Mixed Mode Chromatography Resin Market Overview
As per MRFR analysis, the Mixed Mode Chromatography Resin Market Size was estimated at 2.55 (USD Billion) in 2022. The Mixed Mode Chromatography Resin Market Industry is expected to grow from 2.65(USD Billion) in 2023 to 3.78 (USD Billion) by 2032. The Mixed Mode Chromatography Resin Market CAGR (growth rate) is expected to be around 4.04% during the forecast period (2024 - 2032).
Key Mixed Mode Chromatography Resin Market Trends Highlighted
Key market drivers for mixed mode chromatography resins include the increasing demand for biopharmaceutical products, the need for efficient and cost-effective purification processes, and the development of new and innovative resins. Opportunities for growth in this market lie in the expansion of the biopharmaceutical industry, the adoption of mixed mode chromatography resins in various applications, and the development of customized resins for specific applications. Recent trends in the mixed mode chromatography resin market include the growing adoption of single-use resins, the development of resins with higher binding capacities and selectivities, and the use of mixed mode chromatography resins in combination with other purification techniques. These trends are expected to continue in the coming years, driving the growth of the mixed mode chromatography resin market.
Source Primary Research, Secondary Research, MRFR Database and Analyst Review
Mixed Mode Chromatography Resin Market Drivers
Rising Demand for Biologics Manufacturing
The increasing prevalence of chronic diseases, advancements in biotechnology, and the growing demand for personalized medicine are driving the growth of the biologics market. Biologics, such as monoclonal antibodies, recombinant proteins, and vaccines, are complex molecules that require specialized purification techniques. Mixed mode chromatography resins offer high selectivity and efficiency in the purification of biologics, making them a preferred choice in the biopharmaceutical industry.The growing demand for biologics is expected to continue to drive the growth of the mixed mode chromatography resin market in the coming years.
Technological Advancements in Chromatography Techniques
The Mixed Mode Chromatography Resin Market Industry is witnessing significant growth due to technological advancements in chromatography techniques. The development of new and innovative resins with improved binding capacities, selectivities, and regeneration capabilities is driving the growth of the market. Additionally, the integration of automation and high-throughput technologies in chromatography systems is enhancing the efficiency and productivity of purification processes, making mixed mode chromatography a more attractive option for manufacturers.
Increasing Adoption in Non-Biotechnological Applications
Mixed mode chromatography resins are gaining traction in non-biotechnological applications, such as food and beverage processing, environmental analysis, and pharmaceutical manufacturing. The ability of these resins to separate and purify complex mixtures of compounds is driving their adoption in various industries. For instance, in the food and beverage industry, mixed mode chromatography resins are used to purify and concentrate flavors, colors, and other additives.In the pharmaceutical industry, these resins are used to purify active pharmaceutical ingredients (APIs) and remove impurities.
Mixed Mode Chromatography Resin Market Segment Insights
Mixed Mode Chromatography Resin Market Resin Type Insights
They offer high binding capacity, excellent chemical stability, and are compatible with a wide range of solvents. Polymeric resins are primarily used in the purification of proteins, peptides, and other biomolecules. Ceramic Resins are gaining popularity due to their high mechanical strength, chemical inertness, and resistance to harsh conditions. They are commonly used in the separation of small molecules, such as organic acids and bases. The increasing demand for ceramic resins in the pharmaceutical and biotechnology industries is expected to drive market growth.Metallic Resins offer unique selectivity and binding properties. They are primarily used in the purification of metal ions and other inorganic compounds. The growing demand for metallic resins in the electronics and semiconductor industries is expected to contribute to market growth. Composite Resins combine the advantages of different resin types, offering tailored properties for specific applications. They are increasingly used in the purification of complex mixtures, such as those found in the food and beverage industry. The versatility and performance of composite resins are expected to drive market growth.The market segmentation by Resin Type provides valuable insights into the performance, applications, and growth potential of different types of Mixed Mode Chromatography Resins. This information enables manufacturers, suppliers, and end-users to make informed decisions about product development, marketing strategies, and investment opportunities.
Source Primary Research, Secondary Research, MRFR Database and Analyst Review
Mixed Mode Chromatography Resin Market Application Insights
The application segment of the Mixed Mode Chromatography Resin Market is diversified, with various applications driving market growth. Protein Purification holds a significant share of the market, expected to reach USD 1.25 billion by 2024. This growth is attributed to the increasing demand for protein-based therapeutics and advancements in purification technologies. Nucleic Acid Purification is another key application, with a projected market size of USD 0.98 billion by 2024. The rising demand for genetic testing and personalized medicine fuels this growth.Peptide Purification and Virus Purification also contribute to the market, with their respective market sizes estimated to reach USD 0.32 billion and USD 0.29 billion by 2024. Other Applications, including cell purification and antibody purification, are anticipated to exhibit steady growth, further expanding the market landscape.
Mixed Mode Chromatography Resin Market Sample Type Insights
The Sample Type segment of the Mixed Mode Chromatography Resin Market is segmented into Cell Culture, Fermentation Broth, Biological Fluids, Environmental Samples, and Food and Beverage Samples. Among these, the Cell Culture segment held the largest market share in 2023, accounting for around 35.0% of the Mixed Mode Chromatography Resin Market revenue. The growth of this segment can be attributed to the increasing demand for cell-based therapies and the rising adoption of mixed mode chromatography for the purification of monoclonal antibodies and other biologics.The Fermentation Broth segment is expected to witness significant growth over the forecast period, owing to the increasing production of biopharmaceuticals and the need for efficient purification techniques. Biological Fluids, Environmental Samples, and Food and Beverage Samples are other important segments of the Mixed Mode Chromatography Resin Market, with each segment exhibiting unique growth dynamics based on factors such as regulatory requirements, technological advancements, and industry trends.
Mixed Mode Chromatography Resin Market Separation Mode Insights
The Mixed Mode Chromatography Resin Market is segmented by Separation Mode into Size Exclusion Chromatography, Ion Exchange Chromatography, Affinity Chromatography, Hydrophobic Interaction Chromatography, and Reversed Phase Chromatography. Among these, Size Exclusion Chromatography held the largest share of the market in 2023, and it is expected to continue its dominance throughout the forecast period. The growth of this segment can be attributed to the increasing demand for Size Exclusion Chromatography in the purification of proteins and other biomolecules.Ion Exchange Chromatography is another major segment of the market, and it is expected to grow at a significant rate during the forecast period. The growth of this segment can be attributed to the increasing demand for Ion Exchange Chromatography in the purification of water and other industrial applications. Affinity Chromatography is a rapidly growing segment of the market, and it is expected to grow at a CAGR of over 5% during the forecast period. The growth of this segment can be attributed to the increasing demand for Affinity Chromatography in the purification of antibodies and other biomolecules.Hydrophobic Interaction Chromatography and Reversed Phase Chromatography are two other important segments of the market, and they are expected to grow at a moderate rate during the forecast period.
Mixed Mode Chromatography Resin Market Regional Insights
The regional segmentation of the Mixed Mode Chromatography Resin Market provides insights into the market's geographic distribution and growth potential. North America is expected to hold the largest market share in 2023, with a significant contribution from the United States. The region's strong pharmaceutical and biotechnology industries drive demand for mixed mode chromatography resins used in protein purification and biopharmaceutical manufacturing. Europe follows closely behind North America, with major markets in Germany, the United Kingdom, and France.The region's focus on healthcare and research and development contributes to the growing demand for mixed mode chromatography resins. APAC is projected to witness the fastest growth over the forecast period. China and India are key markets in the region, with increasing investments in the biopharmaceutical and healthcare sectors. South America and MEA are expected to have a modest share of the Mixed Mode Chromatography Resin Market. However, the growing healthcare and biotechnology industries in these regions are anticipated to drive future growth.
Source Primary Research, Secondary Research, MRFR Database and Analyst Review
Mixed Mode Chromatography Resin Market Key Players And Competitive Insights
Major players in Mixed Mode Chromatography Resin Market continually engage in development activities to expand their product portfolio and gain a competitive edge. They focus on introducing innovative products to cater to the evolving demands of the biopharmaceutical industry. Collaboration and partnerships are also common strategies adopted by leading players to strengthen their market position, combine expertise, and gain access to new technologies. Additionally, acquisitions allow companies to expand their capabilities and enter new geographical markets. Leading Mixed Mode Chromatography Resin Market players are investing in research and development to enhance the efficiency, productivity, and selectivity of their products. They aim to provide cost-effective solutions that meet the specific requirements of various biopharmaceutical applications. The Mixed Mode Chromatography Resin Market industry is characterized by intense competition, with numerous established and emerging players vying for market share.Tosoh Bioscience, a leading player in the Mixed Mode Chromatography Resin Market, has a long-standing reputation for providing high-quality and innovative products. The company's TOYOPEARL mixed-mode resins are widely recognized for their excellent performance in various bioseparation applications. Tosoh Bioscience continuously invests in research and development to enhance the capabilities of its products and meet the growing demands of the biopharmaceutical industry. The company has a presence and a strong distribution network, which allows it to cater to the diverse needs of customers worldwide.Bio-Rad Laboratories, another prominent player in the Mixed Mode Chromatography Resin Market, offers a comprehensive portfolio of resins designed for specific biomolecule purification requirements. The company's Nuvia brand of mixed-mode resins has gained wide acceptance in the industry due to its high binding capacity, selectivity, and ability to handle complex samples. Bio-Rad Laboratories emphasizes product quality and customer support and has established a vast network of distributors to ensure the availability and accessibility of its products. The company's commitment to innovation and customer satisfaction has contributed to its strong position in the Mixed Mode Chromatography Resin Market.
Key Companies in the Mixed Mode Chromatography Resin Market Include
- Phenomenex
- BioRad Laboratories
- GE Healthcare,
- Merck KGaA
- Porvair Sciences
- Novasep
- Tosoh Bioscience
- YMC Co. Ltd.
- Agilent Technologies
- BioWorks Technologies
- Sepharose
- Avantor Sciences
- Thermo Fisher Scientific
- Pall Corporation
Mixed Mode Chromatography Resin Market Industry Developments
The mixed mode chromatography resin market size was valued at USD 2.65 billion in 2023 and is projected to reach USD 3.78 billion by 2032, exhibiting a CAGR of 4.04% during the forecast period. The growth of the market is attributed to the increasing demand for biopharmaceuticals, rising prevalence of chronic diseases, and technological advancements in chromatography techniques.Recent news developments in the market include In February 2023, Merck KGaA announced the launch of a new mixed-mode chromatography resin, Purolite MMC-H, designed for the purification of monoclonal antibodies. In March 2023, Tosoh Corporation acquired the chromatography resin business of Repligen Corporation, expanding its portfolio of chromatography products.Current market trends include Growing adoption of single-use chromatography systems for biopharmaceutical manufacturing. Increasing demand for high-performance resins with enhanced selectivity and capacity. Development of new mixed-mode resins with tailored properties for specific applications.
Mixed Mode Chromatography Resin Market Segmentation Insights
Mixed Mode Chromatography Resin Market Resin Type Outlook
Polymeric Resins
Ceramic Resins
Metallic Resins
Composite Resins
Mixed Mode Chromatography Resin Market Application Outlook
Protein Purification
Nucleic Acid Purification
Peptide Purification
Virus Purification
Other Applications
Mixed Mode Chromatography Resin Market Sample Type Outlook
Cell Culture
Fermentation Broth
Biological Fluids
Environmental Samples
Food and Beverage Samples
Mixed Mode Chromatography Resin Market Separation Mode Outlook
Size Exclusion Chromatography
Ion Exchange Chromatography
Affinity Chromatography
Hydrophobic Interaction Chromatography
Reversed Phase Chromatography
Mixed Mode Chromatography Resin Market Regional Outlook
North America
Europe
South America
Asia Pacific
Middle East and Africa
| Report Attribute/Metric |
Details |
| Market Size 2022 |
2.55(USD Billion) |
| Market Size 2023 |
2.65(USD Billion) |
| Market Size 2032 |
3.78(USD Billion) |
| Compound Annual Growth Rate (CAGR) |
4.04% (2024 - 2032) |
| Report Coverage |
Revenue Forecast, Competitive Landscape, Growth Factors, and Trends |
| Base Year |
2023 |
| Market Forecast Period |
2024 - 2032 |
| Historical Data |
2019 - 2023 |
| Market Forecast Units |
USD Billion |
| Key Companies Profiled |
Phenomenex, BioRad Laboratories, GE Healthcare,, Merck KGaA, Porvair Sciences, Novasep, Tosoh Bioscience, YMC Co. Ltd., Agilent Technologies, BioWorks Technologies, Sepharose, Avantor Sciences, Thermo Fisher Scientific, Pall Corporation |
| Segments Covered |
Resin Type, Application, Sample Type, Separation Mode, Regional |
| Key Market Opportunities |
Growing demand for biopharmaceuticals Advancements in purification technologies Expanding application in protein purification Increasing focus on personalized medicine |
| Key Market Dynamics |
Rising demand for Biopharmaceuticals Advances in Bioprocess Technology Increasing adoption in Research Laboratories Growing Focus on Personalized Medicine Expansion of SingleUse Technologies |
| Countries Covered |
North America, Europe, APAC, South America, MEA |
Frequently Asked Questions (FAQ) :
The Mixed Mode Chromatography Resin Market is expected to be valued at 2.65 Billion USD in 2023.
The Mixed Mode Chromatography Resin Market is projected to grow at a CAGR of 4.04% from 2024 to 2032.
The Mixed Mode Chromatography Resin Market is expected to be valued at 3.78 Billion USD in 2032.
North America is expected to hold the largest market share in the Mixed Mode Chromatography Resin Market in 2023.
The Protein Purification segment is expected to hold the largest market share in the Mixed Mode Chromatography Resin Market in 2023.
Some of the key competitors in the Mixed Mode Chromatography Resin Market include Bio-Rad Laboratories, Inc., Merck KGaA, Thermo Fisher Scientific Inc., and Tosoh Corporation.
The major factors driving the growth of the Mixed Mode Chromatography Resin Market include the increasing demand for protein-based therapeutics, the growing adoption of biopharmaceutical manufacturing, and the rising prevalence of chronic diseases.
The major challenges faced by the Mixed Mode Chromatography Resin Market include the high cost of resin production, the stringent regulatory requirements, and the intense competition from alternative technologies.
The key trends that are expected to shape the future of the Mixed Mode Chromatography Resin Market include the development of new resin technologies, the increasing adoption of automation, and the growing focus on sustainability.
The potential opportunities for growth in the Mixed Mode Chromatography Resin Market include the expansion of the biopharmaceutical industry, the development of new applications, and the growing demand for personalized medicine.
