The rise in heart diseases, including conditions like coronary heart disease, stroke, peripheral arterial disease, and aortic disease, is a significant reason for the growth of the hERG screening market. These heart-related issues are a leading cause of death worldwide for both men and women. The American College of Cardiology reports that an American experiences a heart attack approximately every 40 seconds.
In a given year, about 356,461 Americans face emergency medical services-assessed out-of-hospital cardiac arrest, with treatment initiated in 52% of cases. The initial recorded cardiac rhythm is often ventricular fibrillation, ventricular tachycardia, or shockable by an automated external defibrillator in only 18.7% of cases. The chances of adult survival to hospital discharge are around 10.4%, and only 8.4% have a good functional status at discharge.
Various factors contribute to the prevalence of cardiovascular diseases, such as sedentary lifestyles and common risk factors including hypertension (ranging from 28% in the United Arab Emirates to 41% in Libya and Morocco), diabetes (ranging from 4% in the Islamic Republic of Iran to 19% in Sudan), and hypercholesterolemia (ranging from 14% in Lebanon to 52% in the Islamic Republic of Iran).
This increase in the prevalence of heart diseases emphasizes the need for advancements in drug discovery for cardiac disorders. Consequently, this trend contributes to the overall growth of the hERG screening market.
In addition to the rising prevalence of heart diseases, lifestyle changes and risk factors play crucial roles in the escalating numbers. Sedentary lifestyles and common risk factors like hypertension, diabetes, and hypercholesterolemia contribute significantly to the growing burden of cardiovascular diseases.
Sedentary lifestyles, characterized by a lack of physical activity, are becoming increasingly prevalent in today's society. This lack of exercise can lead to various health issues, including obesity and cardiovascular diseases. Additionally, common risk factors such as hypertension, diabetes, and hypercholesterolemia are widespread in different regions, further fueling the rise in heart-related conditions.
Hypertension, or high blood pressure, is a significant risk factor for heart diseases. The prevalence of hypertension varies across regions, with rates ranging from 28% in the United Arab Emirates to 41% in Libya and Morocco. Similarly, diabetes, another common risk factor, shows varying prevalence, ranging from 4% in the Islamic Republic of Iran to 19% in Sudan.
Hypercholesterolemia, characterized by high levels of cholesterol in the blood, is yet another contributor to heart diseases. The prevalence of this condition varies widely, ranging from 14% in Lebanon to a staggering 52% in the Islamic Republic of Iran.
In conclusion, lifestyle factors and common risk elements significantly contribute to the increasing prevalence of heart diseases globally. This, in turn, emphasizes the urgent need for advancements in drug discovery to address and mitigate the impact of cardiovascular disorders, ultimately fostering the continued growth of the hERG screening market.
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