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Renal Denervation Market Size

ID: MRFR//5249-HCR | 115 Pages | Author: Kinjoll Dey| December 2024

The market for renal denervation is influenced by various factors that collectively shape its dynamics. Renal denervation is a medical procedure designed to treat hypertension by disrupting nerve signals to the kidneys. One key market factor is the rising prevalence of hypertension worldwide. With hypertension constituting a global health dilemma, attention should be focused on developing strategies that will prove efficient in lowering blood pressure, such as renal denervation. Further, the rising knowledge among hypertension patients and health cleans which point to the prospects of renal denervation have contributed to market growth.

The two key drivers that help determine the future of the renal denervation business are the governmental projects and healthcare regulations. The universal acceptance of renal denervation treatments can be influenced greatly by the availability of supporting regulations and by the policies that relate to reimbursements. Along with well-placed policies that may promote clear and cost-effective solutions in the treatment of chronic illnesses, the renal denervation market is well-positioned to garner much favor from governments that encourage its comprehensive use for hypertension management.

Another major market factor of renal denervation technology shift is the technological advancements that have shaped the renal denervation market. Progress in the field of minimally invasive techniques as well as revamped technologies for arterial denervation methods leads to better and, therefore, more widely integrated approaches to treatment of cardiovascular disease. Technology progress also plays a key role in renal denervation evolution through advancing safety and effectiveness of the therapy, which makes it more profitable for both healthcare professionals and patients.

Renal denervation market growth opportunities are often created in collaborative and strategic partnership between healthcare industry. The team work between the medical equipment manufacturing enterprises, the pharmaceutical organizations and the healthcare organizations offers an environment, where research and development endeavors can be conducted leading to the output of new techniques and treatment approaches. These cooperative agreements can bring benefits to the market size of renal denervation technologies, ultimately emerged to more accessible and adopted worldwide.

These, in turn, create the conditions for movement of the markets. Cruel is that the ageing population is more prone to hypertension thus creating the market for useful approaches like renal denervation in developed regions. Given that the growth of global population along with the increases in the occurrence of hypertension are unavoidable, the innovations in the renal denervation market will only be seen more in the future.

Covered Aspects:

Report Attribute/Metric Details
Market Size Value In 2022 USD 0.8 Billion
Market Size Value In 2023 USD 1.11 Billion
Growth Rate 38.60% (2023-2032)

Global Renal Denervation Market Overview


The Renal Denervation Market Size was valued at USD 1.11 Billion in 2023 and is projected to grow from USD 1.53 Billion in 2024 to USD 15.09 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 33.03% during the forecast period (2024 - 2032).The increasing spread of hypertension and the rise in clinical studies are market drivers expediting the market’s expansion.


Renal Denervation Market


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


Renal Denervation Market Trends



  • Rising cases of hypertension across people are driving the market growth


The rise in the spread of chronic diseases and the growing spread of hypertension is driving Market CAGR for renal denervation. One of the key drivers of market growth is the increase in occurrences of therapy-resistant hypertension. One of the most prevalent diseases in the world is hypertension. More than 360,000 Americans died in 2013 as a result of high blood pressure, according to the Centers for Disease Control and Prevention (CDC). From 17,307 per 100,000 people in 1990 to 20,525 per 100,000 people in 2015, hypertension has increased. However, renal denervation therapy has successfully decreased blood pressure. The benefits of these therapies, such as their persistent effects, shorter treatment times, and improved safety levels, are thereby promoting market expansion. The development of renal denervation devices is also anticipated to fuel market growth.


As an illustration, the development of catheter-based interventional therapy to ablate the renal nerve has demonstrated excellent benefits in the management of blood pressure in patients presenting with complaints of resistant hypertension. Additionally, the catheter-based approach facilitates the denervation of particular nerves and seems to be safer for patients.


The amount of alcohol sold in 15 US states increased by 4% from January to August 2020 compared to a year earlier, as per the National Institute on Alcohol Abuse and Alcoholism. This could increase the risk of hypertension and encourage the use of renal denervation devices. Consequently, it is projected that the studied market would expand over the coming years as a result of factors such as an increase in product sales, the introduction of new products, and an increase in health problems connected to hypertension.


Growth in the market is also predicted to be fueled by an increase in clinical studies, research, and development related to renal denervation devices, as well as the long-term advantages of renal denervation treatments. For instance, according to research that appeared in April 2022 issue of the journal Nature, more than 80% of Thai patients with resistant hypertension benefited from the effectiveness of renal nerve denervation, which was maintained over a longer follow-up period without any intervention-related side effects.


It is also projected that the development of the healthcare infrastructure in emerging economies and the availability of substitutes and better technology, such as micro-infusion for renal denervation systems, will accelerate market expansion. For instance, the renal denervation system is based on micro-infusion from Mercator MedSystem. It distributes substances at a specified location to denervate the renal artery, lowering the patient’s blood pressure. Thus, driving the Renal Denervation Market revenue.


Renal Denervation Market Segment Insights


Renal Denervation Product Insights


The Market segments of Renal Denervation, based on product includes Simplicity, Vessix (V2), EnligHTN, Paradise, Iberis, and Others. The biggest market share for renal denervation was simplicity. Due to its delivery of low-level radiofrequency energy and consequent reduction in the risk of radiation exposure to body tissues from high-level radiofrequency, this system is most frequently employed to treat hypertension. Additionally, it provides a minimally intrusive method for treating severe hypertension.


Renal Denervation Technology Insights


The Renal Denervation Market segmentation, based on technology, includes Radiofrequency, Ultrasound, Micro-infusion, and Others. Due to its benefits, including safety and time efficiency, the radiofrequency category had the biggest market share. As ultrasound devices get around the restrictions of radiofrequency-based systems, the segment is expected to grow at the highest CAGR. The nerves are destroyed by ultrasound energy using high-frequency sound waves without making direct contact with the tissues, which lessens damage to the renal arteries.


Renal Denervation End-User Insights


The Market segmentation of Renal Denervation, based on end-user, includes hospitals, Clinics, Ambulatory surgery centers, and Others. Due to the rising demand for renal denervation, the hospitals segment dominates the end-user section of the worldwide renal denervation market.


Figure 1: Renal Denervation Market, by End-User, 2022 & 2032 (USD Billion) 


Renal Denervation Market, by End-User, 2022 & 2032


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


Renal Denervation Regional Insights


By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. Due to the increasing number of requests for FDA approvals in the U.S., North America is expected to dominate the market. As an illustration, the FDA has permitted Medtronic to begin a key Investigational Device Exemption (IDE) trial to test the Symplicity Spyral renal denervation system in patients with hypertension.


Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2: RENAL DENERVATION MARKET SHARE BY REGION 2022 (USD Billion) 


RENAL DENERVATION MARKET SHARE BY REGION 2022


Source: Secondary Research, Primary Research, MRFR Database, and Analyst Review


Europe’s Renal Denervation Market accounts for the second-largest position in the market. This is a result of increased R&D efforts for the creation of effective devices. The prevalence of drug-resistant hypertension will also rise, fueling the area's expansion. Further, the UK market of Renal Denervation held the largest market share, and the Germany market of Renal Denervation was the quickest-growing market in the North American region


The Asia-Pacific Renal Denervation Market is anticipated to expand at the quickest CAGR. This is due to the abundance of unmet medical needs for the treatment of hypertension, growing knowledge of the utilization of cutting-edge technology such as renal denervation systems, and the high prevalence of resistant hypertension. Moreover, China market of Renal Denervation held the fastest CAGR, and the India market of Renal Denervation was the quickest-growing market in the Asia-Pacific region.


Renal Denervation Key Market Players & Competitive Insights


Leading market players are investing largely in research & development-related activities to extend their product/service lines, which will aid the market of Renal Denervation, to grow faster. Market leaders are also adopting a range of strategies to expand their worldwide position, with important market developments including new product launches & developments, contractual agreements among companies with complementary service lines, mergers & acquisitions, increased investments, & collaboration with other organizations having complementary products and services. To grow in a competitive and rising market climate, the Renal Denervation industry needs to offer cost-efficient products.


Producing locally to cut operational expenses is one of the prime business strategies used by manufacturers in the Renal Denervation industry to benefit clients and increase the market sector. In recent years, the Renal Denervation industry has served with some of the key perks of medicine. Major players in the Renal Denervation Market, including Boston Scientific, Medtronic, ReCor Medical, St. Jude Medical, Cardiotonic, Cordis, Kona Medical, Sound Intervention, Terumo, and others are attempting to increase market growth via investing in research and development operations.


ReCor Medical is a manufacturer of medical equipment and a leader in the development of Ultrasound Renal Denervation (ADN) technology for the management of hypertension, one of the most common medical disorders. ReCor Medical creates and produces the Paradise Ultrasound Renal Denervation system, which uses ultrasound energy to treat overactive renal nerves during a single minimally invasive operation to control high blood pressure. Only exploratory use of the Paradise System is permitted within the United States. only for distribution in nations with CE certification. ReCor Medical Inc. is the owner of the trademark The Paradise System. In February 2023, According to a study, the Paradise ultrasonic renal denervation (uRDN) device from ReCor Medical successfully lowered blood pressure. The Radiance clinical trial findings are significant because they confirm the Paradise uRDN System's usefulness as a supplementary therapy for the treatment of hypertension.


Designing, developing, producing, and marketing medical devices and solutions are the core competencies of Medtronic Plc (Medtronic), formerly known as Medtronic Inc. It provides goods for the treatment of conditions such as diseases of the heart valves, heart failure, peripheral vascular, venous renal, and neurological diseases, spine and musculoskeletal disorders, and ear, nose, and throat conditions. It also provides goods for the treatment of aortic, coronary, peripheral, and peripheral vascular diseases. For the dentistry and orthopedic businesses, it also offers biologic solutions. In the regions of Asia Pacific, Europe, the Americas, the Middle East, and Africa, it offers its products to hospitals, third-party healthcare providers, clinics, institutions, and government healthcare programs. Dublin, Ireland serves as the company's headquarters. In September 2022, According to trial results released by Medtronic, the Symplicity renal denervation device significantly lowers blood pressure. The radiofrequency renal denervation (RF RDN) procedure was performed on individuals in the SYMPLICITY HTN-3 clinical trial using first-generation Symplicity. Results showed that when compared to a sham control group, office, and ambulatory blood pressure decreased statistically significantly.


Key Companies in the Renal Denervation Market include





  • ReCor Medical




  • St. Jude Medical




  • Cardiosonic




  • Cordis



  • Medtronic




  • Kona Medical




  • Sound Intervention




  • Terumo




Renal Denervation Industry Developments


July 2023:The new European Hypertension Society (ESH) recommendations, which emphasize the importance of renal denervation (RDN) as a component of the hypertension therapy pathway, are very exciting to Medtronic. The recommendations were released concurrently in the Journal of Hypertension and during the ESH 32nd Annual Meeting.


Renal Denervation Market Segmentation


Renal Denervation, Product Outlook (USD Billion, 2018-2032)




  • Simplicity




  • Vessix (V2)




  • EnligHTN




  • Paradise




  • Iberis




  • Others




Renal Denervation, Technology Outlook (USD Billion, 2018-2032)




  • Radiofrequency




  • Ultrasound




  • Micro-infusion




  • Others




Renal Denervation, End-users Outlook (USD Billion, 2018-2032)




  • Hospital




  • Clinics




  • Ambulatory surgery centers




  • Others




Renal Denervation Regional Outlook




  • North America








    • US




    • Canada








  • Europe








    • Germany




    • France




    • UK




    • Italy




    • Spain




    • Rest of Europe








  • Asia-Pacific




    • China




    • Japan




    • India




    • Australia




    • South Korea




    • Australia




    • Rest of Asia-Pacific






  • Rest of the World




    • Middle East




    • Africa




    • Latin America





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