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    Cementless Total Knee Arthroplasty Market

    ID: MRFR/HC/25950-HCR
    128 Pages
    Garvit Vyas
    September 2025

    Cementless Total Knee Arthroplasty Market Research Report By Implant Design (Monoblock, Modular, Hybrid), By Fixation Mechanism (Porous Coating, Hydroxyapatite Coating, Plasma Spray), By Material (Titanium, Cobalt-Chromium, Polyethylene, Ceramic), By End-User Setting (Hospitals, Ambulatory Surgical Centers, Rehabilitation Centers), By Application (Primary Total Knee Arthroplasty, Revision Total Knee Arthroplasty) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2032

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    Cementless Total Knee Arthroplasty Market Research Report — Global Forecast till 2032 Infographic
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    Cementless Total Knee Arthroplasty Market Summary

    The Global Cementless Total Knee Arthroplasty Market is projected to grow significantly from 3.31 USD Billion in 2024 to 8.71 USD Billion by 2035.

    Key Market Trends & Highlights

    Cementless Total Knee Arthroplasty Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 9.2 percent from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 8.71 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 3.31 USD Billion, reflecting a strong foundation for future expansion.
    • Growing adoption of cementless total knee arthroplasty due to increasing patient preference for minimally invasive procedures is a major market driver.

    Market Size & Forecast

    2024 Market Size 3.31 (USD Billion)
    2035 Market Size 8.71 (USD Billion)
    CAGR (2025-2035) 9.2%

    Major Players

    Zimmer Biomet, Stryker, LimaCorporate S.p.A., Wright Medical, Waldemar Link, Medtronic, Biomet Orthopedic, Aesculap AG, Implantcast, Orthofix, DePuy Synthes, Smith Nephew, DJO Global, Exactech, Corin Group

    Cementless Total Knee Arthroplasty Market Trends

    The global cementless total knee arthroplasty market is driven by the rising incidence of osteoarthritis, increasing demand for joint replacement surgeries, and growing preference for cementless procedures due to reduced risk of infection and better long-term outcomes.

    Technological advancements, such as improved implant designs and materials, are also contributing to the market growth.

    Opportunities exist in expanding the market into emerging economies with a growing aging population and healthcare infrastructure.

    Additionally, research and development efforts focused on improving implant longevity and reducing revision rates hold promise for future growth.

    Recent trends include the adoption of patient-specific implants, the utilization of robotic-assisted surgery for greater precision, and the emergence of hybrid procedures combining cementless and cemented techniques to optimize implant stability.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    The increasing adoption of cementless total knee arthroplasty is reshaping surgical practices, as it appears to enhance patient outcomes and longevity of implants, thereby indicating a shift towards more biologically favorable solutions in orthopedic surgery.

    U.S. National Institutes of Health

    Cementless Total Knee Arthroplasty Market Drivers

    Market Growth Projections

    The Global Cementless Total Knee Arthroplasty Market Industry is expected to witness substantial growth over the next decade. With a projected market value of 3.31 USD Billion in 2024 and an anticipated increase to 8.71 USD Billion by 2035, the industry is poised for significant expansion. This growth is underpinned by a compound annual growth rate of 9.2% from 2025 to 2035, indicating a robust demand for innovative solutions in knee arthroplasty. Factors such as technological advancements, demographic shifts, and evolving patient preferences are likely to contribute to this upward trend, making the market an area of keen interest for stakeholders.

    Rising Geriatric Population

    The global demographic shift towards an aging population is a significant factor driving the Global Cementless Total Knee Arthroplasty Market Industry. As individuals age, the likelihood of developing knee-related issues increases, leading to a higher demand for knee replacement surgeries. By 2035, the market is projected to reach 8.71 USD Billion, underscoring the urgency of addressing the needs of this demographic. Healthcare systems are likely to adapt by incorporating more cementless options, which may provide enhanced stability and longevity of implants. This demographic trend suggests a sustained growth trajectory for the market in the coming years.

    Increasing Prevalence of Osteoarthritis

    The rising incidence of osteoarthritis globally is a primary driver for the Global Cementless Total Knee Arthroplasty Market Industry. As populations age, the demand for knee replacement surgeries is expected to surge. In 2024, the market is projected to reach 3.31 USD Billion, reflecting the growing need for effective treatment options. Osteoarthritis affects millions worldwide, leading to significant disability and impacting quality of life. This trend suggests that healthcare systems will increasingly prioritize cementless solutions, which offer potential benefits such as improved bone integration and reduced risk of implant loosening, thereby enhancing patient outcomes.

    Enhanced Patient Outcomes and Satisfaction

    Improved patient outcomes associated with cementless total knee arthroplasty are driving interest in the Global Cementless Total Knee Arthroplasty Market Industry. Studies indicate that patients receiving cementless implants often experience better functional recovery and lower rates of revision surgeries. This is particularly relevant as healthcare providers focus on quality of care and patient satisfaction metrics. The anticipated growth of the market, reaching 3.31 USD Billion in 2024, reflects this shift towards solutions that prioritize long-term success and patient well-being. As more positive clinical data emerges, the adoption of cementless techniques is likely to increase.

    Technological Advancements in Implant Design

    Innovations in implant design and materials are propelling the Global Cementless Total Knee Arthroplasty Market Industry forward. Recent advancements have led to the development of more biocompatible materials and improved surface coatings that enhance osseointegration. These technological improvements are likely to increase the adoption of cementless implants, as they may offer better long-term performance compared to traditional cemented options. The market is anticipated to grow significantly, with projections indicating a rise to 8.71 USD Billion by 2035. As surgeons become more familiar with these advancements, the shift towards cementless solutions is expected to accelerate.

    Growing Awareness of Minimally Invasive Techniques

    There is a notable increase in awareness regarding minimally invasive surgical techniques, which is influencing the Global Cementless Total Knee Arthroplasty Market Industry. Patients are increasingly seeking options that promise quicker recovery times and less postoperative pain. Cementless total knee arthroplasty aligns with these preferences, as it often involves less soft tissue disruption. This trend is likely to drive market growth, as more healthcare providers adopt these techniques to meet patient demands. The anticipated compound annual growth rate of 9.2% from 2025 to 2035 indicates a robust market expansion driven by these evolving patient expectations.

    Market Segment Insights

    Cementless Total Knee Arthroplasty Market Implant Design Insights

    The global cementless total knee arthroplasty market is segmented on the basis of Implant Design as Monoblock, Modular, and Hybrid. The Monoblock segment accounted for the largest share in the year 2023, and it is expected to dominate the market for the forecasted period.

    This is mainly because the usage of monoblock implants is increasing considerably since they provide better stability, the risk of loosening is reduced, and patient outcomes are also significantly enhanced.

    The single solid design of monoblock implants eliminates the need for multiple components and thus the failure of the single component is not a challenge with these implants.

    The Modular segment is expected to grow moderately for the forecasted period. The reason is that modular implants offer a flexibility option to orthopedic surgeons while customizing the implants to individual needs.

    Though the modular segment also serves as another major option for treating knee replacement patients, its growth rate would be lower than the monoblock segment due to the dominance of the monoblock segment.

    Cementless Total Knee Arthroplasty Market Fixation Mechanism Insights

    Porous Coating, Hydroxyapatite Coating, and Plasma Spray are the three main fixation mechanisms that are used in Cementless Total Knee Arthroplasty. Porous Coating is expected to be the leading mechanism, with more than half of the Global Cementless Total Knee Arthroplasty Market revenue by 2024.

    The increase in market share is attributed to better bone ingrowth, ensuring exceptional stability. Hydroxyapatite Coating, in turn, will develop rapidly as a result of the osteoconductive properties as well as the increasing demand for the ability to fixation and induce bone healing.

    Plasma Spray, in its turn, will have an increased demand due to the long-term fixation and increased durability in hard bone conditions.

    Thus, Global Cementless Total Knee Arthroplasty Market segmentation by Fixation Mechanism provides information that is essential for understanding the market, and, therefore, stakeholders must use this information correctly to capture emerging opportunities.

    Cementless Total Knee Arthroplasty Market Material Insights

    The Global Cementless Total Knee Arthroplasty Market is segmented by Material into Titanium, Cobalt-Chromium, Polyethylene, and Ceramic.

    Among these, the Titanium segment is expected to dominate the market in 2023, accounting for a revenue share of around 40%. This dominance is attributed to the excellent biocompatibility, high strength-to-weight ratio, and corrosion resistance of Titanium.

    Additionally, the rising demand for personalized implants and the increasing preference for minimally invasive surgical procedures are expected to drive the growth of the Titanium segment in the coming years.

    The Cobalt-Chromium segment is also expected to witness significant growth owing to its high strength, wear resistance, and biocompatibility.

    Polyethylene, on the other hand, is widely used in bearing surfaces due to its low friction and wear resistance. The Ceramic segment is expected to gain traction in the future due to its superior wear resistance, high strength, and biocompatibility.

    Cementless Total Knee Arthroplasty Market End-User Setting Insights

    The Global Cementless Total Knee Arthroplasty Market is segmented by End-User Setting into Hospitals, Ambulatory Surgical Centers, and Rehabilitation Centers. Hospitals account for the largest share of the market, followed by Ambulatory Surgical Centers and Rehabilitation Centers.

    The growth of the Hospitals segment is attributed to the increasing number of knee replacement surgeries being performed in hospitals. Ambulatory Surgical Centers are expected to witness significant growth due to the increasing preference for outpatient procedures.

    Rehabilitation Centers are expected to grow at a steady pace due to the growing demand for post-operative rehabilitation services.

    The Global Cementless Total Knee Arthroplasty Market revenue for Hospitals segment is projected to reach USD 1.5 billion by 2024, growing at a CAGR of 7.5%.

    The market for Ambulatory Surgical Centers is expected to grow at a CAGR of 8.2%, reaching USD 0.6 billion by 2024. The Rehabilitation Centers segment is expected to grow at a CAGR of 6.5%, reaching USD 0.4 billion by 2024.

    Cementless Total Knee Arthroplasty Market Application Insights

    The Global Cementless Total Knee Arthroplasty Market Segmentation by Application includes Primary Total Knee Arthroplasty and Revision Total Knee Arthroplasty. Primary Total Knee Arthroplasty is more prevalent, accounting for a larger share of the market revenue.

    This is attributed to the increasing incidence of osteoarthritis, which is the leading cause of total knee arthroplasty.

    Revision Total Knee Arthroplasty, on the other hand, is performed to address complications or failures of a previous knee replacement surgery.

    The rising number of primary knee arthroplasty procedures and the growing demand for revision surgeries are expected to drive the growth of the Cementless Total Knee Arthroplasty Market.

    Get more detailed insights about Cementless Total Knee Arthroplasty Market Research Report — Global Forecast till 2032

    Regional Insights

    The regional landscape of the Global Cementless Total Knee Arthroplasty Market presents distinct market dynamics and growth trajectories.

    North America holds a significant market share, driven by factors such as the high prevalence of knee osteoarthritis, the increasing geriatric population, and technological advancements.

    Europe follows closely, with a robust healthcare infrastructure and rising demand for minimally invasive surgical procedures. The APAC region is projected to witness substantial growth due to increasing healthcare expenditure, growing awareness, and rising disposable income.

    South America and MEA exhibit promising growth potential, fueled by improving healthcare access and government initiatives to enhance healthcare infrastructure.

    Cementless Total Knee Arthroplasty Market Regional Insights

    Key Players and Competitive Insights

    Major players in the Cementless Total Knee Arthroplasty Market are continuously introducing advanced products in order to expand their market presence. For instance, in 2023, Zimmer Biomet launched Persona Revision Tibial System, which is intended for use in revision total knee arthroplasty.

    The system is designed to facilitate a simplified, modular approach to revision knee arthroplasty. Leading Cementless Total Knee Arthroplasty Market players are also focusing on strategic collaborations and partnerships to enhance their market position.

    In 2023, Stryker entered into a distribution agreement with Aesculap Implant Systems, LLC, to distribute Aesculap's mobile-bearing and fixed-bearing cementless knee systems in the United States. Such partnerships enable companies to expand their product portfolio and reach new markets.

    One of the leading companies in the Cementless Total Knee Arthroplasty Market is Zimmer Biomet. The company offers a range of cementless knee implants, including the Persona Knee System and the NexGen Knee System.

    Zimmer Biomet's cementless knee implants are designed to provide long-term stability and durability. The company also offers a variety of educational and training programs for surgeons who use its products.

    Another major player in the Cementless Total Knee Arthroplasty Market is Stryker. The company offers a range of cementless knee implants, including the Triathlon Knee System and the Mako Robotic-Arm Assisted Surgery System.

    Stryker's cementless knee implants are designed to provide excellent clinical outcomes. The company also offers a strong portfolio of educational and training programs for surgeons who use its products.

    Key Companies in the Cementless Total Knee Arthroplasty Market market include

    Industry Developments

    Technological advancements, the rising prevalence of knee osteoarthritis, and the increasing geriatric population are key growth drivers.

    Recent news in the market includes

    In February 2023, Stryker launched the Triathlon Total Knee System with Phoenix C Femoral Component, offering improved stability and longevity.

    In March 2023, Zimmer Biomet received FDA approval for its Persona Revision Knee System, designed for complex revision knee surgeries.

    These developments indicate the market's commitment to innovation and improving patient outcomes.

    Future Outlook

    Cementless Total Knee Arthroplasty Market Future Outlook

    The Cementless Total Knee Arthroplasty Market is projected to grow at a 9.2% CAGR from 2024 to 2035, driven by technological advancements, increasing geriatric population, and rising demand for minimally invasive procedures.

    New opportunities lie in:

    • Develop innovative cementless implant designs to enhance patient outcomes and reduce recovery times.
    • Expand distribution networks in emerging markets to capture growing demand for knee arthroplasty solutions.
    • Invest in digital health technologies to improve preoperative planning and postoperative monitoring for patients.

    By 2035, the Cementless Total Knee Arthroplasty Market is expected to achieve substantial growth, reflecting evolving surgical practices and patient needs.

    Market Segmentation

    Cementless Total Knee Arthroplasty Market Material Outlook

    • Titanium
    • Cobalt-Chromium
    • Polyethylene
    • Ceramic

    Cementless Total Knee Arthroplasty Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Cementless Total Knee Arthroplasty Market Implant Design Outlook

    • Monoblock
    • Modular
    • Hybrid

    Cementless Total Knee Arthroplasty Market End-User Setting Outlook

    • Hospitals
    • Ambulatory Surgical Centers
    • Rehabilitation Centers
    • Primary Total Knee Arthroplasty
    • Revision Total Knee Arthroplasty

    Cementless Total Knee Arthroplasty Market Fixation Mechanism Outlook

    • Porous Coating
    • Hydroxyapatite Coating
    • Plasma Spray

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 2.99 (USD Billion)
    Market Size 2024 3.31 (USD Billion)
    Market Size 2032 6.84 (USD Billion)
    Compound Annual Growth Rate (CAGR) 8.40% (2024 - 2032)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2023
    Market Forecast Period 2024 - 2032
    Historical Data 2019 - 2023
    Market Forecast Units USD Billion
    Key Companies Profiled LimaCorporate S.p.A., Wright Medical, Waldemar Link, Medtronic, Stryker, Biomet Orthopedic, Aesculap AG, Implantcast, Orthofix, DePuy Synthes, Smith Nephew, DJO Global, Zimmer Biomet, Exactech, Corin Group
    Segments Covered Implant Design, Fixation Mechanism, Material, End-User Setting, Application, Regional
    Key Market Opportunities Osteoarthritis Prevalence Technological Advancements Increasing Patient Population Rising Geriatric Population Growing Demand in Emerging Economies
    Key Market Dynamics Aging population Technological advancements Increasing prevalence of osteoarthritis Rising demand for minimally invasive surgeries Growing healthcare expenditure
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the market size of the Global Cementless Total Knee Arthroplasty Market?

    The Global Cementless Total Knee Arthroplasty Market is anticipated to reach USD 6.84 billion by 2032, growing at a CAGR of 8.40% from 2024 to 2032.

    Which region is expected to dominate the Global Cementless Total Knee Arthroplasty Market?

    North America is expected to dominate the Global Cementless Total Knee Arthroplasty Market, accounting for a significant market share during the forecast period.

    What are the key factors driving the growth of the Global Cementless Total Knee Arthroplasty Market?

    The increasing prevalence of osteoarthritis, rising geriatric population, and technological advancements in knee arthroplasty are primarily driving the market growth.

    What are the major applications of Cementless Total Knee Arthroplasty?

    Cementless Total Knee Arthroplasty is primarily used in the treatment of osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis.

    Who are the key competitors in the Global Cementless Total Knee Arthroplasty Market?

    The major players operating in the Global Cementless Total Knee Arthroplasty Market include Zimmer Biomet, Stryker, Johnson Johnson, Smith Nephew, and Medtronic.

    What was the market size of the Global Cementless Total Knee Arthroplasty Market in 2023?

    The Global Cementless Total Knee Arthroplasty Market size was valued at USD 2.99 billion in 2023.

    What is the expected CAGR of the Global Cementless Total Knee Arthroplasty Market?

    The Global Cementless Total Knee Arthroplasty Market is projected to grow at a CAGR of 8.40% from 2024 to 2032.

    Which region is expected to witness the highest growth in the Global Cementless Total Knee Arthroplasty Market?

    Asia Pacific is anticipated to witness the highest growth in the Global Cementless Total Knee Arthroplasty Market during the forecast period.

    What are the challenges faced by the Global Cementless Total Knee Arthroplasty Market?

    The market faces challenges such as the high cost of procedures, stringent regulatory approvals, and potential complications associated with surgery.

    What are the opportunities for growth in the Global Cementless Total Knee Arthroplasty Market?

    Rising healthcare expenditure, increasing awareness about knee replacement surgeries, and technological advancements present growth opportunities for the market.

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