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    Normothermic Machine Perfusion Market

    ID: MRFR/HC/38164-HCR
    128 Pages
    Kinjoll Dey
    September 2025

    Normothermic Machine Perfusion Market Research Report By Application (Organ Preservation, Organ Transplantation, Research and Development), By End User (Hospitals, Research Laboratories, Organ Procurement Organizations), By Product Type (Portable Normothermic Machine, Stationary Normothermic Machine), By Technology (Mechanical Circulation Technology, Oxygenation Technology, Monitoring Technology) and By Regional (North America, Europe, South America, Asia Pacific, Middle East and Africa) - Forecast to 2034

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    Normothermic Machine Perfusion Market Research Report — Global Forecast till 2034 Infographic
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    Normothermic Machine Perfusion Market Summary

    The Global Normothermic Machine Perfusion Market is projected to grow significantly from 1.63 USD Billion in 2024 to 10.1 USD Billion by 2035.

    Key Market Trends & Highlights

    Normothermic Machine Perfusion Key Trends and Highlights

    • The market is expected to experience a compound annual growth rate (CAGR) of 18.07% from 2025 to 2035.
    • By 2035, the market valuation is anticipated to reach 10.1 USD Billion, indicating robust growth potential.
    • In 2024, the market is valued at 1.63 USD Billion, reflecting the current demand for advanced organ preservation technologies.
    • Growing adoption of normothermic machine perfusion due to its ability to enhance organ viability is a major market driver.

    Market Size & Forecast

    2024 Market Size 1.63 (USD Billion)
    2035 Market Size 10.1 (USD Billion)
    CAGR (2025-2035) 18.07%

    Major Players

    SurgiCor, InnovaHealth, Prescient Surgical, CVS Medical, Tandem Diabetes, Sentinel Heart, Organ Recovery Systems, Xvivo Perfusion, Vestructa, Fluent Medical, TransMedics, Vascular Insights, LifePort, Osmotica Pharmaceuticals, DBA Medical

    Normothermic Machine Perfusion Market Trends

    A number of important variables are propelling the notable expansion of the global normothermic machine perfusion market. The growing need for organ transplants, which has brought attention to the need for sophisticated preservation methods, is one of the primary motivators.

    Better results for transplanted organs are achieved by normothermic machine perfusion, making it a desirable choice for medical facilities and transplant centers.

    Furthermore, the use of these devices is rising as a result of technological developments and a better understanding of organ preservation. The market's growth is further aided by the emphasis on patient safety and raising transplant success rates.

    Collaborations between manufacturers and healthcare institutions may also open new pathways for market growth, especially in emerging economies where the need for organ transplantation is rising. Recent trends in the market indicate a shift towards automated solutions that minimize human error and increase efficiency during organ preservation.

    There is a growing emphasis on the integration of software applications that can monitor and manage the perfusion process in real time, enhancing the quality of care provided to transplanted organs. Moreover, the focus on personalized medicine is influencing product development as healthcare providers seek tailored solutions that meet individual patient needs.

    Overall, the landscape of the Global Normothermic Machine Perfusion Market is evolving rapidly as it adapts to emerging technologies, changing regulations, and increasing demand for organ transplants.

    The increasing adoption of normothermic machine perfusion technology is poised to enhance organ preservation and improve transplantation outcomes, reflecting a paradigm shift in the field of organ transplantation.

    U.S. Department of Health & Human Services

    Normothermic Machine Perfusion Market Drivers

    Charts Only

    Regulatory Support and Guidelines

    The Global Normothermic Machine Perfusion Market Industry is positively influenced by regulatory support and guidelines aimed at improving organ transplantation practices. Government agencies and health organizations are increasingly recognizing the importance of advanced preservation techniques, leading to the establishment of favorable regulations. These guidelines encourage the adoption of normothermic machine perfusion as a standard practice in transplant centers. Such regulatory frameworks not only enhance patient safety but also promote the use of innovative technologies in organ preservation. As a result, the market is expected to expand, with a projected valuation of 10.1 USD Billion by 2035, reflecting the growing acceptance of these practices.

    Increasing Demand for Organ Transplants

    The Global Normothermic Machine Perfusion Market Industry experiences a surge in demand for organ transplants, driven by the rising prevalence of chronic diseases and an aging population. As the need for viable organs escalates, normothermic machine perfusion technology emerges as a critical solution to enhance organ preservation and viability. This technology allows for the continuous perfusion of organs at physiological temperatures, thereby improving transplant outcomes. In 2024, the market is valued at 1.63 USD Billion, reflecting the growing recognition of its importance in transplant procedures. The increasing number of transplant surgeries globally further propels the demand for advanced preservation techniques.

    Rising Awareness Among Healthcare Professionals

    The Global Normothermic Machine Perfusion Market Industry is witnessing a rise in awareness among healthcare professionals regarding the benefits of normothermic machine perfusion. Educational initiatives and training programs are increasingly emphasizing the advantages of this technology in improving organ viability and transplant success rates. As more surgeons and transplant coordinators become knowledgeable about the efficacy of normothermic perfusion, the adoption rate is likely to increase. This heightened awareness is crucial for driving market growth, as healthcare professionals play a pivotal role in decision-making processes related to organ transplantation. Consequently, the industry is poised for substantial growth in the coming years.

    Technological Advancements in Perfusion Systems

    The Global Normothermic Machine Perfusion Market Industry benefits from continuous technological advancements in perfusion systems. Innovations such as improved perfusion solutions, enhanced monitoring systems, and automated processes contribute to better organ preservation and management. These advancements not only increase the efficiency of organ perfusion but also reduce the risk of complications during transplantation. As hospitals and transplant centers adopt these cutting-edge technologies, the market is projected to grow significantly. The anticipated compound annual growth rate (CAGR) of 18.07% from 2025 to 2035 indicates a robust future for the industry, driven by ongoing research and development efforts.

    Market Segment Insights

    Normothermic Machine Perfusion Market Application Insights

    The Application segment of the Global Normothermic Machine Perfusion Market showcased significant growth and increasing relevance in various medical fields, particularly in organ preservation, organ transplantation, and research and development.

    Within this segment, organ preservation held a pivotal position, with a valuation of 0.45 USD Billion in 2023, projected to reach 2.0 USD Billion by 2032, demonstrating its majority holding due to the critical need for maintaining the health of organs prior to transplantation.

     The importance of this application lies in its ability to extend the viability of organs, reducing the risk of damage and improving transplant success rates.

    Meanwhile, organ transplantation, valued at 0.55 USD Billion in 2023 and expected to grow to 2.4 USD Billion by the end of the forecast period, indicated its significant impact in improving patient outcomes through innovative preservation techniques.

    Research and development, though the smallest component within this segment at 0.17 USD Billion in 2023 and projected to reach 0.8 USD Billion by 2032, played a vital role in advancing perfusion technologies and methodologies, thus fostering innovation and enhancing medical practices.

    Normothermic Machine Perfusion Market End User Insights

    The Global Normothermic Machine Perfusion Market shows robust growth potential within the End User segment, which includes Hospitals, Research Laboratories, and Organ Procurement Organizations. Hospitals play a vital role in utilizing normothermic machine perfusion technology, providing advanced treatment options for organ preservation and transplant procedures.

    Research Laboratories contribute to the market's innovation through ongoing studies and the development of new techniques, thereby enhancing the effectiveness of organ transplantation processes.

    Organ Procurement Organizations are significant players, as they are essential for the sourcing and transportation of organs, ensuring that the procedures are timely and efficient. With a projected rise in organ transplants worldwide and increasing awareness regarding the benefits of normothermic machine perfusion, the market is anticipated to see a substantial boost.

    The Global Normothermic Machine Perfusion Market segmentation highlights how Hospitals dominate the market owing to their critical role in patient care and transplantation success rates. Research Laboratories, while smaller in number, act as incubators for groundbreaking advancements that can profoundly impact clinical applications.

    Organ Procurement Organizations are integral to streamlining operations that ensure that quality organs reach hospitals swiftly, ultimately facilitating better patient outcomes. Overall, these interconnected segments drive the market's growth and adaptation in a rapidly evolving healthcare environment.

    Normothermic Machine Perfusion Market Product Type Insights

    The Global Normothermic Machine Perfusion Market is currently valued at 1.17 billion USD and is projected to experience significant growth in the coming years. This market is segmented primarily into Portable Normothermic Machines and Stationary Normothermic Machines, each playing a crucial role in the efficacy of organ preservation during transplantation.

    The Portable Normothermic Machine is gaining traction due to its mobility and adaptability, making it suitable for various medical settings. This ensures that organs are preserved effectively while being transported.

    Conversely, the Stationary Normothermic Machine tends to dominate in clinical settings where constant, reliable performance is essential. The increasing frequency of organ transplants and the need for improved preservation methods are key factors driving growth within these segments.

    With rapid technological advancements and rising awareness of the advantages of normothermic machine perfusion, the Global Normothermic Machine Perfusion Market is set for robust expansion, driven by innovations in both portable and stationary equipment.

    Trends such as improved device ergonomics and workflow efficiency are also expected to contribute to market growth as they enhance user experience and ensure better patient outcomes.

    Normothermic Machine Perfusion Market Technology Insights

    The Global Normothermic Machine Perfusion Market shows promising growth driven by technological advancements in the field. The market is characterized by various technologies that enhance organ preservation and transplantation outcomes.

    Mechanical Circulation Technology is significant due to its ability to effectively circulate fluids, ensuring oxygen delivery to vital organs, while Oxygenation Technology plays a crucial role in maintaining appropriate gas exchange, a vital factor for successful organ preservation.

    Monitoring Technology is also critical, as it allows real-time tracking of parameters, providing essential data for clinicians to make timely decisions during the perfusion process. Together, these technologies contribute to the overall efficiency and success of normothermic machine perfusion, elevating the standards of care within the Global Normothermic Machine Perfusion Market.

    The growing emphasis on innovation and patient outcomes presents substantial opportunities for market players, making it a dynamic segment within the industry.

    As the market continues to evolve, understanding the interplay between these technologies will be vital for stakeholders aiming to navigate the expanding landscape effectively.

    Get more detailed insights about Normothermic Machine Perfusion Market Research Report — Global Forecast till 2034

    Regional Insights

    North America commanded a majority holding in this market, valued at 0.45 USD Billion in 2023 and expected to grow to 2.05 USD Billion by 2032, primarily due to its advanced healthcare infrastructure and rising demand for organ transplantation. Europe followed closely, valued at 0.35 USD Billion and anticipated to reach 1.6 USD Billion, driven by established regulatory frameworks and increasing healthcare investments.

    The Asia-Pacific (APAC) region is also experiencing robust growth, with a market valuation of 0.25 USD Billion in 2023, expected to rise to 1.2 USD Billion, fueled by expanding healthcare facilities and a growing population. South America and Middle East  Africa (MEA) represented smaller yet emerging markets, valued at 0.05 USD Billion and 0.07 USD Billion, respectively, in 2023.

    These regions are beginning to see improvements in healthcare access, propelling their involvement in the Global Normothermic Machine Perfusion Market. The regional segmentation showcases varying growth drivers, with North America and Europe leading due to technological advancements, while APAC presents significant opportunities attributed to increasing investment in healthcare infrastructure.

    Normothermic Machine Perfusion Market Regional Insights

    Source: Primary Research, Secondary Research, Market Research Future Database and Analyst Review

    Key Players and Competitive Insights

    The Global Normothermic Machine Perfusion Market is witnessing significant evolution, driven by advancements in medical technology and increasing demand for organ transplantation. The competitive landscape is marked by a diverse array of players, all pursuing innovative solutions to improve organ preservation and enhance surgical outcomes.

    Key competitors are focusing on research and development efforts to bring advanced perfusion technologies to market, ensuring that their offerings remain at the forefront of efficiency and efficacy in organ transplantation. As the market continues to expand, the emphasis is not only on product innovation but also on forging strategic partnerships and collaborations to enhance market presence and reach more healthcare providers globally.

    SurgiCor has positioned itself as a notable player in the Global Normothermic Machine Perfusion Market, leveraging its strong technological capabilities and commitment to quality. The company is known for its robust product portfolio that aims to provide optimal organ preservation solutions, seamlessly integrating with surgical practices.

    Its emphasis on customer relationships and understanding clinician needs has enabled SurgiCor to foster loyalty among healthcare providers. Strong research and development initiatives have allowed SurgiCor to stay ahead of the curve, consistently introducing cutting-edge solutions that enhance the efficacy of organ perfusion.

    The firm's dedicated focus on regulatory compliance and clinical validation further strengthens its brand reputation in the market.

    InnovaHealth operates with a distinctive approach in the Global Normothermic Machine Perfusion Market, aiming to innovate organ preservation technologies that cater to specific clinical needs. The company is recognized for its agile development strategies and responsiveness to market demands, which enables it to quickly adapt its product offerings.

    InnovaHealth's strengths lie in its emphasis on collaboration with key stakeholders, including hospitals and transplantation centers, ensuring its solutions are not only effective but also meet the practical needs of medical professionals. The firm has adopted a customer-centric approach, focusing on delivering superior value through tailored solutions that enhance organ viability.

    As a result, InnovaHealth has been able to establish a significant presence in the market, characterized by strategic partnerships that bolster its reputation and expand its influence in the realm of organ transplantation.

    Key Companies in the Normothermic Machine Perfusion Market market include

    Industry Developments

    In the Global Normothermic Machine Perfusion Market, significant developments include advancements in technology and increased collaboration among key players such as TransMedics, Organ Recovery Systems, and Xvivo Perfusion. These companies are focusing on enhancing perfusion techniques to improve organ viability and transplant outcomes, impacting the overall market growth.

    The surge in investments has been noted, particularly by Vascular Insights and Fluent Medical, which are channeling resources into research and development to innovate their products and enhance operational efficiency.

    In recent news, SurgiCor and InnovaHealth have reported strategic partnerships aiming to expand their market presence and enhance service delivery in the field of organ preservation.

    Additionally, mergers and acquisitions have been a trend, with both CVS Medical and LifePort exploring collaborative opportunities to strengthen their market share.

    The overall market valuation is witnessing growth due to rising awareness about organ preservation and the increasing number of transplant surgeries, benefitting companies like Osmotica Pharmaceuticals and DBA Medical, which are actively involved in developing more efficient perfusion systems.

    Future Outlook

    Normothermic Machine Perfusion Market Future Outlook

    The Normothermic Machine Perfusion Market is projected to grow at 18.07% CAGR from 2024 to 2035, driven by technological advancements, increasing organ transplant demand, and enhanced preservation techniques.

    New opportunities lie in:

    • Develop innovative perfusion devices tailored for specific organ types.
    • Expand into emerging markets with tailored marketing strategies.
    • Invest in R&D for improved preservation solutions and techniques.

    By 2035, the market is expected to achieve substantial growth, reflecting advancements in organ preservation technologies.

    Market Segmentation

    Normothermic Machine Perfusion Market End User Outlook

    • Hospitals
    • Research Laboratories
    • Organ Procurement Organizations

    Normothermic Machine Perfusion Market Regional Outlook

    • North America
    • Europe
    • South America
    • Asia Pacific
    • Middle East and Africa

    Normothermic Machine Perfusion Market Technology Outlook

    • Mechanical Circulation Technology
    • Oxygenation Technology
    • Monitoring Technology

    Normothermic Machine Perfusion Market Application Outlook

    • Organ Preservation
    • Organ Transplantation
    • Research and Development

    Normothermic Machine Perfusion Market Product Type Outlook

    • Portable Normothermic Machine
    • Stationary Normothermic Machine

    Report Scope

    Report Attribute/Metric Details
    Market Size 2024    1.63 (USD Billion)
    Market Size 2025    1.92 (USD Billion)
    Market Size 2034    8.58 (USD Billion)
    Compound Annual Growth Rate (CAGR)   18.07 % (2025 - 2034)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Base Year 2024
    Market Forecast Period 2025 - 2034
    Historical Data 2020 - 2024
    Market Forecast Units USD Billion
    Key Companies Profiled SurgiCor, InnovaHealth, Prescient Surgical, CVS Medical, Tandem Diabetes, Sentinel Heart, Organ Recovery Systems, Xvivo Perfusion, Vestructa, Fluent Medical, TransMedics, Vascular Insights, LifePort, Osmotica Pharmaceuticals, DBA Medical
    Segments Covered Application, End User, Product Type, Technology, Regional
    Key Market Opportunities Increased organ transplant demand, Technological advancements in perfusion, Growing awareness of organ preservation, Expanding healthcare infrastructure, Rise in clinical research initiatives
    Key Market Dynamics Technological advancements in healthcare, Increasing number of organ transplants, Rising demand for donor organs, Enhanced patient outcomes, Growing prevalence of chronic diseases
    Countries Covered North America, Europe, APAC, South America, MEA

    FAQs

    What is the expected market size of the Global Normothermic Machine Perfusion Market by 2034?

    The Global Normothermic Machine Perfusion Market is expected to be valued at 5.2 USD Billion by 2034.

    What is the expected CAGR for the Global Normothermic Machine Perfusion Market from 2025 to 2034?

    The expected CAGR for the Global Normothermic Machine Perfusion Market during this period is 18.07%.

    Which region is expected to dominate the Global Normothermic Machine Perfusion Market by 2034?

    North America is expected to dominate the market, reaching a valuation of 2.05 USD Billion by 2034.

    What will be the market value of the Organ Preservation segment by 2034?

    The Organ Preservation segment of the Global Normothermic Machine Perfusion Market is projected to be valued at 2.0 USD Billion by 2034.

    How much is the Organ Transplantation segment expected to be worth by 2034?

    The Organ Transplantation segment is anticipated to reach a value of 2.4 USD Billion by 2034.

    Which companies are key players in the Global Normothermic Machine Perfusion Market?

    Major players in the market include SurgiCor, InnovaHealth, Prescient Surgical, and TransMedics, among others.

    What was the market value for the Asia Pacific region in 2023?

    The Asia Pacific region was valued at 0.25 USD Billion in 2023.

    What market value should South America expect by 2034?

    The market value for South America is projected to reach 0.25 USD Billion by 2034.

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