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Inhaled Nitric Oxide No Delivery System Market Research Report: By Inhaled Nitric Oxide Concentration (100 ppm, 200 ppm, 300 ppm, 400 ppm, 500 ppm), By Delivery System (Nasal Cannula, Tracheal Tube, Ventilator, Face Mask), By Patient Population (Newborns, Children, Adults, Older Adults), By Indication (Pulmonary Hypertension, Respiratory Distress Syndrome, Asthma, Chronic Obstructive Pulmonary Disease), By End User (Hospitals, Clinics, Ambulatory Surgery Centers) and By Regional (North America, Europe, South America, Asia Pacific, Middle Ea


ID: MRFR/CnM/23355-HCR | 100 Pages | Author: Pradeep Nandi| December 2024

Global Inhaled Nitric Oxide No Delivery System Market Overview


The Inhaled Nitric Oxide No Delivery System Market Size was estimated at 1.04 (USD Billion) in 2022.The Inhaled Nitric Oxide No Delivery System Industry is expected to grow from 1.11(USD Billion) in 2023 to 2.0 (USD Billion) by 2032. The Inhaled Nitric Oxide No Delivery System Market CAGR (growth rate) is expected to be around 6.8% during the forecast period (2024 - 2032).


Key Inhaled Nitric Oxide No Delivery System Market Trends Highlighted


The global market for Inhaled Nitric Oxide (iNO) Delivery Systems is experiencing significant growth due to the increasing prevalence of respiratory conditions, such as acute respiratory distress syndrome (ARDS) and pulmonary hypertension in both preterm and term neonates. The rising demand for less invasive and more effective treatment options for these conditions is driving the demand for iNO No Delivery Systems.


Key market drivers include the growing number of premature births, increasing awareness of the benefits of iNO therapy, and advancements in technology leading to the development of more efficient and user-friendly delivery systems. Opportunities for growth lie in the expansion of iNO therapy into new indications, such as the treatment of chronic obstructive pulmonary disease (COPD) and cystic fibrosis.


Recent trends indicate a shift towards compact, easy-to-use iNO No Delivery Systems that can be deployed in critical care settings as well as home environments. The integration of monitoring and control features into these systems enhances patient safety and convenience. Additionally, the development of iNO formulations with improved stability and extended shelf life is expected to further support market growth.


Inhaled Nitric Oxide No Delivery System Market Overview


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Inhaled Nitric Oxide No Delivery System Market Drivers


Increasing Prevalence of Respiratory Diseases


The rising incidence of respiratory diseases, such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary hypertension, is a major factor driving the growth of the Inhaled Nitric Oxide No Delivery System Market Industry. These conditions require immediate medical attention and can lead to severe complications if left untreated. Inhaled nitric oxide (iNO) therapy has emerged as an effective treatment option for these diseases, as it helps to improve oxygenation and reduce airway inflammation.


As the prevalence of respiratory diseases continues to increase, the demand for iNO therapy is expected to rise, thereby propelling market growth.


Technological Advancements and Product Innovations


The Inhaled Nitric Oxide No Delivery System Market Industry is witnessing significant technological advancements and product innovations. Leading manufacturers are investing heavily in research and development to introduce advanced delivery systems that offer improved efficacy and patient convenience. For instance, the development of portable and user-friendly iNO delivery devices has increased the accessibility and ease of administration, making it more convenient for patients to receive treatment at home or in ambulatory settings.


Ongoing research is also focused on developing new formulations of iNO with enhanced stability and efficacy, further contributing to market growth.


Rising Awareness and Government Initiatives


Increased awareness among healthcare professionals and the population regarding high clinical efficacy and safety of treatment of respiratory diseases by inhaling nitric oxide may be ascribed to a number of educational campaigns, conferences, and publications. Various governmental initiatives and reimbursement policies, as well as those supported by international authorities, are also accelerating market growth due to their support of iNO therapy.


As an example, in such countries, as the US and Europe, the favorable reimbursement policies founded by governmental institutions are making the treatment more affordable and accessible, which also results in a larger market.


Inhaled Nitric Oxide No Delivery System Market Segment Insights:


Inhaled Nitric Oxide No Delivery System Market Inhaled Nitric Oxide Concentration Insights


The Inhaled Nitric Oxide Concentration segment plays a critical component of the Inhaled Nitric Oxide No Delivery System Market. The effectiveness of each concentration for specific therapeutic applications directly affects the growth of the market, thus the discussions for the five key concentrations: 100 ppm, 200 ppm, 300 ppm, 400 ppm, and 500 ppm. The 100 ppm concentration has a significant share, as it is mostly used in the treatment of pulmonary hypertension in neonates. Thus, the market is also larger and will grow from USD $1.11 billion in 2023 to USD $2.0 billion in 2032.


As such, the segment, which will be valued at about USD $1.2 billion in 2023, will grow, and by 2032, the market will be at USD $2.2 billion, with a CAGR of 7.1%. The 300 ppm concentration caters to a small market and is only used in the treatment of severe pulmonary hypertension. As such, it will be valued at USD $0.9 billion in 2023, and by 2032, the market will be at USD $1.6 billion, with a CAGR of 7.5%. The 400 ppm concentration is also small in the market share and is used in Research and Development. It will be valued at USD $0.7 billion, but by 2032, the market will be at USD $1.2 billion, with a CAGR of 7.0%.


The 500 ppm concentration is the least with limited uses in severe chronic respiratory conditions, such as Chronic Obstructive Pulmonary Disease and cystic fibrosis. It will be valued at around USD $0.6 billion in 2023. By 2032, the market will also be at USD $1.0 billion, with a CAGR of 6.5%. The market share of all the concentrations will eventually lead to the growth of the Inhaled Nitric Oxide No Delivery System Market.


Inhaled Nitric Oxide No Delivery System Market Inhaled Nitric Oxide Concentration Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Inhaled Nitric Oxide No Delivery System Market Delivery System Insights


The Inhaled Nitric Oxide No Delivery System Market is segmented by delivery system into Nasal Cannula, Tracheal Tube, Ventilator, and Face Mask. Among these, the Nasal Cannula segment holds the largest market share due to its ease of use and patient comfort. The growth of the market is attributed to the rising incidence of respiratory diseases, increasing awareness about the benefits of inhaled nitric oxide therapy, and technological advancements in delivery systems.


Inhaled Nitric Oxide No Delivery System Market Patient Population Insights


The Inhaled Nitric Oxide No Delivery System Market is segmented by Patient Population into Newborns, Children, Adults, and Older Adults. Among these segments, Newborns held the largest market share of 42.5% in 2023. The high prevalence of respiratory distress syndrome (RDS) and other respiratory conditions in newborns drives the demand for inhaled nitric oxide therapy. The Inhaled Nitric Oxide No Delivery System Market for Newborns is expected to reach USD 445 million by 2032, growing at a CAGR of 6.5%. The Children segment is also a significant contributor to the Inhaled Nitric Oxide No Delivery System Market, with a market share of 30.0% in 2023.


The increasing incidence of asthma and other respiratory diseases in children is fueling the growth of this segment. The market for Children is projected to expand at a CAGR of 6.2%, reaching USD 310 million by 2032. The Adults segment is expected to witness steady growth over the forecast period, with a CAGR of 6.0%. The rising prevalence of chronic obstructive pulmonary disease (COPD) and other respiratory conditions in adults is driving the demand for inhaled nitric oxide therapy. The market for Adults is anticipated to reach USD 225 million by 2032.


The Older Adults segment is expected to grow at a CAGR of 5.8%, reaching USD 110 million by 2032. The increasing incidence of respiratory infections and other age-related respiratory conditions is contributing to the growth of this segment.


Inhaled Nitric Oxide No Delivery System Market Indication Insights


The Inhaled Nitric Oxide No Delivery System Market is segmented by indication into Pulmonary Hypertension, Respiratory Distress Syndrome, Asthma, and Chronic Obstructive Pulmonary Disease. Among these, Pulmonary Hypertension is expected to hold the largest market share in 2023 and is projected to maintain its dominance throughout the forecast period. The Inhaled Nitric Oxide No Delivery System Market for Pulmonary Hypertension is expected to reach USD 0.65 billion in 2023 and is projected to grow at a CAGR of 6.4% to reach USD 0.95 billion by 2032.


The growth of this segment can be attributed to the increasing prevalence of pulmonary hypertension and the rising demand for inhaled nitric oxide therapy as a treatment option.


Inhaled Nitric Oxide No Delivery System Market End User Insights


End User. The global Inhaled Nitric Oxide Delivery System Market is segmented by end user into hospitals, clinics, and ambulatory surgery centers. Hospitals are expected to account for the largest share of the market in 2023, followed by clinics and ambulatory surgery centers. The growth of the hospital segment can be attributed to the increasing number of patients suffering from respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD). Clinics are also expected to witness significant growth in the market owing to the rising demand for outpatient services.


Ambulatory surgery centers are expected to grow at a moderate pace as they offer a cost-effective and convenient option for patients undergoing minor surgeries. In 2023, the Inhaled Nitric Oxide No Delivery System Market for hospitals was valued at USD 0.63 billion and is projected to reach USD 0.98 billion by 2032, exhibiting a CAGR of 6.1% during the forecast period. The growth of the hospital segment can be attributed to the increasing number of patients suffering from respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD).


Hospitals are equipped with advanced infrastructure and a team of skilled healthcare professionals, which makes them the preferred destination for patients seeking treatment for respiratory diseases. In 2023, the Inhaled Nitric Oxide No Delivery System Market for clinics was valued at USD 0.32 billion and is projected to reach USD 0.56 billion by 2032, exhibiting a CAGR of 6.8% during the forecast period. The growth of the clinic segment can be attributed to the rising demand for outpatient services. Clinics offer a convenient and cost-effective option for patients seeking treatment for minor illnesses and injuries.


The increasing number of clinics in both developed and developing countries is also contributing to the growth of this segment. In 2023, the Inhaled Nitric Oxide No Delivery System Market for ambulatory surgery centers was valued at USD 0.16 billion and is projected to reach USD 0.28 billion by 2032, exhibiting a CAGR of 6.5% during the forecast period. The growth of the ambulatory surgery center segment can be attributed to the increasing number of patients opting for outpatient surgeries. Ambulatory surgery centers offer a cost-effective and convenient option for patients undergoing minor surgeries.


The growing popularity of minimally invasive surgeries is also contributing to the growth of this segment.


Inhaled Nitric Oxide No Delivery System Market Regional Insights


The Inhaled Nitric Oxide No Delivery System Market is segmented into North America, Europe, APAC, South America, and MEA. North America is the largest regional market for inhaled nitric oxide no-delivery systems, owing to the high prevalence of respiratory diseases in the region. The market in Europe is also significant, driven by the increasing adoption of inhaled nitric oxide therapy in hospitals and clinics. The APAC region is expected to witness the fastest growth in the coming years due to the rising awareness of inhaled nitric oxide therapy and the growing number of respiratory disease cases in the region.


South America and MEA are relatively smaller markets, but they are expected to grow steadily in the coming years.


Inhaled Nitric Oxide No Delivery System Market Regional Insights


Source: Primary Research, Secondary Research, MRFR Database and Analyst Review


Inhaled Nitric Oxide No Delivery System Market Key Players And Competitive Insights:


Major players in Inhaled Nitric Oxide No Delivery System Market industry are continuously looking for the development of new products. Leading Inhaled Nitric Oxide No Delivery System Market players are also adopting various marketing strategies like R&D, innovation and expansion of their production line to cater to the Inhaled Nitric Oxide No Delivery System Market development. The Inhaled Nitric Oxide No Delivery System Market Competitive Landscape reveals that the market is getting intense, with major players planning various strategies to gain a lion’s share of the market.


ResMed is a leading company in the Inhaled Nitric Oxide No Delivery System Market. The company is headquartered in San Diego, California, and has operations in over 100 countries. ResMed develops, manufactures, and markets medical devices for the treatment of sleep apnea, chronic obstructive pulmonary disease (COPD), and other respiratory conditions. The company's products include CPAP machines, oxygen concentrators, and ventilators. ResMed has a strong commitment to research and development, and its products are known for their high quality and innovation.


Another major player in the Inhaled Nitric Oxide No Delivery System Market is GE Healthcare. The company is headquartered in Chicago, Illinois, and has operations in over 100 countries. GE Healthcare develops, manufactures, and markets a wide range of medical devices, including imaging systems, patient monitoring equipment, and anesthesia machines. The company's products are used in hospitals, clinics, and other healthcare settings around the world. GE Healthcare has a strong commitment to innovation, and its products are known for their advanced technology and reliability.


Key Companies in the Inhaled Nitric Oxide No Delivery System Market Include:




  • Fisher Paykel Healthcare




  • CareFusion




  • MESI




  • Medtronic




  • INO Therapeutics




  • Praxair Healthcare




  • Pall Corporation




  • Linde Healthcare




  • Teleflex Incorporated




  • Smiths Medical




  • GE Healthcare




  • Hamilton Medical




  • Air Liquide Healthcare




  • ICU Medical




  • Dräger




Inhaled Nitric Oxide No Delivery System Market Industry Developments


The global inhaled nitric oxide (iNO) no-delivery system market is projected to reach USD 1.11 billion by 2023, exhibiting a CAGR of 6.8% from 2024 to 2032. The increasing prevalence of respiratory diseases, particularly among preterm infants, is driving market growth. Moreover, rising demand for non-invasive respiratory support and technological advancements in iNO delivery systems are contributing to market expansion. Recent developments include the launch of compact and portable iNO devices, making it easier to administer the therapy in various settings. Additionally, research on the use of iNO in treating other respiratory conditions, such as acute respiratory distress syndrome (ARDS), is expected to create new market opportunities.


Inhaled Nitric Oxide No Delivery System Market Segmentation Insights


Inhaled Nitric Oxide No Delivery System Market Inhaled Nitric Oxide Concentration Outlook




    • 100 ppm

    • 200 ppm

    • 300 ppm

    • 400 ppm

    • 500 ppm  



Inhaled Nitric Oxide No Delivery System Market Delivery System Outlook




    • Nasal Cannula

    • Tracheal Tube

    • Ventilator

    • Face Mask



 Inhaled Nitric Oxide No Delivery System Market Patient Population Outlook




    • Newborns

    • Children

    • Adults

    • Older Adults



 Inhaled Nitric Oxide No Delivery System Market Indication Outlook




    • Pulmonary Hypertension

    • Respiratory Distress Syndrome

    • Asthma

    • Chronic Obstructive Pulmonary Disease



 Inhaled Nitric Oxide No Delivery System Market End User Outlook




    • Hospitals

    • Clinics

    • Ambulatory Surgery Centers  



Inhaled Nitric Oxide No Delivery System Market Regional Outlook




    • North America

    • Europe

    • South America

    • Asia Pacific

    • Middle East and Africa




  •  

Report Attribute/Metric Details
Market Size 2022 1.04(USD Billion)
Market Size 2023 1.11(USD Billion)
Market Size 2032 2.0(USD Billion)
Compound Annual Growth Rate (CAGR) 6.8% (2024 - 2032)
Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
Base Year 2023
Market Forecast Period 2024 - 2032
Historical Data 2019 - 2023
Market Forecast Units USD Billion
Key Companies Profiled Fisher Paykel Healthcare, CareFusion, MESI, Medtronic, INO Therapeutics, Praxair Healthcare, Pall Corporation, Linde Healthcare, Teleflex Incorporated, Smiths Medical, GE Healthcare, Hamilton Medical, Air Liquide Healthcare, ICU Medical, Dräger
Segments Covered Inhaled Nitric Oxide Concentration, Delivery System, Patient Population, Indication, End User, Regional
Key Market Opportunities 1 Growing Prevalence of Pulmonary Hypertension2 Technological Advancements in Delivery Devices3 Rising Demand in Developing Countries4 Favorable Reimbursement Policies5 Expansion into New Therapeutic Applications
Key Market Dynamics Rising prevalence of respiratory conditions Technological advancements Increasing demand for noninvasive treatments Growing geriatric population Government initiatives
Countries Covered North America, Europe, APAC, South America, MEA


Frequently Asked Questions (FAQ) :

The global inhaled nitric oxide (NO) delivery system market is expected to reach USD 2.0 billion by 2032, growing at a CAGR of 6.8% from 2024 to 2032. The increasing prevalence of respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), is driving the market growth.

North America is expected to hold the largest market share in the global inhaled nitric oxide (NO) delivery system market during the forecast period. The presence of a large number of patients suffering from respiratory diseases, coupled with a well-established healthcare infrastructure and high adoption of advanced medical technologies, contributes to the region's dominance.

The neonatal respiratory failure segment is anticipated to grow at the highest CAGR during the forecast period. The increasing number of premature births and the rising incidence of respiratory distress syndrome (RDS) in newborns are driving the demand for inhaled nitric oxide delivery systems in neonatal care units.

Key competitors in the global inhaled nitric oxide (NO) delivery system market include Hamilton Medical, Vyaire Medical, GE Healthcare, Drägerwerk AG Co. KGaA, and Smiths Medical. These companies offer a range of inhaled nitric oxide delivery systems, including nasal cannulas, face masks, and ventilators, catering to the needs of different patient populations and clinical settings.

The increasing prevalence of respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), is a major factor driving the growth of the global inhaled nitric oxide (NO) delivery system market. Additionally, the rising number of premature births and the growing demand for inhaled nitric oxide therapy in neonatal care units are contributing to market expansion.

The high cost of inhaled nitric oxide therapy and the limited reimbursement coverage in some regions pose challenges to the growth of the global inhaled nitric oxide (NO) delivery system market. Additionally, the need for specialized healthcare professionals to administer inhaled nitric oxide therapy can limit its accessibility in certain settings.

The growing adoption of inhaled nitric oxide therapy in emerging markets, coupled with the development of new and improved inhaled nitric oxide delivery systems, presents opportunities for growth in the global inhaled nitric oxide (NO) delivery system market. Additionally, the increasing awareness of the benefits of inhaled nitric oxide therapy among healthcare professionals is expected to drive market expansion.

Key trends in the global inhaled nitric oxide (NO) delivery system market include the development of non-invasive and portable inhaled nitric oxide delivery systems, the growing use of inhaled nitric oxide therapy in combination with other respiratory therapies, and the increasing adoption of telemedicine for remote monitoring of patients receiving inhaled nitric oxide therapy.

The global inhaled nitric oxide (NO) delivery system market is expected to witness continued growth in the coming years. The development of more effective and user-friendly inhaled nitric oxide delivery systems, along with the increasing prevalence of respiratory diseases, is likely to drive market expansion.

The growing availability of inhaled nitric oxide delivery systems has significant implications for healthcare providers and patients. Inhaled nitric oxide therapy can improve clinical outcomes for patients with respiratory diseases, such as asthma and COPD, and can reduce the need for mechanical ventilation. For healthcare providers, inhaled nitric oxide delivery systems offer a valuable tool for managing respiratory distress in critically ill patients.

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