in the availability of organs
      Key Market Drivers   Increasing government support, well-developed technology

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What will be the value of the Immortalized Cell Line Market during the forecast period?

    Immortalized Cell Line Market is predicted to touch USD 7.56 Billion by 2032.

    At what CAGR is the Immortalized Cell Line Market projected to grow during the forecast period?

    Immortalized Cell Line Market is projected to grow at a 6.67% CAGR between 2024-2032.

    Which region is projected to dominate the Immortalized Cell Line Market?

    North America is projected to dominate the Immortalized Cell Line Market.

    Which end user segment will dominate the Immortalized Cell Line Market?

    Pharmaceutical & biopharmaceutical companies will dominate the Immortalized Cell Line Market.

    What are the key factors boosting the Immortalized Cell Line Market growth?

    Increasing prevalence of cancer, growing need for organ transplantation, and rising application in hospitals, pharmaceutical & biotech companies are boosting market growth.

    Immortalized Cell Line Market Research Report - Global Forecast till 2032 Infographic
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