Microspheres Market Share

Global Microspheres Market Overview

Microspheres Market Size was valued at USD 2.1 Billion in 2023. The Microspheres market industry is projected to grow from USD 4.37 Billion in 2024 to USD 10.99 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 12.20% during the forecast period (2024 - 2032). Rising adoption pharmaceutical industry and biotechnology based companies are the prime market drivers helping the market to grow.

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

April 2024:

SpineThera, Inc., a privately held, clinical-stage pharmaceutical company focused on the development of SX600 (a novel formulation of extended-release dexamethasone microspheres for epidural injection for the management of lumbar radicular pain), and ProMed Pharma LLC, a leading contract manufacturer of polymer-based drug releasing dosage forms and combination device components, announced today that ProMed Pharma has acquired SpineThera's cGMP manufacturing operations. ProMed Pharma also received the option to license SpineThera's microsphere intellectual property, with the possibility of sublicensing to ProMed Pharma's clients.

ProMed Pharma has expanded its portfolio of polymer-based drug releasing dosage forms by acquiring SpineThera's controlled environment manufacturing suite and process equipment, which provide a robust manufacturing process supported by a cGMP quality management system and a highly experienced CMC team. SpineThera has been creating and producing biodegradable microspheres for ten years.

SpineThera's decision to sell its manufacturing business is consistent with the company's concentration on developing medicinal products.

SpineThera's CEO, Jeff Missling, said, "We are committed to improving patients' lives by developing innovative injectable drugs based on our proprietary micro-suspension platform technology." Our main asset, SX600, has shown best-in-class promise for treating lumbar radicular pain. Importantly, SpineThera retains sole ownership of the intellectual property that allows SX600. With this deal, our manufacturing staff will join ProMed Pharma, a very skilled CDMO with whom we have a long history of collaboration. SpineThera becomes a client of ProMed, who will manufacture the SX600 in the same cleanroom where we previously developed the technology and produced clinical batches. This acquisition increases working capital while lowering our fixed and recurrent expenditures." Missling said, "I applaud our workers who have made the transfer to ProMed for their years of committed service at SpineThera. We look forward to continuing to collaborate on the development of SX600 so that individuals suffering from severe lumbar radicular pain may have much better pain management."

Nouryon has introduced expancel HP92 microspheres, which can be used to reduce mass and resist high pressure in automotive underbody coatings and sealants, in June 2022. Currently, the manufacturing of these microspheres is taking place in Stockvik, Sweden and will also begin in Green Bay, Wisconsin by early 2023.

The release of Illumina’s new NovaSeq 6000 sequencing system was made public in December 2023. The newest model of the firm's sequencers is NovaSeq 6000 which possesses the best cost per base of all sequencers produced by Illumina and has the highest throughputs for large-scale RNA-seq or whole genome sequencing applications. Microfluidic chips collect DNA molecules for Illumina sequencing systems.

In December 2023, Merck finalized its acquisition of ArQit Quantum Inc., one of the pioneers in quantum cryptography offerings. The transaction is expected to close during H1-24. The use of ArQit's quantum-resistant encryption technology could help deal with cyber attacks targeting the healthcare sector, thereby safeguarding critical data. It is seeking whether microspheres are valid tools for quantum computing, and if so, it will completely change the pharmaceutical industry.

Microspheres Market Trends

• Growing adoption across medical technology is driving the market growth

The Market CAGR for microspheres is expanding at an accelerated rate because of the rise in adoption in medical technology. Microspheres are used by medical technology as an injectable biomaterial in urology, reconstructive surgery, and aesthetic surgery. Additionally, brachytherapy use it.

Medical technology typically uses microspheres made of polymer, glass, or ceramic for the production and testing of medical equipment. Microspheres, which have diameters more than 50 microns and come in a variety of colours, including red, blue, black, yellow, and green, are frequently utilised as challenge particles and tracers in medical equipment. The testing of filtration medium and systems, centrifugation and sedimentation processes, flow tracing and fluid dynamics, contamination control, and pharmaceutical manufacture are some common applications for coloured microspheres. Thus, driving the Microspheres market revenue.

Fluorescent-colored microspheres are used in medical applications such as microcirculation and biological research, imaging, and flow cytometry because they provide extra sensitivity for observation under microscopes, lasers, and other analytical methods. Microspheres are frequently utilized in medical diagnostics as injectable biomaterial, tissue filler, reagents for diagnostic equipment, and drug delivery vehicles thanks to recent advancements in quality and performance. Brazilian National Agency of Supplementary Health (ANS) approved SIR-Spheres Y-90 resin microspheres will be utilized to treat intermediate and advanced-stage hepatocellular carcinoma (HCC) in Brazil, according to a September 2022 announcement from Sirtex Medical.

In September 2022, ABK Biomedical Inc. declared that Easi-Vue embolic microspheres had been given FDA 510(k) clearance to treat patients with arteriovenous malformations or hypervascular tumours.

The United States' gross domestic product (GDP) accounted for 17.8% of healthcare spending in 2021 compared to 18.8% in 2020, according to the OECD. Along with the previously mentioned facts, ongoing innovation, technical advancement, and a variety of flexible applications may increase demand for microspheres in the medical technology sector.

Microspheres Market Segment Insights

Microspheres Material Insights

The  Microspheres market segmentation, based on material includes Synthetic Polymers and Natural Polymers. The synthetic polymers segment dominated the market. Although synthetic polymeric microspheres are widely used in clinical settings and have been shown to be safe and biocompatible, they also serve as bulking agents, fillers, embolic particles, drug delivery vehicles, and other functions. Their main drawback is that these microspheres have a tendency to migrate away from the injection site, which increases the risk of embolism and further organ damage.

Microspheres Type Insights

The  Microspheres market segmentation, based on type, includes Bioadhesive microspheres, Magnetic microspheres, Floating microspheres, Radioactive microspheres, and Polymeric microspheres. The bioadhesive microsphere category generated the most income. Bioadhesive microspheres are (small size and effective drug encapsulation) drug delivery methods that provide intimate and extended contact of active components with biological tissues and prolong interaction at target site. Increased residence periods enhance medication absorption benefits, which aid in better patient compliance, control over drug release characteristics, and a reduction in dose frequency.  

Microspheres Application Insights

The  Microspheres market segmentation, based on application, includes Drug carriers, Pulmonary Drug Deliveries, and Tissue Regeneration. The drug carriers category generated the most income. As a particulate medication delivery technology, microspheres are extremely essential due to their small size and other useful characteristics. In order to provide an effective dose form and imitate controlled drug release, microspheres have been shown to be a viable bridge. Microspheres are often free-flowing solid powders made of proteins or artificial polymers that are naturally biodegradable. Microspheres with particle sizes between 0.1 and 200 m can be administered orally, parenterally, nasally, ophthalmologically, transdermally, colonically, etc.

Figure 1  Microspheres Market, by End User, 2023 & 2032 (USD Billion)

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

Microspheres Regional Insights

By region, the study provides the market insights into North America, Europe, Asia-Pacific and Rest of the World. The North American Microspheres market area will dominate this market, owing to an increasing adoption in the healthcare industry.

Further, the major countries studied in the market report are The US, Canada, German, France, the UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

Figure 2  MICROSPHERES MARKET SHARE BY REGION 2022 (USD Billion)

Source Secondary Research, Primary Research, MRFR Database and Analyst Review

Europe Microspheres market accounts for the second-largest market share due to the rapid technological updates. Further, the German Microspheres market held the largest market share, and the UK Microspheres market was among the fastest-growing market in the European region

The Asia-Pacific Microspheres Market is expected to grow at the fastest CAGR from 2024 to 2032. The growth is attributed to the rising demand for technological innovation in medical industry. Moreover, China’s Microspheres market held the largest market share, and the Indian Microspheres market was among the fastest-growing market in the Asia-Pacific region.

Microspheres Key Market Players & Competitive Insights

Leading market players are expanding their product offerings, to acquire larger and higher competitive position in the market, which will lead the Microspheres market, even faster. Market participants are also adopting a variety of strategic activities to acquire leading position, with important market developments tactics including new product developments & upgrades, contractual agreements, mergers & acquisitions, collaborations, higher investments, and collaboration with other organizations. To grow and survive in a competitive and rising market climate, Microspheres industry must provide cost-effective items.

The manufacturers are laying emphasis on the use of local resources to achieve operational efficiency in the  Microspheres industry to benefit clients and increase the market sector. In recent years, the Microspheres industry has offered some of the most significant benefits to medicine. Major players in the Microspheres market, including Trelleborg AB, 3M, Luminex Corporation, Mo-Sci Corporation, Momentive Performance Materials Inc., Potter Industries LLC, Matsumoto Yushi Seiyaku Company, Chase Corporation, AzkoNobel N.V., Potters Industries LLC, and others, are attempting to increase market demand by investing in research and development operations.

Potters Industries, LLC, manufactures glass microspheres and is the industry's top producer, in a variety of sizes, chemistries, and surface coatings that enable use in various applications and end-uses. Glass microspheres made by the company offer the necessary retroreflectivity for traffic safety markings, clean, peen, and strengthen metals, provide light weighting, dimensional strengthening, and reduce thermal conductivity in plastics and polymers, reduce thermal expansion and improve flow in paints and coatings, reduce friction and weight in oil drilling, and enhance special conductivity applications in electronics. In August 2022, Two projects to increase the manufacturing of glass microspheres in North America have been announced by Potters Industries, LLC, a leader in highway safety worldwide. The first project, which was scheduled to be finished in September, will expand output of Direct Melt Glass Beads at our facility in Paris, Texas, by 20% to 25%. The second project will improve Muscatine, Iowa's capacity to produce standard highway glass beads by 25 to 30%. This project's construction is anticipated to be finished in time for the 2023 road marking season.

Innovative materials technology business Microsphere Technology specializes in covering microspheres. Their expertise is in the application of a variety of materials, including metals, metallic compounds, and colors, to the surface of hollow microspheres. These composite materials have a variety of uses in fields as diverse as water purification, defense, aerospace, marine and automotive coatings, diagnostics, and cosmetics due to their characteristics, such as their low density and buoyancy in aqueous environments. In February 2023, The assets of 3M's Advanced Materials company, formerly known as 3M Ceradyne and situated in Seattle, Washington, have been acquired by Mo-Sci, a top provider of high-tech glass development and manufacturing. Over 350 pieces of specialised equipment as well as its associated intellectual property were acquired. The deal's financial details weren't made public.

Key Companies in the Microspheres market include

• Trelleborg AB,


• 3M,


• Luminex Corporation,


• Mo-Sci Corporation,


• Momentive Performance Materials Inc.,


• Potter Industries LLC,


• Matsumoto Yushi Seiyaku Company,


• Chase Corporation,


• AzkoNobel N.V.,


• Potters Industries LLC

Microspheres Industry Developments

June 2022: In order to reduce weight and withstand high pressure in underbody coatings and sealants for the automotive sector, Nouryon created expancel HP92 microspheres. Presently, these microspheres are manufactured in Stockvik, Sweden, with the start of production in Green Bay, Wisconsin, in early 2023.

February 2022: Glass bubbles from 3M were used as insulation for NASA's new liquid hydrogen storage tank for the first time on a sizable industrial scale. High-strength, low-density hollow glass microspheres are what 3M glass bubbles are made of. The NASA Kennedy Space Centre began receiving 3M's glass bubbles in 2021 when the tank project moved into the insulation phase. For the project period, the company sent two tankers stocked with glass bubbles every day.

Microspheres Market Segmentation

Microspheres Material Outlook (USD Billion, 2018-2032)

• Synthetic Polymers


• Natural Polymers

Microspheres Type Outlook (USD Billion, 2018-2032)

• Bioadhesive microspheres


• Magnetic microspheres


• Floating microspheres


• Radioactive microspheres,


• Polymeric microspheres,

Microspheres Application Outlook (USD Billion, 2018-2032)

• Drug carriers


• Pulmonary Drug Deliveries


• Tissue Regeneration

Microspheres Regional Outlook

• North America
  
  
  
  • US
  
  
  • Canada
  
  
  
  


• Europe
  
  
  
  • Germany
  
  
  • France
  
  
  • UK
  
  
  • Italy
  
  
  • Spain
  
  
  • Rest of Europe
  
  
  
  


• Asia-Pacific
  
  
  
  • China
  
  
  • Japan
  
  
  • India
  
  
  • Australia
  
  
  • South Korea
  
  
  • Australia
  
  
  • Rest of Asia-Pacific
  
  
  
  


• Rest of the World
  
  
  
  • Middle East
  
  
  • Africa
  
  
  • Latin America