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    US Tissue Transglutaminase Test Market

    ID: MRFR/LS/18513-HCR
    100 Pages
    Rahul Gotadki
    September 2025

    US Tissue Transglutaminase Test Market Research Report By Type (Serological, Biopsy, others) and By End Users (Hospitals & Clinics, Homecare, Research Organisations, others) - Forecast to 2035

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    US Tissue Transglutaminase Test Market Research Report — Global Forecast till 2035 Infographic
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    Table of Contents

    US Tissue Transglutaminase Test Market Summary

    The US Tissue Transglutaminase Test market is poised for substantial growth, projected to reach 7128 USD Million by 2035.

    Key Market Trends & Highlights

    US Tissue Transglutaminase Test Key Trends and Highlights

    • The market valuation is expected to grow from 848 USD Million in 2024 to 7128 USD Million by 2035.
    • A compound annual growth rate (CAGR) of 21.35 percent is anticipated from 2025 to 2035.
    • The increasing prevalence of celiac disease is likely to drive demand for tissue transglutaminase tests in the United States.
    • Growing adoption of advanced diagnostic techniques due to rising awareness of autoimmune disorders is a major market driver.

    Market Size & Forecast

    2024 Market Size 848 (USD Million)
    2035 Market Size 7128 (USD Million)
    CAGR (2025-2035) 21.35%

    Major Players

    Siemens Healthineers, Biomerica, Cypress Diagnostics, Inova Diagnostics, DiaSorin, Scimedex Pharmaceuticals, Roche, HoffmannLa Roche, Thermo Fisher Scientific, Antu Diagnostics, F. HoffmannLa Roche AG, Ortho Clinical Diagnostics, Abbott Laboratories, Medac GmbH, Celerion

    US Tissue Transglutaminase Test Market Trends

    The US Tissue Transglutaminase Test Market is witnessing significant growth, driven primarily by the increasing prevalence of celiac disease and gluten-related disorders across the country. Many health organizations, including the Centers for Disease Control and Prevention (CDC), have reported a rise in autoimmune diseases, prompting healthcare providers to seek more reliable diagnostic tests like the tissue transglutaminase test for timely and accurate patient assessment.

    Furthermore, there is a greater emphasis on early diagnosis and management of these conditions, as undiscovered gluten intolerance can lead to severe health risks. With the advancements in point-of-care testing and the development of more precise testing methods, healthcare facilities are now more inclined to adopt these innovative solutions. The opportunities in the US market are also expanding with increased awareness and education among patients and healthcare professionals regarding gluten intolerance.

    As more people seek testing for celiac disease due to heightened knowledge of symptoms, manufacturers have the chance to enhance their product offerings and broaden their market reach. Additionally, there is a growing trend in e-health and telemedicine, enabling remote diagnostic services, which may incorporate the tissue transglutaminase test into broader health monitoring systems. In recent times, the emphasis on personalized medicine is shaping the direction of testing protocols and management strategies within the US healthcare system.

    This trend supports the integration of tissue transglutaminase testing within the broader context of tailored healthcare solutions, catering to individual patient profiles. As awareness increases and diagnostic technologies improve, the US Tissue Transglutaminase Test Market is likely to see continued expansion and innovation.

    US Tissue Transglutaminase Test Market Drivers

    Market Segment Insights

    Tissue Transglutaminase Test Market Type Insights

    The US Tissue Transglutaminase Test Market is experiencing robust growth, significantly driven by advancements in diagnostic procedures and the increasing prevalence of celiac disease across the region. This market is distinctively segmented by Type, incorporating various testing methodologies that are essential for accurate diagnosis and monitoring of gluten-related disorders. The Serological testing approach remains pivotal within this market landscape due to its non-invasive nature, offering timely and efficient results that are crucial for patient outcomes.

    This method typically incorporates enzyme-linked immunosorbent assay (ELISA) techniques, which have shown high sensitivity and specificity in detecting antibodies related to tissue transglutaminase, making it an integral part of clinical practice in the United States. On a different note, the Biopsy segment plays a critical role for specific cases where serological results may not provide conclusive evidence. It involves obtaining small samples of intestinal tissue to ascertain the degree of damage to the intestinal lining, thus offering invaluable data for healthcare providers in determining the appropriate management strategies.

    This invasive method, while less common than serological tests, is often employed in clinical scenarios that require comprehensive evaluation, solidifying its importance in the diagnostic process. The others segment encompasses various alternative testing procedures that cater to different patient profiles, maintaining its relevance as healthcare practices continue to evolve. This diversity in testing methods highlights the dynamic nature of the US Tissue Transglutaminase Test Market, where leveraging multiple testing approaches allows clinicians to provide tailored care based on individual patient needs.

    As the industry progresses, the understanding of each type’s strengths and applicability will be essential in refining diagnostic protocols and improving patient management, contributing to the overall growth of the US Tissue Transglutaminase Test Market.

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Tissue Transglutaminase Test Market End Users Insights

    The US Tissue Transglutaminase Test Market encompasses a diverse range of End Users that play a pivotal role in driving its growth. Hospitals and Clinics emerge as significant contributors, due to their central role in diagnosing celiac disease and related disorders. The burgeoning trend towards precise and rapid diagnostics in healthcare facilities amplifies their importance in this landscape.

    Homecare settings are gaining traction as more patients prefer at-home testing for convenience and privacy, thus contributing to increased market penetration.Research Organizations also represent a vital segment, as they facilitate advances in medical research and contribute to the refining of testing methodologies. Collectively, these segments form the backbone of the US Tissue Transglutaminase Test Market industry, showcasing a dynamic and evolving landscape that is characterized by an increasing demand for accurate diagnostic tools.

    Additionally, the interplay of technological advancements, improved healthcare policies, and rising awareness about gluten-related disorders continues to enhance growth opportunities across all these End User categories, further solidifying their significance in the market's trajectory.

    Get more detailed insights about US Tissue Transglutaminase Test Market Research Report — Global Forecast till 2035

    Regional Insights

    Key Players and Competitive Insights

    The US Tissue Transglutaminase Test Market is characterized by a dynamic landscape fueled by advancements in diagnostic technologies and an increasing demand for accurate serological testing for celiac disease. The competitive insights within this market reveal a range of players striving to establish their presence through innovative products, strategic collaborations, and expansion of market reach. The growing awareness of celiac disease and the importance of early diagnosis have created a conducive environment for companies developing tissue transglutaminase tests.

    Companies are investing in research and development to enhance the accuracy and efficiency of these tests, which is likely to intensify competition. The market is marked by a blend of established companies and emerging players, all vying for a share in response to the evolving healthcare trends and the growing need for reliable diagnostic solutions in the United States.

    Siemens Healthineers

    Siemens Healthineers stands out in the US Tissue Transglutaminase Test Market with a formidable reputation for delivering high-quality medical diagnostics. Known for its innovation and technological excellence, Siemens Healthineers leverages its extensive expertise in laboratory diagnostics to offer superior testing solutions. The company’s strengths lie in its strong R&D capabilities, allowing it to continuously enhance test performance and accuracy.

    With a robust distribution network, Siemens Healthineers has secured a significant market presence across the United States, ensuring its products are readily available to a wide range of healthcare providers. The integration of advanced technologies into their testing platforms not only improves the overall user experience but also strengthens their competitive advantage in a rapidly evolving market.

    Biomerica

    Biomerica is another key player in the US Tissue Transglutaminase Test Market, known for its focus on developing diagnostic products aimed at improving health outcomes. Biomerica specializes in offering a range of diagnostic tests related to celiac disease, contributing to its presence in the market. The company emphasizes innovation in its test development, working on delivering effective and user-friendly diagnostic solutions for healthcare providers.

    Biomerica’s strengths include its commitment to research and customer-centric product development, which allows for the timely introduction of new tests and solutions. The company also engages in strategic partnerships and collaborations to enhance its product offerings and expand its market footprint. While Biomerica continues to innovate, it remains dedicated to improving celiac disease diagnostics in the United States, thereby solidifying its competitive position in the market.

    Key Companies in the US Tissue Transglutaminase Test Market market include

    Industry Developments

    Recent developments in the US Tissue Transglutaminase Test Market are significantly shaping the landscape. Siemens Healthineers has been focusing on enhancing its diagnostic capabilities to cater to the growing demand for autoimmune disease testing, demonstrating a trend toward precision diagnostics in this sector. Biomerica and Inova Diagnostics are also gaining traction with their innovative enzyme-linked immunosorbent assays, contributing to the increasing adoption of antibody tests for celiac disease.

    In terms of market activity, DiaSorin announced its strategic acquisition of a diagnostic company in March 2023 to expand its product offerings in autoimmune testing, further indicating a consolidating market landscape. Additionally, Abbott Laboratories continues to invest heavily in Research and Development to address larger patient populations and improve testing accuracy. The market valuation for tissue transglutaminase tests has shown a growth trajectory, reflecting heightened awareness of celiac disease amongst healthcare professionals and patients alike.

    In recent years, regulatory approvals from the Food and Drug Administration have bolstered confidence in test methodologies, with significant advancements noted as early as September 2022, which have positioned major companies like Roche and Thermo Fisher Scientific favorably in this competitive market.

    Market Segmentation

    Tissue Transglutaminase Test Market Type Outlook

    • Serological
    • Biopsy
    • others

    Tissue Transglutaminase Test Market End Users Outlook

    • Hospitals & Clinics
    • Homecare
    • Research Organisations
    • others

    Report Scope

    Report Attribute/Metric Source: Details
    MARKET SIZE 2018 713.6(USD Million)
    MARKET SIZE 2024 848.0(USD Million)
    MARKET SIZE 2035 7128.0(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 21.353% (2025 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    MARKET FORECAST PERIOD 2025 - 2035
    HISTORICAL DATA 2019 - 2024
    MARKET FORECAST UNITS USD Million
    KEY COMPANIES PROFILED Siemens Healthineers, Biomerica, Cypress Diagnostics, Inova Diagnostics, DiaSorin, Scimedex Pharmaceuticals, Roche, HoffmannLa Roche, Thermo Fisher Scientific, Antu Diagnostics, F. HoffmannLa Roche AG, Ortho Clinical Diagnostics, Abbott Laboratories, Medac GmbH, Celerion
    SEGMENTS COVERED Type, End Users
    KEY MARKET OPPORTUNITIES Rising prevalence of celiac disease, Increased awareness and early diagnosis, Advancements in diagnostic technologies, Growth in point-of-care testing, Expanding applications in autoimmune disorders
    KEY MARKET DYNAMICS growing prevalence of celiac disease, increasing awareness and diagnosis, advancements in testing technology, rising demand for accurate results, favorable reimbursement policies
    COUNTRIES COVERED US

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the expected market size of the US Tissue Transglutaminase Test Market in 2024?

    The US Tissue Transglutaminase Test Market is anticipated to be valued at 848.0 USD Million in 2024.

    What is the projected market size for the US Tissue Transglutaminase Test Market by 2035?

    By 2035, the market is expected to reach a value of 7128.0 USD Million.

    What is the expected compound annual growth rate (CAGR) for the US Tissue Transglutaminase Test Market from 2025 to 2035?

    The market is expected to grow at a CAGR of 21.353% during the forecast period from 2025 to 2035.

    Which type of testing is projected to dominate the market in 2024?

    The Serological testing segment is expected to hold a significant share, valued at 350.0 USD Million in 2024.

    How much is the Biopsy segment projected to be valued in 2035?

    The Biopsy segment is expected to grow significantly, reaching a value of 3200.0 USD Million by 2035.

    What is the anticipated market size for 'others' segment in 2024?

    The 'others' segment of the US Tissue Transglutaminase Test Market is estimated to be valued at 98.0 USD Million in 2024.

    Who are some key players in the US Tissue Transglutaminase Test Market?

    Major players include Siemens Healthineers, Biomerica, DiaSorin, and Roche among others.

    What are the expected growth drivers for the US Tissue Transglutaminase Test Market?

    Factors such as increasing prevalence of celiac disease and advancements in diagnostic technologies are key growth drivers.

    How much will the Serological segment grow by 2035?

    The Serological segment is projected to expand to 3120.0 USD Million by 2035.

    What challenges might the US Tissue Transglutaminase Test Market face in the coming years?

    Challenges may include regulatory hurdles and competition from alternative diagnostic methods.

    1. EXECUTIVE SUMMARY
    2. Market Overview
    3. Key Findings
    4. Market Segmentation
    5. Competitive Landscape
    6. Challenges and Opportunities
    7. Future Outlook
    8. MARKET INTRODUCTION
    9. Definition
    10. Scope of the study
    11. Research Objective
    12. Assumption
    13. Limitations
    14. RESEARCH METHODOLOGY
    15. Overview
    16. Data Mining
    17. Secondary Research
    18. Primary Research
    19. Primary Interviews and Information Gathering Process
    20. Breakdown of Primary Respondents
    21. Forecasting Model
    22. Market Size Estimation
    23. Bottom-Up Approach
    24. Top-Down Approach
    25. Data Triangulation
    26. Validation
    27. MARKET DYNAMICS
    28. Overview
    29. Drivers
    30. Restraints
    31. Opportunities
    32. MARKET FACTOR ANALYSIS
    33. Value chain Analysis
    34. Porter's Five Forces Analysis
    35. Bargaining Power of Suppliers
    36. Bargaining Power of Buyers
    37. Threat of New Entrants
    38. Threat of Substitutes
    39. Intensity of Rivalry
    40. COVID-19 Impact Analysis
    41. Market Impact Analysis
    42. Regional Impact
    43. Opportunity and Threat Analysis
    44. US Tissue Transglutaminase Test Market, BY Type (USD Million)
    45. Serological
    46. Biopsy
    47. others
    48. US Tissue Transglutaminase Test Market, BY End Users (USD Million)
    49. Hospitals & Clinics
    50. Homecare
    51. Research Organisations
    52. others
    53. Competitive Landscape
    54. Overview
    55. Competitive Analysis
    56. Market share Analysis
    57. Major Growth Strategy in the Tissue Transglutaminase Test Market
    58. Competitive Benchmarking
    59. Leading Players in Terms of Number of Developments in the Tissue Transglutaminase Test Market
    60. Key developments and growth strategies
    61. New Product Launch/Service Deployment
    62. Merger & Acquisitions
    63. Joint Ventures
    64. Major Players Financial Matrix
    65. Sales and Operating Income
    66. Major Players R&D Expenditure. 2023
    67. Company Profiles
    68. Siemens Healthineers
    69. Financial Overview
    70. Products Offered
    71. Key Developments
    72. SWOT Analysis
    73. Key Strategies
    74. Biomerica
    75. Financial Overview
    76. Products Offered
    77. Key Developments
    78. SWOT Analysis
    79. Key Strategies
    80. Cypress Diagnostics
    81. Financial Overview
    82. Products Offered
    83. Key Developments
    84. SWOT Analysis
    85. Key Strategies
    86. Inova Diagnostics
    87. Financial Overview
    88. Products Offered
    89. Key Developments
    90. SWOT Analysis
    91. Key Strategies
    92. DiaSorin
    93. Financial Overview
    94. Products Offered
    95. Key Developments
    96. SWOT Analysis
    97. Key Strategies
    98. Scimedex Pharmaceuticals
    99. Financial Overview
    100. Products Offered
    101. Key Developments
    102. SWOT Analysis
    103. Key Strategies
    104. Roche
    105. Financial Overview
    106. Products Offered
    107. Key Developments
    108. SWOT Analysis
    109. Key Strategies
    110. HoffmannLa Roche
    111. Financial Overview
    112. Products Offered
    113. Key Developments
    114. SWOT Analysis
    115. Key Strategies
    116. Thermo Fisher Scientific
    117. Financial Overview
    118. Products Offered
    119. Key Developments
    120. SWOT Analysis
    121. Key Strategies
    122. Antu Diagnostics
    123. Financial Overview
    124. Products Offered
    125. Key Developments
    126. SWOT Analysis
    127. Key Strategies
    128. F. HoffmannLa Roche AG
    129. Financial Overview
    130. Products Offered
    131. Key Developments
    132. SWOT Analysis
    133. Key Strategies
    134. Ortho Clinical Diagnostics
    135. Financial Overview
    136. Products Offered
    137. Key Developments
    138. SWOT Analysis
    139. Key Strategies
    140. Abbott Laboratories
    141. Financial Overview
    142. Products Offered
    143. Key Developments
    144. SWOT Analysis
    145. Key Strategies
    146. Medac GmbH
    147. Financial Overview
    148. Products Offered
    149. Key Developments
    150. SWOT Analysis
    151. Key Strategies
    152. Celerion
    153. Financial Overview
    154. Products Offered
    155. Key Developments
    156. SWOT Analysis
    157. Key Strategies
    158. References
    159. Related Reports
    160. US Tissue Transglutaminase Test Market SIZE ESTIMATES & FORECAST, BY TYPE, 2019-2035 (USD Billions)
    161. US Tissue Transglutaminase Test Market SIZE ESTIMATES & FORECAST, BY END USERS, 2019-2035 (USD Billions)
    162. PRODUCT LAUNCH/PRODUCT DEVELOPMENT/APPROVAL
    163. ACQUISITION/PARTNERSHIP
    164. MARKET SYNOPSIS
    165. US TISSUE TRANSGLUTAMINASE TEST MARKET ANALYSIS BY TYPE
    166. US TISSUE TRANSGLUTAMINASE TEST MARKET ANALYSIS BY END USERS
    167. KEY BUYING CRITERIA OF TISSUE TRANSGLUTAMINASE TEST MARKET
    168. RESEARCH PROCESS OF MRFR
    169. DRO ANALYSIS OF TISSUE TRANSGLUTAMINASE TEST MARKET
    170. DRIVERS IMPACT ANALYSIS: TISSUE TRANSGLUTAMINASE TEST MARKET
    171. RESTRAINTS IMPACT ANALYSIS: TISSUE TRANSGLUTAMINASE TEST MARKET
    172. SUPPLY / VALUE CHAIN: TISSUE TRANSGLUTAMINASE TEST MARKET
    173. TISSUE TRANSGLUTAMINASE TEST MARKET, BY TYPE, 2025 (% SHARE)
    174. TISSUE TRANSGLUTAMINASE TEST MARKET, BY TYPE, 2019 TO 2035 (USD Billions)
    175. TISSUE TRANSGLUTAMINASE TEST MARKET, BY END USERS, 2025 (% SHARE)
    176. TISSUE TRANSGLUTAMINASE TEST MARKET, BY END USERS, 2019 TO 2035 (USD Billions)
    177. BENCHMARKING OF MAJOR COMPETITORS

    US Tissue Transglutaminase Test Market Segmentation

    • Tissue Transglutaminase Test Market By Type (USD Million, 2019-2035)

      • Serological
      • Biopsy
      • others
    • Tissue Transglutaminase Test Market By End Users (USD Million, 2019-2035)

      • Hospitals & Clinics
      • Homecare
      • Research Organisations
      • others

     

     

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    Customer Strories

    “I am very pleased with how market segments have been defined in a relevant way for my purposes (such as "Portable Freezers & refrigerators" and "last-mile"). In general the report is well structured. Thanks very much for your efforts.”

    Victoria Milne Founder
    Case Study

    Chemicals and Materials