The market trends in Type 2 Diabetes Mellitus (T2DM) treatment reflect a dynamic landscape shaped by improvements in medical research, technological innovations and changes in regulations on healthcare. In the recent past, there has been a paradigm shift of health care systems to be more personalized. Consequently, this has led to the invention of novel ways of treating diseases with focus on individual cases. Pharmaceutical firms are investing heavily on R&D for new medications that would efficiently control blood glucose levels as well as improve therapeutic outcomes.
Increasing adoption oral antidiabetic drugs is one trend that can be seen. This is because patients and doctors want easier modes of treatment; hence they opt for oral medicines that are easy to administer and have higher adherence rates as compared to other forms such as injections and implants. The change has resulted in the discovery of better generation oral agents with improved efficacy and reduced side effects thereby amplifying the size of T2DM treatment market
Additionally, digital health solutions have been integrated into T2DM management. For example use mobile apps, wearable devices and remote monitoring tools among others are used as part of patient’s treatment plan to help collect real time data which helps doctors monitor their patients’ conditions quickly and easily while they remain anywhere else in globe.. These measures foster self sufficiency among patients leading to empowerment even at personal level improving individual self-care from time to time according one’s own body sugar levels . As far as technology-driven software goes, there are several solutions intended not only for patients but also related stakeholders; all aimed at optimising therapy outcome.
Another notable trend is combination therapies becoming more prominent. Since T2DM is multi-factorial various pharmaceuticals develop compound drugs targeting many pathways linked with glucose regulation Biologically active components commonly occur concomitantly leading to additive or multiplier effects often associated with synergy thus enabling better glucose control yet lowering adverse events.. Combination therapies have been developed to make it easier for patients to adhere to their treatment regimens.
Biosimilar drugs have also emerged as a noteworthy trend in the T2DM treatment market. The patents of some biologic drugs expired causing the introduction of biosimilars into the market. This allows cheaper options for treating this condition thus increasing patient population because majority may not be able to afford other expensive medications or therapeutic approaches associated with diabetes. An increased availability of biosimilars would contribute significantly to an expanded T2D market and its competitiveness.
These global trends are influenced by demographic shifts and rising prevalence of T2DM. As populations age and lifestyles undergo changes, the incidence of diabetes continues to rise, creating a sustained demand for innovative treatment options. On the other hand, emerging economies such as India and China have become significant contributors to market growth due to increased healthcare expenditure and awareness about diabetes management."
Type 2 Diabetes Mellitus Treatment Market Size was valued at USD 18.53 Billion in 2023. The Global Type 2 Diabetes Mellitus Treatment industry is projected to grow from USD 18.86 Billion in 2024 to USD 39.18 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.45% during the forecast period (2024 - 2032).
Type 2 diabetes mellitus is a metabolic disorder which results from an excess of caloric intake over energy expenditure. The condition is characterized by progressive insulin secretory defect, which increases the body’s demand for insulin in order to retain glucose homeostasis. Hyperglycemia is a major symptom of type 2 diabetes mellitus. According to the National Diabetes Statistics Report suggested by CDC, it is found that 9.4% of the U.S. population, i.e. 30.3 million people had diabetes in 2015.
It is noted that rising technological advancements and escalating prevalence are the key factors driving the type 2 diabetes mellitus treatment market. With the rising awareness about the condition, market players are coming up with novel drugs and devices owing to technological advancements. For instance, in December 2017, Novo Nordisk received FDA approval for Ozempic (semaglutide). The drug was specially designed for the treatment of type 2 diabetes mellitus. In the same year, Merck has also received FDA approval for Steglatro (ertugliflozin).
Various other factors such as growing awareness, huge research funding in diabetes diagnosis and treatment, unmet medical needs, increasing global prevalence of obesity, improving regulatory framework, increasing government assistance, and increasing adoption rate, are continuously contributing to the growth of the global type 2 diabetes mellitus treatment market.
Despite these drivers, there are some issues associated with type 2 diabetes mellitus treatment market. The high cost associated with diagnosis and treatment of diabetes, side effects of available treatment options, and poor healthcare system in low and middle-income countries may hamper the growth of the market to an extent.
A chronic condition that affects the body's blood sugar level is type 2 diabetes (T2D). The cardiovascular system, blood vessels, kidneys, eyes, and nerves suffer negative effects from hyperglycemia or elevated blood sugar levels. The market for diabetes treatments has been paved for expansion by the rising prevalence of the disease and advancements in novel diabetes therapies, which have considerably improved the market's design and functioning. A metabolic disease called type 2 diabetes mellitus is brought on by a calorie surplus compared to energy expenditure. The increasing insulin secretory failure that characterizes the syndrome raises the body's need for insulin to maintain glucose homeostasis. One of the main signs of type 2 diabetes mellitus is hyperglycemia. The diabetes therapy market has been growing steadily due to several factors.
First, the market has been driven by an increase in healthcare spending. Additionally, the market for diabetic treatments is impacted by the growing elderly population. The need for diabetic therapies has been fueled by growing awareness of diabetes and its effects. Early diagnosis, improved management techniques, and a rise in demand for efficient treatment alternatives have all been made possible by education campaigns and efforts launched by medical organizations, governments, and advocacy for patients' organizations.
Governments worldwide are implementing plans to fight diabetes and its associated issues. Campaigns to raise awareness, early screening applications, reimbursement rules, and financial incentives to create and adopt novel therapies are just a few of these activities. The increase in the prevalence of type 2 diabetes (T2D) disease worldwide is the main reason driving the growth of the T2D market globally.
The market for products, drugs, equipment, and treatments used for managing and treating diabetes is a worldwide diabetes treatment market. Due to the body's inability to efficiently generate or use the hormone insulin, which controls blood glucose levels, diabetes is a persistent medical illness marked by excessive blood sugar levels. However, the market expansion is constrained by patients' lack of knowledge about the accessible nature of such treatments. On the other hand, unmet medical demands in developing nations are anticipated to offer profitable market expansion potential.
The US Food and Drug Administration has authorized Bexagliflozin (Brenzavvy, TheracosBio) to receive treatment for adult patients with type 2 diabetes. For people with type 2 diabetes, but not those with type 1 diabetes, the once-daily 20-mg oral sodium-glucose cotransporter 2 (SGLT2) inhibitor is suggested as an addition to diet and exercise to enhance glycemic control. Adults having a glomerular filtration rate that has been estimated can utilize it. Bexagliflozin, either as a monotherapy or as an addition to metformin and other glucose-lowering medications and combinations, significantly decreased A1c and fasting blood glucose at twenty-four weeks in the phase 3 studies. Additionally, it led to moderate drops in systolic blood pressure and body weight.
The global type 2 diabetes mellitus treatment market is segmented on the basis of treatment and end user.
On the basis of the treatment, the market is classified as a drug class and devices. The drug class is further segmented into insulin, sensitizers, SGLT-2 inhibitors, alpha-glucosidase inhibitors, secretagogues, peptide analogs, others.
The sub-segment of sensitizers includes thiazolidinediones and biguanides. The sub-segment of secretagogues includes sulfonylureas and non-sulfonylureas. The devices market is further segmented into blood glucose monitoring devices and insulin delivery devices.
The sub-segment of blood glucose monitoring devices includes testing strips, lancets, continuous glucose monitors, self-monitoring blood glucose meters, and others. The sub-segment of insulin delivery devices includes insulin pens, insulin pumps, insulin syringes, and insulin jet injectors.
On the basis of the end user, the market is segmented into hospitals, clinics, diagnostic centers, drug stores, pharmacies, and others.
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The treatment of type 2 diabetes in children 10 years of age and older has been approved by the US Food and Drug Administration for both empagliflozin (Jardiance, Boehringer Ingelheim) or empagliflozin coupled with metformin (Synjardy, BI). After metformin, which seems less successful for youngsters than adults, its approval offers an additional oral treatment choice for kids and teens with type 2 diabetes. For children with type 2 diabetes, injectable glucagon-like peptide-1 (GLP-1) agonists are also available. These include once-weekly extended-release exenatide (Bydureon/Bydureon BCise) and daily liraglutide (Victoza).
The Americas dominate the type 2 diabetes mellitus treatment market owing to the presence of patient population, a well-developed technology, high healthcare expenditure, and the presence of the leading players. Due to the rising prevalence of diabetes, various companies, and government associations are actively participating in improving diabetes care. For instance, The Merck Foundation has provided funding of around USD 10,000,000 for the projects designed to improve diabetes care in the United States.
Europe holds the second position in the type 2 diabetes mellitus treatment market. It is expected that the government support towards research & development expenditure and amendments in reimbursement policies in the healthcare is likely to drive the European market. As per the German maternity guidelines, every pregnant woman can undergo glucose challenge test for the early diagnosis of Gestational diabetes mellitus, and the charges for the test are completely covered by women’s health insurance.
Asia Pacific is the fastest growing type 2 diabetes mellitus treatment market owing to a huge patient pool, increasing demand, and development in healthcare technology.
The Middle East & Africa holds the lowest share of the global market due to low development, lack of technical knowledge, and poor medical facilities.
Some of key the players in the global type 2 diabetes mellitus treatment market are:
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