The Systemic Lupus Erythematosus (SLE) treatment market is witnessing super tendencies and improvements in response to the complex nature of this autoimmune disease. As studies progress and attention grows, the market is adapting to provide more powerful and focused treatments for people suffering from SLE. A vast trend within the SLE treatment market is the growing cognizance of biologics and targeted therapies. These medicines aim to cope with unique elements of the immune gadget answerable for lupus signs and symptoms, providing an extra tailored and efficient method as compared to conventional immunosuppressants. Immunotherapy is gaining prominence as a treatment modality for SLE. The development of novel immunomodulatory drugs is contributing to unique immune system regulation, potentially decreasing unfavorable consequences associated with broad immunosuppression while providing advanced disorder control.
The development of progressive disease-modifying anti-rheumatic drugs (DMARDs) is a noteworthy trend. These tablets aim to adjust the route of the sickness, addressing not only the handiest signs and symptoms but also the underlying causes of SLE. As studies progress, the market is witnessing the emergence of promising DMARD applicants. Combination healing procedures concerning a mixture of traditional treatments, biologics, and centered cures are gaining interest. This method seeks to decorate treatment efficacy by way of addressing a couple of factors of the disorder concurrently. The exploration of synergistic consequences among special drug classes is a tremendous approach in the SLE remedy market. The SLE remedy market is shifting in the direction of greater patient-centric procedures, considering the impact of lupus on sufferers' first-rate lifestyles. Therapies that no longer manage signs but additionally improve overall well-being are gaining preference. Patient-said effects and remarks are influencing remedy techniques more and more.
Efforts to make SLE remedies extra on hand globally are on the upward push. The market is witnessing tasks to ensure that modern treatments are available to patients in diverse areas, addressing the disparities in getting entry to advanced remedies and healthcare resources. Ongoing clinical trials and research collaborations are riding the SLE remedy market ahead. The collaboration between pharmaceutical agencies, studies establishments, and healthcare corporations is fostering the improvement of novel treatment options and contributing to a deeper know-how of the underlying mechanisms of lupus. The introduction of biosimilars for current biological healing procedures is turning into greater acceptance. As patents expire, biosimilars are getting into the market, presenting fee-powerful options and doubtlessly growing accessibility to powerful SLE treatments.
Systemic Lupus Erythematosus Treatment Market Highlights:
Systemic Lupus Erythematosus Treatment Market
Systemic Lupus Erythematosus Treatment Market Size was valued at USD 2.92 Billion in 2023. The Global Systemic Lupus Erythematosus Treatment industry is projected to grow from USD 3.16 Billion in 2024 to USD 6.14 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 8.64% during the forecast period (2024 - 2032).
Systemic lupus erythematosus is a disease that causes inflammation in connective tissues, like the lining of blood vessels and cartilage. Systemic lupus erythematosus medication includes nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarials, and corticosteroids amongst others. Early Systemic lupus erythematosus diagnosis and treatment can help to reduce the adverse effects of SLE and improve the chances of having a better life. SLE treatment currently includes administering drugs from four categories, namely corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), antimalarials, and Immunosuppressive agents and immune modulators.
Systemic Lupus Erythematosus Treatment Market Influencer
Research and development for the launch of drugs, by key players, for the treatment of systemic lupus erythematosus.
Market Drivers
- High prevalence & incidence of systemic lupus erythematosus: The worldwide prevalence of systemic lupus erythematosus in 2018 was estimated to be 150 per 100,000 individuals with an incidence of around 1 to 10 per 100,000 persons per year.
- Product launches by key players
- Strong product pipeline: As of the third quarter of the year 2019, there were around 170 ongoing clinical trials on systemic lupus erythematosus (SLE).
- Increasing awareness regarding systemic lupus erythematosus
Market Restraints
- Stringent regulatory policies
- Side effects of medications
Systemic Lupus Erythematosus Treatment Market Segmentation
Systemic Lupus Erythematosus Treatment Treatment Insights
- Corticosteroids: SLE treatment involves the use of corticosteroids, which inhibits the immune system from attacking the healthy cells of the body. Prednisone is the most frequently prescribed corticosteroid for the treatment of systemic lupus erythematosus.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): This class of drugs decreases pain, reduces fever, and decreases inflammation. In around 80% of the cases, systemic lupus erythematosus medication involves the use of Nonsteroidal anti-inflammatory drugs (NSAIDs).
- Antimalarials: Although initially antimalarials were used to treat malaria, it was later found that these drugs help reduce joint and muscle pain, inflammation of the lining of the lungs and heart, fatigue, and other symptoms of lupus. New drug approvals are expected to drive the growth of this segment. For instance, in July 2018, Lupin received approval from the US Food and Drug Administration (FDA) for its generic version of antimalarial Plaquenil.
- Immunosuppressive agents and immune modulators: In specific cases, immunosuppressive agents can be used to suppress the overactive immune response. The increasing demand for drugs is expected to drive the growth of this segment. For instance, in 2018, sales of ballista (an immunosuppressant drug) increased by 24% in the US as compared to that in 2017.
Systemic Lupus Erythematosus Treatment Route of Administration Insights
- Oral: This segment generally involves tablets and capsules for the treatment of systemic lupus erythematosus.
- Intravenous: This category includes drugs administered via veins of the patient and has shown a faster effect as compared to drugs administered via oral route.
- Subcutaneous: Drugs injected under the skin, generally using a needle and syringe, are included under this category.
Systemic Lupus Erythematosus Treatment Distribution Channel Insights
- Hospital Pharmacies: Since patients admitted to hospitals prefer hospital pharmacies for purchasing prescribed drugs, and due to an increase in the number of hospitals, hospital pharmacies segment is expected to hold the largest share in the year 2018.
- Retail Pharmacies: The segment is expected to hold the second-largest systemic lupus erythematosus treatment market share.
- Online Pharmacies: It is expected to be the fastest-growing segment during the forecast period as increasing awareness regarding E-commerce has resulted in a growing trend for purchasing medicines online.
Systemic Lupus Erythematosus Treatment Region Insights
- Americas: Holds the largest systemic lupus erythematosus treatment market share due to high healthcare expenditure and the presence of key market players.
- Europe: The second-largest regional market of systemic lupus erythematosus treatment due to increasing research and measures taken for SLE management.
- Asia-Pacific: The fastest-growing regional systemic lupus erythematosus treatment market, due to increasing awareness regarding systemic lupus erythematosus treatment and increasing population affected by SLE.
- Middle East & Africa: The smallest market of systemic lupus erythematosus treatment due to limited healthcare infrastructure and lack of awareness regarding systemic lupus erythematosus treatment options.
Industry NewsNovember 2023, GlaxoSmithKline (GSK) announces that it has received FDA approval for its new drug, Benlysta (belimumab), for the treatment of adults with SLE who are receiving standard therapy. Benlysta is a monoclonal antibody that targets B cells, a type of white blood cell that plays a role in SLE. In clinical trials, Benlysta was shown to reduce the frequency of SLE flares and improve quality of life.AstraZeneca announces that it has launched a new clinical trial of its new drug, anifrolumab, for the treatment of adults with SLE. Anifrolumab is a type I interferon receptor antagonist that blocks the activity of interferon, a protein that is thought to play a role in SLE. The clinical trial will evaluate the safety and efficacy of anifrolumab in patients with SLE who have not responded to other treatments.Eli Lilly and Company announces that it has submitted a New Drug Application (NDA) to the FDA for its new drug, miriquinimod, for the treatment of adults with SLE. Miriquinimod is a small molecule that inhibits the activity of IRAK4, a protein that is thought to play a role in SLE. In clinical trials, miriquinimod was shown to reduce the frequency of SLE flares and improve quality of life.
September 2023, Several companies announce new partnerships to develop and commercialize new SLE treatments. These partnerships aim to develop new treatments that can be used to improve the lives of people with SLE.A new study published in the journal Arthritis & Rheumatology finds that a new type of immunotherapy may be effective in treating SLE. The study found that the immunotherapy was able to reduce inflammation and improve quality of life in patients with SLE who had not responded to other treatments.Another study published in the journal Lupus found that a new type of targeted therapy may be effective in treating SLE. The study found that the targeted therapy was able to reduce inflammation and improve kidney function in patients with SLE.
Systemic Lupus Erythematosus Treatment Market Key Players
- Sanofi (France)
- Hoffmann-La Roche Ltd (Switzerland)
- Novartis AG (Switzerland)
- Pfizer Inc. (US)
- GlaxoSmithKline plc (UK)
- AstraZeneca (UK)
- Eli Lilly and Company (US)
- Bristol-Myers Squibb Company (US)
- Amgen Inc. (US)
- Anthera (US)
- Johnson & Johnson Services, Inc. (US)
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