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Japan Closed System Drug Transfer Device Market

ID: MRFR/Pharma/47915-HCR
200 Pages
Garvit Vyas
February 2026

Japan Closed System Drug Transfer Device Market Research Report: Size, Share, Trend Analysis By Types (Membrane-to-membrane, Needleless System), By Component (Vial Access Devices, Syringe Safety Devices, Accessories, Bag/Line Access Devices), By Closing Mechanism (Push to Turn System, Color-to-color Alignment System, Leur Lock Systems, Click to Lock Systems), By Technology (Compartmentalize Devices, Diaphragm-Based Devices, Air Filtration Devices), and By End-users (Hospitals & Clinics, Specialty Centers, Others) - Growth Outlook & Industry Forecast 2025 To 2035

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Japan Closed System Drug Transfer Device Market Summary

As per Market Research Future analysis, the Japan closed system drug transfer device market Size was estimated at 60.0 USD Million in 2024. The Japan closed system drug transfer device market is projected to grow from 66.73 USD Million in 2025 to 193.0 USD Million by 2035, exhibiting a compound annual growth rate (CAGR) of 11.2% during the forecast period 2025 - 2035

Key Market Trends & Highlights

The Japan closed system drug transfer device market is experiencing robust growth driven by regulatory enhancements and technological advancements.

  • Regulatory enhancements are shaping the market landscape, ensuring compliance and safety in drug transfer processes.
  • Technological advancements are facilitating the development of more efficient and user-friendly closed system-drug-transfer-devices.
  • The largest segment in this market is the oncology segment, while the fastest-growing segment is anticipated to be the anesthesiology segment.
  • Rising demand for safety protocols and government initiatives for healthcare improvement are key drivers propelling market growth.

Market Size & Forecast

2024 Market Size 60.0 (USD Million)
2035 Market Size 193.0 (USD Million)
CAGR (2025 - 2035) 11.21%

Major Players

Baxter International Inc (US), B. Braun Melsungen AG (DE), Cardinal Health Inc (US), Cypress Medical Products LLC (US), ICU Medical Inc (US), Merit Medical Systems Inc (US), Pall Corporation (US), Terumo Corporation (JP)

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Japan Closed System Drug Transfer Device Market Trends

The closed system-drug-transfer-device market is experiencing notable developments, particularly in Japan, where regulatory frameworks are evolving to enhance safety and efficiency in drug handling. The increasing emphasis on minimizing exposure to hazardous drugs is driving demand for advanced transfer devices. Furthermore, the healthcare sector is witnessing a shift towards more automated and integrated systems, which may streamline operations and reduce the risk of contamination. This trend appears to be supported by ongoing investments in healthcare infrastructure and technology, suggesting a robust future for the market. In addition, the growing awareness of occupational safety among healthcare professionals is likely influencing the adoption of closed system-drug-transfer-devices. As hospitals and clinics prioritize the protection of their staff, the market may see a rise in the implementation of these devices. Moreover, the collaboration between manufacturers and healthcare providers could foster innovation, leading to the development of more efficient and user-friendly solutions. Overall, the closed system-drug-transfer-device market in Japan seems poised for growth, driven by regulatory support and a commitment to safety in drug administration.

Regulatory Enhancements

The regulatory landscape surrounding the closed system-drug-transfer-device market is evolving, with authorities in Japan implementing stricter guidelines to ensure safety in drug handling. These enhancements are likely to encourage healthcare facilities to adopt advanced devices that comply with new standards.

Technological Advancements

Innovations in technology are shaping the closed system-drug-transfer-device market, as manufacturers focus on developing more efficient and user-friendly devices. This trend may lead to increased adoption rates among healthcare providers seeking to improve operational efficiency.

Focus on Occupational Safety

There is a growing emphasis on occupational safety within healthcare settings, prompting facilities to prioritize the use of closed system-drug-transfer-devices. This trend indicates a shift towards protecting healthcare professionals from hazardous drug exposure.

Japan Closed System Drug Transfer Device Market Drivers

Rising Demand for Safety Protocols

The increasing emphasis on safety protocols within healthcare settings is driving the closed system-drug-transfer-device market. In Japan, healthcare facilities are prioritizing the protection of healthcare workers from hazardous drug exposure. This trend is reflected in the adoption of closed system-drug-transfer devices, which are designed to minimize the risk of contamination and exposure. As a result, the market is projected to grow at a CAGR of approximately 8% over the next five years. The heightened awareness of occupational safety is likely to propel investments in advanced drug transfer technologies, thereby enhancing the overall market landscape.

Focus on Infection Control Measures

The heightened focus on infection control measures within healthcare facilities is driving the closed system-drug-transfer-device market. In Japan, hospitals are increasingly adopting stringent protocols to prevent healthcare-associated infections, which has led to a surge in the use of closed system-drug-transfer devices. These devices are designed to reduce the risk of contamination during drug preparation and administration. The market is projected to grow at a rate of approximately 7% as healthcare providers recognize the importance of infection control in enhancing patient outcomes. This trend underscores the critical role of closed system-drug-transfer devices in maintaining high standards of safety in healthcare.

Technological Integration in Healthcare

The integration of advanced technologies in healthcare is a key driver for the closed system-drug-transfer-device market. In Japan, the rise of automation and digital solutions in medical practices is fostering the adoption of sophisticated drug transfer systems. These devices are increasingly equipped with features such as real-time monitoring and data analytics, which enhance their functionality and safety. The market is projected to expand by approximately 9% as healthcare facilities seek to leverage technology for improved efficiency and safety in drug handling. This trend indicates a shift towards more reliable and efficient healthcare delivery systems.

Aging Population and Increased Healthcare Needs

Japan's aging population is contributing to the growing demand for healthcare services, thereby impacting the closed system-drug-transfer-device market. As the elderly population increases, there is a corresponding rise in the need for safe and effective drug administration methods. The market is expected to grow by about 6% as healthcare providers seek to accommodate the complex medication regimens often required by older patients. This demographic shift necessitates the implementation of closed system-drug-transfer devices to ensure safety and efficacy in drug delivery, highlighting the importance of these devices in modern healthcare.

Government Initiatives for Healthcare Improvement

Government initiatives aimed at improving healthcare quality and safety are significantly influencing the closed system-drug-transfer-device market. In Japan, the Ministry of Health, Labour and Welfare has implemented various programs to promote the use of safer drug handling practices. These initiatives are expected to increase the adoption of closed system-drug-transfer devices across hospitals and clinics. The market is anticipated to witness a growth rate of around 7% as healthcare providers align with these government mandates. Such policies not only enhance patient safety but also encourage the integration of innovative technologies in drug administration.

Market Segment Insights

By Type: Membrane-To-Membrane Systems (Largest) vs. Needleless Systems (Fastest-Growing)

The Japan closed system drug transfer device market reveals a competitive landscape among key segment values. Membrane-To-Membrane Systems currently hold the largest market share, driven by their reliability and effectiveness in ensuring safe drug transfers. In contrast, Needleless Systems are emerging rapidly, appealing to healthcare providers seeking to improve convenience and reduce the risk of needlestick injuries. Growth trends in this segment indicate a significant shift towards safety-oriented solutions. The demand for Needleless Systems is increasing due to stringent regulations and a growing emphasis on patient safety. Additionally, advancements in technology and product innovation are propelling the adoption of these systems, making them a preferred choice for hospitals and clinics aiming to enhance operational efficiency and patient outcomes.

Membrane-To-Membrane Systems (Dominant) vs. Needleless Systems (Emerging)

Membrane-To-Membrane Systems are characterized by their established presence in the Japan closed system-drug-transfer-device market, primarily known for their efficiency in preventing contamination during drug transfers. This system's reliability has made it a dominant choice among healthcare professionals. On the other hand, Needleless Systems represent an emerging segment gaining traction due to their ability to minimize risk and improve safety protocols. These systems are increasingly being integrated into clinical practices, offering healthcare providers innovative solutions that meet the growing demand for safer and more efficient drug administration methods.

By Component: Syringe Safety Devices (Largest) vs. Vial Access Devices (Fastest-Growing)

In the Japan closed system-drug-transfer-device market, the distribution of market share among segment values reveals that Syringe Safety Devices hold the largest portion, driven by their essential role in ensuring safe medication delivery. Vial Access Devices, while currently smaller in share, are gaining momentum as they are increasingly integrated into various healthcare applications, showcasing an evolving landscape within the sector. Growth trends in this segment are significantly influenced by stringent regulations and an increasing focus on patient safety. The rise in surgical procedures and medical innovations further propels demand for these devices. Emerging technologies and advancements in design also contribute to the appeal of Vial Access Devices, making them a fast-growing aspect of the market, particularly in the context of safety and efficiency demands in drug transfer mechanisms.

Syringe Safety Devices: Dominant vs. Vial Access Devices: Emerging

Syringe Safety Devices dominate the market due to their critical role in reducing needlestick injuries and ensuring safe drug administration, thus appealing to healthcare facilities prioritizing staff and patient safety. Their established presence and widespread adoption make them integral to many health institutions. In contrast, Vial Access Devices are emerging as significant players, particularly as innovations enhance their usability and safety features. Improvements in design and functionality are making these devices more appealing to healthcare professionals. As hospital protocols evolve to favor closed systems, the demand for Vial Access Devices is expected to rise, positioning them as a pivotal segment in the market.

By Closing Mechanism: Push To Turn System (Largest) vs. Click-To Lock System (Fastest-Growing)

The distribution of market share for closing mechanisms in the Japan closed system-drug-transfer-device market reveals a competitive landscape. The Push To Turn System currently commands the largest share, favored for its reliability and ease of use. In contrast, the Click-To Lock System is gaining traction, driven by an increasing demand for safety and effectiveness in drug transfer processes. The Color-To-Color Alignment System and Luer Lock Systems also play significant roles, yet their market presence is overshadowed by these two dominant mechanisms. Growth trends for this segment are shaped by innovation and regulatory demands. The rapid adoption of advanced technologies in drug delivery is propelling the Click-To Lock System's growth, as healthcare providers seek solutions that enhance safety and efficiency. The increasing focus on minimizing contamination and maximizing user experience drives the shift toward more sophisticated mechanisms, ensuring that market dynamics remain favorable for these evolving solutions.

Push To Turn System (Dominant) vs. Click-To Lock System (Emerging)

The Push To Turn System remains the dominant player in the Japan closed system-drug-transfer-device market, known for its robust design that ensures secure closures, minimizing the risk of contamination during drug transfer. Its widespread acceptance is a testament to its reliability in healthcare settings. Conversely, the Click-To Lock System is emerging as a competitive alternative, favored for its user-friendly operation and innovative design which enhances safety. As healthcare professionals become more aware of the importance of secure drug transfer methods, the Click-To Lock System is expected to capture a more significant portion of the market, appealing to those prioritizing both functionality and safety.

By Technology: Compartmentalize Devices (Largest) vs. Diaphragm-Based Devices (Fastest-Growing)

In the Japan closed system-drug-transfer-device market, Compartmentalize Devices hold the largest share among the various technology segments. This category has established itself as a preferred choice due to its effectiveness in ensuring safe drug transfer practices, thereby dominating market dynamics. Diaphragm-Based Devices, while smaller in market share, are quickly gaining traction and appeal due to their innovations that enhance reliability and efficiency in drug handling. Recent growth trends indicate a robust shift towards more advanced technologies designed to improve safety and efficiency. The rising demand for safer drug transfer solutions, driven by increased regulatory scrutiny and a growing emphasis on minimizing contamination risks, is propelling Diaphragm-Based Devices forward as the fastest-growing segment. The technological advancements in this space are expected to keep the momentum strong, attracting significant investment and interest.

Technology: Compartmentalize Devices (Dominant) vs. Diaphragm-Based Devices (Emerging)

Compartmentalize Devices are recognized for their robust framework in securing and compartmentalizing drugs for safe transit, making them the dominant choice among healthcare providers. Their design not only ensures contamination prevention but also supports efficient drug transfer mechanisms. On the other hand, Diaphragm-Based Devices are emerging as key players in the market. They offer unique benefits like enhanced sterilization capabilities and ease of use, which are critical in environments with stringent safety protocols. This segment is rapidly evolving with innovative designs that are responding to healthcare demands, indicating a promising future. Their growth is bolstered by technological improvements and a rising awareness of infection control, making them increasingly attractive in the evolving landscape of drug transfer solutions.

By End User: Hospitals & Clinics (Largest) vs. Specialty Centers (Fastest-Growing)

In the Japan closed system-drug-transfer-device market, the distribution of market share among end users is notably skewed towards hospitals and clinics, which command the largest portion. This segment is characterized by their extensive requirement for drug transfer safety and efficiency, leading to a significant adoption of closed system drug transfer devices. Specialty centers, although smaller in share, are rapidly increasing their utilization due to their niche services and specialized patient needs, positioning them as an emerging player in this market. Growth trends indicate that hospitals and clinics will continue to be the primary market drivers, but specialty centers are expected to grow at a faster rate. The increasing number of outpatient procedures and the rising prevalence of chronic diseases are pushing specialty centers to enhance their operational capabilities with advanced drug transfer technologies. This dual growth in both segments reflects a dynamic market adapting to changing healthcare demands in Japan.

Hospitals & Clinics (Dominant) vs. Specialty Centers (Emerging)

The hospitals and clinics segment represents the dominant force in the Japan closed system-drug-transfer-device market. These institutions prioritize patient safety and regulatory compliance, leading to widespread adoption of innovative drug transfer solutions. With substantial budgets and a focus on advanced healthcare delivery, hospitals are often the first to integrate new technologies. On the other hand, specialty centers are emerging as vital contributors to this market, driven by specific medical practices requiring specialized care. Their agility in adopting cutting-edge technologies allows them to respond swiftly to market demands, making them an increasingly relevant player. This evolving landscape highlights the need for manufacturers to cater to varying requirements across these end user segments.

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Key Players and Competitive Insights

The closed system-drug-transfer-device market in Japan is characterized by a competitive landscape that is increasingly shaped by innovation, regulatory compliance, and the demand for safety in drug handling. Key players such as Baxter International Inc (US), B. Braun Melsungen AG (DE), and Terumo Corporation (JP) are actively pursuing strategies that emphasize technological advancements and partnerships to enhance their market positions. Baxter International Inc (US) focuses on developing advanced drug delivery systems, while B. Braun Melsungen AG (DE) emphasizes sustainability and eco-friendly practices in its product offerings. Terumo Corporation (JP) is leveraging its strong local presence to expand its product range and improve customer engagement, collectively shaping a dynamic competitive environment.
In terms of business tactics, companies are increasingly localizing manufacturing to reduce lead times and optimize supply chains. The market structure appears moderately fragmented, with several players vying for market share, yet the influence of major companies remains substantial. This competitive structure allows for a diverse range of products and innovations, fostering a healthy environment for growth and development.
In October 2025, Baxter International Inc (US) announced the launch of a new closed system drug transfer device designed to enhance safety and efficiency in drug preparation. This strategic move is likely to strengthen Baxter's position in the market by addressing the growing concerns regarding drug contamination and safety, thereby appealing to healthcare providers seeking reliable solutions.
In September 2025, B. Braun Melsungen AG (DE) unveiled a partnership with a leading technology firm to integrate AI capabilities into its drug transfer systems. This collaboration is expected to enhance the functionality of their devices, allowing for real-time monitoring and data analytics, which could significantly improve patient outcomes and operational efficiency.
In August 2025, Terumo Corporation (JP) expanded its manufacturing capabilities by investing in a new facility dedicated to producing closed system drug transfer devices. This investment not only signifies Terumo's commitment to meeting the increasing demand for safe drug handling but also positions the company to respond more effectively to market fluctuations and customer needs.
As of November 2025, the competitive trends in the closed system-drug-transfer-device market are increasingly defined by digitalization, sustainability, and the integration of advanced technologies such as AI. Strategic alliances are becoming more prevalent, allowing companies to pool resources and expertise to drive innovation. The shift from price-based competition to a focus on technological differentiation and supply chain reliability is evident, suggesting that future competitive advantages will hinge on the ability to innovate and adapt to evolving market demands.

Key Companies in the Japan Closed System Drug Transfer Device Market include

Industry Developments

Recent developments in the Japan Closed System Drug Transfer Device Market indicate significant advancements and focus on safety and efficiency in medical facilities. Companies like C.R. Bard, Baxter International, and West Pharmaceutical Services have been enhancing their product offerings to meet the growing demand for safety-engineered devices.

Notably, in June 2023, Vygon announced a strategic collaboration with a leading Japanese pharmaceutical company to drive innovation in drug transfer safety, showcasing the increasing importance of local partnerships.

Moreover, in July 2022, Thermo Fisher Scientific expanded its presence in Japan by opening a new facility focused on production innovations in drug delivery systems, reflecting the market's growth potential. In terms of mergers and acquisitions, there are reports of C.R. Bard considering strategic acquisitions to bolster its market share in Japan, although no specific transactions have been finalized as of October 2023.

The increasing focus on patient safety regulations and the rising incidence of oncology treatments are contributing to the overall market valuation growth, positioning Japan as a pivotal region for investments in closed-system drug transfer technologies. The market is expected to continue evolving with the need for improved healthcare solutions.

Future Outlook

Japan Closed System Drug Transfer Device Market Future Outlook

The Closed System Drug Transfer Device Market in Japan is projected to grow at 11.21% CAGR from 2025 to 2035, driven by increasing safety regulations and technological advancements.

New opportunities lie in:

  • Development of integrated software solutions for device management.
  • Expansion into home healthcare markets with portable devices.
  • Partnerships with hospitals for customized training programs.

By 2035, the market is expected to achieve substantial growth, reflecting evolving healthcare needs.

Market Segmentation

Japan Closed System Drug Transfer Device Market Type Outlook

  • Membrane-To-Membrane Systems
  • Needleless Systems

Japan Closed System Drug Transfer Device Market End User Outlook

  • Hospitals & clinics
  • Specialty centers
  • Others

Japan Closed System Drug Transfer Device Market Component Outlook

  • Vial Access Devices
  • Syringe Safety Devices
  • Bag/Line Access Devices
  • Accessories

Japan Closed System Drug Transfer Device Market Technology Outlook

  • Compartmentalize Devices
  • Diaphragm-Based Devices
  • Air Filtration Devices

Japan Closed System Drug Transfer Device Market Closing Mechanism Outlook

  • Push To Turn System
  • Color-To-Color Alignment System
  • Luer Lock Systems
  • Click-To Lock System

Report Scope

MARKET SIZE 2024 60.0(USD Million)
MARKET SIZE 2025 66.73(USD Million)
MARKET SIZE 2035 193.0(USD Million)
COMPOUND ANNUAL GROWTH RATE (CAGR) 11.21% (2025 - 2035)
REPORT COVERAGE Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
BASE YEAR 2024
Market Forecast Period 2025 - 2035
Historical Data 2019 - 2024
Market Forecast Units USD Million
Key Companies Profiled Baxter International Inc (US), B. Braun Melsungen AG (DE), Cardinal Health Inc (US), Cypress Medical Products LLC (US), ICU Medical Inc (US), Merit Medical Systems Inc (US), Pall Corporation (US), Terumo Corporation (JP)
Segments Covered Type, Component, Closing Mechanism, Technology, End User
Key Market Opportunities Growing demand for safety and efficiency in drug handling drives innovation in closed system-drug-transfer-device market.
Key Market Dynamics Rising regulatory scrutiny drives innovation and adoption of closed system-drug-transfer-devices in Japan's healthcare sector.
Countries Covered Japan
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FAQs

What is the projected market size of the Japan Closed System Drug Transfer Device Market in 2024?

The Japan Closed System Drug Transfer Device Market is expected to be valued at 36.0 million USD in 2024.

What is the expected market size for the Japan Closed System Drug Transfer Device Market by 2035?

By 2035, the Japan Closed System Drug Transfer Device Market is anticipated to reach a value of 120.0 million USD.

What is the expected compound annual growth rate (CAGR) for the market between 2025 and 2035?

The market is expected to exhibit a CAGR of 11.567 percent from 2025 to 2035.

Which segment of the Japan Closed System Drug Transfer Device Market is expected to grow the fastest?

The Needleless System segment is projected to see significant growth, reaching 70.0 million USD by 2035.

How much is the Membrane to Membrane segment valued at in 2024?

The Membrane to Membrane segment is valued at 15.0 million USD in 2024.

Who are the key players in the Japan Closed System Drug Transfer Device Market?

Major players include C.R. Bard, Smiths Medical, Baxter International, and West Pharmaceutical Services, among others.

What are the main applications driving the market growth?

The primary applications driving growth include safe handling of hazardous drugs in medical facilities.

What challenges is the Japan Closed System Drug Transfer Device Market currently facing?

Challenges include regulatory compliance and the need for education on the safe use of these devices.

How has the competitive landscape of the market changed?

The competitive landscape has seen increased innovation and product development among key players.

What opportunities exist for investors in the Japan Closed System Drug Transfer Device Market?

Opportunities for investors include advancements in technology and rising demand for safety in drug administration.

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