Protein Engineering Market Analysis

Protein Engineering Market Overview

The Protein Engineering Market Size was valued at USD 1.5 Billion in 2022 and is projected to grow from USD 1.7 Billion in 2023 to USD 4.09 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 11.80% during the forecast period (2023 - 2032). Chronic diseases are becoming more prevalent, and synthetic biology is receiving more funding, which are the key market drivers enhancing market growth.

Source Secondary Research, Primary Research, MRFR Database, and Analyst Review

In June 2024, Daicel Arbor Biosciences is pleased to announce the launch of the latest version of their myTXTL® kits. These kits are used for cell-free protein production and are specifically designed to streamline and expedite the process of discovering antibodies and designing proteins. The myTXTL Pro Kit and the myTXTL Antibody/DS Kit are advanced kits that offer researchers versatile tools to increase the efficiency of their protein expression platforms. 

These kits are designed to elevate the performance of discovery programs in both industry and academia. The myTXTL Pro Kit provides researchers with a very efficient method for expressing proteins that do not include disulfide bonds. It consolidates all the advantages of our prior kit options into a single package, making it a more convenient and reliable alternative. The Pro Kit is versatile and can be used for several applications in protein expression and synthetic biology, such as doing a basic library screen, performing CRISPR-Cas activity experiments, or testing gene circuits.

In June 2024, Brevel, Ltd., a company specializing in microalgae protein, inaugurated its inaugural commercial facility. The new facility spans an area of 27,000 square feet (equivalent to 2,500 square meters) and has the capability to manufacture hundreds of tons of microalgae protein powder. Situated on the outskirts of Israel's desert, the new facility is designed to expedite the entry of Brevel's novel plant protein into the commercial food industry by scaling up production to industrial levels. 

Brevel claims that it can offer a novel protein supply derived from specially cultivated microalgae of the chlorella genus, using its newly established facilities. The final ingredient is said to be extremely healthy, containing a complete amino acid profile while also being cost-effective. The state-of-the-art facility includes cutting-edge bioproduction laboratories, expansive workspaces, a contemporary food application laboratory, and state-of-the-art quality control technology. 

Protein Engineering Market Trends

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  Increasing demand for treatments and medications based on proteins drives market growth

  
  

Market CAGR for protein engineering is being driven by the rising need for treatments and medications based on proteins over the forecast period, and market for protein engineering, which is extremely dependent on the rising need for proteins made from proteins. Biologics, or proteins-based medications, treat various illnesses like cancer, autoimmune conditions, and uncommon genetic disorders. Drugs based on proteins have several benefits over conventional small-molecule medications. As they are created to interact with particular targets in the body, they are frequently more selective and have fewer adverse effects.

Additionally, protein-based medications have a lower likelihood of being metabolized by the liver, which can increase their effectiveness and lower the possibility of toxicity. These benefits have led to a huge increase in the demand for protein-based medicines on the international market. Many variables, such as the rising prevalence of chronic diseases, aging populations, and rising healthcare costs, influence this rise. The desire for new and improved therapeutics is mostly driven by the increased prevalence of chronic diseases like cancer, diabetes, and cardiovascular problems.

In addition, it is projected that the market would grow significantly as a result of the rising number of government programmes meant to advance the field of protein engineering. As a result, there has been a growth in this field's R&D spending, amount of funds awarded, and research and development programs. For instance, Nabla Bio reported that a USD 11 million seed fundraising round would be completed in December 2021. With the aid of this funding, a platform for AI-first design will be created, paving the way for new antibody therapies.

Likewise, Generate Biomedicines, and Amgen confirmed A research partnership agreement to create protein therapeutics for 5 clinical targets in January 2022. The demand for protein engineering is being driven by the rise in chronic & lifestyle diseases like diabetes, cardiovascular disorders, and others. As a result, it is anticipated that the demand for protein engineering will increase throughout the projection period due to the high demand for treatments and medications. Thus, driving the protein engineering market revenue.

Protein Engineering Market Segment Insights

Protein Engineering Type Insights

The market segments of protein engineering, based on type, includes instruments, reagents, and services & software. The instrumentS segment dominated the market, accounting for 51.50% of market revenue (0.77 Billion). Demand for this market segment is being driven by the growing preference among researchers for automated methods for encouraging quick molecular development processes.

Protein Engineering Application Insights

The protein engineering market segmentation, based on application, includes food & detergent Industries, environment, medical, biopolymer production, and nanobiotechnology. The nanobiotechnology category generated the most income (35%). This is due to the widespread use of hybrid techniques, which combine directed evolution and rational design, for various purposes, such as improving redox proteins and enzymes. The fabrication of nano-devices for biosensing and other significant nanotechnology engineering applications places a high value on these enzymes, boosting the chances for future growth.

Protein Engineering Route Administration Insights

The market segmentation of protein engineering, based on method, includes rational protein design and directed evolution. The rational protein design segment dominated the market, accounting for 58% of market revenue. The technology's vast application in enzyme engineering and antibody development accounts for the dominant share. Enzyme engineering has seen a tremendous increase in its commercial uses, which has led to the creation of improved and modified enzymes with the appropriate catalytic capabilities.

Protein Engineering End User Insights

The  protein engineering market segmentation, based on end-users, includes pharmaceuticals & biotechnology companies, contract engineering organizations, and academic research institutes. The pharmaceuticals & biotechnology companies segment dominated the market, accounting for 52% of market revenue. The segment is expanding due to more and more in silico drug discovery models being used to treat neurological issues, cancer, and diabetes. These companies continuously attempt to preserve their market position by creating drug versions of patent-expiring pharmaceuticals utilizing a computer modeling technique.

Figure 1  Protein Engineering Market by End User, 2022 & 2032 (USD Billion)

Source Secondary Research, Primary Research, MRFR Database, and Analyst Review

Protein Engineering Regional Insights

By region, the study provides market insights into North America, Europe, Asia-Pacific, and the Rest of the World. The North American protein engineering market will dominate this market, owing to the presence of numerous market players and their varied strategic efforts.

Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure 2  Protein Engineering Market Share By Region 2022 (USD Billion)

Source Secondary Research, Primary Research, MRFR Database, and Analyst Review

Europe's Protein Engineering market accounts for the second-largest market share due to the availability of a sizable population base for the development and clinical testing of protein engineering applications. Further, the German market of protein engineering held the largest market share, and the UK market of protein engineering was the second-largest growing market in the European region.

The Asia-Pacific protein engineering market is expected to grow at the fastest CAGR from 2023 to 2032. This is due to the high prevalence of autoimmune, cardiovascular, and cancer diseases in developing Asian nations. Due to the significant economic development in emerging countries like India and China, unexplored potential in this region is also anticipated to help the sector thrive. Moreover, China’s market of protein engineering held the largest market share, and the Indian market of protein engineering was the fastest-growing market in the Asia-Pacific region.

Protein Engineering Key Market Players & Competitive Insights

Leading market players are investing heavily in research and development to expand their product lines, which will help the market of protein engineering, grow even more. Market participants are also engaging in a variety of strategic measures in order to grow their businesses  presence, with significant market development such as new product releases, contractual agreements, mergers and acquisitions, increased investments, and so on partnerships with other organisations. The protein engineering industry must offer cost-effective items to expand and survive in a more competitive and developing market condition.

One of the most important company strategies is to manufacture locally to save operational costs. manufacturers use in the  protein engineering industry to benefit clients and increase the market sector. In recent years, the protein engineering industry has provided some of the greatest significant benefits to medicine. Major players in the protein engineering market, including Agilent Technologies (U.S.), AB-Sciex (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Bruker Corp. (U.S.), GE Healthcare (U.K.), Perkin Elmer (U.S.), Sigma-Aldrich Corp. (U.S.), Thermo Fisher Scientific (U.S.), and Waters Corp. (U.S).

Agilent Technologies, Inc. offers fundamental bio-analytical and electronic measurement solutions to the chemical analysis, communications, electronics, and life sciences industries. The business provides semiconductor and board testing and electronic and bioanalytical measurements. In October 2020, The Agilent Seahorse XFp Analyzer, a device for assessing metabolic activity in living cells that can be utilized in protein engineering research, was introduced by Agilent Technologies.

AbbVie Inc. researches and develops pharmaceutical products. The company produces pharmaceutical medications for specialized treatment fields like immunology, chronic renal disease, hepatitis C, women's health, oncology, and neuroscience. Multiple sclerosis, Parkinson's, and Alzheimer's disease are just a few of the illnesses that AbbVie treats. In March 2022, for treating moderately to highly active ulcerative colitis, the U.S. FDA gave AbbVie Inc. permission to use RINVOQ (upadacitinib), a new medication.

Key Companies in the market of Protein Engineering include

• Agilent Technologies (U.S.)


• AB-Sciex (U.S.)


• Bio-Rad Laboratories, Inc. (U.S.)


• Bruker Corp. (U.S.)


• GE Healthcare (U.K.)


• Perkin Elmer (U.S.)


• Sigma-Aldrich Corp. (U.S.)


• Thermo Fisher Scientific (U.S.)


• Waters Corp. (U.S)

Protein Engineering Industry Developments

January 2021:A research partnership between Amgen and Generate Biomedicines was announced to identify and develop protein therapies for five clinical targets across various therapeutic domains and delivery systems.

December 2021:A major provider of software for biopharmaceutical protein characterization and proteomics analysis, Protein Metrics, Inc., was acquired by Insightful Science, a software firm that enables the cloud for scientific discovery. By extending the Company's R&D value chain, the purchase opens up the biopharmaceutical protein analysis market and removes data analysis bottlenecks currently connected to extensive protein research.

February 2022:The Tierra Protein Platform, an e-commerce platform that enables customers to obtain distinctive protein engineering items made, verified, and delivered to them in only a few clicks, was introduced by Tierra Biosciences.

Protein Engineering Market Segmentation

Protein Engineering Type Outlook

• Instrument


• Reagent


• Services & Software

Protein Engineering Application Outlook

• Food & Detergent Industries


• Environment


• Medical


• Biopolymer Production


• Nano Biotechnology

Protein Engineering Method Outlook

• Rational Protein Design


• Directed Evolution

Protein Engineering End User Outlook

• Pharmaceutical & Biotechnology Companies


• Contract Engineering Organizations


• Academic Research Institutes

Protein Engineering Regional Outlook

• North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  


• Europe
  
  
  
  • Germany
  
  
  • France
  
  
  • UK
  
  
  • Italy
  
  
  • Spain
  
  
  • Rest of Europe
  
  
  
  


• Asia-Pacific
  
  
  
  • China
  
  
  • Japan
  
  
  • India
  
  
  • Australia
  
  
  • South Korea
  
  
  • Australia
  
  
  • Rest of Asia-Pacific
  
  
  
  


• Rest of the World
  
  
  
  • Middle East
  
  
  • Africa
  
  
  • Latin America