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    US Dry Age-Related Macular Degeneration AMD Market

    ID: MRFR/LS/12338-HCR
    200 Pages
    Rahul Gotadki
    October 2025

    US Dry Age-Related Macular Degeneration (AMD) Market Research Report By Stage (Early Age-Related Macular Degeneration, Intermediate Age-Related Macular Degeneration, Late Age-Related Macular Degeneration), By Age Group (Above 75 years, Above 60 years, Above 40 years), By Diagnosis and Treatment (Treatment, Diagnosis), By Route of Administration (Oral, Injectables) and By End Users (Hospitals Clinics, Diagnostic Centers, Academic Research Institutes)-Forecast to 2035

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    US Dry Age-Related Macular Degeneration AMD Market Infographic
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    US Dry Age-Related Macular Degeneration AMD Market Summary

    As per MRFR analysis, the US dry age-related macular degeneration (AMD) market size was estimated at 1332.8 USD Million in 2024. The US dry age-related-macular-degeneration-amd market is projected to grow from 1443.42 USD Million in 2025 to 3203.89 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 8.3% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The US dry age-related macular degeneration market is poised for growth driven by innovative therapies and increasing patient awareness.

    • The emergence of novel therapies is reshaping treatment paradigms in the dry AMD market.
    • Increased patient awareness is driving demand for early diagnosis and intervention.
    • Technological advancements in diagnostics are enhancing the accuracy of AMD detection.
    • The aging population dynamics and rising healthcare expenditure are key drivers fueling market expansion.

    Market Size & Forecast

    2024 Market Size 1332.8 (USD Million)
    2035 Market Size 3203.89 (USD Million)

    Major Players

    Regeneron Pharmaceuticals (US), Novartis (CH), Roche (CH), Bayer (DE), Pfizer (US), Alcon (CH), Horizon Therapeutics (IE), Apellis Pharmaceuticals (US)

    US Dry Age-Related Macular Degeneration AMD Market Trends

    Currently, the dry age-related macular degeneration (AMD) market is experiencing notable shifts driven by advancements in treatment options and increasing awareness among the aging population. As the prevalence of this condition rises, healthcare providers are focusing on innovative therapies that may enhance patient outcomes. The integration of technology in diagnostics and treatment is also becoming more pronounced, suggesting a potential transformation in how this condition is managed. Furthermore, the emphasis on preventive care and lifestyle modifications appears to be gaining traction, indicating a holistic approach to managing dry age-related macular degeneration. In addition, the regulatory landscape is evolving, with agencies potentially streamlining approval processes for new therapies. This could lead to a more rapid introduction of effective treatments into the market. The collaboration between pharmaceutical companies and research institutions is likely to foster the development of novel solutions, which may address unmet needs in the patient population. Overall, the dry age-related-macular-degeneration-amd market seems poised for growth, driven by innovation, awareness, and a commitment to improving patient care.

    Emergence of Novel Therapies

    Recent developments in the dry age-related-macular-degeneration-amd market indicate a surge in innovative treatment options. These therapies, which may include new pharmacological agents and advanced delivery systems, are designed to slow disease progression and improve visual function. As research progresses, the introduction of these therapies could significantly alter the treatment landscape.

    Increased Patient Awareness

    There appears to be a growing awareness among the aging population regarding dry age-related macular degeneration. Educational initiatives and outreach programs are likely contributing to this trend, encouraging individuals to seek early diagnosis and treatment. This heightened awareness may lead to increased demand for healthcare services and interventions.

    Technological Advancements in Diagnostics

    The dry age-related-macular-degeneration-amd market is witnessing advancements in diagnostic technologies. Innovations such as enhanced imaging techniques and artificial intelligence applications are expected to improve the accuracy of diagnoses. These developments may facilitate earlier detection and more personalized treatment plans, ultimately benefiting patient outcomes.

    US Dry Age-Related Macular Degeneration AMD Market Drivers

    Aging Population Dynamics

    The demographic shift towards an older population in the US is a primary driver of the dry age-related macular degeneration (AMD) market. As individuals age, the prevalence of age-related eye diseases, including dry AMD, increases significantly. By 2030, it is projected that approximately 20% of the US population will be over 65 years old, leading to a higher incidence of AMD. This demographic trend suggests a growing need for effective treatment options and management strategies within the dry age-related-macular-degeneration-amd market. Furthermore, the aging population is likely to increase healthcare expenditures, which may further stimulate investment in research and development of new therapies and diagnostic tools tailored for this demographic. Thus, the aging population serves as a crucial catalyst for market growth.

    Rising Healthcare Expenditure

    In the US, healthcare expenditure continues to rise, which significantly impacts the dry age-related-macular-degeneration-amd market. In 2023, healthcare spending reached approximately $4.3 trillion, with a substantial portion allocated to eye care and vision-related treatments. This increase in spending reflects a growing recognition of the importance of addressing age-related conditions, including dry AMD. As more resources are directed towards innovative therapies and preventive measures, the market is likely to experience enhanced growth. Additionally, the willingness of patients and insurers to invest in advanced treatments may lead to a broader adoption of emerging therapies, thereby expanding the market landscape. The rising healthcare expenditure thus plays a pivotal role in shaping the future of the dry age-related-macular-degeneration-amd market.

    Increased Focus on Preventive Care

    The shift towards preventive care in the US healthcare system is influencing the dry age-related-macular-degeneration-amd market. Healthcare providers are increasingly emphasizing the importance of early detection and lifestyle modifications to mitigate the risk of developing AMD. This trend is supported by various public health campaigns aimed at educating the population about the risk factors associated with dry AMD, such as smoking and poor diet. As awareness grows, more individuals are likely to seek regular eye examinations and adopt healthier lifestyles, potentially reducing the incidence of AMD. Consequently, this focus on preventive care may lead to a more proactive approach in managing eye health, thereby impacting the dry age-related-macular-degeneration-amd market positively.

    Advancements in Research and Development

    Ongoing advancements in research and development are propelling the dry age-related-macular-degeneration-amd market forward. The US has seen a surge in clinical trials and studies focused on understanding the pathophysiology of dry AMD and developing novel therapeutic approaches. For instance, recent studies have explored the potential of gene therapy and stem cell treatments, which could revolutionize the management of this condition. The National Eye Institute has reported a significant increase in funding for AMD research, indicating a strong commitment to addressing this public health issue. As new findings emerge, they may lead to innovative treatment options that could reshape the dry age-related-macular-degeneration-amd market landscape. This focus on R&D is essential for fostering growth and improving patient outcomes.

    Technological Integration in Treatment Options

    Advanced technologies are reshaping treatment options in the dry age-related macular degeneration (AMD) market. Innovations such as telemedicine and digital health platforms are enhancing patient access to care and facilitating remote monitoring of AMD progression. Moreover, the development of artificial intelligence (AI) in diagnostic tools is improving the accuracy of early detection, which is crucial for effective management of dry AMD. As these technologies become more prevalent, they may lead to increased patient engagement and adherence to treatment regimens. The potential for technology to streamline care delivery and improve outcomes suggests a promising future for the dry age-related-macular-degeneration-amd market, as it adapts to the evolving landscape of healthcare.

    Market Segment Insights

    By Stages: Intermediate Age-Related Macular Degeneration (Largest) vs. Late Age-Related Macular Degeneration (Fastest-Growing)

    The US dry age-related-macular-degeneration-amd market showcases a varied distribution among the stages of the condition. Early Age-Related Macular Degeneration has a significant share but is overshadowed by Intermediate Age-Related Macular Degeneration, which leads the market due to its broader prevalence. Late Age-Related Macular Degeneration, while comprising a smaller portion of the market, represents a rapidly expanding segment, driven by increasing awareness and healthcare advancements. Growth trends indicate that the Intermediate Age-Related Macular Degeneration segment continues to benefit from earlier detection techniques and improved treatment options. As healthcare providers focus on proactive management strategies, the Late Age-Related Macular Degeneration segment is emerging with faster growth due to an aging population and rising incidence rates. Innovations in therapies are further catalyzing this dynamic landscape as patients seek effective solutions.

    Early Age-Related Macular Degeneration (Dominant) vs. Late Age-Related Macular Degeneration (Emerging)

    Early Age-Related Macular Degeneration is recognized as the dominant segment within the US dry age-related-macular-degeneration-amd market, characterized by early symptom onset and a significant base of diagnosed cases. This stage is often monitored to prevent progression to more severe forms. In contrast, Late Age-Related Macular Degeneration is an emerging segment, marked by advanced vision loss and a growing patient base due to demographic shifts. Patients with this stage face serious challenges, enhancing the urgency for effective treatment solutions. The market is responding to these needs through targeted therapies and supportive technologies aimed at improving the quality of life for those impacted by advanced forms of the condition.

    By Age Group: Above 75 Years (Largest) vs. Above 60 Years (Fastest-Growing)

    In the US dry age-related-macular-degeneration-amd market, the age group of individuals above 75 years constitutes the largest segment, commanding significant market share due to the higher prevalence of the condition in this demographic. The segment above 60 years, while smaller in comparison, is experiencing rapid growth, driven by increasing awareness and screening initiatives that target a broader age range, leading to earlier diagnoses. Growth trends for these age segments are influenced by demographic shifts and lifestyle factors. With the aging population in the US, the demand for treatments tailored to the elderly is expected to rise. Additionally, advancements in technology and innovative therapies are likely to attract more patients from the emerging segment of those aged above 60 years, as they seek proactive management of age-related eye conditions.

    Above 75 Years (Dominant) vs. Above 60 Years (Emerging)

    The segment above 75 years remains dominant in the US dry age-related-macular-degeneration-amd market due to the high incidence rates of AMD in this age group. Patients in this category often represent a significant portion of eye care visits and treatment regimens, making their needs crucial for healthcare providers. In contrast, the emerging segment of individuals above 60 years reflects a growing awareness of AMD and its implications, with increasing numbers seeking preventive measures and early treatment. This proactive approach is driven by enhanced education about eye health, thereby positioning this segment as an increasingly important target for marketing and healthcare strategies aimed at mitigating the progression of AMD.

    By Route of Administration: Injectables (Largest) vs. Oral (Fastest-Growing)

    In the US dry age-related-macular-degeneration-amd market, injectables hold the largest market share due to their effectiveness and direct delivery method that provides immediate results. This segment's prominence is driven by a preference for treatments that ensure optimal bioavailability and targeted action, making injectables the leading choice among healthcare providers and patients alike. On the other hand, oral formulations are emerging rapidly, reflecting a growing patient interest in convenient, non-invasive treatment options. This segment's growth is fueled by ongoing research and development to improve oral drug formulations, making them more appealing for long-term treatment. The increasing recognition of compliance benefits associated with oral medications positions this segment as the fastest-growing alternative in the market.

    Injectables (Dominant) vs. Oral (Emerging)

    Injectables are characterized by their direct administration for quicker therapeutic effects, making them a dominant force in the market. They typically involve advanced formulations that are designed for optimal absorption and immediate action, catering to patient needs who seek effective treatment for age-related macular degeneration. In contrast, oral medications are emerging as a convenient alternative, with advancements aimed at enhancing bioavailability and patient adherence. They offer an easy-to-administer option, appealing to those hesitant about needles. As manufacturers innovate in oral formulation technology, this segment is likely to capture a growing share of the market, balancing efficiency with patient comfort.

    By End Users: Hospitals & Clinics (Largest) vs. Diagnostic Centers (Fastest-Growing)

    In the US dry age-related-macular-degeneration-amd market, the distribution of market share among end users reveals that Hospitals & Clinics hold the largest share. This segment benefits from its established infrastructure and patient influx, making it a critical player in treatment delivery. On the other hand, Diagnostic Centers, while smaller in share, are rapidly gaining traction as specialists focus on early detection and preventive care, illustrating a shift toward targeted interventions. The growth trends in this segment are influenced by several factors, including an aging population that demands more frequent screenings and treatments. Furthermore, advancements in diagnostic technologies are driving the need for specialized centers, fostering innovation. Collaborative efforts between Hospitals, Clinics, and Academic Institutions are expected to propel the development and adoption of new treatment paradigms, enhancing patient outcomes and increasing market competitiveness.

    Hospitals & Clinics (Dominant) vs. Diagnostic Centers (Emerging)

    Hospitals & Clinics are recognized as the dominant force within the US dry age-related-macular-degeneration-amd market due to their comprehensive services and established patient networks. They provide a range of treatments and facilitate access to the latest technologies. In contrast, Diagnostic Centers are emerging as key players focusing on specific aspects of AMD management, emphasizing early diagnosis and tailored strategies. This segment is becoming increasingly vital as early detection leads to better management of the disease. Their adaptability and specialization in diagnostic procedures allow them to meet the rising demand for precision medicine. Together, these segments complement each other, with Hospitals & Clinics providing broad resources and Diagnostic Centers offering targeted care.

    Get more detailed insights about US Dry Age-Related Macular Degeneration AMD Market

    Key Players and Competitive Insights

    The dry age-related macular degeneration (AMD) market is characterized by a competitive landscape that is increasingly shaped by innovation and strategic partnerships. Key players such as Regeneron Pharmaceuticals (US), Novartis (CH), and Apellis Pharmaceuticals (US) are actively engaged in developing advanced therapies and expanding their market presence. Regeneron Pharmaceuticals (US) focuses on leveraging its expertise in biologics to enhance treatment efficacy, while Novartis (CH) emphasizes a diversified portfolio that includes both established and emerging therapies. Apellis Pharmaceuticals (US) is carving a niche with its novel complement inhibition approach, which appears to address unmet needs in the AMD treatment spectrum. Collectively, these strategies contribute to a dynamic environment where innovation and therapeutic advancements are paramount.

    In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure is moderately fragmented, with several players vying for market share. This fragmentation allows for a variety of treatment options, yet the influence of major companies remains significant, as they drive trends and set benchmarks for quality and efficacy in AMD therapies.

    In October 2025, Regeneron Pharmaceuticals (US) announced a collaboration with a leading biotechnology firm to develop a next-generation gene therapy for AMD. This strategic move is likely to bolster Regeneron's position in the market by expanding its therapeutic offerings and tapping into the growing demand for innovative treatment modalities. The collaboration underscores the importance of partnerships in accelerating research and development efforts in the AMD space.

    In September 2025, Novartis (CH) launched a new clinical trial for its latest AMD treatment, which incorporates a novel delivery system aimed at improving patient compliance. This initiative reflects Novartis's commitment to addressing patient needs and enhancing treatment accessibility. The trial's outcomes could potentially reshape treatment protocols and establish new standards in AMD management.

    In August 2025, Apellis Pharmaceuticals (US) secured a strategic partnership with a prominent research institution to explore combination therapies for AMD. This collaboration is indicative of a broader trend towards integrative approaches in treatment, which may enhance therapeutic outcomes and provide a competitive edge in a crowded market. By aligning with research entities, Apellis aims to leverage cutting-edge science to inform its product development pipeline.

    As of November 2025, the competitive trends in the dry AMD market are increasingly defined by digitalization, sustainability, and the integration of artificial intelligence (AI) in research and development. Strategic alliances are becoming a cornerstone of competitive strategy, enabling companies to pool resources and expertise. Looking ahead, the focus is likely to shift from price-based competition to differentiation through innovation, technology, and reliable supply chains. This evolution suggests that companies that prioritize R&D and strategic collaborations will be better positioned to thrive in an increasingly complex market.

    Key Companies in the US Dry Age-Related Macular Degeneration AMD Market market include

    Industry Developments

    Significant developments have occurred recently in the US Dry Age-Related Macular Degeneration (AMD) market. In July 2023, Apellis Pharmaceuticals announced the FDA approval of its innovative treatment, which has the potential to change the management approach for patients suffering from dry AMD. This approval marks a crucial milestone in the market, addressing an unmet need for effective treatment options. On the merger and acquisition front, in September 2023, Regeneron Pharmaceuticals acquired Iveric Bio, which is expected to bolster Regeneron's pipeline in AMD and optimize collaborative efforts to enhance patient outcomes.

    Furthermore, Genentech continues to advance its research and development initiatives, focusing on novel therapies that target AMD in light of the growing patient population projected by the CDC, which estimates that by 2030, nearly 3 million Americans will be affected by AMD. The competitive landscape is further evolving, with increased investment from companies such as Novartis and Kite Pharma, reinforcing their commitment to developing groundbreaking therapies for AMD. The surge in market valuation and research funding reflects a promising trajectory for advancements in AMD care in the US.

    Future Outlook

    US Dry Age-Related Macular Degeneration AMD Market Future Outlook

    The dry age-related macular degeneration market is projected to grow at an 8.3% CAGR from 2024 to 2035, driven by advancements in treatment options and increasing patient awareness.

    New opportunities lie in:

    • Development of telemedicine platforms for remote patient monitoring.
    • Investment in AI-driven diagnostic tools for early detection.
    • Expansion of personalized treatment plans based on genetic profiling.

    By 2035, the market is expected to achieve substantial growth, driven by innovative solutions and increased demand.

    Market Segmentation

    US Dry Age-Related Macular Degeneration AMD Market Stages Outlook

    • Early Age-Related Macular Degeneration
    • Intermediate Age-Related Macular Degeneration
    • Late Age-Related Macular Degeneration

    US Dry Age-Related Macular Degeneration AMD Market Age Group Outlook

    • Above 75 Years
    • Above 60 Years
    • Above 40 Years

    US Dry Age-Related Macular Degeneration AMD Market End Users Outlook

    • Hospitals & Clinics
    • Diagnostic Centers
    • Academic & Research Institutes

    US Dry Age-Related Macular Degeneration AMD Market Route of Administration Outlook

    • Oral
    • Injectables

    Report Scope

    MARKET SIZE 2024 1332.8(USD Million)
    MARKET SIZE 2025 1443.42(USD Million)
    MARKET SIZE 2035 3203.89(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 8.3% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Regeneron Pharmaceuticals (US), Novartis (CH), Roche (CH), Bayer (DE), Pfizer (US), Alcon (CH), Horizon Therapeutics (IE), Apellis Pharmaceuticals (US)
    Segments Covered Stages, Age Group, Route of Administration, End Users
    Key Market Opportunities Advancements in gene therapy and digital health solutions enhance treatment options in the dry age-related-macular-degeneration-amd market.
    Key Market Dynamics Rising demand for innovative therapies drives competition and regulatory scrutiny in the dry age-related macular degeneration market.
    Countries Covered US

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    FAQs

    What is the projected market size of the US Dry Age-Related Macular Degeneration (AMD) Market in 2024?

    In 2024, the US Dry Age-Related Macular Degeneration (AMD) Market is expected to be valued at 1.2 billion USD.

    What is the expected market value for the US Dry Age-Related Macular Degeneration (AMD) Market by 2035?

    By 2035, the market is projected to reach a value of 2.5 billion USD.

    What is the expected compound annual growth rate (CAGR) for the US Dry Age-Related Macular Degeneration (AMD) Market from 2025 to 2035?

    The market is expected to grow at a CAGR of 6.9% between 2025 and 2035.

    Which stage of Dry Age-Related Macular Degeneration holds the largest market share in 2024?

    In 2024, the intermediate age-related macular degeneration stage holds the largest market share at 0.5 billion USD.

    What is the market value for early age-related macular degeneration in 2035?

    The market value for early age-related macular degeneration is projected to be 0.9 billion USD in 2035.

    Who are the key players in the US Dry Age-Related Macular Degeneration (AMD) Market?

    Major players in the market include Kite Pharma, Genentech, and Regeneron Pharmaceuticals, among others.

    What is the market value for late age-related macular degeneration in 2024?

    In 2024, the market value for late age-related macular degeneration is expected to be 0.3 billion USD.

    What market trends are driving the growth of the US Dry Age-Related Macular Degeneration (AMD) Market?

    Technological advancements in treatment options and the increasing aging population are key trends driving market growth.

    What is the projected market value for intermediate age-related macular degeneration in 2035?

    The market value for intermediate age-related macular degeneration is expected to reach 1.1 billion USD in 2035.

    What challenges does the US Dry Age-Related Macular Degeneration (AMD) Market face?

    Challenges include high treatment costs and the need for early diagnosis and intervention.

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