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Chiral chemicals, a specific group of chemicals with unique structures, are used in making various products like medicines, agricultural chemicals, and more. The traditional way of making these chemicals is not very efficient, using a lot of materials and toxic substances, which also requires a significant amount of energy. There's a better approach called biocatalytic synthesis, where special catalysts derived from renewable resources are used. This method is more eco-friendly, requires fewer toxic substances, and operates under milder conditions. The KYROBIO project in the European Union is working on improving this process by developing additional enzymes, expanding the range of reactions these catalysts can perform. This advancement is crucial for European industries to create valuable chiral molecules. Using this biocatalytic technology not only benefits the chemical industry but also aligns with environmental concerns and strict government rules.
In the next five years, the pharmaceutical market in Southeast Asia is expected to grow rapidly, with an annual increase of over 11%, reaching USD 40 billion in sales by 2020. This makes it one of the fastest-growing pharmaceutical markets globally. The Southeast Asian region presents great opportunities for pharmaceutical companies that can combine good manufacturing practices, competitive pricing, and a smart export strategy. South Asian pharmaceutical companies stand to gain from increased healthcare spending, a growing elderly population, higher instances of lifestyle-related diseases, and an overall rise in GDP per capita. Thailand, in particular, is witnessing a rapid increase in its aging population, with 13% of the population (10.3 million people) being above 60 years old. By 2025, this demographic is expected to make up 25% of the total population, following similar trends in Indonesia and Malaysia.
Governments in South Asia are recognizing the importance of innovation to sustain economic growth. Thailand, for instance, has launched the "Thailand 4.0" initiative to shift from being a mere manufacturing hub to becoming an innovation hub. The country has set up state-of-the-art facilities in the Thailand Science Park, focusing on clean rooms, advanced labs, and high-performance technologies. Foreign companies are increasingly partnering and investing in domestic companies to upgrade production technology. In Vietnam, STADA, a German company, has invested significantly in Pymepharmcov, one of the approved facilities. Indonesia is also expecting about USD 20 billion in foreign investments over the next five years. Singapore, on the other hand, has attracted investments from major pharmaceutical companies like GSK, WuXi Biologic, and Novartis, totaling hundreds of millions of dollars for advanced manufacturing facilities.
Covered Aspects:
| Report Attribute/Metric | Details |
|---|---|
| Market Opportunities | Biocatalytic chiral chemical synthesis is allowing marketing players to capture the untapped market. |
| Market Dynamics | Increased need from the healthcare and pharma sector |
Chiral Chemicals Market Highlights:
Global Chiral Chemicals Market Overview
Chiral Chemicals Market Size was valued at USD 67.75 Billion in 2023. The Chiral Chemicals industry is projected to grow from USD 75.37 Billion in 2024 to USD 158.97 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.78% during the forecast period (2024 - 2032). Increased need from the pharmaceutical sector and development in chemical industries are the key market drivers contributing to market growth and development.
Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review
Chiral Chemicals Market Trends
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Growing need from the pharmaceutical sector is driving the market growth
The rising need from the pharmaceutical sector drives the market CAGR for chiral chemicals. Chiral compounds play an important role in medication production and development. Over fifty percent of the medications in use today are chiral chemicals. The interaction of medications with targets in biology, such as nucleic acids, proteins, and membranes, determines their pharmacological activity. As a result, the pharmaceutical business's expansion and rising medicine demand will likely drive the development of the worldwide chiral chemicals industry throughout the projected timeframe.
Additionally, chiral compounds are a class of chiral synthons used in producing goods, pharmaceuticals, agricultural chemicals, and various other non-pharmaceutical uses. The traditional synthetic technique could be more efficient in terms of material utilization. It necessitates the use of an abundance of organic solvents that contain very hazardous metals, leading to an energy-intensive expenditure. Implementing biocatalytic benefit technology will bring the chemical sector to the frontline of growth in the economy of the nation as a whole. Pharmaceutical manufacturing is the most common use for chiral compounds. Chiral compounds employed in the pharmaceutical business differ in pharmacological and their impact on biological creatures due to their impacts and superior qualities.
The COVID-19 epidemic has substantially influenced chemical and materials supply networks, trade, and manufacturing processes. Manufacturing operations have been disrupted as a consequence of a shutdown. To prevent the spread of COVID-19, market participants have had to stop manufacturing facilities or run them at less-than-ideal capacity. This has resulted in substantial interruptions in manufacturing and trade restrictions, impacting the availability of Chiral Chemicals entering the marketplace. Chiral Chemicals are essential in the manufacture of medicines and agrochemicals. Because these sectors fall under vital services, several major players have maintained manufacturing at their locations while taking precautionary precautions and applying limitations on travel. Looking at the worldwide picture, several countries have relaxed limitations and made it easier to get Chiral Chemicals. Furthermore, several firms have concentrated on producing novel products to combat COVID-19.
For instance, agriculture and food-related businesses in the United States produced around 5.2% of the total GDP in 2020, based on the US Ministry of Agriculture. In addition, according to UK national data, seed output is expected to expand by 17% in 2020, whereas protection for plant manufacturing is expected to rise by 10%. Also, OECD reports that the total worth of farm output in Japan in 2019 was USD 84,162 million, a 2.63% increase from USD 81,999 in 2018. This will increase the need for chiral chemicals further. Thus, it is anticipated that demand for Chiral Chemicals will increase throughout the projection timeframe due to the rising need from the pharmaceutical sector. Thus, driving the Chiral Chemicals market revenue.
Chiral Chemicals Market Segment Insights
Chiral Chemicals Technology Insights
The Chiral Chemicals market segmentation, based on technology, includes traditional separation method, asymmetric preparation method, and biological separation method. The traditional separation method segment dominated the market, accounting for 51% of market revenue (USD 31.1 billion) in 2022. Traditional separation involves manually separating isomer and racemate settlement following diastereomerization. The asymmetric Preparation Method is expected to grow and expand rapidly during the projected timeframe. Growing preference for pharmaceutical applications that need the production of enantiomers and diastereomers with varied biological activity because of the asymmetric preparation procedure's high yield and cheap cost.
Figure 1: Chiral Chemicals Market, by Technology, 2022 & 2032 (USD Billion)
Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review
Chiral Chemicals Application Insights
The Chiral Chemicals market segmentation, based on Application, includes pharmaceutical, agrochemical, flavors and fragrances, and others. The pharmaceutical category generated the highest market revenue of about 62% (USD 37.8 billion) in 2022. The market for chiral compounds in this application area is expected to be propelled by the desire for enantiomerically pure substances in formulations for medicine in the pharmaceutical sector. Agrochemicals are expected to grow and expand significantly during the projected timeframe. The expanding population, in addition to a focus on enhancing the productivity of crops, is expected to boost product demand for agricultural chemicals in the future. Rising demand for sustainable agrochemicals that concentrate on certain aspects of plant health will broaden the application potential for chiral compounds in the agrochemicals category.
In 2017, Phenomenex Inc., a global leader in the discovery and manufacture of breakthrough technologies for the separation sciences, expanded their Lux chiral LC/SFC column family with new immobilized Lux 5µm and Lux 3µm i-Amylose-1 media. During the production of Lux immobilized media, a chemical crosslinking occurs between the polysaccharide and the silica support, resulting in a strong column that can survive a variety of powerful solvents such as DMSO, THF, Ethyl Acetate, and DCM.
Chiral Chemicals Regional Insights
By region, the research provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American Chiral Chemicals market will dominate during the projected timeframe, owing to technical breakthroughs and the presence of an established number of major enterprises, and increased demand for organically produced perfumes is expected to drive market development. In addition, the growing number of established pharmaceutical production firms will boost market growth in this region.
Further, the major countries studied in the market report are the US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.
Figure 2: Chiral Chemicals Market Share by Region 2022 (USD Billion)
Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review
Europe region’s Chiral Chemicals market accounts for the second-largest market share due to the increased healthcare cost, an aging population, and the prevalence of lifestyle-related illnesses, which will drive the market demand. Further, the German Chiral Chemicals market holds the largest market share, and the UK Chiral Chemicals market is expected to grow and expand rapidly in the European region during the projected timeframe.
The Asia-Pacific Chiral Chemicals Market is expected to grow and expand significantly quickly during the projected time frame. This is due to For pharmaceutical businesses successfully working with good manufacturing practices norms, affordable prices, and an export plan; the area offers attractive potential and contributes to overall market growth. Moreover, China’s Chiral Chemicals market dominates the market share, and the Indian Chiral Chemicals market is expected to grow and expand market revenue steadily in the Asia-Pacific region during the projected timeframe.
Chiral Chemicals Key Market Players & Competitive Insights
Leading market players invested heavily in research and development (R&D) to scale up their manufacturing units and product lines, which will help the Chiral Chemicals market grow worldwide. Market participants are also undertaking various organic or inorganic strategic approaches to strengthen and expand their footprint, with important market developments including new product portfolios, contractual deals, mergers and acquisitions, capital expenditure, higher investments, and strategic alliances with other organizations. Businesses are also coming up with marketing strategies such as digital marketing, social media influencing, and content marketing to increase their scope of profit earnings. The Chiral Chemicals industry must offer cost-effective and sustainable options to survive in a highly fragmented and dynamic market climate.
Manufacturing locally to minimize operational expenses and offer aftermarket services to customers is one of the key business strategies organizations use in the Chiral Chemicals industry to benefit customers and capture untapped market share and revenue. The Chiral Chemicals industry has recently offered significant advantages to the healthcare industry. Moreover, more industry participants are utilizing and adopting cutting-edge Technology has grown substantially. Major players in the Chiral Chemicals market, including BASF (Germany), Solvias AG (Germany), Stern Chemicals, Inc. (United States), Johnson Matthey Plc (United Kingdom), and W. R. Grace & Co.-Conn. (US), Chiral Quest (Suzhou) Co.Ltd. (China), Tyche Industries Limited (India), Nanjing Legend Pharmaceutical (China), The Dow Chemical Company (US), and Flamma S.p.A. (Italy). And others are attempting to expand market share and demand by investing in research and development (R&D) operations to produce sustainable and affordable solutions.
Daicel Chiral Technologies is a highly reliable provider of optical isomer extraction technologies for pharmaceutical businesses and university researchers. They began selling reagents in 2010. They provide chiral reagents with excellent chemical purity and optical purity thanks to advanced methods in asymmetric catalysts, chiral analysis, and chiral separation. Daicel Chiral Technologies will release CHIRALPAK IK in November 2021. This is one of the most powerful chiral chromatography stages in labs worldwide. CHIRALPAK IK provides additional divisions and improves existing separations produced with IG and additional selectors.
Cascade Chemistry specializes in discovering active medicinal ingredients, scale-up, and GMP manufacture. Cascade Chemistry's headquarters are located in Eugene, Oregon. They provide cost-effective and quick alternatives for the research & development, and manufacture of API cGMP formulations on a 1-10 kg scale, and their newly constructed plant will begin delivering higher capacity in 2022. In June 2021, Aceto purchased Cascade Chemistry, a producer of active pharmaceutical compounds and complex intermediates. It improved customer service and expanded its footprint in North America due to this purchase.
Key Companies in the Chiral Chemicals market include
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BASF (Germany)
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Solvias AG (Germany)
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Stern Chemicals Inc. (United States)
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Johnson Matthey Plc (United Kingdom)
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W. R. Grace & Co.-Conn. (US)
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Chiral Quest (Suzhou) Co.Ltd. (China)
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Tyche Industries Limited (India)
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Nanjing Legend Pharmaceutical (China)
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The Dow Chemical Company (US)
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Flamma S.p.A. (Italy)
Chiral Chemicals Industry Developments
November 2021: Daicel Chiral Technologies will release CHIRALPAK IK in November 2021. This is one of the most powerful chiral chromatography stages in labs worldwide. CHIRALPAK IK provides additional divisions and improves existing separations produced with IG and additional selectors.
June 2021: Aceto purchased Cascade Chemistry, which produces active pharmaceutical compounds and complex intermediates. It improved customer service and expanded its footprint in North America due to this purchase.
February 2016: Strem Chemicals, Inc. partnered with Chiral Technologies in February 2016 to supply Daicel's chiral reagents throughout the United States and Europe. This aided the corporation in expanding its line of offerings. Comparably, Chiral Technologies struck an exclusive distribution arrangement alongside Scanco International S.A. in July 2016 to expand its presence in South America.
Chiral Chemicals Market Segmentation
Chiral Chemicals Technology Outlook
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Traditional Separation Method
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Asymmetric Preparation Method
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Biological Separation Method
Chiral Chemicals Application Outlook
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Pharmaceutical
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Agrochemical
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Flavors and Fragrances
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Others
Chiral Chemicals Regional Outlook
- North America
- US
- Canada
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- China
- Japan
- India
- Australia
- South Korea
- Australia
- Rest of Asia-Pacific
- Rest of the World
- Middle East
- Africa
- Latin America
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