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    US Solid Phase Extraction Market

    ID: MRFR/HC/12020-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    US Solid Phase Extraction Market Research Report By Type (SPE Disk, SPE Cartridge, Others) and By Application (Pharmaceutical Industries, Academic Research Institutes, Environmental, Hospitals Clinics, Others)-Forecast to 2035

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    US Solid Phase Extraction Market Infographic
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    US Solid Phase Extraction Market Summary

    As per MRFR analysis, the solid phase-extraction market size was estimated at 98.0 USD Million in 2024. The US solid phase-extraction market is projected to grow from 101.84 USD Million in 2025 to 149.6 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 3.92% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The US solid phase-extraction market is poised for growth driven by technological advancements and regulatory compliance.

    • Technological advancements in extraction techniques are enhancing efficiency and accuracy in analytical testing.
    • The largest segment in the US solid phase-extraction market is driven by the rising demand for analytical testing in environmental applications.
    • Sustainability initiatives are increasingly influencing market dynamics, particularly in the fastest-growing clinical diagnostics segment.
    • Key market drivers include the rising demand for analytical testing and increased focus on quality control, reflecting growing environmental concerns.

    Market Size & Forecast

    2024 Market Size 98.0 (USD Million)
    2035 Market Size 149.6 (USD Million)

    Major Players

    Agilent Technologies (US), Thermo Fisher Scientific (US), Merck KGaA (DE), Waters Corporation (US), Phenomenex (US), SPEX SamplePrep (US), Biotage AB (SE), Restek Corporation (US), Jiangsu Hualan (CN)

    US Solid Phase Extraction Market Trends

    The solid phase-extraction market is currently experiencing notable growth, driven by advancements in analytical techniques and increasing demand for high-quality sample preparation methods. This market is characterized by a diverse range of applications, including environmental testing, food safety, and pharmaceutical analysis. The emphasis on regulatory compliance and the need for accurate results are pushing laboratories to adopt solid phase-extraction methods, which offer enhanced sensitivity and specificity. Furthermore, the trend towards automation in laboratories is likely to streamline processes, making solid phase-extraction more accessible and efficient for various industries. In addition, the solid phase-extraction market is witnessing innovations in materials and technologies, which may lead to improved performance and cost-effectiveness. The development of new sorbents and extraction techniques appears to enhance the efficiency of sample preparation, catering to the evolving needs of researchers and analysts. As the focus on sustainability grows, there is a potential shift towards eco-friendly materials and methods within the market. Overall, the solid phase-extraction market is poised for continued expansion, driven by technological advancements and increasing awareness of the importance of reliable analytical results.

    Technological Advancements

    Recent innovations in solid phase-extraction technologies are enhancing the efficiency and effectiveness of sample preparation. New materials and methods are being developed, which may improve extraction performance and reduce processing times. This trend indicates a shift towards more sophisticated techniques that cater to the specific needs of various industries.

    Regulatory Compliance

    The solid phase-extraction market is increasingly influenced by stringent regulatory requirements across multiple sectors. Laboratories are compelled to adopt reliable and accurate sample preparation methods to meet these standards. This trend underscores the importance of solid phase-extraction in ensuring compliance with safety and quality regulations.

    Sustainability Initiatives

    There is a growing emphasis on sustainability within the solid phase-extraction market. The development of eco-friendly materials and extraction methods suggests a potential shift towards greener practices. This trend reflects the broader movement towards environmental responsibility in laboratory operations and product development.

    US Solid Phase Extraction Market Drivers

    Increased Focus on Quality Control

    Quality control remains a critical aspect of manufacturing and production processes, particularly in industries such as pharmaceuticals and food and beverage. The solid phase-extraction market is benefiting from this heightened focus, as companies strive to meet stringent quality standards. The implementation of solid phase-extraction methods allows for improved accuracy in detecting contaminants and ensuring product integrity. According to industry reports, the quality control market is expected to grow at a CAGR of 6% through 2027, which directly influences the demand for solid phase-extraction solutions. As organizations prioritize quality assurance, the solid phase-extraction market is likely to see sustained growth, driven by the need for reliable testing methodologies.

    Rising Demand for Analytical Testing

    The solid phase-extraction market is experiencing a notable increase in demand for analytical testing across various sectors, including pharmaceuticals, environmental monitoring, and food safety. This surge is driven by the need for accurate and reliable testing methods to ensure product safety and compliance with regulatory standards. In the pharmaceutical industry alone, the market for analytical testing is projected to reach approximately $20 billion by 2026, indicating a robust growth trajectory. As companies seek to enhance their testing capabilities, solid phase-extraction techniques are becoming essential for sample preparation, thereby propelling the market forward. The ability to efficiently isolate and concentrate analytes from complex matrices is a key factor contributing to the growth of the solid phase-extraction market.

    Emerging Applications in Clinical Diagnostics

    The solid phase-extraction market is witnessing a shift towards emerging applications in clinical diagnostics, particularly in the realm of personalized medicine and biomarker discovery. As healthcare evolves, there is a growing need for precise and efficient sample preparation techniques to analyze biological samples. The market for clinical diagnostics is projected to reach $70 billion by 2025, with solid phase-extraction playing a pivotal role in enhancing the accuracy of diagnostic tests. This trend suggests that the solid phase-extraction market will continue to expand as healthcare providers seek innovative solutions to improve patient outcomes. The ability to extract and analyze specific biomarkers is crucial for advancing personalized treatment approaches, thereby driving demand for solid phase-extraction technologies.

    Growing Environmental Concerns and Regulations

    Environmental concerns are driving regulatory changes that impact the solid phase-extraction market. As awareness of pollution and contamination rises, regulatory bodies are implementing stricter guidelines for environmental testing. This trend necessitates the use of reliable extraction methods to monitor pollutants in air, water, and soil samples. The solid phase-extraction market is positioned to benefit from these regulatory shifts, as it provides effective solutions for isolating and quantifying environmental contaminants. The market for environmental testing is expected to grow at a CAGR of 5% through 2028, indicating a robust demand for solid phase-extraction technologies. As regulations become more stringent, the solid phase-extraction market is likely to expand in response to the need for comprehensive environmental monitoring.

    Technological Innovations in Extraction Techniques

    Technological innovations are reshaping the landscape of the solid phase-extraction market, with advancements in materials and methodologies enhancing extraction efficiency and selectivity. The introduction of novel sorbents and automated systems is streamlining the extraction process, making it more accessible to laboratories of all sizes. These innovations not only improve the speed and accuracy of sample preparation but also reduce costs associated with traditional methods. As laboratories increasingly adopt these advanced technologies, the solid phase-extraction market is likely to experience significant growth. The integration of automation and artificial intelligence in extraction processes could further optimize workflows, suggesting a promising future for the solid phase-extraction market.

    Market Segment Insights

    By Type: SPE Cartridge (Largest) vs. SPE Disk (Fastest-Growing)

    In the US solid phase-extraction market, the SPE Cartridge segment holds a significant portion of the market share, driven by its robust applications across various analytical processes. This segment is preferred for its efficiency in extracting analytes from complex matrices, making it a cornerstone in laboratories. In contrast, the SPE Disk segment, while smaller in share, is rapidly gaining ground due to its suitability for larger sample volumes and lower solvent consumption, appealing to environmental and cost-conscious users. Growth trends indicate an increasing demand for SPE solutions, particularly in drug testing and environmental analysis. The rise of stringent regulatory standards and a growing emphasis on accurate data quantification are fueling the adoption of advanced SPE technologies. Moreover, innovations that enhance the recovery rates and speed of analysis are enabling the SPE Disk segment to emerge as a compelling choice for laboratories looking to optimize their workflows.

    SPE Cartridge (Dominant) vs. SPE Disk (Emerging)

    The SPE Cartridge segment is a dominant force in the market, characterized by its versatile applications and proven performance in diverse analytical tasks, from pharmaceuticals to environmental testing. It offers high recovery rates and is particularly valued for its ease of use and reliability. Conversely, the SPE Disk segment is emerging with its ability to handle larger sample volumes, providing a more efficient alternative for laboratories aiming to enhance throughput. While the SPE Disk is still in the growth phase, its increased adoption can be attributed to the rising demands for eco-friendly processes and cost efficiency in solvent use, making it a strong contender in the market.

    By Application: Pharmaceutical Industries (Largest) vs. Environmental (Fastest-Growing)

    In the US solid phase-extraction market, the application segment is dominated by the pharmaceutical industries, which hold the largest market share due to the increasing demand for high-purity compounds and robust analytical methods. Academic and research institutes also contribute significantly, driven by research activities and the need for advanced extraction techniques. Meanwhile, the environmental application is gaining traction as regulatory pressures and public awareness on environmental contamination increase. Growth trends in the application segment are primarily fueled by innovations in solid phase-extraction technologies and the expanding scope of applications across various sectors. Hospitals and clinics are increasingly adopting these technologies for diagnostic and therapeutic purposes. Additionally, the rise of environmental testing, driven by stringent regulations, is expected to propel further growth. Investments in research and development are likely to enhance capabilities and efficiency, impacting future market dynamics positively.

    Pharmaceutical Industries (Dominant) vs. Environmental (Emerging)

    The pharmaceutical industries segment is characterized by its extensive use of solid phase-extraction methods to ensure the purity and accuracy of drugs and compounds. This segment is well-established with strong regulatory compliance and a focus on high-quality standards, making it the dominant player in the application spectrum. In contrast, the environmental segment, although emerging, is rapidly developing due to increasing concerns about pollution and the need for rigorous testing. While the pharmaceutical industry leverages solid phase-extraction for regulatory approvals and quality assurance, the environmental sector is seeing innovations tailored to detect and analyze contaminants, reflecting its dynamic evolution in response to regulatory changes.

    Get more detailed insights about US Solid Phase Extraction Market

    Key Players and Competitive Insights

    The solid phase-extraction market in the US is characterized by a competitive landscape that is increasingly shaped by innovation, strategic partnerships, and a focus on sustainability. Key players such as Agilent Technologies (US), Thermo Fisher Scientific (US), and Waters Corporation (US) are at the forefront, leveraging their technological expertise to enhance product offerings and expand market reach. Agilent Technologies (US) emphasizes innovation in analytical chemistry, while Thermo Fisher Scientific (US) focuses on integrating advanced technologies into their extraction processes. Waters Corporation (US) appears to be concentrating on developing environmentally friendly extraction solutions, which aligns with the growing demand for sustainable practices in laboratory operations. Collectively, these strategies contribute to a dynamic competitive environment, where differentiation is increasingly based on technological advancement and sustainability initiatives.

    In terms of business tactics, companies are localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure is moderately fragmented, with several players vying for market share. However, the influence of major companies is substantial, as they set industry standards and drive innovation. This competitive structure allows for a diverse range of products and services, catering to various customer needs while fostering a culture of continuous improvement and adaptation.

    In October 2025, Agilent Technologies (US) announced the launch of a new line of solid phase-extraction products designed to improve efficiency and reduce solvent usage. This strategic move is significant as it not only addresses the growing regulatory pressures for sustainability but also positions Agilent as a leader in environmentally conscious laboratory practices. By focusing on reducing the environmental impact of their products, Agilent is likely to attract a broader customer base that prioritizes sustainability in their procurement decisions.

    In September 2025, Thermo Fisher Scientific (US) expanded its partnership with a leading biotechnology firm to enhance its solid phase-extraction capabilities. This collaboration aims to integrate cutting-edge technologies into their extraction processes, thereby improving the accuracy and reliability of results. The strategic importance of this partnership lies in its potential to accelerate product development and enhance Thermo Fisher's competitive edge in a rapidly evolving market.

    In August 2025, Waters Corporation (US) unveiled a new digital platform that utilizes AI to optimize solid phase-extraction workflows. This innovation is crucial as it reflects the ongoing trend towards digitalization in laboratory processes. By harnessing AI, Waters is likely to improve operational efficiency and provide customers with enhanced data analytics capabilities, thereby solidifying its position as a technology leader in the market.

    As of November 2025, current competitive trends are heavily influenced by digitalization, sustainability, and the integration of AI technologies. Strategic alliances are increasingly shaping the landscape, allowing companies to pool resources and expertise to drive innovation. The shift from price-based competition to a focus on technological advancement and supply chain reliability is evident. Moving forward, competitive differentiation will likely hinge on the ability to innovate and adapt to changing market demands, with a strong emphasis on sustainable practices and advanced technological solutions.

    Key Companies in the US Solid Phase Extraction Market market include

    Industry Developments

    The US Solid Phase Extraction Market has recently witnessed significant developments, with companies such as Agilent Technologies innovating to enhance extraction efficiency across various applications, including environmental monitoring and biotechnology. Merck KGaA has also been active in launching new extraction products that improve laboratory productivity. In mergers and acquisitions, Waters Corporation announced the acquisition of a complementary technology company in September 2023, bolstering its market position. Similarly, Thermo Fisher Scientific expanded its portfolio in August 2023 by acquiring a niche supplier of solid phase extraction products, focusing on enhancing its capabilities in laboratory technologies.

    The growth in the market valuation is evident, driven by the increasing demand for advanced analytical techniques in pharmaceuticals, environmental analysis, and food safety testing, reflecting a broader trend of technological evolution in analytical chemistry. In the past few years, events like the rise of stringent regulatory guidelines in July 2022 have propelled the market forward, urging laboratories to adopt more efficient methodologies for sample preparation. As companies innovate and consolidate, the competitive landscape of the US Solid Phase Extraction Market continues to evolve dynamically.

    Future Outlook

    US Solid Phase Extraction Market Future Outlook

    The solid phase-extraction market is projected to grow at 3.92% CAGR from 2024 to 2035, driven by advancements in analytical techniques and increasing demand for environmental testing.

    New opportunities lie in:

    • Development of automated solid phase-extraction systems for laboratories.
    • Expansion into emerging markets with tailored extraction solutions.
    • Partnerships with environmental agencies for regulatory compliance services.

    By 2035, the market is expected to achieve robust growth, driven by innovation and strategic partnerships.

    Market Segmentation

    US Solid Phase Extraction Market Type Outlook

    • SPE Disk
    • SPE Cartridge
    • Others

    US Solid Phase Extraction Market Application Outlook

    • Pharmaceutical Industries
    • Academic & Research Institutes
    • Environmental
    • Hospitals & Clinics
    • Others

    Report Scope

    MARKET SIZE 2024 98.0(USD Million)
    MARKET SIZE 2025 101.84(USD Million)
    MARKET SIZE 2035 149.6(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 3.92% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Agilent Technologies (US), Thermo Fisher Scientific (US), Merck KGaA (DE), Waters Corporation (US), Phenomenex (US), SPEX SamplePrep (US), Biotage AB (SE), Restek Corporation (US), Jiangsu Hualan (CN)
    Segments Covered Type, Application
    Key Market Opportunities Advancements in automation and miniaturization enhance efficiency in the solid phase-extraction market.
    Key Market Dynamics Technological advancements drive efficiency in solid phase-extraction, enhancing analytical capabilities across various industries.
    Countries Covered US

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    FAQs

    What is the expected market size of the US Solid Phase Extraction Market in 2024?

    The US Solid Phase Extraction Market is expected to be valued at 112.0 million USD in 2024.

    What is the projected market value for the US Solid Phase Extraction Market in 2035?

    By 2035, the US Solid Phase Extraction Market is projected to reach a valuation of 187.0 million USD.

    What is the expected CAGR for the US Solid Phase Extraction Market from 2025 to 2035?

    The expected CAGR for the US Solid Phase Extraction Market from 2025 to 2035 is 4.77 percent.

    What are the market values for SPE Disk in 2024 and 2035?

    The market value for SPE Disk is anticipated to be 35.0 million USD in 2024 and 58.0 million USD in 2035.

    What is the projected market size for SPE Cartridge in the US by 2035?

    The projected market size for SPE Cartridge is expected to be 85.0 million USD by 2035

    Which companies are the major players in the US Solid Phase Extraction Market?

    Key players in the market include companies such as Agilent Technologies, Merck KGaA, Phenomenex, and Thermo Fisher Scientific

    How much is the 'Others' type segment of the US Solid Phase Extraction Market valued at in 2024?

    The 'Others' type segment is valued at 27.0 million USD in 2024

    What challenges are anticipated in the US Solid Phase Extraction Market's growth?

    Challenges may include regulatory hurdles and competition among key players in the market.

    What key applications are driving the demand in the US Solid Phase Extraction Market?

    Key applications driving demand include pharmaceuticals, environmental testing, and food safety analysis

    What factors are expected to drive the growth of the US Solid Phase Extraction Market from 2025 to 2035?

    Growth is expected to be driven by increasing demand for analytical testing and advancements in extraction technologies

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