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    Geographic Atrophy GA Market

    ID: MRFR/HC/9297-HCR
    120 Pages
    Kinjoll Dey
    October 2025

    Geographic Atrophy (GA) Market Research Report Information By Age Group (Above 60 Years and Above 75 Years), By Diagnosis (Fundus Autofluorescence (FAF), Optical Coherence Tomography Angiography (OCT-A), and Multifocal Electroretinography (MfERG)), By Therapeutic Agents Clinical Phase (Late-Stage (Phase III), Phase II, Phase I, and Pre-Clinical Stage & Discovery Candidates) and Region (North America, Europe, Asia-Pacific, and Rest of the World)—Forecast till 2035

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    Geographic Atrophy GA Market Infographic
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    Geographic Atrophy GA Market Summary

    As per MRFR analysis, the Geographic Atrophy (GA) Market. Size was estimated at 23.19 USD Billion in 2024. The Geographic Atrophy industry is projected to grow from 24.93 USD Billion in 2025 to 51.39 USD Billion by 2035, exhibiting a compound annual growth rate (CAGR) of 7.5 during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The Geographic Atrophy market is poised for substantial growth driven by innovative therapies and increasing awareness.

    • The North American market remains the largest, fueled by advanced healthcare infrastructure and high patient awareness.
    • The Asia-Pacific region is emerging as the fastest-growing market, likely due to increasing healthcare investments and a rising aging population.
    • The segment of patients above 75 years constitutes the largest demographic, whereas those above 60 years are experiencing the fastest growth.
    • Key market drivers include the aging population and advancements in diagnostic technologies, which are propelling research and development efforts.

    Market Size & Forecast

    2024 Market Size 23.19 (USD Billion)
    2035 Market Size 51.39 (USD Billion)
    CAGR (2025 - 2035) 7.5%

    Major Players

    Novartis (CH), Regeneron Pharmaceuticals (US), Roche (CH), Bayer (DE), Apellis Pharmaceuticals (US), Alcon (CH), Santen Pharmaceutical (JP), Zeiss (DE), Horizon Therapeutics (IE)

    Geographic Atrophy GA Market Trends

    The Geographic Atrophy (GA) Market is currently experiencing a notable evolution, driven by advancements in research and development, as well as an increasing understanding of the disease's underlying mechanisms. This condition, characterized by the progressive degeneration of retinal cells, poses significant challenges for patients and healthcare providers alike. As the global population ages, the prevalence of GA is likely to rise, prompting a surge in demand for effective treatment options. Pharmaceutical companies are actively exploring innovative therapies, including gene therapy and novel drug formulations, which may offer hope for improved patient outcomes. Furthermore, collaborations between academic institutions and industry stakeholders appear to be fostering a conducive environment for breakthroughs in GA management. In addition to therapeutic advancements, the Geographic Atrophy (GA) Market is witnessing a shift in patient awareness and education. Increased access to information through digital platforms is empowering patients to seek timely diagnosis and treatment. This trend may lead to earlier intervention, potentially slowing disease progression. Moreover, healthcare systems are adapting to accommodate the growing need for specialized care in ophthalmology, which could enhance the overall treatment landscape. As the market continues to evolve, stakeholders must remain vigilant in addressing the multifaceted challenges posed by GA, ensuring that innovations translate into tangible benefits for patients and healthcare providers alike.

    Emergence of Novel Therapeutics

    The Geographic Atrophy (GA) Market is witnessing a surge in the development of innovative therapeutic options. Researchers are focusing on gene therapies and biologics that target the underlying causes of the disease. These advancements may provide new avenues for treatment, potentially altering the disease's trajectory and improving patient quality of life.

    Increased Patient Awareness

    There is a growing trend in patient awareness regarding Geographic Atrophy (GA). Enhanced access to information through various channels is encouraging individuals to seek early diagnosis and treatment. This shift may lead to improved management of the condition, as patients become more proactive in their healthcare decisions.

    Collaborative Research Initiatives

    Collaborations between academic institutions and pharmaceutical companies are becoming more prevalent in the Geographic Atrophy (GA) Market. These partnerships aim to accelerate research and development efforts, fostering innovation in treatment approaches. Such initiatives may enhance the understanding of GA and lead to the discovery of effective therapies.

    The increasing prevalence of geographic atrophy among the aging population underscores the urgent need for innovative therapeutic strategies and enhanced healthcare access to address this debilitating condition.

    National Eye Institute, National Institutes of Health

    Geographic Atrophy GA Market Drivers

    Rising Healthcare Expenditure

    Rising healthcare expenditure is influencing the Geographic Atrophy (GA) Market significantly. As countries allocate more resources to healthcare, there is an increased focus on managing chronic conditions, including geographic atrophy. This trend is particularly evident in regions where healthcare systems are evolving to provide better access to treatments. According to recent data, healthcare spending is projected to grow at an annual rate of 5% over the next decade. This increase in expenditure is likely to facilitate the adoption of advanced therapies and diagnostic tools, thereby propelling the Geographic Atrophy (GA) Market forward. Enhanced funding for healthcare initiatives may also lead to improved patient education and awareness, further driving market growth.

    Emergence of Telemedicine Solutions

    The emergence of telemedicine solutions is reshaping the Geographic Atrophy (GA) Market. With the increasing acceptance of remote healthcare services, patients can now access consultations and follow-up care from the comfort of their homes. This trend is particularly beneficial for individuals with geographic atrophy, who may face mobility challenges. Telemedicine not only enhances patient convenience but also allows for continuous monitoring and management of the condition. The market for telehealth services is expected to expand, with projections indicating a growth rate of over 20% annually. As telemedicine becomes more integrated into standard care practices, the Geographic Atrophy (GA) Market is likely to benefit from improved patient engagement and adherence to treatment regimens.

    Aging Population and Rising Incidence

    The aging population is a primary driver of the Geographic Atrophy (GA) Market. As individuals age, the risk of developing age-related macular degeneration, which includes geographic atrophy, increases significantly. It is estimated that by 2030, the number of people aged 65 and older will reach approximately 1.5 billion, leading to a corresponding rise in GA cases. This demographic shift is likely to create a substantial demand for effective treatments and management strategies within the Geographic Atrophy (GA) Market. Furthermore, the increasing prevalence of chronic diseases associated with aging may exacerbate the incidence of GA, thereby driving market growth as healthcare systems seek to address these challenges.

    Advancements in Diagnostic Technologies

    Technological advancements in diagnostic tools are transforming the Geographic Atrophy (GA) Market. Enhanced imaging techniques, such as optical coherence tomography (OCT) and fundus autofluorescence, allow for earlier and more accurate detection of geographic atrophy. These innovations not only improve patient outcomes but also facilitate the development of targeted therapies. The market for diagnostic devices is projected to grow, with estimates suggesting a compound annual growth rate of over 10% in the coming years. As healthcare providers increasingly adopt these advanced technologies, the Geographic Atrophy (GA) Market is likely to experience a surge in demand for both diagnostic and therapeutic solutions.

    Growing Investment in Research and Development

    Investment in research and development (R&D) is a crucial driver for the Geographic Atrophy (GA) Market. Pharmaceutical companies and biotech firms are increasingly allocating resources to discover and develop novel therapies for GA. In recent years, funding for GA-related research has seen a notable increase, with several clinical trials underway to evaluate new treatment modalities. This influx of investment is expected to yield innovative solutions that address unmet medical needs, thereby expanding the market. The potential for breakthrough therapies not only enhances the prospects for patients but also stimulates growth within the Geographic Atrophy (GA) Market, as successful products can lead to substantial revenue generation.

    Market Segment Insights

    By Age Group: Above 75 Years (Largest) vs. Above 60 Years (Fastest-Growing)

    In the Geographic Atrophy (GA) market, the age group of above 75 years holds the largest share, reflecting the increased prevalence of this ocular condition amongst the elderly population. As individuals age, the risk of age-related macular degeneration and resulting geographic atrophy rises, making this demographic significantly impacted. Conversely, the above 60 years segment is identified as the fastest-growing group, as awareness of GA is increasing, leading to more diagnoses and treatments sought by slightly younger seniors who are beginning to experience vision issues.

    Above 75 Years (Dominant) vs. Above 60 Years (Emerging)

    The demographic of patients above 75 years is characterized by a higher incidence of geographic atrophy due to age-related declines in ocular health, making them a dominant segment in the market. This group often has comorbidities that exacerbate GA, resulting in a strong demand for tailored interventions. Meanwhile, the above 60 years cohort represents an emerging market segment, characterized by increasing health literacy and proactive health management among seniors. This segment is likely to witness growth due to shifting demographics and the increasing availability of GA treatments, positioning it as an important focus for market players.

    By Diagnosis: Fundus Autofluorescence (FAF) (Largest) vs. Optical Coherence Tomography Angiography (OCT-A) (Fastest-Growing)

    The Geographic Atrophy (GA) Market has witnessed a notable distribution in its diagnostic segment, with Fundus Autofluorescence (FAF) leading as the largest share holder. It dominates the market due to its effectiveness in visualizing retinal structures and metabolic changes. On the other hand, Optical Coherence Tomography Angiography (OCT-A) is establishing a substantial foothold, recognized for its rapid growth owing to advancements in imaging techniques. Multifocal Electroretinography (MfERG), while essential for assessing retinal function, occupies a smaller share in comparison to the more widely adopted FAF and OCT-A diagnostics. Growth trends in the GA diagnostic market reflect a shift towards novel imaging technologies that offer higher precision and user-friendliness. OCT-A is emerging as a key player due to its non-invasive nature, making it a preferred choice for clinicians. The integration of artificial intelligence and technological innovations to enhance image quality and analysis is also propelling its adoption. Meanwhile, FAF continues to thrive due to its established credibility in detecting early signals of GA, ensuring its persistent relevance in the market.

    Fundus Autofluorescence (FAF) (Dominant) vs. Multifocal Electroretinography (MfERG) (Emerging)

    In the Geographic Atrophy (GA) Market, Fundus Autofluorescence (FAF) stands as the dominant diagnostic tool, primarily due to its ability to provide clear visualizations of lipofuscin accumulation in the retina, which is pivotal for early detection. FAF's non-invasive nature and established clinical utility make it a staple among ophthalmologists. On the other hand, Multifocal Electroretinography (MfERG) is categorized as an emerging diagnostic modality, offering detailed insights into the functional status of the retina across multiple loci. Although still gaining traction, MfERG is recognized for its potential in assessing ganglion cell function and retinal integrity, especially in earlier stages of GA, thus positioning it as a valuable complement in comprehensive diagnostic strategies.

    By Therapeutic Agents Clinical Phase: Late-Stage (Largest) vs. Phase II (Fastest-Growing)

    In the Geographic Atrophy (GA) Market, the segmentation by therapeutic agents clinical phase reveals a dynamic landscape where the Late-Stage (Phase III) sector holds the largest share. This segment's prominence is attributed to advanced clinical trials and a robust pipeline of treatments nearing approval, reinforcing investor confidence. Meanwhile, Phase II shows significant growth potential, characterized by increased investments and successful initial results from clinical trials, signaling a progressive shift in the treatment paradigm for GA.

    Therapeutic Agents: Late-Stage (Dominant) vs. Phase II (Emerging)

    The Late-Stage (Phase III) segment stands out as the dominant force within the GA market, showcasing numerous candidates with a solid clinical foundation leading to potential market entry. These agents typically undergo rigorous testing, ensuring a comprehensive understanding of efficacy and safety, which boosts confidence among practitioners. Conversely, Phase II represents an emerging segment buoyed by promising clinical outcomes, attracting attention from pharmaceutical companies seeking innovative therapies. This phase is marked by vital studies that refine dosages and indications, providing essential data that could influence future treatment protocols and drive market expansion.

    Get more detailed insights about Geographic Atrophy GA Market

    Regional Insights

    By Region, the study segments the market into North America, Europe, Asia-Pacific, and the Rest of the World. The North America geographic atrophy (GA) market is expected to account for USD XX billion in 2021 and is expected to exhibit an XX% CAGR during the study period. This is attributed to the rising investment in the healthcare industry and the presence of major key players in the region such as Apellis Pharmaceuticals, Inc. (US), Iveric Bio (US), Alkeus Pharmaceuticals Inc. (US), and others.

    Moreover, the rising number of patients suffering from geographic atrophy and growing government initiatives related to geographic atrophy in the region further fuel the growth of the market.

    Further, the major countries studied are the U.S., Canada, Germany, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 3 GEOGRAPHIC ATROPHY (GA) MARKET SHARE BY REGION 2021 (%)GEOGRAPHIC ATROPHY (GA) MARKET SHARE BY REGION 2021

    Source Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Europe geographic atrophy (GA) market is expected to account for the second-largest market share due to the rising older population, increasing demand for technologically innovative treatment, and growing R&D investment by the biopharmaceutical industry. Further, the Germany geographic atrophy (GA) market is expected to hold third place for the market share, and the UK geographic atrophy (GA) market is expected to fastest-growing market, and which is in the 4th place in the European region. Furthermore, France geographic atrophy (GA) market will hold the 5th place for the market share.

    The Asia-Pacific geographic atrophy (GA) market is expected to grow at a CAGR of XX% from 2022 to 2030. This is due to the developing healthcare infrastructure, the establishment of research organizations, and the rising prevalence of AMD disorders among the elderly population. Moreover, China geographic atrophy (GA) market is expected to hold the largest market share, and the India geographic atrophy (GA) market is expected fastest-growing market in the Asia-Pacific region.

    For instance, According to World Health Organization (WHO), 90% of the total visually impaired people live in developing countries such as China, India, and others, to become the leader in the geographic atrophy (GA) market.

    The Rest of the World includes the Middle East, Africa, and Latin America. Government initiatives to increase medical expenditure and increase healthcare infrastructure in the region contribute to the growth of the geographic atrophy (GA) market.

    Key Players and Competitive Insights

    The presence of major market players in the Geographic Atrophy (GA) market is characterized by the presence of many international, regional, and local players. growing geriatric population and increasing prevalence of geographic atrophy, and increased healthcare expenditure globally. In addition, the companies are investing in R&D activities to expand their product portfolio for GA, which further drives the growth of the geographic atrophy market. Moreover, the vendors compete based on cost, product quality, reliability, and aftermarket services and try to be the first to bring a treatment for the public.

    It is crucial for the players to offer cost-efficient and high-quality products for geographic atrophy to succeed in an intensely competitive market environment.

    One of the primary business strategies adopted by manufacturers in the geographic atrophy (GA) industry to benefit clients and expand the geographic atrophy (GA) market sector is to manufacture locally to reduce operating costs.

    Genentech, Inc. is a biotechnology company dedicated to discovering and developing medicines for patients suffering from serious and potentially fatal illnesses. Genentech is a wholly owned subsidiary of Roche Holding Ltd. Genentech conducts research, develops, manufactures, and distributes human pharmaceuticals to address important medical needs. The company produces animals from gene cells that would not typically be produced by the cell, and it has six offices across the U. S.

    For instance, in December 2022, Genentech (US) Launches Phase 2a Study of RG6501 (OpRegen) in Patients with Geographic Atrophy. a phase 2a, multicenter, open-label, single-arm clinical study of RG6501 (OpRegen), a retinal pigment epithelial cell therapy. The goal of the trial is to assess the safety and efficacy of OpRegen in up to 60 patients with geographic atrophy (GA) brought on by age-related macular degeneration. The study will examine the best subretinal surgical delivery method.

    Also, Iveric Bio (US) is a biopharmaceutical company dedicated to the research and creation of innovative therapies for retinal conditions with unmet medical needs. The company is developing both therapeutic product candidates for age-related retinal diseases and gene therapy product candidates for orphan inherited retinal diseases or IRDs. In June 2022, Iveric Bio's(US) positive topline data from Zimura GATHER2 Phase 3 clinical trial in geographic atrophy.

    Key Companies in the Geographic Atrophy GA Market market include

    Industry Developments

    December 2022 Genentech (US) Launched Phase 2a Study of RG6501 (OpRegen) in Patients with Geographic Atrophy. a phase 2a, multicenter, open-label, single-arm clinical study of RG6501 (OpRegen), a retinal pigment epithelial cell therapy. The goal of the trial is to assess the safety and efficacy of OpRegen in up to 60 patients with geographic atrophy (GA) brought on by age-related macular degeneration. The study will examine the best subretinal surgical delivery method

    November 2022 The FDA has approved Apellis Pharmaceuticals Inc’s New Drug Application (NDA) for intravitreal pegcetacoplan for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)

    June 2019 Allegro Ophthalmics (US) Announces Positive topline vision results of phase 2 study evaluating risuteganib in patients with intermediate dry age-related macular degeneration.

    September 2021 The U.S. Food and Drug Administration (FDA) has approved the Stealth BioTherapeutics's (Cayman Islands) fast track classification for the treatment of dry geographic atrophy-associated age-related macular degeneration (AMD).

    July 2021 Alkeus Pharmaceuticals'(US) C20-D3-Vitamin A (USALK-001) has been approved by the FDA as a revolutionary therapy for the treatment of Stargardt disease.

    Geographic Atrophy (GA) Market Segmentation

    Geographic Atrophy (GA) Age Group Outlook

    Above 60 Years

    Above 75 Years

    Geographic Atrophy (GA) Diagnosis Outlook

    Fundus Autofluorescence (FAF)

    Optical Coherence Tomography Angiography (OCT-A)

    Multifocal Electroretinography (MfERG)

    Geographic Atrophy (GA) Therapeutic Agents Clinical Phase Outlook

    Late-Stage (Phase III)

    Phase II

    Phase I

    Pre-Clinical Stage & Discovery Candidates

    Geographic Atrophy (GA) Regional Outlook

    • North America
      • US
      • Canada
    • Europe
      • Germany
      • France
      • UK
      • Italy
      • Spain
      • Rest of Europe
    • Asia-Pacific
      • China
      • Japan
      • India
      • Australia
      • South Korea
      • Australia
      • Rest of Asia-Pacific
    • Rest of the World
      • Middle East
      • Africa
      • Latin America

    Future Outlook

    Geographic Atrophy GA Market Future Outlook

    The Geographic Atrophy market is projected to grow at a 7.5% CAGR from 2024 to 2035, driven by advancements in treatment options and increasing patient awareness.

    New opportunities lie in:

    • Development of targeted gene therapies for GA treatment.
    • Expansion of telemedicine platforms for remote patient monitoring.
    • Investment in AI-driven diagnostic tools for early detection.

    By 2035, the Geographic Atrophy market is expected to be robust, driven by innovative therapies and enhanced patient engagement.

    Market Segmentation

    Geographic Atrophy GA Market Age Group Outlook

    • Above 60 Years
    • Above 75 Years

    Geographic Atrophy GA Market Diagnosis Outlook

    • Fundus Autofluorescence (FAF)
    • Optical Coherence Tomography Angiography (OCT-A)
    • Multifocal Electroretinography (MfERG)

    Geographic Atrophy GA Market Therapeutic Agents Clinical Phase Outlook

    • Late-Stage (Phase III)
    • Phase II
    • Phase I
    • Pre-Clinical Stage & Discovery Candidates

    Report Scope

    MARKET SIZE 202423.19(USD Billion)
    MARKET SIZE 202524.93(USD Billion)
    MARKET SIZE 203551.39(USD Billion)
    COMPOUND ANNUAL GROWTH RATE (CAGR)7.5% (2024 - 2035)
    REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR2024
    Market Forecast Period2025 - 2035
    Historical Data2019 - 2024
    Market Forecast UnitsUSD Billion
    Key Companies ProfiledMarket analysis in progress
    Segments CoveredMarket segmentation analysis in progress
    Key Market OpportunitiesAdvancements in gene therapy and regenerative medicine present new avenues in the Geographic Atrophy (GA) Market.
    Key Market DynamicsRising demand for innovative therapies drives competitive dynamics in the Geographic Atrophy market.
    Countries CoveredNorth America, Europe, APAC, South America, MEA

    Market Highlights

    Author
    Kinjoll Dey
    Research Analyst Level I

    He is an extremely curious individual currently working in Healthcare and Medical Devices Domain. Kinjoll is comfortably versed in data centric research backed by healthcare educational background. He leverages extensive data mining and analytics tools such as Primary and Secondary Research, Statistical Analysis, Machine Learning, Data Modelling. His key role also involves Technical Sales Support, Client Interaction and Project management within the Healthcare team. Lastly, he showcases extensive affinity towards learning new skills and remain fascinated in implementing them.

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    FAQs

    How much is the geographic atrophy (GA) market?

    The geographic atrophy (GA) market is anticipated to reach USD 36.1 billion at a CAGR of 7.5% during the forecast period of 2023 to 2032.

    What is the growth rate of the geographic atrophy (GA) market?

    The geographic atrophy (GA) market is expected to register a CAGR of 7.5% during the forecast period of 2023 to 2032.

    Which region held the largest market share in the Geographic Atrophy (GA) Market?

    The North America geographic atrophy (GA) market.

    Who are the key players in the geographic atrophy (GA) Market?

    Apellis Pharmaceuticals, Inc. (US), Iveric Bio (US), Alkeus Pharmaceuticals, Inc. (US), Hemera Biosciences LLC (US), Allegro Ophthalmics, LLC (US), Stealth BioTherapeutics (Cayman Islands), Gyroscope Therapeutics Limited (UK), F. Hoffmann-La Roche AG (Switzerland), Genentech, Inc. (US), and Gensight Biologics SA (France).

    Which type diagnosis the geographic atrophy (GA) market?

    The optical coherence tomography angiography (OCT-A) segment held the majority share in 2021

    Which stage had the largest market share in the Geographic Atrophy (GA) Market?

    The late-stage (Phase III) segment dominated the market in 2021 and is projected to be the faster-growing segment during the forecast period, 2023-2032.

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