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Cryo Electron Microscopy Market Research Report By Product Type (Transmission Electron Microscopes (TEM), Scanning Electron Microscopes (SEM)), By Application (Structural Biology, Materials Science, Imaging, Pharmaceutical Research), By Detector (Direct Electron Detectors, Indirect Electron Detectors), By End User (Research Academic Institutes, Pharmaceutical Companies, Biotechnology Companies) and By Region (North America, Europe, South America, Asia Pacific, Middle East and Africa)- Forecast to 2032


ID: MRFR/HC/9837-HCR | 111 Pages | Author: Rahul Gotadki| October 2024

Cryo Electron Microscopy Market Overview


The cryo electron microscopy market size was estimated at 2.04 (USD Billion) in 2022. The Global cryo electron microscopy industry is expected to grow from 2.31(USD Billion) in 2023 to 7.1 (USD Billion) by 2032. The cryo electron microscopy market CAGR (growth rate) is expected to be around 13.3% during the forecast period (2024-2032).


Key Cryo Electron Microscopy Market Trends Highlighted


Key market drivers for cryo electron microscopy include the increasing prevalence of complex diseases, advancements in sample preparation techniques, and the growing need for high-resolution imaging in pharmaceutical research and development. Recent trends indicate a shift towards automated systems, improved resolution capabilities, and the integration of artificial intelligence for data analysis.


Opportunities to be explored in the cryo electron microscopy market include the development of portable devices for point-of-care diagnostics, the expansion into emerging markets, and the adoption of cloud-based data management solutions.


Cryo Electron Microscopy Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Cryo Electron Microscopy Market Drivers


Advancements in Technology


The cryo electron microscopy market is primarily driven by rapid advancements in technology. The development of new and innovative instruments has made it possible to obtain high-resolution images of biological molecules, which has opened up new avenues for research. For example, the development of direct electron detectors has significantly improved the sensitivity and resolution of cryo-EM, making it possible to visualize even smaller structures.


Additionally, the development of new software has made it easier to process and analyze cryo-EM data, which has made the technique more accessible to a wider range of researchers.  The increasing use of cryo-EM in structural biology is also being driven by the development of new methods for sample preparation. These methods have made it possible to image a wider range of biological molecules, including membrane proteins and large protein complexes.


As a result, cryo-EM is now being used to study a wider range of biological processes, including protein folding, protein-protein interactions, and virus assembly.  The advancements in technology and the increasing use of cryo-EM in structural biology are expected to continue to drive the growth of the cryo electron microscopy market in the coming years.


Growing Demand for Cryo-EM in Drug Discovery


Another major factor driving the growth of the cryo electron microscopy market is the growing demand for this technique in drug discovery. Cryo-EM can be used to determine the structure of proteins and other biological molecules, which can help researchers to discover new drug targets and develop new drugs. For example, cryo-EM has been used to determine the structure of the SARS-CoV-2 virus, which has facilitated the development of new vaccines and drugs.


Government Funding for Cryo-EM Research


Government funding is further fuelling the growth of the cryo electron microscopy market. Around the world, governments are investing in cryo EM research and in specialized centers in order to boost the use of cryo electron microscopes by providing easy access to the appropriate infrastructure and innovation.


For example, the National Institutes of Health in the United States has heavily invested in cryo electron microscopy research, with the United States now considered to be one of the countries spearheading the use of the technique in research.


Cryo Electron Microscopy Market Segment Insights


Cryo Electron Microscopy Market Product Type Insights


The cryo electron microscopy market is classified by product type into Transmission Electron Microscopes (TEM) and Scanning Electron Microscopes (SEM). In 2023, the TEM segment acquired the largest revenue share and is expected to remain dominant throughout the forecast period.


The growth of this segment is mainly due to increasing demand for high-resolution imaging of biological samples. The SEM segment is anticipated to grow at a significant rate over the forecast period. The growth of the market is attributed to the increasing demand for high-resolution imaging applications in the life sciences industry, demanding for SEM in different industrial sectors, and investments made on R activities.

The cryo electron microscopy market is a highly competitive market. Several key players are operating in the market that includes Thermo Fisher Scientific, FEI Company, Hitachi High-Technologies Corporation, JEOL Ltd., and Bruker Corporation.


These key players invest huge amounts on research activities to produce innovative and new products. Moreover, with the growth in demand for products, the market is witnessing the entry of new participants with their new and innovative products at low prices. This, in turn, will increase market competition resulting in decreasing prices. Hence, the cryo electron microscopy market is expected to grow in the upcoming years.


Cryo Electron Microscopy Market Product Type


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Cryo Electron Microscopy Market Application Insights


The cryo electron microscopy market segmentation by Application is expected to reach USD 2.01 billion in 2024 and is projected to grow at a CAGR of 12.8% from 2024 to 2032. The growth of the market is attributed to the increasing adoption of cryo-electron microscopy in various fields of research, including structural biology, materials science, imaging, and pharmaceutical research.


In structural biology, cryo-electron microscopy is used to determine the structure of proteins and other biological molecules. This information is essential for understanding the function of proteins and for developing new drugs and therapies.


In materials science, cryo-electron microscopy is used to study the structure of materials at the atomic level. This information can be used to develop new materials with improved properties. In imaging, cryo-electron microscopy is used to create high-resolution images of cells and tissues.


This information can be used for diagnostic purposes and for studying the development of diseases. In pharmaceutical research, cryo-electron microscopy is used to study the structure of drug targets. This information can be used to design new drugs that are more effective and have fewer side effects.


Cryo Electron Microscopy Market Detector Insights


The detector segment is further divided into direct electron detectors and indirect electron detectors. Direct Electron Detectors are expected to account for a significant market share, owing to their ability to capture images of biological samples at high resolution and with minimal noise.


Indirect electron detectors are expected to grow at a faster CAGR during the forecast period, due to their lower cost and smaller size. Key players in the detector segment include Thermo Fisher Scientific, FEI Company, and JEOL Ltd.


Cryo Electron Microscopy Market End User Insights


The cryo electron microscopy market is segmented into end users such as research and academic institutes, pharmaceutical companies, and biotechnology companies. Among these, research and academic institutes are projected to hold a significant market share in the coming years.


This is mainly due to the increasing adoption of cryo-EM in academic research, particularly in structural biology and drug discovery. Cryo-EM offers researchers a powerful tool to study the structure and dynamics of biological molecules at near-atomic resolution, leading to advancements in understanding disease mechanisms and developing new therapies.


Pharmaceutical and biotechnology companies are also investing heavily in cryo-EM to enhance their drug discovery and development process. Cryo-EM enables them to visualize the structure of proteins and other biological molecules, helping them identify potential targets and optimize drug design. As a result, the cryo electron microscopy market is expected to witness substantial growth in the coming years, driven by the expanding applications in research and drug development.


Cryo Electron Microscopy Market Regional Insights


The cryo electron microscopy market revenue is expected to reach 3.24 Billion USD in 2024, expanding at a CAGR of 13.3% from 2023 to 2032. Regionally, North America held the largest market share in 2023, accounting for 38.5% of the market.


This dominance is attributed to the presence of major market players, high research and development spending, and increasing adoption of cryo-EM technology in pharmaceutical and biotechnology industries.


Additionally, Europe and APAC are anticipated to exhibit significant growth prospects due to rising healthcare expenditure, government initiatives, and a growing number of research institutions. South America and MEA are expected to witness a steady growth rate, driven by increasing investments in healthcare infrastructure and rising awareness about cryo-EM applications.


Cryo Electron Microscopy Market Regional


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Cryo Electron Microscopy Market Key Players And Competitive Insights


The cryo electron microscopy market’s major players are working in a concerted manner to come up with efficient new products and also adopting forward-looking highly innovative solutions to ensure a firm presence in this cutthroat sector.


Currently, companies leading in the cryo electron microscopy market are focusing on broadening their consumer base through forming alliances and acquiring new business. Factors that may stimulate the market’s expansion include the increasing demand for high-resolution imaging across the major scientific sectors, regular governmental funding for research and advancements, and ongoing market investments.


Existing and even new market participants rely on these peripherals to distinguish their products from those of competitors and to concentrate purely on enhancing the product as new investments flow into the cryo electron microscopy market. The competitive landscape is projected to become even more abrasive as current participants expand their operations within the industry through continuous research and innovations.


The market’s dominant companies include Thermo Fisher Scientific, which provides a broad choice of high-tech cryo-electron microscopes and necessary peripherals. This business has built a worldwide presence with a distribution network that has successfully satisfied an increasing consumer base. The company strives to safeguard its market influence by concentrating on R and constantly launching new technologies.


Consequently, many academic institutions and even well-recognized pharmaceutical companies favor this corporation. JEOL is another well-known player in the cryo electron microscopy market. This company has a long legacy of supplying cutting-edge technologies to the electron microscopy world. The business has established itself by giving customers extremely innovative cryo-electron microscopes and consumers a high-quality level of dependability.


Key Companies in the Cryo Electron Microscopy Market Include



  • Thermo Fisher Scientific

  • Bruker

  • Hitachi

  • Nikon

  • Oxford Instruments

  • Rigaku

  • Renishaw

  • Quorum Technologies

  • ZEISS

  • Protochips

  • Carl Zeiss

  • JEOL


Cryo Electron Microscopy Market Developments


The cryo electron microscopy market is anticipated to reach USD 7.1 billion by 2032, exhibiting a CAGR of 13.3% during the forecast period (2024-2032). Advancements in technology, such as the development of direct electron detectors and image processing software, have significantly contributed to the market growth.


Additionally, the rising prevalence of chronic diseases and the increasing demand for personalized medicine are driving market expansion. Key players in the market include Thermo Fisher Scientific, FEI Company, and JEOL Ltd. Recent developments include the launch of the Thermo Scientific Krios G4 Cryo-TEM by Thermo Fisher Scientific and the introduction of the JEM-GrandIS Cryo-EM by JEOL Ltd. These advancements aim to enhance the resolution and efficiency of cryo-EM techniques.


Cryo Electron Microscopy Market Segmentation Insights

Cryo Electron Microscopy Market Product Type Outlook



  • Transmission Electron Microscopes (TEM)

  • Scanning Electron Microscopes (SEM)


Cryo Electron Microscopy Market Application Outlook



  • Structural Biology

  • Materials Science

  • Imaging

  • Pharmaceutical Research


Cryo Electron Microscopy Market Detector Outlook



  • Direct Electron Detectors

  • Indirect Electron Detectors


Cryo Electron Microscopy Market End User Outlook



  • Research & Academic Institutes

  • Pharmaceutical Companies

  • Biotechnology Companies


Cryo Electron Microscopy Market Regional Outlook



  • North America

  • Europe

  • South America

  • Asia Pacific

  • Middle East and Africa

Report Attribute/Metric Details
Market Size 2022 2.04 (USD Billion)
Market Size 2023 2.31(USD Billion)
Market Size 2032 7.1(USD Billion)
Compound Annual Growth Rate (CAGR) 13.3% (2024-2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024-2032
Historical Data 2019-2023
Market Forecast Units USD Billion
Key Companies Profiled Thermo Fisher Scientific, Bruker, Hitachi, Nikon, Thermo Fisher Scientific, Oxford Instruments, Rigaku, Renishaw, Quorum Technologies, ZEISS, Protochips, Carl Zeiss, JEOL
Segments Covered Product Type, Application, Detector, End User, Region
Key Market Opportunities 1.       Increased Research and Innovation 2.       Advanced Imaging Techniques 3.       Growing Application in Structural Biology 4.       Rising Demand for High Resolution Images
Key Market Dynamics 1.       Increasing Demand for High Resolution Imaging 2.       Growing Pharmaceutical and Biotechnology Sector 3.       Advancements in Technology 4.       Strategic Collaborations and Partnerships 5.       Expanding Applications in Drug Discovery and Development
Countries Covered North America, Europe, APAC, South America, MEA
 

Frequently Asked Questions (FAQ) :

The cryo electron microscopy market was valued at USD 2.31 billion in 2023.

The cryo electron microscopy market is projected to grow at a CAGR of 13.3% from 2024 to 2032.

North America is expected to hold the largest market share in the cryo electron microscopy market in 2032.

The drug discovery and development segment is expected to hold the largest market share in the cryo electron microscopy market in 2032.

Key competitors in the cryo electron microscopy market include Thermo Fisher Scientific, Hitachi High-Technologies Corporation, and JEOL Ltd.

Key factors driving the growth of the cryo electron microscopy market include increasing adoption of cryo-EM in drug discovery and development, growing demand for high-resolution imaging, and technological advancements.

Challenges faced by the market include high cost of equipment and consumables, lack of skilled professionals, and data interpretation challenges.

Expected trends in the market include increasing adoption of AI and machine learning, development of new sample preparation techniques, and growing demand for cryo-EM in structural biology.

The cryo electron microscopy market is projected to reach USD 7.1 billion by 2032.

Asia Pacific is expected to have the highest growth rate in the cryo electron microscopy market from 2024 to 2032.

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