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US L-Citrulline Market

ID: MRFR/CnM/11835-HCR
111 Pages
Chitranshi Jaiswal
October 2025

US L-Citrulline Market Research Report: By Type (Power Type, Crystal Type), By Classification (Medical Grade, Food Grade) and By Application (Cosmetic & Personal Care, Food & Beverages, Pharmaceuticals, Agriculture, Animal Feed, Other) - Forecast to 2035

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US L-Citrulline Market Infographic
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US L-Citrulline Market Summary

As per Market Research Future analysis, the l citrulline market Size was estimated at 28.3 USD Million in 2024. The l citrulline market is projected to grow from 29.77 USD Million in 2025 to 49.5 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 5.2%1% during the forecast period 2025 - 2035.

Key Market Trends & Highlights

The US l citrulline market is experiencing robust growth driven by health trends and consumer preferences.

  • The market is witnessing a rising popularity of natural supplements, particularly among health-conscious consumers.
  • Athletic performance enhancement is a key focus, with l citrulline being favored by athletes and fitness enthusiasts.
  • Innovative product development is on the rise, leading to diverse formulations and delivery methods.
  • The growing demand for dietary supplements and increased awareness of health benefits are major drivers of market expansion.

Market Size & Forecast

2024 Market Size 28.3 (USD Million)
2035 Market Size 49.5 (USD Million)
CAGR (2025 - 2035) 5.21%

Major Players

NutraBio Labs (US), Kaged Muscle (US), BulkSupplements (US), NOW Foods (US), GNC Holdings (US), Jarrow Formulas (US), MyProtein (GB), Swanson Health Products (US)

US L-Citrulline Market Trends

The l citrulline market is currently experiencing notable growth, driven by increasing consumer awareness regarding health and wellness. This amino acid, primarily found in watermelon, is recognized for its potential benefits in enhancing athletic performance and improving cardiovascular health. As more individuals seek natural supplements to support their fitness goals, the demand for l citrulline is likely to rise. Additionally, the growing trend of plant-based diets may further bolster the market, as l citrulline is derived from natural sources, appealing to health-conscious consumers. Moreover, the l citrulline market is witnessing a shift towards innovative product formulations. Manufacturers are increasingly incorporating l citrulline into various dietary supplements, including pre-workout formulas and post-exercise recovery products. This diversification not only caters to a broader audience but also enhances the overall appeal of l citrulline as a versatile ingredient. As the market evolves, it appears that the focus on quality and efficacy will remain paramount, with consumers gravitating towards products that offer transparency in sourcing and formulation.

Rising Popularity of Natural Supplements

There is a growing trend towards natural supplements, with consumers increasingly favoring products derived from natural sources. This shift is likely to enhance the appeal of l citrulline, as it is sourced from watermelon and other natural ingredients, aligning with the preferences of health-conscious individuals.

Increased Focus on Athletic Performance

The l citrulline market is benefiting from a heightened interest in athletic performance enhancement. As more athletes and fitness enthusiasts seek effective supplements to improve endurance and recovery, l citrulline is gaining traction for its potential benefits in these areas.

Innovative Product Development

Manufacturers are actively exploring innovative formulations that incorporate l citrulline into various products. This trend reflects a broader strategy to diversify offerings, appealing to a wider consumer base and enhancing the market's overall growth potential.

Market Segment Insights

By Type: Powder Type (Largest) vs. Crystal Type (Fastest-Growing)

In the US l citrulline market, Powder Type holds a substantial market share due to its popularity among consumers seeking convenient and effective supplementation options. Its widespread availability across retail and online platforms, combined with strong brand recognition, has solidified its position as a dominant force in the market. Conversely, Crystal Type, while smaller in market size, is rapidly gaining traction, appealing to a niche audience interested in alternative forms of citrulline supplementation. The growth of the US l citrulline market is primarily driven by increasing awareness of the benefits of citrulline in enhancing athletic performance and recovery. Trends indicate that consumers are gravitating towards more versatile forms of citrulline, with Powder Type leading the charge. However, the rising interest in precision nutrition has significantly boosted the demand for Crystal Type, as consumers seek tailored solutions for their health and fitness goals. This trend is expected to intensify in the coming years, further positioning both types as essential elements in the citrulline landscape.

Powder Type (Dominant) vs. Crystal Type (Emerging)

Powder Type is integral to the US l citrulline market, appealing to a broad customer base due to its ease of use and effective delivery mechanism, favored primarily for its versatility across dietary regimens. It is characterized by a robust supply chain, with numerous brands offering variations in flavor and formulation to meet diverse preferences. On the other hand, Crystal Type, though currently a smaller player, is witnessing an upsurge in demand, especially among fitness enthusiasts who prioritize purity and bioavailability. This segment is gaining popularity for its unique offering—offering a concentrated form of citrulline that aligns well with the evolving trends of personalized nutrition and tailored supplementation, positioning it as an emerging choice among discerning consumers.

By Classification: Medical Grade (Largest) vs. Food Grade (Fastest-Growing)

In the US l citrulline market, the classification segment shows a distinct division in market share, with Medical Grade leading as the largest contributor. It appeals primarily to sectors such as pharmaceuticals and dietary supplements, where quality and safety are paramount. Food Grade follows, positioned as the fastest-growing segment, gaining traction primarily due to the rising health consciousness among consumers and increasing incorporation in functional foods. Growth trends indicate a robust rise in demand for Food Grade citrulline, driven by the health and wellness trend fostering its inclusion in various food and beverage applications. Additionally, innovations in product formulations aimed at providing health benefits play a significant role in driving both segments. Enhanced awareness of citrulline’s potential benefits continues to support expansion in these classifications, showcasing a promising outlook for future growth.

Medical Grade (Dominant) vs. Food Grade (Emerging)

The Medical Grade segment in the US l citrulline market is recognized for its stringent quality standards and regulatory compliance, making it the dominant classification in this sector. This grade is highly sought after for its application in the medical and health sectors, particularly in formulations requiring high purity and efficacy. Conversely, the Food Grade segment, although emerging, is gaining rapid popularity due to its use in dietary supplements and functional food products. As consumers increasingly seek health benefits from food sources, the Food Grade classification is becoming more prominent, supported by product innovation and expanding market opportunities. Both segments exhibit unique characteristics but are interlinked through the overarching health and wellness trends driving consumer choices.

By Application: Cosmetic & Personal Care (Largest) vs. Food & Beverages (Fastest-Growing)

The market share distribution in the US l citrulline market highlights Cosmetic & Personal Care as the largest segment, driven by the increasing demand for natural ingredients in skincare products. Following closely, the Food & Beverages segment is experiencing significant growth due to rising consumer awareness of health benefits associated with citrulline consumption. As a result, these segments play a crucial role in shaping the market dynamics and trends. Growth trends in the application segments reveal a robust trajectory for Food & Beverages, fueled by a shift towards functional foods and beverages. Meanwhile, Cosmetic & Personal Care continues to thrive as consumers seek products enriched with citrulline for anti-aging and rejuvenating benefits. Overall, innovation in product formulation and formulation techniques will further enhance the market's growth potential in these segments.

Cosmetic & Personal Care (Dominant) vs. Food & Beverages (Emerging)

Cosmetic & Personal Care remains the dominant application segment due to its established position within the beauty industry, where citrulline is highly valued for its skin-enhancing properties. This segment benefits from continuous innovation in formulations that incorporate natural ingredients. In contrast, Food & Beverages is emerging as a dynamic segment, gaining traction among health-conscious consumers seeking functional ingredients for improved well-being. The demand for citrulline-enriched products in this sector is driven by a rising inclination towards health and fitness, enabling brands to create innovative beverages and food items that cater to this growing consumer base.

Get more detailed insights about US L-Citrulline Market

Key Players and Competitive Insights

The l citrulline market is currently characterized by a dynamic competitive landscape, driven by increasing consumer awareness regarding health and fitness, alongside a growing demand for dietary supplements. Key players such as NutraBio Labs (US), Kaged Muscle (US), and NOW Foods (US) are strategically positioning themselves through innovation and product diversification. NutraBio Labs (US) emphasizes transparency and quality in its formulations, which resonates well with health-conscious consumers. Kaged Muscle (US) focuses on high-performance products, appealing to athletes and fitness enthusiasts, while NOW Foods (US) leverages its extensive distribution network to enhance market reach. Collectively, these strategies contribute to a moderately fragmented market structure, where competition is intensifying as companies seek to differentiate themselves through unique value propositions.

In terms of business tactics, companies are increasingly localizing manufacturing to reduce lead times and enhance supply chain efficiency. This approach not only mitigates risks associated with The l citrulline market demands. The competitive structure remains moderately fragmented, with several players vying for market share, yet the influence of major companies is palpable as they set trends and standards within the industry.

In October 2025, Kaged Muscle (US) announced the launch of a new line of plant-based supplements, including l citrulline, aimed at the growing vegan market. This strategic move is significant as it aligns with the increasing consumer shift towards plant-based nutrition, potentially capturing a new segment of health-conscious consumers who prioritize sustainability and ethical sourcing. By diversifying its product offerings, Kaged Muscle (US) not only enhances its market presence but also positions itself as a leader in innovation within the supplement space.

In September 2025, NOW Foods (US) expanded its product line to include organic l citrulline sourced from sustainable farms. This initiative reflects a broader trend towards sustainability in the supplement industry, appealing to environmentally conscious consumers. The strategic importance of this move lies in NOW Foods' ability to leverage its established brand reputation while addressing the growing demand for organic and sustainably sourced products, thereby enhancing customer loyalty and trust.

In August 2025, NutraBio Labs (US) entered into a partnership with a leading technology firm to integrate AI-driven analytics into its product development process. This collaboration aims to optimize formulation efficiency and enhance product efficacy based on real-time consumer feedback. The strategic implications of this partnership are profound, as it positions NutraBio Labs (US) at the forefront of technological innovation in the supplement industry, potentially leading to superior product offerings and improved market competitiveness.

As of November 2025, the l citrulline market is witnessing trends that emphasize digitalization, sustainability, and technological integration. Strategic alliances are increasingly shaping the competitive landscape, enabling companies to pool resources and expertise to drive innovation. Looking ahead, competitive differentiation is likely to evolve from traditional price-based competition towards a focus on innovation, technology, and supply chain reliability. Companies that can effectively leverage these trends will likely secure a competitive edge in an increasingly crowded marketplace.

Key Companies in the US L-Citrulline Market market include

Industry Developments

Recent developments in the US L-Citrulline Market have shown significant growth due to increasing consumer demand for dietary supplements and fitness products. Companies such as Now Foods, Creapure, Molecular Nutrition, Champion Nutrition, and NutraBio Labs are intensifying their product offerings. Noteworthy is the rising interest among athletes and fitness enthusiasts in L-Citrulline for its potential benefits in enhancing performance and recovery. In terms of mergers and acquisitions, there have been no widely reported activities involving these specific companies in recent months. However, GNC Holdings has seen a steady increase in sales, contributing to its enhanced market position.

The valuation of L-Citrulline products in the US is projected to expand, attributing to the ongoing trend towards health optimization and nutritional supplementation. Last year, in August 2022, MusclePharm launched new formulations featuring L-Citrulline, further pushing market boundaries. Additionally, public health organizations have recognized the benefits of amino acids such as L-Citrulline, promoting broader awareness and use among various demographics. The growing trends in e-commerce continue to drive accessibility and sales for companies like BulkSupplements and Cellucor, solidifying L-Citrulline's presence in the competitive dietary supplement market.

Future Outlook

US L-Citrulline Market Future Outlook

The l citrulline market is projected to grow at a 5.21% CAGR from 2024 to 2035, driven by increasing health awareness and demand for dietary supplements.

New opportunities lie in:

  • Development of innovative l citrulline formulations for sports nutrition products.
  • Expansion into e-commerce platforms for direct consumer sales.
  • Partnerships with fitness centers for exclusive product offerings.

By 2035, the l citrulline market is expected to achieve robust growth and increased market penetration.

Market Segmentation

US L-Citrulline Market Type Outlook

  • Powder Type
  • Crystal Type

US L-Citrulline Market Application Outlook

  • Cosmetic & Personal Care
  • Food & Beverages
  • Agriculture
  • Pharmaceuticals
  • Animal Feed
  • Other

US L-Citrulline Market Classification Outlook

  • Medical Grade
  • Food Grade

Report Scope

MARKET SIZE 202428.3(USD Million)
MARKET SIZE 202529.77(USD Million)
MARKET SIZE 203549.5(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR)5.21% (2024 - 2035)
REPORT COVERAGERevenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR2024
Market Forecast Period2025 - 2035
Historical Data2019 - 2024
Market Forecast UnitsUSD Million
Key Companies Profiled["NutraBio Labs (US)", "Kaged Muscle (US)", "BulkSupplements (US)", "NOW Foods (US)", "GNC Holdings (US)", "Jarrow Formulas (US)", "MyProtein (GB)", "Swanson Health Products (US)"]
Segments CoveredType, Classification, Application
Key Market OpportunitiesGrowing demand for dietary supplements enhances opportunities in the l citrulline market.
Key Market DynamicsRising consumer demand for performance supplements drives innovation and competition in the l citrulline market.
Countries CoveredUS

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FAQs

What is the expected market size of the US L-Citrulline Market in 2024?

The US L-Citrulline Market is expected to be valued at 30.87 USD Million in 2024.

What is the projected market size for the US L-Citrulline Market by 2035?

By 2035, the US L-Citrulline Market is projected to reach a value of 58.69 USD Million.

What is the expected compound annual growth rate (CAGR) for the US L-Citrulline Market from 2025 to 2035?

The CAGR for the US L-Citrulline Market during the period from 2025 to 2035 is expected to be 6.014%.

Which type of L-Citrulline holds the predominant market share in 2024?

In 2024, the Power Type is expected to be valued at 12.34 USD Million, indicating a significant portion of the market share.

What is the market value of the Crystal Type of L-Citrulline in 2024?

The Crystal Type segment of the US L-Citrulline Market is valued at 18.53 USD Million in 2024.

Who are the major players in the US L-Citrulline Market?

Key players in the market include Now Foods, Creapure, Molecular Nutrition, among others.

What is the anticipated market size for the Power Type of L-Citrulline by 2035?

The Power Type segment is anticipated to grow to 24.5 USD Million by 2035.

What will be the market value of the Crystal Type segment by 2035?

The Crystal Type segment is expected to reach a market value of 34.19 USD Million by 2035.

What growth opportunities exist in the US L-Citrulline Market?

There are emerging trends and growth opportunities driven by increasing applications in sports nutrition and supplements.

How will the overall US L-Citrulline Market growth rate be influenced by market dynamics?

The overall market growth is influenced by increasing awareness regarding health benefits and rising fitness trends.

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