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    US Active B12 Test Market

    ID: MRFR/LS/17736-HCR
    100 Pages
    Rahul Gotadki
    October 2025

    US Active B12 Test Market Research Report By Type (Elisa Assay, Enzyme Immunoassay, Others) and By Application (Folate Deficiency Anemia, Pernicious Anemia, Macrocytic Anemia, Others) - Forecast to 2035

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    US Active B12 Test Market Infographic
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    US Active B12 Test Market Summary

    As per MRFR analysis, the US Active B12-Test Market size was estimated at 0.974 USD Million in 2024. The US active b12-test market is projected to grow from 1.02 USD Million in 2025 to 1.57 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 4.41% during the forecast period 2025 - 2035.

    Key Market Trends & Highlights

    The US active B12-test market is experiencing notable growth driven by technological advancements and increased awareness of vitamin deficiencies.

    • The market is characterized by a heightened awareness of vitamin B12 deficiency among consumers.
    • Technological advancements in testing methodologies are enhancing the accuracy and efficiency of B12 testing.
    • Home testing solutions are gaining traction, appealing to consumers seeking convenience and immediate results.
    • Key market drivers include the growing demand for diagnostic testing and the rising geriatric population, which is likely to increase the need for B12 assessments.

    Market Size & Forecast

    2024 Market Size 0.974 (USD Million)
    2035 Market Size 1.57 (USD Million)

    Major Players

    Thermo Fisher Scientific (US), Roche Diagnostics (CH), Abbott Laboratories (US), Siemens Healthineers (DE), Danaher Corporation (US), Bio-Rad Laboratories (US), Ortho Clinical Diagnostics (US), PerkinElmer (US)

    US Active B12 Test Market Trends

    The active b12-test market is currently experiencing notable growth, driven by an increasing awareness of vitamin B12's role in health and wellness. This rise in consciousness is largely attributed to the growing prevalence of vitamin B12 deficiency, which has been linked to various health issues, including neurological disorders and anemia. As a result, healthcare providers are increasingly recommending active B12 testing as a preventive measure. Furthermore, advancements in testing technologies are enhancing the accuracy and efficiency of these tests, making them more accessible to both healthcare professionals and patients. This trend is likely to continue as the demand for reliable diagnostic tools increases. In addition, the active b12-test market is witnessing a shift towards home testing solutions. With the rise of telehealth and remote patient monitoring, individuals are seeking convenient ways to manage their health. Home testing kits for vitamin B12 levels are becoming more popular, allowing users to obtain results without the need for a clinical visit. This trend reflects a broader movement towards personalized healthcare, where patients take an active role in monitoring their health status. As the market evolves, it appears poised for further innovation and expansion, catering to the needs of a more health-conscious population.

    Increased Awareness of Vitamin B12 Deficiency

    There is a growing recognition of the health implications associated with vitamin B12 deficiency. This awareness is prompting more individuals to seek testing, thereby driving demand in the active b12-test market. Healthcare professionals are emphasizing the importance of early detection and management of deficiency-related conditions.

    Technological Advancements in Testing

    Innovations in testing methodologies are enhancing the reliability and speed of active B12 tests. These advancements are making it easier for healthcare providers to offer accurate assessments, which is likely to boost the market as more patients seek these services.

    Rise of Home Testing Solutions

    The trend towards home testing is gaining traction, as consumers increasingly prefer the convenience of managing their health from home. This shift is likely to expand the active b12-test market, as more individuals opt for at-home testing kits to monitor their vitamin B12 levels.

    US Active B12 Test Market Drivers

    Rising Geriatric Population

    The active b12-test market is poised for growth due to the increasing geriatric population in the US. As individuals age, the risk of vitamin B12 deficiency escalates, primarily due to factors such as decreased absorption and dietary changes. The US Census Bureau projects that by 2030, approximately 20% of the population will be aged 65 and older, creating a substantial market for B12 testing services. Healthcare providers are likely to focus on this demographic, emphasizing the importance of regular testing to prevent complications associated with deficiencies. This demographic shift presents a significant opportunity for the active b12-test market, as tailored testing solutions become essential for managing the health of older adults.

    Integration of Advanced Technologies

    The active b12-test market is witnessing a transformation due to the integration of advanced technologies in testing methodologies. Innovations such as high-throughput screening and automated analysis systems enhance the accuracy and efficiency of B12 testing. These technological advancements not only streamline the testing process but also reduce turnaround times, making it more convenient for healthcare providers and patients alike. The market is projected to grow as these technologies become more accessible and affordable. Additionally, the incorporation of artificial intelligence in data analysis may further improve diagnostic capabilities, allowing for more personalized healthcare solutions. As a result, the active b12-test market is likely to benefit from these advancements, attracting both healthcare professionals and patients seeking reliable testing options.

    Growing Demand for Diagnostic Testing

    The active b12-test market experiences a notable surge in demand for diagnostic testing services. This trend is driven by an increasing prevalence of vitamin B12 deficiency, which affects a significant portion of the population. According to recent data, approximately 6% of adults in the US are estimated to have low levels of vitamin B12, leading to a heightened need for effective testing solutions. As healthcare providers emphasize the importance of early detection and management of deficiencies, the active b12-test market is likely to expand. Furthermore, the rising awareness among consumers regarding the health implications of vitamin deficiencies contributes to this growing demand, prompting more individuals to seek testing services to ensure optimal health outcomes.

    Expansion of Health Insurance Coverage

    The active b12-test market is benefiting from the expansion of health insurance coverage for diagnostic tests. Recent policy changes have led to increased reimbursement rates for vitamin B12 testing, making it more accessible to a broader population. As insurance providers recognize the cost-effectiveness of early detection and treatment of deficiencies, more individuals are likely to seek testing services. This trend is particularly relevant in the context of rising healthcare costs, where preventive measures can mitigate long-term expenses. Consequently, the active b12-test market is expected to grow as insurance coverage expands, encouraging more patients to utilize testing services as part of their routine healthcare.

    Increased Focus on Preventive Healthcare

    The active b12-test market is significantly influenced by the growing emphasis on preventive healthcare measures. As individuals become more proactive about their health, there is a rising trend towards regular health screenings, including vitamin B12 testing. This shift is supported by healthcare policies that advocate for preventive care, aiming to reduce long-term healthcare costs associated with untreated deficiencies. The market is expected to expand as more healthcare providers incorporate routine B12 testing into their preventive care protocols. Furthermore, educational campaigns aimed at informing the public about the risks of vitamin deficiencies are likely to drive demand for testing services. Consequently, the active b12-test market is positioned to thrive in an environment that prioritizes preventive health strategies.

    Market Segment Insights

    By Type: Elisa Assay (Largest) vs. Enzyme Immunoassay (Fastest-Growing)

    In the US active b12-test market, the Elisa Assay segment commands a significant portion of the market share, demonstrating its established acceptance and reliability among healthcare professionals. Enzyme Immunoassay, while trailing in market share, has shown promising adoption due to its innovative technology that improves accuracy and reduces testing times, attracting a growing user base. The growth trends within this segment are driven by an increasing awareness among healthcare providers regarding the importance of accurate b12 testing. Furthermore, advancements in technology and a push for early detection of deficiencies are bolstering the Enzyme Immunoassay sector, making it the fastest-growing segment. This is indicative of a broader shift towards more precise and efficient diagnostic tools in the healthcare landscape.

    Elisa Assay (Dominant) vs. Enzyme Immunoassay (Emerging)

    The Elisa Assay segment is well-established, far surpassing its competitors in brand recognition and utilization among laboratories. Its reliability has made it the go-to choice for healthcare providers, ensuring thorough and consistent testing results. On the other hand, the Enzyme Immunoassay is emerging rapidly, driven by its sophisticated technology that allows for quicker results and better accuracy. This method appeals to modern laboratories looking for efficiency while maintaining diagnostic integrity, making it a preferred choice in settings focused on innovation and timeliness.

    By Application: Folate Deficiency Anemia (Largest) vs. Pernicious Anemia (Fastest-Growing)

    The US active b12-test market showcases a diverse application landscape, with Folate Deficiency Anemia representing the largest segment, significantly contributing to the overall market share. This segment's prominence is attributed to the increasing awareness of vitamin deficiencies and their health implications. In contrast, Pernicious Anemia is emerging as the fastest-growing segment, driven by a rise in diagnostic testing and a growing aging population that is increasingly susceptible to this condition. Growth trends in the US active b12-test market are characterized by an upward trajectory, particularly for Pernicious Anemia, as healthcare providers are prioritizing early detection and diagnosis. Factors such as improved healthcare access, advancements in diagnostic technologies, and a concerted effort to address anemia-related health issues are propelling growth across these segments. The increasing prevalence of these conditions among various demographics further highlights the need for targeted testing solutions.

    Folate Deficiency Anemia: Dominant vs. Pernicious Anemia: Emerging

    Folate Deficiency Anemia is recognized for its stable market presence, catering to a broad audience with diverse dietary needs. It primarily affects individuals with inadequate folate intake, with a strong focus on education regarding nutritional health. In contrast, Pernicious Anemia is rapidly gaining attention due to its association with intrinsic factor deficiency, making it a critical area for innovative testing strategies. This segment is positioned to capitalize on the growing demand for precise diagnostic tools. The confluence of advanced biotechnological applications and heightened public health initiatives is expected to favor both segments, bolstering their market positions as healthcare systems evolve to better address nutrient deficiency-related disorders.

    Get more detailed insights about US Active B12 Test Market

    Key Players and Competitive Insights

    The active b12-test market exhibits a dynamic competitive landscape characterized by innovation and strategic partnerships. Key players such as Thermo Fisher Scientific (US), Abbott Laboratories (US), and Roche Diagnostics (CH) are at the forefront, leveraging their technological expertise to enhance product offerings. Thermo Fisher Scientific (US) focuses on expanding its diagnostic capabilities through advanced testing solutions, while Abbott Laboratories (US) emphasizes the integration of digital health technologies to streamline testing processes. Roche Diagnostics (CH) is known for its commitment to research and development, which positions it as a leader in innovative testing methodologies. Collectively, these strategies foster a competitive environment that prioritizes technological advancement and customer-centric solutions.

    In terms of business tactics, companies are increasingly localizing manufacturing and optimizing supply chains to enhance operational efficiency. The market structure appears moderately fragmented, with several key players holding substantial market shares. This fragmentation allows for a diverse range of products and services, while the collective influence of major companies drives innovation and competitive pricing strategies.

    In October 2025, Thermo Fisher Scientific (US) announced a strategic partnership with a leading biotechnology firm to co-develop next-generation active B12 testing solutions. This collaboration is expected to enhance the accuracy and speed of testing, thereby addressing the growing demand for reliable diagnostic tools. The strategic importance of this partnership lies in its potential to solidify Thermo Fisher's position as a market leader by expanding its product portfolio and improving customer access to advanced testing technologies.

    In September 2025, Abbott Laboratories (US) launched a new digital platform aimed at integrating active B12 testing with telehealth services. This initiative is designed to facilitate remote patient monitoring and improve access to diagnostic testing. The strategic significance of this move is underscored by the increasing trend towards digital health solutions, which are likely to enhance patient engagement and streamline healthcare delivery.

    In August 2025, Roche Diagnostics (CH) unveiled a new line of active B12 test kits that utilize artificial intelligence to enhance diagnostic accuracy. This innovation reflects Roche's commitment to integrating cutting-edge technology into its product offerings. The introduction of AI-driven testing solutions is likely to set a new standard in the market, emphasizing the importance of technological advancement in maintaining competitive differentiation.

    As of November 2025, current trends in the active b12-test market are heavily influenced by digitalization, sustainability, and the integration of artificial intelligence. Strategic alliances among key players are shaping the competitive landscape, fostering innovation and enhancing product offerings. Looking ahead, it is anticipated that competitive differentiation will increasingly pivot from price-based strategies to a focus on innovation, technology, and supply chain reliability. This shift underscores the necessity for companies to adapt and evolve in response to changing market dynamics.

    Key Companies in the US Active B12 Test Market market include

    Industry Developments

    In recent months, the US Active B12 Test Market has experienced notable developments, particularly concerning advancements in diagnostic technologies and an increase in awareness about vitamin deficiencies among healthcare providers. Companies such as Mayo Clinic Laboratories and Quest Diagnostics have enhanced their testing capabilities, offering more comprehensive screening options. The market has also seen significant growth, driven by the rising prevalence of vitamin B12 deficiency, which affects a considerable portion of the US population, according to industry reports.

    In July 2023, Dynamic Health Labs announced a strategic partnership with BioReference Laboratories to expand their testing services nationwide, highlighting a trend of collaboration among leading firms in the sector.

    Moreover, Healthlynked and Everlywell have reported significant increases in consumer demand, leading to expanded testing portfolios that encompass Active B12 testing. The last few years have been transformative for the industry; in October 2021, Nutritional Testing Services reported advancements in their laboratory technologies, enhancing the accuracy of their Active B12 tests. Overall, these movements reflect an evolving market landscape, driven by both technological innovation and increasing public health awareness in the United States.

    Future Outlook

    US Active B12 Test Market Future Outlook

    The active b12-test market is projected to grow at a 4.41% CAGR from 2024 to 2035, driven by increasing health awareness and advancements in diagnostic technologies.

    New opportunities lie in:

    • Development of mobile testing units for remote patient access.
    • Partnerships with healthcare providers for integrated testing solutions.
    • Expansion of online platforms for direct-to-consumer testing services.

    By 2035, the market is expected to achieve robust growth, reflecting evolving healthcare demands.

    Market Segmentation

    US Active B12 Test Market Type Outlook

    • Elisa Assay
    • Enzyme Immunoassay
    • Others

    US Active B12 Test Market Application Outlook

    • Folate Deficiency Anemia
    • Pernicious Anemia
    • Macrocytic Anemia
    • Others

    Report Scope

    MARKET SIZE 2024 0.974(USD Million)
    MARKET SIZE 2025 1.02(USD Million)
    MARKET SIZE 2035 1.57(USD Million)
    COMPOUND ANNUAL GROWTH RATE (CAGR) 4.41% (2024 - 2035)
    REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    BASE YEAR 2024
    Market Forecast Period 2025 - 2035
    Historical Data 2019 - 2024
    Market Forecast Units USD Million
    Key Companies Profiled Thermo Fisher Scientific (US), Roche Diagnostics (CH), Abbott Laboratories (US), Siemens Healthineers (DE), Danaher Corporation (US), Bio-Rad Laboratories (US), Ortho Clinical Diagnostics (US), PerkinElmer (US)
    Segments Covered Type, Application
    Key Market Opportunities Growing demand for personalized health diagnostics drives innovation in the active b12-test market.
    Key Market Dynamics Rising consumer awareness drives demand for active B12 testing, influencing market competition and innovation.
    Countries Covered US

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    FAQs

    What is the estimated market size of the US Active B12 Test Market in 2024?

    The estimated market size of the US Active B12 Test Market in 2024 is 975.1 million USD.

    How much is the US Active B12 Test Market expected to grow by 2035?

    By 2035, the US Active B12 Test Market is expected to reach a value of 6014.0 million USD.

    What is the expected CAGR for the US Active B12 Test Market from 2025 to 2035?

    The expected CAGR for the US Active B12 Test Market from 2025 to 2035 is 17.985%.

    Which segment of the market is leading in terms of value in 2024?

    In 2024, the Enzyme Immunoassay segment is leading with a market value of 450.0 million USD.

    What revenue is predicted for the Elisa Assay segment by 2035?

    The Elisa Assay segment is predicted to generate a revenue of 2100.0 million USD by 2035.

    Who are the major players in the US Active B12 Test Market?

    Major players in the market include Mayo Clinic Laboratories, Quest Diagnostics, and Labcorp, among others.

    What are the expected revenue figures for the Other type segment in 2024 and 2035?

    The Other type segment is valued at 175.1 million USD in 2024 and is expected to reach 1214.0 million USD by 2035.

    Is there a significant market trend in the US Active B12 Test Market?

    One significant trend in this market is the increasing demand for efficient diagnostic tests, including those for B12 levels.

    What growth opportunities exist for the US Active B12 Test Market?

    Growth opportunities exist due to an increasing awareness of B12 deficiency and advancements in testing technologies.

    How does the competitive structure of the US Active B12 Test Market look?

    The competitive structure features numerous established laboratories and diagnostic services competing for market share.

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