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Knee Cartilage Repair Market Research Report By Cartilage Defect Type (Osteoarthritis, Post-traumatic Cartilage Defects, Osteochondritis Dissecans, Degenerative Meniscal Tears), By Procedure Type (Microfracture, Osteochondral Autograft Transfer System (OATS), Autologous Chondrocyte Implantation (ACI), Cartilage Matrix-Associated Protein (COMP)-Based Tissue Engineering), By Graft Material (Autografts, Allografts, Synthetic Scaffolds, Biologics), By Application (Primary Knee Cartilage Repair, Revision Knee Cartilage Repair, Partial-Thickness


ID: MRFR/HC/24603-HCR | 128 Pages | Author: Rahul Gotadki| December 2024

Knee Cartilage Repair Market Overview


As per MRFR analysis, the Knee Cartilage Repair Market Size was estimated at 1.2(USD Billion) in 2023. The Knee Cartilage Repair Market Industry is expected to grow from 1.27(USD Billion) in 2024 to 2.16 (USD Billion) by 2032. The Knee Cartilage Repair Market CAGR (growth rate) is expected to be around 6.84% during the forecast period (2024 - 2032).


Key Knee Cartilage Repair Market Trends Highlighted


Key Market Drivers


The rising prevalence of knee osteoarthritis, sports injuries, and obesity are significant drivers of the knee cartilage repair market. Increasing awareness of surgical and non-surgical treatment options further fuels market growth. Technological advancements, such as minimally invasive techniques and regenerative therapies, have improved treatment outcomes and reduced recovery time, making cartilage repair procedures more accessible.


Opportunities to Explore


Emerging technologies and advancements in biomaterials hold immense potential for the growth of the knee cartilage repair market. The development of biocompatible scaffolds, hydrogels, and growth factors facilitates regeneration of damaged cartilage tissue. Furthermore, cell-based therapies and tissue engineering techniques offer promising avenues for the regeneration of functional cartilage in the future.


Trends in Recent Times


The shift towards minimally invasive and regenerative approaches is a notable trend in the knee cartilage repair market. Minimally invasive techniques, such as arthroscopic surgery, reduce surgical trauma and enable faster recovery. Regenerative therapies, including stem cell therapies and platelet-rich plasma injections, aim to promote cartilage regeneration and healing. Additionally, a growing emphasis on personalized medicine and tailoring treatment plans to individual patient needs is shaping the market landscape.


Knee Cartilage Repair Market


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Knee Cartilage Repair Market Drivers


Rising Prevalence of Osteoarthritis and Sports Injuries


Osteoarthritis is a degenerative joint disease that affects millions of people around the world. It is the most common type of arthritis, and it can cause pain, stiffness, and reduced mobility. Sports injuries are another major cause of knee cartilage damage. Athletes who participate in high-impact sports, such as football, basketball, and soccer, are at an increased risk of developing knee cartilage injuries. The rising prevalence of osteoarthritis and sports injuries is expected to drive the growth of the global knee cartilage repair market over the forecast period.


Technological Advancements in Cartilage Repair Procedures


Another important driving force of the market is technological advancement in the procedure of cartilage repair. It is worth mentioning that in recent years there have been significant achievements in the development of new and innovative techniques of cartilage repair. Experts believe that there are three main techniques for achieving such an objective that have been elaborated in the context under consideration. They are autologous cartilage transplantation, allogeneic cartilage transplantation and technological method called tissue engineering.

In the first case, a piece of cartilage from a healthy part of the patient’s body is taken and then transplanted to the damaged area. In the second case, the same transplantation is performed, but the cartilage is received from the donor. In the third case, the operation presupposes the growth of a piece of new cartilage in the laboratory and its subsequent transplantation to the patient. On the whole, it is possible to conclude that the above-mentioned technological advancements will significantly increase the level of effectiveness of the procedure and, thus, will lead to the further development of the global knee cartilage repair market.


Increasing Demand for Minimally Invasive Procedures


The increasing demand for minimally invasive procedures is another factor expected to drive the growth of the global knee cartilage repair market. Minimally invasive procedures are less invasive than traditional open surgery, and they offer a number of advantages, such as reduced pain, shorter recovery times, and fewer complications. Minimally invasive cartilage repair procedures include arthroscopic cartilage repair and microfracture. Arthroscopic cartilage repair involves using a small camera and surgical instruments to repair the damaged cartilage through small incisions.Microfracture involves drilling tiny holes in the damaged cartilage to stimulate the growth of new cartilage. The increasing demand for minimally invasive procedures is expected to drive the growth of the global knee cartilage repair market.


Knee Cartilage Repair Market Segment Insights


Knee Cartilage Repair Market Cartilage Defect Type Insights


The global market for knee cartilage repair can be segmented, based on cartilage defect type, into four types, namely, osteoarthritis, post-traumatic cartilage defects, osteochondritis dissecans, and degenerative meniscal tears. Osteoarthritis is the most common type of knee cartilage defect, with the market for the cartilage repair of this defect expected to constitute over 60% of the market share as of 2023. The increasing prevalence of osteoarthritis, largely stemming from higher rates of obesity, an aging population, and more active lifestyles, is a major driver of this growth.Post-traumatic cartilage defects are the second most common type, generally resulting from sports injuries and accidents.

Finally, while less common, osteochondritis dissecans and degenerative meniscal tears remain important contributors to this market. The market for knee cartilage repair for post-traumatic cartilage defects is expected to expand at a CAGR of 7.5% from 2023 to 2032, reaching a market valuation of USD 5.2 billion in 2032. As a result of these injuries, the increasing incidence of sports injuries is one of the most important drivers of this growth.Additionally, boiomsurgical techniques continue to develop, and more physicians and patients have become aware of cartilage repair procedures, both of which, in turn, contribute to this market.


Knee Cartilage Repair Market


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Knee Cartilage Repair Market Procedure Type Insights


According to the Procedure Type, the Global Knee Cartilage Repair Market has been divided into Microfracture, Osteochondral Autograft Transfer System, Autologous Chondrocyte Implantation and Cartilage Matrix-Associated Protein -Based Tissue Engineering. It has been revealed that Microfracture dominated the market in 2023, and is likely to maintain this leading position during the forecast period because of being a minimally invasive surgical procedure, cost-effectiveness, and relative rapidity of recovery.

In the meantime, Autologous Chondrocyte Implantation is to witness the highest CAGV rate in the period in question, mostly because it is used to relieve pain in joints for a long time and restore its function.To conclude, it should be stressed that the Global Market is to see a substantial expansion during the next few years because of the increase in the number of knee cartilage injuries, the rise of the aged population, and a better understanding of advanced treatment methods.


Knee Cartilage Repair Market Graft Material Insights


Autografts, allografts, synthetic scaffolds, and biologics are the four main types of graft materials used in knee cartilage repair procedures. Autografts, which are harvested from the patient's own body, are the most commonly used type of graft material. However, allografts, which are harvested from a donor, are becoming increasingly popular due to their lower risk of complications. Synthetic scaffolds, which are made from artificial materials, are another option for knee cartilage repair.

However, they are still in the early stages of development and have not yet been shown to be as effective as autografts or allografts.Biologics, which are derived from living organisms, are another promising option for knee cartilage repair. However, they are also still in the early stages of development and have not yet been shown to be as effective as autografts or allografts. In 2023, the global knee cartilage repair market was valued at USD 1.27 billion. The growth of the market is being driven by the increasing incidence of knee injuries, the rising popularity of minimally invasive surgical techniques, and the development of new and more effective graft materials.


Knee Cartilage Repair Market Application Insights


Application Segment Insights and Overview The global Knee Cartilage Repair Market is segmented by application into primary knee cartilage repair, revision knee cartilage repair, partial-thickness cartilage defects, and full-thickness cartilage defects. Among these, primary knee cartilage repair held the largest market share in 2023 and is projected to continue its dominance throughout the forecast period. The high prevalence of osteoarthritis and sports-related injuries has contributed to the growth of this segment. Revision knee cartilage repair is expected to witness significant growth in the coming years due to the increasing number of failed primary cartilage repair procedures.The partial-thickness cartilage defects segment is anticipated to grow at a steady pace during the forecast period, owing to the rising adoption of minimally invasive techniques such as microfracture and chondroplasty. Full-thickness cartilage defects, on the other hand, require more invasive procedures such as osteochondral autograft transplantation (OAT) and autologous chondrocyte implantation (ACI). This segment is expected to grow at a slower pace compared to other segments due to the higher cost and complexity of these procedures.


Knee Cartilage Repair Market Regional Insights


The Global Knee Cartilage Repair Market was valued at USD 1.27 billion in 2024 and is expected to reach USD 2.16 billion by 2032, exhibiting a CAGR of 6.84% during the forecast period. Regionally, North America held the largest market share in 2023 and is expected to maintain its dominance throughout the forecast period. The increased prevalence of knee injuries due to active lifestyles and rising obesity rates are key factors driving the market growth in this region.

Additionally, the presence of well-established healthcare infrastructure and favorable reimbursement policies further contribute to the market's growth in North America.The European market is expected to witness steady growth during the forecast period, owing to the increasing adoption of advanced cartilage repair techniques and the presence of a large patient population with knee cartilage defects. The APAC market is anticipated to exhibit significant growth, driven by the rising incidence of knee injuries among the rapidly growing population and the expanding healthcare industry in the region. South America and MEA are expected to experience moderate growth, primarily due to the increasing awareness of cartilage repair procedures and the growing demand for minimally invasive surgical techniques.


Knee Cartilage Repair Market Regional


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Knee Cartilage Repair Market Key Players And Competitive Insights


Major players in Knee Cartilage Repair Market are continuously investing in research and development to enhance their product offerings and expand their market presence. Leading Knee Cartilage Repair Market players are focused on developing innovative technologies and solutions to meet the evolving needs of patients and healthcare providers. The competitive landscape is characterized by strategic collaborations, partnerships, and acquisitions as companies seek to strengthen their position in the market.

Knee Cartilage Repair Market development is driven by technological advancements, increasing prevalence of knee cartilage injuries, and the rising demand for minimally invasive procedures.Among the leading Knee Cartilage Repair Market players, Arthrex is a prominent company known for its comprehensive portfolio of products and services for knee cartilage repair. The company offers a range of surgical implants, biologics, and instruments designed to address various cartilage defects. Arthrex has a strong global presence and is committed to providing innovative solutions to improve patient outcomes. Another leading player in the Knee Cartilage Repair Market is Smith & Nephew.

The company offers a wide range of products for cartilage repair, including cartilage plugs, scaffolds, and biologics. Smith & Nephew is focused on developing advanced therapies and technologies to enhance the healing process and restore knee function.Zimmer Biomet is a major player in the Knee Cartilage Repair Market, offering a comprehensive suite of products and services for cartilage repair. The company's portfolio includes cartilage implants, biological therapies, and surgical instruments. Zimmer Biomet is committed to providing high-quality solutions that meet the specific needs of patients and surgeons. In addition to these leading companies, other notable players in the Knee Cartilage Repair Market include Bioventus, MTF Biologics, and CartiHeal. These companies are actively involved in research and development to introduce new and improved solutions for cartilage repair, contributing to the overall growth and innovation in the market.


Key Companies in the Knee Cartilage Repair Market Include:



  • Zimmer Biomet

  • Braun Melsungen AG

  • Histogenics Corporation

  • Johnson Johnson

  • Orthofix Medical Holdings

  • TissueGene, Inc.

  • Medtronic

  • Cartilage Repair Technologies

  • Stryker Corporation

  • ChondroMimetics

  • Vericel Corporation

  • Arthrex

  • Collagen Solutions

  • Smith Nephew


Knee Cartilage Repair Market Industry Developments


The Global Knee Cartilage Repair Market is anticipated to reach a valuation of USD 2.16 Billion by 2032, expanding at a CAGR of 6.84% from 2024 to 2032. Advancements in surgical techniques, such as the introduction of minimally invasive procedures, are driving market growth. Moreover, the rising prevalence of knee injuries and osteoarthritis, coupled with increasing participation in sports activities, is fueling demand for knee cartilage repair procedures. Key players are focusing on developing innovative products and expanding their geographical presence to capitalize on growth opportunities. Recent developments include Arthrex's launch of the new Cellphix Cartilage Repair Device and the acquisition of CartiHeal by Bioventus.


Knee Cartilage Repair Market Segmentation Insights


Knee Cartilage Repair Market Cartilage Defect Type Outlook



    • Osteoarthritis

    • Post-traumatic Cartilage Defects

    • Osteochondritis Dissecans

    • Degenerative Meniscal Tears




Knee Cartilage Repair Market Procedure Type Outlook





    • Microfracture

    • Osteochondral Autograft Transfer System (OATS)

    • Autologous Chondrocyte Implantation (ACI)

    • Cartilage Matrix-Associated Protein (COMP)-Based Tissue Engineering




Knee Cartilage Repair Market Graft Material Outlook





    • Autografts

    • Allografts

    • Synthetic Scaffolds

    • Biologics




Knee Cartilage Repair Market Application Outlook





    • Primary Knee Cartilage Repair

    • Revision Knee Cartilage Repair

    • Partial-Thickness Cartilage Defects

    • Full-Thickness Cartilage Defects




Knee Cartilage Repair Market Regional Outlook





    • North America

    • Europe

    • South America

    • Asia Pacific

    • Middle East and Africa



Report Attribute/Metric Details
Market Size 2023 1.2(USD Billion)
Market Size 2024 1.27(USD Billion)
Market Size 2032 2.16(USD Billion)
Compound Annual Growth Rate (CAGR) 6.84% (2024 - 2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024 - 2032
Historical Data 2019 - 2023
Market Forecast Units USD Billion
Key Companies Profiled Zimmer Biomet, B. Braun Melsungen AG, Histogenics Corporation, Johnson Johnson, Orthofix Medical Holdings, TissueGene, Inc., Medtronic, Cartilage Repair Technologies, Stryker Corporation, ChondroMimetics, Vericel Corporation, Arthrex, Collagen Solutions, Smith Nephew
Segments Covered Cartilage Defect Type, Procedure Type, Graft Material, Application, Regional
Key Market Opportunities Arthroscopic Cartilage Repair Scaffold-Based Repair Cell-Based Therapy Biological Factors Technological Advancements
Key Market Dynamics Aging population, rising sports injuries, advancements in technology.
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The global knee cartilage repair market was valued at 1.27 billion U.S. dollars in 2024 and is projected to reach 2.16 billion U.S. dollars by 2032, exhibiting a CAGR of 6.84 % during the forecast period.

North America held the largest share of the market in 2023, accounting for around 40% of the global revenue. Asia-Pacific is expected to register the highest CAGR over the forecast period due to the rising prevalence of knee injuries, increasing geriatric population, and growing awareness about cartilage repair procedures in the region.

The increasing prevalence of knee injuries, particularly among athletes and the elderly, is a major factor driving the growth of the global knee cartilage repair market. Technological advancements, such as the development of minimally invasive techniques and the use of biologics, are also contributing to the market growth. Furthermore, rising healthcare expenditure and increasing awareness about cartilage repair procedures are expected to propel market growth in the coming years.

The major applications of knee cartilage repair include the treatment of Osteoarthritis, Traumatic Cartilage Defects, Osteochondritis Dissecans, and other cartilage defects. Among these, Osteoarthritis accounted for the largest share of the market in 2023 and is expected to maintain its dominance throughout the forecast period.

Some of the key competitors in the global knee cartilage repair market include Arthrex, Inc., Stryker Corporation, Smith Nephew plc, Zimmer Biomet Holdings, Inc., and Medtronic plc. These companies offer a range of products and services for knee cartilage repair, including surgical devices, implants, and biologics.

The current trends in the global knee cartilage repair market include the development of new and innovative surgical techniques, the use of advanced biomaterials, and the integration of robotics and AI in cartilage repair procedures. These trends are expected to drive the market growth in the coming years.

The global knee cartilage repair market faces challenges such as the high cost of procedures, limited reimbursement coverage, and the need for long-term patient follow-up. Additionally, the market is fragmented, with numerous competitors offering a range of products and services.

The future of the global knee cartilage repair market looks promising, with increasing demand for cartilage repair procedures due to the rising prevalence of knee injuries and osteoarthritis. Technological advancements and the development of new and innovative treatment options are expected to drive market growth in the coming years.

The key factors that will shape the future of the global knee cartilage repair market include technological advancements, the development of new and innovative treatment options, increasing demand for minimally invasive procedures, and rising healthcare expenditure. Additionally, the growing geriatric population and the increasing prevalence of knee injuries are expected to contribute to market growth in the coming years.

Some of the recent developments in the global knee cartilage repair market include the development of new surgical techniques, such as robotic-assisted surgery, and the use of advanced biomaterials, such as scaffolds and hydrogels. Additionally, there has been a growing focus on the development of personalized treatment options based on the patient's individual needs.

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