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Dental Bone Graft Substitutes Market Analysis

ID: MRFR//5852-HCR | 100 Pages | Author: Rahul Gotadki| November 2024

The dental bone graft substitutes market is witnessing significant growth due to the rising prevalence of dental conditions like periodontal diseases and tooth loss, along with increasing awareness about dental health.


Market Drivers: Several factors are driving the growth of the dental bone graft substitutes market. These include the growing aging population, increasing dental implant procedures, advancements in dental biomaterials, and the rising demand for minimally invasive dental treatments.


Types of Dental Bone Graft Substitutes: The market offers various types of dental bone graft substitutes, including synthetic bone grafts, xenografts, allografts, and autografts. Each type has its unique properties and applications, catering to different patient needs and preferences.


Technological Advancements: Continuous advancements in dental biomaterials and tissue engineering are enhancing the effectiveness and safety of dental bone graft substitutes. Innovations in materials science and manufacturing technologies are leading to the development of biocompatible and osteoconductive grafting materials.


Market Challenges: Despite its growth prospects, the dental bone graft substitutes market faces challenges such as high treatment costs, limited reimbursement policies, regulatory hurdles, and the risk of post-operative complications. Addressing these challenges is crucial for ensuring market sustainability and growth.


Key Market Players: The market is characterized by the presence of several key players, including dental implant manufacturers, biomaterial companies, and dental clinics. Companies like Straumann Group, Zimmer Biomet Holdings Inc., DENTSPLY SIRONA Inc., and Geistlich Pharma AG are leading the way in developing innovative dental bone graft substitutes.


Market Trends: Key trends in the dental bone graft substitutes market include the growing adoption of CAD/CAM technology for customized graft fabrication, the rise of minimally invasive dental procedures, the increasing use of growth factors and stem cells in grafting materials, and the emergence of 3D printing technology for manufacturing patient-specific grafts.


Market Opportunities: The dental bone graft substitutes market presents significant opportunities for growth and innovation. These include expanding market penetration in emerging economies, developing novel grafting materials with improved biocompatibility and osteoinductivity, and leveraging digital dentistry technologies for enhanced treatment planning and outcomes.


Regulatory Landscape: The regulatory landscape surrounding dental bone graft substitutes varies by region, with different countries having their own regulations governing the approval and marketing of dental biomaterials. Companies operating in this market must navigate through complex regulatory frameworks to ensure compliance and market access.


Market Segmentation: The dental bone graft substitutes market can be segmented based on type, material, application, and end-user. Understanding the unique needs and preferences of different patient demographics and dental specialties is essential for effectively targeting market segments and maximizing growth opportunities.


Market Dynamics: The dental bone graft substitutes market is characterized by intense competition, rapid technological advancements, and a strong focus on research and development. Market dynamics are influenced by factors such as changing consumer preferences, shifting healthcare policies, and evolving treatment guidelines.


Future Outlook: The future of the dental bone graft substitutes market looks promising, with continued investments in research and development, increasing adoption of digital dentistry technologies, and growing demand for minimally invasive dental treatments. As dental healthcare continues to evolve, the demand for innovative bone graft substitutes is expected to rise, driving market growth and expansion.

Global Dental Bone Graft Substitutes Market Overview


The dental bone graft substitutes market size was valued at USD 1.1 billion in 2023 and is projected to grow from USD 1.2 Billion in 2024 to USD 1.73 billion by 2032, exhibiting a compound annual growth rate (CAGR) of 4.68% during the forecast period (2024 - 2032). The growing number of dental visits and use of synthetic and biocompatible grafts in dental procedures are just a few market drivers that are propelling the market. 


Dental Bone Graft Substitutes Market Overview1


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Dental Bone Graft Substitutes Market Trends



  • Growing prevelance of dental diorders to aid market growth


Most oral health conditions can be treated when young and are largely preventable. Dental caries (tooth decay), periodontal diseases, tooth loss, and oral cancers account for most cases. Orofacial clefts, noma (a severe gangrenous illness that begins in the mouth and primarily affects children), and oro-dental trauma are additional oral conditions of public health significance. According to the WHO Oral Health Status Report (2022), nearly 3.5 billion people worldwide suffer from oral diseases, with three out of every four individuals residing in middle-income nations. Five hundred fourteen million children worldwide suffer from primary tooth decay, while 2 billion adults are thought to have permanent tooth decay. With increasing urbanization and changes in livable conditions, the prevalence of major oral diseases is rising globally. This is primarily caused by inadequate exposure to fluoride (found in toothpaste and water supplies), accessibility to and affordability of foods high in sugar, and a lack of access to oral health care services in the community. Products that contribute to oral health problems and other NCDs are increasingly consumed due to the marketing of sugar-rich foods and beverages and tobacco and alcohol. Such a growing prevalence of various dental disorders is expected to drive the market CAGR.


Figure 1: Prevalence of total dental caries and untreated dental caries in primary or permanent teeth among youth aged 2–19 years, by age: United States, 2015–2016Prevalence of total dental caries and untreated dental caries in primary or permanent teeth among youth aged 2–19 years, by age: United States, 2015–2016


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


The rising geriatric population is also a key market driver as older adults are more susceptible to dental disorders. According to the US Census, there will be 98 million US adults who are 65 or older in 2060 or 24% of the entire population. It has been estimated that the prevalence of dental disorders is higher among older people. According to the Centers for Disease Control and Prevention, one in five adults (or 96% of adults 65 years of age and older) have untreated tooth decay. Nearly one in five adults 65 and older has lost every tooth. Adults 75 and older (26%) experience twice as many complete tooth losses as those 65 to 74 (13%). Since one out of every four dental implants requires this well-accepted procedure for reversing dental bone loss, this presents an opportunity for dental bone graft substitutes. Thus, this aspect is expected to accelerate Dental Bone Graft Substitutes market revenue globally.


Moreover, a growing research study to find an alternative for a dental bone graft is also anticipated to surge the market growth during the forecast period. Research and development in materials, design, and fabrication technologies have advanced over time to produce successful and durable dental implants to replace missing teeth. Due to improvements in dental implantology and the increasing need to repair craniofacial bony defects, the use of bone grafts and replacements has significantly increased in dentistry in recent years. According to current data, 2.2 million bone graft procedures are estimated to be carried out annually globally, with the cost of those procedures expected to reach USD 664 million by 2021. Additionally, it is predicted that the number of surgical techniques for treating bony defects will increase by about 13% annually.


Dental Bone Graft Substitutes Market Segment Insights


Dental Bone Graft Substitutes Type Insights


The Dental Bone Graft Substitutes market segmentation, based on type, includes allograft, xenograft, and alloplast. The xenograft segment held the majority share in 2022 in the Dental Bone Graft Substitutes market data. Xenografts are obtained from pigs (porcine) or cows (bovine) and are sterilised before being carefully cleaned and prepared for implantation into the human body. In dentistry, deproteinized bovine bone is the most typical source of xenograft materials. The strategic actions taken by market participants are also assisting in the market's expansion.


March 2022:Fredun Pharmaceuticals permission to produce Xenografts for a range of dental and orthopaedic surgical appliances form the Central Drugs Standard Control Organization (COSCO), India. The Company plans to expand its reach within the dental community in India by doing this. Due to the increased use of grafts by doctors, the company is expanding its product line with this new addition in order to capitalise on the expanding market.


Figure 2: Dental Bone Graft Substitutes Market, by Type, 2023 & 2032 (USD Billion)


Dental Bone Graft Substitutes Market, by Type


Source: Secondary Research, Primary Research, MRFR Database and Analyst Review


Dental Bone Graft Substitutes Application Insights


The Dental Bone Graft Substitutes market segmentation, based on application, includes Ridge augmentation, sinus lift, socket preservation, and periodontal defect. The ridge augmentation segment dominated the market growth in 2022 and is projected to be the faster-growing segment during the forecast period, 2022-2030. The growth of this market is being driven by an increase in dental implant surgeries and public awareness of the importance of oral health care. Additionally, the burden of dental diseases is rising, and technological developments in dentistry are supporting segment growth.


Dental Bone Graft Substitutes End User Insights


The Dental Bone Graft Substitutes market data, based on end user, includes dental clinics and hospitals. The dental clinics segment dominated the Dental Bone Graft Substitutes market revenue in 2022 and is projected to be the faster-growing segment during the forecast period, 2022-2030. A growing number of dental clinics coupled with the rising prevalence of dental diseases are among the key factors propelling the growth of this segment. Moreover, due to their convenience and easy accessibility of surgeons, dental clinics are becoming more and more popular as the number of dental graft surgeries each year increases.


Dental Bone Graft Substitutes Regional Insights


By region, the study provides the market insights for dental bone graft substitutes into North America, Europe, Asia-Pacific and Rest of the World. North America Dental Bone Graft Substitutes market accounted for USD 0.4 billion in 2022 with a share of around 45.80% and is expected to exhibit a significant CAGR growth during the study period. The main factors influencing the region's growth are rising healthcare costs, increased awareness of commercially available advanced products, and accessibility to an advanced healthcare system. Fuether, growing prevelance of dental disease is also playing a pivotal factor in the markets growth. According to the Center for Disease Control and Prevention, in the United States, untreated tooth decay affects 26% of adults.


Further, the major countries studied in the market report for dental bone graft substitutes are: The U.S, Canada, Germany, France, UK, Italy, Spain, China, Japan, India, Australia, South Korea, and Brazil.


Figure 3: DENTAL BONE GRAFT SUBSTITUTES MARKET SHARE BY REGION 2022 (%) 


DENTAL BONE GRAFT SUBSTITUTES MARKET SHARE BY REGIONSource: Secondary Research, Primary Research, MRFR Database and Analyst Review


Europe Dental Bone Graft Substitutes market accounts for the second-largest market share. The demand for medical and dental tourism is on the rise, dental diseases are becoming more prevalent, and dental technology is advancing, which are all contributing factors to the growth in this area. The market is expanding due to the rising burden of dental diseases. Moreover, UK Dental Bone Graft Substitutes market held the largest market share, and the Germany Dental Bone Graft Substitutes market was the fastest growing market in the region.


Asia Pacific Dental Bone Graft Substitutes Market is expected to grow at the fastest CAGR from 2022 to 2030. An increase in medical tourism and government initiatives are two factors that have contributed to the growth of the market in this region. Additionally, the region's growing elderly population is raising the risk of dental issues is also aiding the market growth. Further, the China Dental Bone Graft Substitutes market held the largest market share, and the India Dental Bone Graft Substitutes market was the fastest growing market in the region.


Dental Bone Graft Substitutes Key Market Players & Competitive Insights


Major market players are investing in R&D to expand their product lines, which will fuel the growth of the Dental Bone Graft Substitutes market. Participants in the market are also undertaking various strategic initiatives to expand their footprint. Significant market developments include new product launches, mergers and acquisitions, contractual agreements, increased investments, and collaboration with other players.


One of the primary business strategies adopted by manufacturers in the Dental Bone Graft Substitutes industry is introducing new products in the market. In recent years, Dental Bone Graft Substitutes Industry has been adopted in many hospitals and healthcare institutes. The Dental Bone Graft Substitutes market major player such as Orthogen, LLC (US), LifeNet Health (US), Dentium (South Korea), Zimmer Biomet Dental (US), Medtronic Plc (Ireland), Institut Straumann AG (Switzerland), Dentsply Sirona (US), Geistlich Pharma AG (Switzerland), and Biohorizons Iph Inc. (US) are conducting research & development activities.


LifeNet Health is a pioneer in regenerative medicine and the most reputable provider of transplant solutions in the world, offering everything from organ procurement to bio-implants and cellular therapies. In October 2022, LifeNet Health displayed the most cutting-edge allograft biologics for fusion during that time in the North American Spine Society (NASS) 2022 Annual Meeting was held in Chicago from October 12–14.


Zimmer Biomet develops new methods to treat conditions that affect or injure the bones, joints, and supporting soft tissues. In March 2022, Biocomposites has entered into a multi-year agreement with Zimmer Biomet, for distributing genex Bone Graft Substitute with its new mixing system and delivery options in the U.S. orthopaedic market.


Key Companies in the Dental Bone Graft Substitutes market includes




  • Orthogen LLC (US)




  • LifeNet Health (US)




  • Dentium (South Korea)




  • Zimmer Biomet Dental (US)




  • Medtronic Plc (Ireland)




  • Institut Straumann AG (Switzerland)




  • Dentsply Sirona (US)




  • Geistlich Pharma AG (Switzerland)




  • Biohorizons Iph Inc. (US), among others




Dental Bone Graft Substitutes Industry Developments


March 2022:A pioneer in regenerative medicine polymer technology, Molecular Matrix, Inc. (MMI), announced the full release of its Osteo-P Synthetic Bone Graft Substitute (BGS) for use in the musculoskeletal system..


January 2019:Bioventus launched OSTEOMATRIX+, a new generation biphasic bone graft for use in bone remodelling in a range of orthopaedic and spine applications. A moldable alternative to bone grafts, OSTEOMATRIX+ is made of bovine collagen and biphasic hydroxyapatite/ß-tricalcium phosphate granules to create a stable, porous scaffold and maintain osteoconductivity throughout the bone remodelling process.


Dental Bone Graft Substitutes Market Segmentation


Dental Bone Graft Substitutes Type Outlook (USD Billion, 2018-2030)




  • Allograft




  • Xenograft




  • Alloplast




Dental Bone Graft Substitutes Application Outlook (USD Billion, 2018-2030)




  • Ridge Augmentation




  • Sinus Lift




  • Socket Preservation




  • Periodontal Defect




Dental Bone Graft Substitutes End-User Outlook (USD Billion, 2018-2030)




  • Dental Clinics




  • Hospitals




Dental Bone Graft Substitutes Regional Outlook (USD Billion, 2018-2030)




  • North America






  • US




  • Canada






  • Europe






  • Germany




  • France




  • UK




  • Italy




  • Spain




  • Rest of Europe






  • Asia-Pacific




    • China




    • Japan




    • India




    • Australia




    • South Korea




    • Australia




    • Rest of Asia-Pacific






  • Rest of the World




    • Middle East




    • Africa




    • Latin America





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