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    Diabetic Nephropathy Market

    ID: MRFR/Pharma/4209-HCR
    110 Pages
    Rahul Gotadki
    September 2025

    Diabetic Nephropathy Market Research Report Information by Diagnosis (Blood test, Urine tests, Imaging test, Renal function testing, kidney biopsy), Treatment (Medication, {Angiotensin-Converting Enzyme (ACE) Inhibitors, Angiotensin II Receptors Blockers, Antioxidant Inflammation Modulator, Calcium Channel Blockers, Diuretics, Others}, Kidney Dialysis, Transplant), Indication (Type-1 Diabetes, Type-2 Diabetes), End User (Hospital & Clinics, Surgical Centers, Others), and By Region (North America, Europe, Asia-Pacific, And Rest Of The Wor...

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    Diabetic Nephropathy Market Summary

    As per Market Research Future Analysis, the Global Diabetic Nephropathy Market was valued at USD 2.30 Billion in 2023 and is projected to reach USD 4.29 Billion by 2032, growing at a CAGR of 6.25% from 2024 to 2032. The market growth is driven by the rising prevalence of diabetes, with an estimated 537 million individuals affected globally, expected to rise to 783 million by 2045. The increasing incidence of diabetic nephropathy, particularly in type-2 diabetes patients, is a significant factor contributing to market expansion. The market is characterized by advancements in treatment options and diagnostic methods, with hospitals and clinics being the primary end-users.

    Key Market Trends & Highlights

    Key trends influencing the Diabetic Nephropathy Market include rising diabetes prevalence and advancements in treatment options.

    • Diabetes caused 6.7 million fatalities in 2021, highlighting the urgent need for effective treatments.
    • Type-2 diabetes accounts for over 90% of diabetes diagnoses, significantly impacting nephropathy cases.
    • North America held the largest market share in 2022, driven by healthcare infrastructure and patient awareness.
    • FDA approvals for new medications, such as Bayer's Kerendia, are enhancing treatment options for diabetic nephropathy.

    Market Size & Forecast

    2023 Market Size USD 2.30 Billion
    2024 Market Size USD 2.49 Billion
    2032 Market Size USD 4.29 Billion
    CAGR (2024-2032) 6.25%

    Major Players

    Key players include Novartis AG, Merck & Co., Inc., Abbott Laboratories, Sanofi, Eli Lilly and Company, Reata Pharmaceuticals, Inc., Bayer AG, AbbVie, Inc., AstraZeneca, and Mitsubishi Tanabe Pharma Corporation.

    Diabetic Nephropathy Market Trends

      • Rising Prevalence of Diabetic Patients to Boost the Market Growth

    There are numerous symptoms of diabetic nephropathy, but the most common is diabetes mellitus. End-stage renal failure is 10 times more common in people with diabetes mellitus. For instance, International Diabetes Federation 2022 estimates that diabetes was a cause of 6.7 million fatalities in 2021. Along with that, 1 in 10 individuals (20 to 79 years old) have diabetes, which affects 537 million people. By 2030, it is expected to reach 643 million, and by 2045, it will reach 783 million. Similarly, according to the International Diabetes Federation (IDF), 40% of diabetics may experience kidney failure in its ultimate stages.

    Furthermore, about 80% of end-stage renal failure is caused by diabetes and hypertension, either together or individually.

    The introduction of new medicine for diabetic nephropathy in developing nations and the drug approvals by the FDA is offering a remunerative opportunity to the market. Due to an increase in both temporary and permanent chronic heart disease, hypertensive heart attacks, and diabetic nephropathy, angiotensin-converting enzyme inhibitors are frequently utilized. Thus, it stimulates market expansion.

    The increasing prevalence of diabetes globally is expected to drive a corresponding rise in diabetic nephropathy cases, necessitating enhanced healthcare strategies and innovative treatment options.

    Centers for Disease Control and Prevention (CDC)

    Diabetic Nephropathy Market Drivers

    Aging Population

    The aging global population is contributing to the expansion of the Global Diabetic Nephropathy Market Industry. As individuals age, the risk of developing chronic conditions, including diabetes and its complications, increases. The United Nations projects that by 2050, the number of people aged 60 years and older will double, reaching approximately 2.1 billion. This demographic shift is expected to result in a higher incidence of diabetic nephropathy, as older adults are more susceptible to kidney disease. Consequently, healthcare systems will need to adapt to this growing demand for nephropathy management, further propelling market growth.

    Market Growth Projections

    The Global Diabetic Nephropathy Market Industry is poised for substantial growth, with projections indicating an increase from 2.49 USD Billion in 2024 to 5.15 USD Billion by 2035. This growth trajectory reflects a compound annual growth rate (CAGR) of 6.82% from 2025 to 2035. The market dynamics are influenced by various factors, including the rising prevalence of diabetes, advancements in treatment options, and increased awareness regarding kidney health. As these elements converge, the market is likely to witness significant developments, shaping the future landscape of diabetic nephropathy management.

    Rising Prevalence of Diabetes

    The increasing prevalence of diabetes globally serves as a primary driver for the Global Diabetic Nephropathy Market Industry. According to the World Health Organization, the number of individuals diagnosed with diabetes has risen significantly, with estimates suggesting that by 2030, approximately 578 million people will be affected. This growing diabetic population is likely to lead to a corresponding rise in diabetic nephropathy cases, as diabetes is a leading cause of chronic kidney disease. Consequently, the demand for effective treatments and management strategies is expected to surge, contributing to the market's projected growth from 2.49 USD Billion in 2024 to 5.15 USD Billion by 2035.

    Regulatory Support and Funding

    Support from regulatory bodies and increased funding for diabetes-related research are bolstering the Global Diabetic Nephropathy Market Industry. Governments and health organizations are recognizing the need for enhanced research and development in diabetic nephropathy treatments. Initiatives such as the National Institutes of Health's funding for kidney disease research are indicative of this trend. Such support not only encourages innovation but also facilitates the development of new therapies and management strategies, ultimately contributing to the market's expansion as more effective solutions become available.

    Advancements in Treatment Options

    Innovations in treatment modalities for diabetic nephropathy are propelling the Global Diabetic Nephropathy Market Industry forward. Recent developments in pharmacotherapy, including the introduction of SGLT2 inhibitors and GLP-1 receptor agonists, have shown promise in delaying the progression of kidney disease in diabetic patients. These advancements not only improve patient outcomes but also enhance the quality of life for those affected. As healthcare providers increasingly adopt these novel therapies, the market is likely to experience substantial growth, with a compound annual growth rate (CAGR) of 6.82% projected from 2025 to 2035, reflecting the ongoing commitment to improving diabetic nephropathy management.

    Growing Awareness and Screening Initiatives

    Heightened awareness regarding diabetic nephropathy and its complications is fostering growth in the Global Diabetic Nephropathy Market Industry. Public health campaigns and educational initiatives aimed at both healthcare professionals and patients are emphasizing the importance of early detection and management of kidney disease. For instance, organizations such as the National Kidney Foundation are actively promoting screening for kidney function in diabetic patients. This increased awareness is likely to lead to earlier diagnosis and intervention, thereby expanding the patient base requiring treatment and management solutions, ultimately driving market growth.

    Market Segment Insights

    Diabetic Nephropathy Diagnosis Insights

    The diabetic nephropathy market segmentation, based on diagnosis, includes blood test, urine tests, imaging test, renal function testing, and kidney biopsy. The blood test segment held the majority share in 2022 in respect to the diabetic nephropathy market revenue. This is primarily owing to the rising prevalence of patients suffering from diabetes. Therefore, increasing chronic diseases such as obesity, and diabetes, have increased the demand for blood tests.

    July 2021: FDA approved Bayer AG's (Germany) Kerendia (finerenone) tablets to reduce the risk of decreasing kidney function, kidney failure, non-fatal heart attacks, cardiovascular death, and hospitalization due to heart failure in adults with chronic kidney disease associated with type 2 diabetes

    Diabetic Nephropathy Treatment Insights

    The diabetic nephropathy market segmentation, based on treatment, includes medication, kidney dialysis, and transplant. The medication segment dominated the market in 2022 in respect to the diabetic nephropathy market. This is attributed to the increasing number of chronic diseases such as obesity, diabetes, and other chronic illness that have increased the demand for medications.

    April 2021: ClinicalTrials.gov, Boehringer Ingelheim (Germany) registered for a phase 2 clinical trial to study the efficacy of BI 685509 against diabetic nephropathy. The aim is to study the efficacy of the medicine for kidney function improvement

    Diabetic Nephropathy Indication Insights

    The diabetic nephropathy market segmentation, based on indication includes type-1 diabetes and type-2 diabetes. Type-2 diabetes held the largest market share in 2022 with respect to the diabetic nephropathy market revenue. This is attributed to the high prevalence of Diabetic Nephropathy (DN) cases in adults aged 20 and older with type 2 diabetes worldwide. More than 90% of diabetes diagnoses are type 2, and the number of persons with type 2 diabetes is increasing, though more quickly in low- and middle-income nations than in high-income nations.

    Thus, the rising incidence of diabetes type-2 patients may result in diabetic nephropathy which consequently promotes the neuropathic pain market.

    May 2021:Novartis (Switzerland) signed a collaboration agreement and option to acquire Cellerys, a Zurich-based startup researching therapy to fight multiple sclerosis

    Diabetic Nephropathy End User Insights

    The diabetic nephropathy market segmentation, based on end user includes hospital & clinics, surgical centers, and others. The hospital & clinics held the largest market share in 2022 with respect to the diabetic nephropathy market revenue. Hospital & clinics have the highest market share as chronic kidney disease has become common across the globe and people suffering from chronic kidney disease have an increased risk of health complications. Based on one of the research articles from PLOS Medicine, adults suffering from chronic kidney disease have a higher hospitalization rate than the general population getting hospitalized.

    This eventually increases the use of drugs for treatment from hospital & clinics.

    January 2021: Pharma Foods International Co. Ltd. (Japan) entered into an exclusive licensing agreement with Mitsubishi Tanabe Pharma Corporation (Japan) to develop a candidate antibody to treat autoimmune diseases

    September 2019: Janssen Pharmaceuticals, Inc. (Belgium) announced the approval for Invokana (canagliflozin) by the US Food and Drug Administration (FDA) for reducing the progression of diabetic nephropathy heart failure chances in patients with type 2 diabetes and diabetic kidney disease

    Figure 2: Diabetic Nephropathy Market, by End User, 2022 & 2032 (USD Billion)

    Get more detailed insights about Diabetic Nephropathy Market Research Report - Forecast to 2032

    Regional Insights

    By region, the study segments the market into North America, Europe, Asia-Pacific, and the Rest of the World. North America diabetic nephropathy held the largest market share in 2022. This is attributed to the increase in the prevalence of diabetic nephropathy, health care infrastructure, and increased use of combination drugs, as well as an increase in diabetic patients’ awareness of diabetic nephropathy.

    Further, the major countries studied are: The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.

    Figure 3: Diabetic Nephropathy Market Share (%) By Region 2022

    Diabetic Nephropathy Market Share (%) By Region 2022

    Source: Secondary Research, Primary Research, Market Research Future Database and Analyst Review

    Europe diabetic nephropathy market accounts for the second-largest market share due to the rising government and pharmaceutical organization efforts to raise awareness of kidney disease as well as the existence of generic manufacturers are also boosting the market growth. Further, the Germany diabetic nephropathy market held the largest market share, and the UK diabetic nephropathy market was the fastest-growing market in the European region.

    The Asia-Pacific Diabetic Nephropathy market is expected to grow at a significant growth rate during the forecast period. This is due to the increased healthcare spending, increased market awareness of new diabetic drugs, and increase in the number of hospitals are factors expected to boost the market over the forecast period. Moreover, China diabetic nephropathy market held the largest market share, and the India diabetic nephropathy market was the fastest-growing market in the Asia-Pacific region. Hence, Asia-Pacific is anticipated to register the highest growth rate over the forecast period from 2024–2032.

    Key Players and Competitive Insights

    Major market players are spending a lot of money on R&D to increase their product lines, which will help the diabetic nephropathy market grow even more. Market participants are also taking a range of strategic initiatives to grow their worldwide footprint, including new product launches, contractual agreements, mergers and acquisitions, increased investments, and collaboration with other organizations. Competitors in the diabetic nephropathy industry must offer cost-effective items to expand and survive in an increasingly competitive and rising market environment.

    One of the primary business strategies adopted by manufacturers in the diabetic nephropathy industry to benefit clients and expand the diabetic nephropathy market sector is to manufacture locally to reduce operating costs.

    AstraZeneca (UK) is a leading biopharmaceutical company. It focuses on developing and commercializing prescribed medicines. It has three main therapy areas, namely, cardiovascular, and metabolic disease (CVMD), oncology, and respiratory. It is also active in areas such as neuroscience autoimmunity and infection. Their product portfolio includes medications in the field of oncology, cardiovascular, renal & metabolism, and respiratory diseases, among others.

    For instance, in 2021, AstraZeneca’s Farxiga (dapagliflozin), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, has been approved in the US to reduce the risk of sustained estimated glomerular filtration rate (eGFR) decline, end-stage kidney disease (ESKD), cardiovascular (CV) death and hospitalization for heart failure (hHF) in adults with chronic kidney disease (CKD) at risk of progression.

    Key Companies in the Diabetic Nephropathy Market market include

    Industry Developments

    January 2023: Boehringer Ingelheim (Germany) and Eli Lilly and Company (US) announced that US Food and Drug Administration (FDA) approved a supplemental New Drug Application (sNDA) for Jardiance (empagliflozin) investigating a potential new indication to lower blood sugar along with diet and exercise in children 10 years and older with type 2 diabetes. These tablets have been investigated as a possible therapy to reduce the chance of cardiovascular death and kidney disease progression in adults with chronic kidney disease.

    August 2022: Bayer (Germany) launched Finerenone under the brand name Kerendia in India. Finerenone is a first-in-class non-steroidal, selective mineralocorticoid receptor antagonist indicated for patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D)

    April 2021: AstraZeneca (UK) Farxiga has been approved in the US to treat chronic kidney disease in patients at risk of progression with and without type-2 diabetes

    Future Outlook

    Diabetic Nephropathy Market Future Outlook

    The Global Diabetic Nephropathy Market is poised for growth at 6.82% CAGR from 2024 to 2035, driven by increasing diabetes prevalence, advancements in treatment options, and rising awareness.

    New opportunities lie in:

    • Develop innovative drug delivery systems to enhance patient compliance and treatment efficacy.
    • Invest in telehealth solutions for remote monitoring and management of diabetic nephropathy patients.
    • Explore partnerships with biotechnology firms to accelerate research on regenerative therapies.

    By 2035, the market is expected to exhibit robust growth, reflecting advancements in treatment and increased patient engagement.

    Market Segmentation

    Diabetic Nephropathy End User Outlook

    • Hospital & Clinics
    • Surgical Centers
    • Others

    Diabetic Nephropathy Regional Outlook

    North America
    • US
    • Canada

    Diabetic Nephropathy Diagnosis Outlook

    • Blood Test
    • Urine Test
    • Imaging Test
    • Renal Function Testing
    • Kidney Biopsy

    Diabetic Nephropathy Treatment Outlook

    Medication
    • Angiotensin-Converting Enzyme (ACE) Inhibitors
    • Angiotensin II Receptors Blockers
    • Antioxidant Inflammation Modulator
    • Calcium Channel Blockers
    • Diuretics
    • Others

    Diabetic Nephropathy Indication Outlook

    • Type-1 Diabetes
    • Type-2 Diabetes

     Diabetic Nephropathy Treatment Outlook

    Medication
    • Angiotensin-Converting Enzyme (ACE) Inhibitors
    • Angiotensin II Receptors Blockers
    • Antioxidant Inflammation Modulator
    • Calcium Channel Blockers
    • Diuretics
    • Others

     Diabetic Nephropathy Indication Outlook

    • Type-1 Diabetes
    • Type-2 Diabetes

    Report Scope

    Report Attribute/Metric Details
    Market Size 2023 USD 2.30 billion
    Market Size 2024 USD 2.49 billion
    Market Size 2032 USD 4.29 billion
    Compound Annual Growth Rate (CAGR) 6.25% (2024-2032)
    Base Year 2023
    Forecast Period 2024-2032
    Historical Data 2019-2022
    Forecast Units Value (USD Billion)
    Report Coverage Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
    Segments Covered Diagnosis, Treatment, Indication, End User and Region
    Geographies Covered North America, Europe, Asia Pacific, and Rest of the World
    Countries Covered The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil
    Key Companies Profiled Novartis AG (Switzerland), Merck & Co., Inc. (US), Abbott Laboratories (US), Sanofi (France), Eli Lilly and Company (US), Reata Pharmaceuticals, Inc. (US), Bayer AG (Germany), AbbVie, Inc. (US), AstraZeneca (UK), Mitsubishi Tanabe Pharma Corporation (Japan)
    Key Market Opportunities Increasing number of geriatric populations
    Key Market Dynamics Rising prevalence of diabetic patients Rising prevalence of hypertension

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    How much is the Diabetic Nephropathy Market?

    The diabetic nephropathy market is anticipated to reach USD 4.29 billion at a CAGR of 6.25% during the forecast period of 2024 to 2032

    How Big is the US Diabetic Nephropathy Market?

    The US diabetic nephropathy market share is 35-40% during the forecast period of 2024 to 2032

    What is the growth rate of the Diabetic Nephropathy market?

    The diabetic nephropathy market is expected to register a CAGR of 6.25% during the forecast period of 2024 to 2032.

    Which region held the largest market share in the Diabetic Nephropathy market?

    North America held the largest market share in the diabetic nephropathy market

    Who are the key players in the Diabetic Nephropathy market?

    Novartis AG (Switzerland), Merck & Co., Inc. (US), Abbott Laboratories (US), Sanofi (France), Eli Lilly and Company (US)

    Which indication segment led the Diabetic Nephropathy market?

    The Type-2 diabetes led the diabetic nephropathy market

    Which end user had the largest market share in the Diabetic Nephropathy market?

    The hospital & clinics end user led the diabetic nephropathy market

    Diabetic Nephropathy Market Research Report - Forecast to 2032 Infographic
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