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Preparative and Process Chromatography Market Research Report Information By Type (Process Chromatography, Preparative Chromatography), By Product (Chemicals & Reagents, Resins, Columns, Systems), By Chromatography Type (Liquid Chromatography, Gas Chromatography, Others), By End User (Biotechnology and Pharmaceutical Industries, Food & Beverage Industries, Academic Research Laboratories, Others), And By Region (North America, Europe, Asia-Pacific, And Rest Of The World) –Market Forecast Till 2032


ID: MRFR/HC/9227-HCR | 120 Pages | Author: Kinjoll Dey| December 2024

Global Preparative and Process Chromatography Market Overview


Preparative and process chromatography Market Size was valued at USD 6.94 billion in 2023. The preparative and process chromatography market industry is projected to grow from USD 7.42 billion in 2024 to USD 11.85 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 6.03% during the forecast period (2024 - 2032). The pharmaceutical and biotechnology sectors' growing need for and acceptance of monoclonal antibodies are two key market drivers anticipated to propel market expansion over the course of the projected period. 

Preparative and Process Chromatography Market Overview


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


October 2023: Tecan has launched Resolvex Prep, a cutting-edge benchtop automation solution designed specifically for chromatography sample preparation. This novel device has the potential to greatly enhance the effectiveness, accuracy, and reliability of chromatography sample preparation, which is highly important in the fields of analytical chemistry, proteomics, and biomedical research. Preparing samples for chromatography is a crucial and technically complex process. 


Even minor deviations might have a significant impact on subsequent experiments. By automating this process, laboratories can save time and costs while simultaneously enhancing the dependability of their results. Resolvex Prep is a specialized tool that is specifically tailored for chromatography workflows, making it an excellent choice for preparing samples for LC-MS analysis. The system has the ability to handle a diverse variety of batch sizes, ranging from five to 100 samples. Therefore, it is highly suitable for laboratories with a moderate level of work capacity. Furthermore, it offers an economical alternative for improving both efficiency and the quality of samples.


Preparative and Process Chromatography Market Trends




  • Increase in diabetes prevalence would spur market growth




According to the International Diabetes Federation, there will be 700 million persons with diabetes worldwide by 2045, up from an estimated 463 million in 2019. As the amount of insulin required to treat type 2 diabetes effectively is expected to increase by more than 20% over the next 12 years, there is an increase in demand for it. Within the age range of 20 to 79, type 2 diabetes affects more than half of the populations of China, India, and the United States. By 2030, these figures are anticipated to increase to more than 500 million in these nations. The price of insulin determines how much it will ultimately cost to treat chronic diabetes. In order to increase insulin availability, particularly in lower- to lower-middle-income nations, a price decrease is required. In order to produce high-purity insulin safely and with the highest yield, the purification chromatography must be optimized. Therefore, the need for improving and efficient methods of extraction and purification chromatography is becoming more urgent as the number of people with diabetes increases along with the demand for insulin. It is resulting in expanding the market CAGR and increasing the need for preparative and process chromatography.


Furthermore, the molecules known as monoclonal antibodies (mAb) are created in a lab and are precisely made to connect with cancer cells. They can act as replacement antibodies to boost or restore the immune system's attack on cancer cells. Making it simpler to distinguish between malignant and healthy cells, which can subsequently be treated or destroyed. Cancer is the second biggest cause of mortality in the world, and it is thought that 9.6 million people died from it in 2018. Cancer is responsible for roughly 1 in 6 deaths worldwide. A crucial step in the separation & purification of mAb is size exclusion chromatography (SEC), which has increased the demand for preparative and process chromatography and fueled the market's expansion. Thus, driving the preparative and process chromatography market revenue.


Preparative and Process Chromatography Market Segment Insights


Preparative and Process Chromatography Type Insights


The  preparative and process chromatography market segmentation, based on type includes Process Chromatography and Preparative Chromatography. The preparative chromatography segment dominated the market. The pharmaceutical sector uses this sort of chromatography to supply them with pure molecules by removing their contaminants and keeping the clinical supply of active pharmaceutical ingredients (API). This is why this segment has a big market share.


Figure 1:  Preparative and Process Chromatography Market, by Type, 2022 & 2032 (USD billion)


Preparative and Process Chromatography Market by Type


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Preparative and Process Chromatography Product Insights


The  preparative and process chromatography market segmentation, based on product, includes Chemicals & Reagents, Resins, Columns and Systems. The chemicals & reagents category generated the most income. Chemicals and reagents are crucial components of preparative and process chromatography procedures because they provide the environment necessary for achieving the desired purification and outcomes.


Preparative and Process Chromatography Chromatography Type Insights


The  preparative and process chromatography market segmentation, based on chromatography type, includes Liquid Chromatography, Gas Chromatography and Others. The liquid chromatography category generated the most income because it is widely used in many sectors. Depending on the kind, some important preparative and process chromatographic methods include gas chromatography, liquid chromatography, and high performance liquid chromatography (HPLC). This approach is used in various forms to isolate bioactive compounds from various sources. LC is essential to the production process in ensuring the quality of the final product. As a result, this market segment has experienced tremendous expansion thanks to the fast-expanding pharmaceutical and specialty chemical industries' increased interest.


Preparative and Process Chromatography End User Insights


The  preparative and process chromatography market segmentation, based on end user, includes Biotechnology and Pharmaceutical Industries, Food & Beverage Industries, Academic Research Laboratories, and Others. The biotechnology and pharmaceutical industries category generated the most income due to the widespread use of preparative and process chromatography in evaluating medication safety. To meet the demand for effective vaccination against the novel coronavirus in a shorter amount of time, various vaccine approaches, such as vaccines based on viral vectors, vaccines based on nucleic acids, and vaccines based on virus-like particles, have been developed.


Preparative and Process Chromatography Regional Insights


By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North American preparative and process chromatography market area will dominate this market. The regional market has been driven by the presence of a sizable number of important players and growing R&D programmes for disease management. Due to an increase in R&D spending by both commercial and public entities, the U.S. is significantly contributing to the regional market growth.


Further, the major countries studied in the market report are The U.S., Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 2:  Preparative And Process Chromatography Market Share By Region 2022 (%)


PREPARATIVE AND PROCESS CHROMATOGRAPHY MARKET SHARE BY REGION


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe preparative and process chromatography market accounts for the second-largest market share. The primary factor propelling market expansion is the rising need for process and preparative chromatography procedures in the life sciences, biotechnology, and food and beverage sectors. The presence of emerging economies in the area is also fueling the rise of the food and beverage and pharmaceutical industries. Further, the German preparative and process chromatography market held the largest market share, and the UK preparative and process chromatography market was the fastest growing market in the European region


The Asia-Pacific Preparative and process chromatography Market is expected to grow at the fastest CAGR from 2024 to 2032. The region's burgeoning biotechnology and pharmaceutical industries are anticipated to accelerate regional market expansion. The geographic growth of major market participants in Asian nations is further stimulating the regional market. Moreover, China’s preparative and process chromatography market held the largest market share, and the Indian preparative and process chromatography market was the fastest growing market in the Asia-Pacific region.


Preparative and process chromatography Key Market Players & Competitive Insights


Leading market players are investing heavily in research and development in order to expand their product lines, which will help the preparative and process chromatography market, grow even more. Market participants are also undertaking a variety of strategic activities to expand their  footprint, with important market developments including new product launches, contractual agreements, mergers and acquisitions, higher investments, and collaboration with other organizations. To expand and survive in a more competitive and rising market climate, preparative and process chromatography industry must offer cost-effective items.


Manufacturing locally to minimize operational costs is one of the key business tactics used by manufacturers in the  preparative and process chromatography industry to benefit clients and increase the market sector. In recent years, the preparative and process chromatography industry has offered some of the most significant advantages. Major players in the preparative and process chromatography market attempting to increase market demand by investing in research and development operations include Merck KGaA (Germany), Danaher Corporation (US), Bio-Rad Laboratories (US), Shimadzu Corporation (Japan), Thermo Fisher Scientific (US), Daicel Corporation (Japan), Waters Corporation (US), Novasep Holding S.A.S. (France), Agilent Technologies (US), PerkinElmer Inc. (US) and Others.


Danaher Corp. (Danaher) develops, produces, and sells industrial, commercial, and medical goods and services. It provides a vast array of testing equipment, communications solutions, automation solutions, water quality systems, life science research tools, professional microscopes, medical diagnostic solutions, product identification solutions, sustainable packaging design solutions, and sensors and controls solutions. In July 2021, Cytiva and Pall, both owned by Danaher, planned to invest a combined USD 1.5 billion to expand 13 locations in the Americas, Europe, and Asia. The investment project is concentrated on products used in the manufacturing of biologic drugs. The firms aim to spend about USD 600 million on chromatography resins, including on a new plant in the US, and about USD 400 million on the production of cell culture medium.


Waters Corporation offers goods and services for high-performance liquid chromatography. The business sells its goods to a variety of  businesses, including those that deal with chemicals, medicines, and environmental testing. Thermoanalysis, rheometry, calorimetry, and related software are all products that Waters designs, manufactures, distributes, and services. In March 2021, High-Performance Surface Technology was used in a liquid chromatograph that Waters Corporation unveiled. The Waters Acquity Premier Solution is a liquid chromatograph that uses the company's MaxPeak High-Performance Surface technology to enhance the quality of analytical results and do away with passivation.


Key Companies in the preparative and process chromatography market include



  • Merck KGaA (Germany)

  • Danaher Corporation (US)

  • Bio-Rad Laboratories (US)

  • Thermo Fisher Scientific (US)

  • Shimadzu Corporation (Japan)

  • Daicel Corporation (Japan)

  • Waters Corporation (US)

  • Agilent Technologies (US)

  • Novasep Holding S.A.S. (France)

  • PerkinElmer Inc. (US)

  • Others


Preparative and Process Chromatography Industry Developments


January 2022:Red Mesa Science & Refining, LLC and RotaChrom Technologies NA have formed a strategic relationship, according to the company that created the first Centrifugal Partition Chromatography (CPC) technology platform for industrial use. The two teams will work closely together to develop new and effective applications that make use of RotaChrom's centrifugal chromatography technology. They will also share and improve existing techniques.


April 2021:Launched by Tosoh Bioscience GmbH, a manufacturer of chromatographic solutions for biomolecule separation, the TSKgel FcR-IIIA-5PW HPLC column is the company's latest product. In the independent FcRaffinity chromatography portfolio for antibody drug analysis, this column is the second offering from Tosoh Corporation.


Preparative and Process Chromatography Market Segmentation


Preparative and Process Chromatography Type Outlook



  • Process Chromatography

  • Preparative Chromatography


Preparative and Process Chromatography Product Outlook



  • Chemicals & Reagents

  • Resins

  • Columns

  • Systems


Preparative and Process Chromatography Chromatography Type Outlook



  • Liquid Chromatography

  • Gas Chromatography

  • Others


Preparative and Process Chromatography End User Outlook



  • Biotechnology and Pharmaceutical Industries

  • Food & Beverage Industries

  • Academic Research Laboratories

  • Others


Preparative and Process Chromatography Regional Outlook



  • North America

    • US

    • Canada



  • Europe

    • Germany

    • France

    • UK

    • Italy

    • Spain

    • Rest of Europe



  • Asia-Pacific

    • China

    • Japan

    • India

    • Australia

    • South Korea

    • Australia

    • Rest of Asia-Pacific



  • Rest of the World

    • Middle East

    • Africa

    • Latin America



Report Attribute/Metric Details
Market Size 2023 USD 6.94 billion
Market Size 2024 USD 7.42 billion
Market Size 2032 USD 11.85 billion
Compound Annual Growth Rate (CAGR) 6.03% (2024-2032)
Base Year 2023
Market Forecast Period 2024-2032
Historical Data 2018- 2022
Market Forecast Units Value (USD Billion)
Report Coverage Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends
Segments Covered Type, Product, Chromatography Type, End User, and Region
Geographies Covered North America, Europe, Asia Pacific, and the Rest of the World
Countries Covered The U.S., Canada, German, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
Key Companies Profiled Merck KGaA (Germany), Bio-Rad Laboratories (US), Danaher Corporation (US), Thermo Fisher Scientific (US), Waters Corporation (US), Agilent Technologies (US), Shimadzu Corporation (Japan), Daicel Corporation (Japan), Novasep Holding S.A.S.(France), PerkinElmer Inc. (US) and Others
Key Market Opportunities Rising R&D initiatives for novel therapeutics
Key Market Dynamics Usage of chromatography in various applications Growing food safety concerns


Frequently Asked Questions (FAQ) :

The  preparative and process chromatography market size was valued at USD 6.94 Billion in 2023.

The  market is projected to grow at a CAGR of 6.03% during the forecast period, 2024-2032.

North America had the largest share in the  market

The key players in the market are Merck KGaA (Germany), Bio-Rad Laboratories (US), Thermo Fisher Scientific (US), Shimadzu Corporation (Japan), Daicel Corporation (Japan), Danaher Corporation (US), Waters Corporation (US), Agilent Technologies (US), Novasep Holding S.A.S.(France), PerkinElmer Inc. (US) and Others.

The preparative chromatography category dominated the market in 2022.

The liquid chromatography category had the largest share in the market.

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