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    Collagen Hyaluronic Acid Intra Articular Injections Market

    ID: MRFR/HC/57883-CR
    181 Pages
    Rahul Gotadki
    July 2025

    Collagen and Hyaluronic Acid Intra-Articular Injections Market Research Report Information by Product Type (Hyaluronic Acid Injection (Single Injection, Multiple Injection), Collagen Injection, Combination of Hyaluronic Acid and Collagen), by Application (Knee Osteoarthritis, Joint Pain, Veterinary Applications, Post-Operative Recovery, Others), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and Region (North America, Europe, Asia-Pacific, Latin America, Middle East & Africa) - Forecast till 2035

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    Collagen and Hyaluronic Acid Intra-Articular Injections Market Research Report – Forecast Till 2035 Infographic
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    Collagen Hyaluronic Acid Intra Articular Injections Market Summary

    The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market is projected to grow from 3.5 USD Billion in 2024 to 7.2 USD Billion by 2035.

    Key Market Trends & Highlights

    Collagen and Hyaluronic Acid Intra-Articular Injections Key Trends and Highlights

    • The market is expected to witness a compound annual growth rate (CAGR) of 6.78% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 7.2 USD Billion, indicating robust growth.
    • In 2024, the market is valued at 3.5 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of intra-articular injections due to increasing prevalence of joint disorders is a major market driver.

    Market Size & Forecast

    2024 Market Size 3.5 (USD Billion)
    2035 Market Size 7.2 (USD Billion)
    CAGR (2025 - 2035) 6.78%

    Major Players

    Apple Inc (US), Microsoft Corp (US), Amazon.com Inc (US), Alphabet Inc (US), Berkshire Hathaway Inc (US), Tesla Inc (US), Meta Platforms Inc (US), Johnson & Johnson (US), Visa Inc (US), Samsung Electronics Co Ltd (KR)

    Collagen Hyaluronic Acid Intra Articular Injections Market Drivers

    Market Growth Projections

    The Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry is poised for substantial growth, with projections indicating a market size of 3.5 USD Billion in 2024 and an anticipated increase to 7.2 USD Billion by 2035. This growth trajectory suggests a compound annual growth rate of 6.78% from 2025 to 2035, driven by factors such as rising prevalence of joint disorders, advancements in injection techniques, and increasing consumer awareness. The market's expansion reflects a broader trend towards innovative and effective treatment options in the healthcare sector, highlighting the potential for continued investment and development in this area.

    Growing Awareness of Joint Health

    There is a notable increase in awareness regarding joint health and the benefits of collagen and hyaluronic acid injections. Educational campaigns and healthcare initiatives are informing the public about the advantages of these treatments, contributing to the growth of the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry. As individuals become more proactive about their health, they are more likely to seek out these therapies. This heightened awareness is expected to drive market expansion, with projections indicating a market size of 7.2 USD Billion by 2035. The emphasis on preventive care and wellness is likely to further bolster this trend.

    Rising Prevalence of Osteoarthritis

    The increasing incidence of osteoarthritis globally is a primary driver for the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry. As populations age, the demand for effective treatments rises, with osteoarthritis affecting millions worldwide. In 2024, the market is projected to reach 3.5 USD Billion, reflecting the urgent need for innovative therapies. Injections of collagen and hyaluronic acid have shown promise in alleviating joint pain and improving mobility, making them a preferred choice among healthcare providers. This trend is expected to continue, as the aging demographic seeks non-surgical options for managing joint health.

    Advancements in Injection Techniques

    Technological advancements in injection techniques are enhancing the efficacy and safety of collagen and hyaluronic acid intra-articular injections. Innovations such as ultrasound-guided injections and improved formulations are making these procedures more effective, thereby driving the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry. As healthcare providers adopt these advanced techniques, patient outcomes improve, leading to increased patient satisfaction and a higher likelihood of repeat treatments. This trend is expected to contribute to a compound annual growth rate of 6.78% from 2025 to 2035, reflecting the growing confidence in these therapies among both practitioners and patients.

    Expanding Applications Beyond Orthopedics

    The applications of collagen and hyaluronic acid injections are expanding beyond traditional orthopedic uses, which is positively impacting the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry. These injections are now being explored for use in various medical fields, including sports medicine and aesthetic treatments. As research continues to uncover new benefits, the market is likely to see increased demand from diverse sectors. This diversification may contribute to the overall market growth, with projections indicating a size of 3.5 USD Billion in 2024. The potential for broader applications suggests a promising future for these therapies.

    Rising Demand for Minimally Invasive Procedures

    The shift towards minimally invasive procedures is significantly influencing the Global Collagen and Hyaluronic Acid Intra-Articular Injections Market Industry. Patients increasingly prefer treatments that involve less recovery time and lower risks compared to traditional surgical options. Collagen and hyaluronic acid injections offer a viable alternative, providing pain relief and improved joint function without the need for invasive surgery. This trend is likely to accelerate market growth, as more individuals seek these less invasive solutions. The market's projected growth to 7.2 USD Billion by 2035 underscores the increasing acceptance of these therapies in managing joint-related conditions.

    Market Segment Insights

    Collagen and Hyaluronic Acid Intra-Articular Injections

    Based on Product Type, this segment includes Hyaluronic Acid Injection (Single Injection, Multiple Injection), Collagen Injection, Combination of Hyaluronic Acid and Collagen. The Hyaluronic Acid Injection segment dominated the global market in 2024, while it is projected to be the fastest–growing segment during the forecast period. 

    Both single and multiple injection variants are popular for treating joint disorders and enhancing skin volume. This segment is also projected to be the fastest growing during the forecast period due to increasing demand for non-surgical cosmetic procedures, aging populations, and growing awareness of hyaluronic acid’s effectiveness. Technological advancements and improved formulations are further accelerating their adoption across medical and cosmetic fields, boosting market growth in the coming years.

    FIGURE 2: COLLAGEN AND HYALURONIC ACID INTRA-ARTICULAR INJECTIONS MARKET SHARE BY PRODUCT TYPE 2024 AND 2035 (USD BILLION)

    Source: Secondary Research, Primary Research, MRFR Database and Analyst Review

    Collagen and Hyaluronic Acid Intra-Articular Injections

    Based on Application, this segment includes Knee Osteoarthritis, Joint Pain, Veterinary Applications, Post-Operative Recovery, Others. The Knee Osteoarthritis segment dominated the global market in 2024, while it is projected to be the fastest–growing segment during the forecast period. 

    This segment is also projected to be the fastest growing during the forecast period, driven by increasing awareness of early intervention, rising healthcare expenditure, and the growing preference for non-surgical treatments. Additionally, advancements in injection therapies and the growing burden of osteoarthritis worldwide are expected to further propel demand, making this segment a key contributor to overall market expansion in the coming years.

    Collagen and Hyaluronic Acid Intra-Articular Injections

    Based on Distribution Channel, this segment includes Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies. The Hospital Pharmacies segment dominated the global market in 2024, while the Online Pharmacies segment is projected to be the fastest–growing segment during the forecast period. Hospital pharmacies are often the primary source for post-operative and osteoarthritis care, contributing significantly to sales volume. 

    However, the Online Pharmacies segment is projected to be the fastest growing during the forecast period. This growth is driven by increasing internet penetration, rising consumer preference for convenience, and the availability of a wide range of products at competitive prices. In addition, the expansion of telehealth services and improvements in e-commerce platforms have enhanced the accessibility and reliability of online medication purchases. As digital healthcare adoption increases globally, the online channel is expected to witness substantial growth, especially in urban and tech-savvy regions.

    Get more detailed insights about Collagen and Hyaluronic Acid Intra-Articular Injections Market Research Report – Forecast Till 2035

    Regional Insights

    Based on the Region, the global Collagen and Hyaluronic Acid Intra-Articular Injections are segmented into North America, Europe, Asia-Pacific, Latin America and Middle East & Africa. The North America dominated the global market in 2024, while the Asia-Pacific is projected to be the fastest–growing segment during the forecast period. Major demand factors driving the North America market are the rising prevalence of osteoarthritis and joint disorders and growing aging population. 

    The region also benefits from well-established healthcare infrastructure, widespread adoption of advanced medical treatments, and high awareness regarding non-surgical therapeutic options such as intra-articular injections. Additionally, increased healthcare spending and favorable reimbursement policies contribute to market growth in the region. However, the Asia-Pacific region is projected to be the fastest-growing during the forecast period. This growth is driven by a rapidly aging population, rising healthcare expenditure, growing awareness of joint health treatments, and expanding access to healthcare services across emerging economies such as China, India, and Southeast Asian countries.

    FIGURE 3: COLLAGEN AND HYALURONIC ACID INTRA-ARTICULAR INJECTIONS MARKET VALUE BY REGION 2024 AND 2035 (USD BILLION)

    COLLAGEN AND HYALURONIC ACID INTRA-ARTICULAR INJECTIONS MARKET VALUE BY REGION 2024 AND 2035

    Source: Secondary Research, Primary Research, Market Research Future Database, and Analyst Review

    Further, the countries considered in the scope of the Application Tracking System Market are the US, Canada, Germany, UK, France, Russia, Italy, Spain, China, India, Japan, South Korea, Malaysia, Thailand, Indonesia, Brazil, Mexico, Argentina, GCC Countries, South Africa and others.

    Key Players and Competitive Insights

    Many global, regional, and local vendors characterize the Collagen and Hyaluronic Acid Intra-Articular Injections Market. The market is highly competitive, with all the players competing to gain market share. Intense competition, rapid advances in technology, frequent changes in government policies, and environmental regulations are key factors that confront market growth. The vendors compete based on cost, product quality, reliability, and government regulations. Vendors must provide cost-efficient, high-quality products to survive and succeed in an intensely competitive market.

    The major competitors in the market are Seikagaku Corporation, Bioventus, Inc., Anika Therapeutics, Inc., Zimmer Biomet, Sanofi, Teva Pharmaceutical Industries Ltd., Ferring B.V., Dr. Reddy's Laboratories Ltd., Fidia Farmaceutici S.p.A., Semical Biosurgery, Avanos Medical, Inc., Maxigen Biotech Inc. (MBI) are among others. The Collagen and Hyaluronic Acid Intra-Articular Injections Market is a consolidated market due to increasing competition, acquisitions, mergers and other strategic market developments and decisions to improve operational effectiveness.

    Key Companies in the Collagen Hyaluronic Acid Intra Articular Injections Market market include

    Industry Developments

    February 2024: MBI received approval for ArtiAid and ArtiAidPlus Intra-articular Injection for marketing authorization from the Saudi Food and Drug Authority.

    August 2021: Seikagaku Corporation launched HyLink, an intra-articular single injection viscosupplement for the treatment of knee osteoarthritis.

    May 2021: Ono Pharmaceutical Co., Ltd. and Seikagaku Corporation announed that Ono has launched JOYCLU 30mg Intra-articular Injection (generic name: diclofenac etalhyaluronate sodium; “JOYCLU”), a joint function improvement agent, for which Seikagaku received the manufacturing and marketing approval in Japan.

    January 2019: Bioventus, a global leader in orthobiologic solutions, launched DUROLANE, a single-injection joint-fluid osteoarthritis (OA) treatment, in Malaysia, and has chosen Athrotech as its exclusive distributor.

    Collagen and Hyaluronic Acid Intra-Articular Injections Market Segmentation

    Collagen and Hyaluronic Acid Intra-Articular Injections by Product Type Outlook

    • Hyaluronic Acid Injection
      • Single Injection
      • Multiple Injection
    • Collagen Injection
    • Combination of Hyaluronic Acid and Collagen

    Collagen and Hyaluronic Acid Intra-Articular Injections by Application Outlook

    • Knee Osteoarthritis
    • Joint Pain
    • Veterinary Applications
    • Post-Operative Recovery
    • Others

    Collagen and Hyaluronic Acid Intra-Articular Injections by Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Collagen and Hyaluronic Acid Intra-Articular Injections Regional Outlook

    • North America
      • US
      • Canada
    • Europe
      • Germany
      • UK
      • France
      • Russia
      • Italy
      • Spain
      • Rest of Europe
    • Asia-Pacific
      • China
      • India
      • Japan
      • South Korea
      • Malaysia
      • Thailand
      • Indonesia
      • Rest of Asia-Pacific
    • Latin America
      • Brazil
      • Mexico
      • Argentina
      • Rest of Latin America
    • Middle East & Africa
      • GCC Countries
      • South Africa
      • Rest of Middle East & Africa

    Future Outlook

    Collagen Hyaluronic Acid Intra Articular Injections Market Future Outlook

    The Collagen and Hyaluronic Acid Intra-Articular Injections Market is projected to grow at a 6.78% CAGR from 2024 to 2035, driven by rising demand for minimally invasive treatments and advancements in injection technologies.

    New opportunities lie in:

    • Develop personalized injection therapies targeting specific joint conditions.
    • Invest in R&D for novel formulations enhancing efficacy and patient compliance.
    • Expand distribution channels in emerging markets to capture untapped customer bases.

    By 2035, the market is expected to achieve substantial growth, reflecting increased adoption and innovation in treatment options.

    Market Segmentation

    Regional Outlook

    • US
    • Canada

    Collagen and Hyaluronic Acid Intra-Articular Injections Regional Outlook

    • US
    • Canada

    Collagen and Hyaluronic Acid Intra-Articular Injections by Application Outlook

    • Knee Osteoarthritis
    • Joint Pain
    • Veterinary Applications
    • Post-Operative Recovery
    • Others

    Collagen and Hyaluronic Acid Intra-Articular Injections by Product Type Outlook

    • Single Injection
    • Multiple Injection

    Collagen and Hyaluronic Acid Intra-Articular Injections by Distribution Channel Outlook

    • Hospital Pharmacies
    • Retail Pharmacies
    • Online Pharmacies

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024 USD 3.04 Billion
    Market Size 2025 USD 3.28 Billion
    Market Size 2035 USD 6.32 Billion
    Compound Annual Growth Rate (CAGR) 6.15% (2025-2035)
    Base Year 2024
    Forecast Period 2025-2035
    Historical Data 2019-2023
    Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Segments Covered By Product Type, By Application, By Distribution Channel
    Geographies Covered North America, Europe, Asia Pacific, Latin America, Middle East & Africa
    Countries Covered The US, Canada, Germany, UK, France, Russia, Italy, Spain, China, India, Japan, South Korea, Malaysia, Thailand, Indonesia, Brazil, Mexico, Argentina, GCC Countries, South Africa
    Key Companies Profiled Seikagaku Corporation, Bioventus, Inc., Anika Therapeutics, Inc., Zimmer Biomet, Sanofi, Teva Pharmaceutical Industries Ltd., Ferring B.V., Dr. Reddy's Laboratories Ltd., Fidia Farmaceutici S.p.A., Semical Biosurgery, Avanos Medical, Inc., Maxigen Biotech Inc. (MBI)
    Key Market Opportunities ·         Growing Demand for Minimally Invasive Treatments
    Key Market Dynamics ·         Rising Prevalence of Osteoarthritis and Joint Disorders ·         Growing Aging Population

    FAQs

    How much is the Collagen and Hyaluronic Acid Intra-Articular Injections Market?

    USD 3.04 Billion is the Collagen and Hyaluronic Acid Intra-Articular Injections Market in 2024

    Which Product Type holds the largest market share?

    The Hyaluronic Acid Injection segment by Product Type holds the largest market share and grows at a CAGR of 6.34 % during the forecast period.

    Which region holds the largest market share in the Collagen and Hyaluronic Acid Intra-Articular Injections Market?

    North America holds the largest market share in the Collagen and Hyaluronic Acid Intra-Articular Injections Market.

    Who are the prominent players in the Collagen and Hyaluronic Acid Intra-Articular Injections Market?

    Seikagaku Corporation, Bioventus, Inc., Anika Therapeutics, Inc., Zimmer Biomet, Sanofi, Teva Pharmaceutical Industries Ltd., Ferring B.V., Dr. Reddy's Laboratories Ltd., Fidia Farmaceutici S.p.A., Semical Biosurgery, Avanos Medical, Inc., Maxigen Biotech Inc. (MBI) are prominent players in the Collagen and Hyaluronic Acid Intra-Articular Injections Market.

    Which Application segment led the Collagen and Hyaluronic Acid Intra-Articular Injections Market?

    The Knee Osteoarthritis segment dominated the market in 2024.

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