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    Cholic acid Market

    ID: MRFR/HC/6619-CR
    70 Pages
    Rahul Gotadki
    July 2019

    Cholic Acid Market Research Report Information by Application ( Emulsifier, Detergents, Medicines, Organic acid) Method (Folding ethyl acetate separation method, Folding ethanol crystallization method, Folding animal extraction, Others) Region (Europe, Asia-Pacific, Americas and the Middle East & Africa) - Forecast till 2035

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    Cholic acid Market Infographic
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    Cholic acid Market Summary

    As per Market Research Future Analysis, the Cholic Acid Market is projected to reach USD 265 million, growing at a CAGR of 7.4% from 2023 to 2032. Cholic acid, produced by the liver from cholesterol, plays a crucial role in fat digestion and is essential in manufacturing ursodeoxycholic acid, a treatment for gallbladder stones and liver diseases. The market is driven by rising obesity rates, increasing cases of gallbladder cancer, and a growing geriatric population. However, stringent regulations pose challenges to market growth. The COVID-19 pandemic has also impacted the market, necessitating adaptations in business operations.

    Key Market Trends & Highlights

    The Cholic Acid Market is witnessing significant growth due to various health-related factors.

    • Gallbladder cancer cases reached approximately 220,000 globally in 2018, driving demand for cholic acid.
    • The market is expected to grow at a CAGR of 8.47% during the forecast period.
    • Europe holds the largest market share at 39.5%, attributed to a high concentration of manufacturers.
    • The Asia-Pacific region is seeing increased demand due to rising obesity rates in countries like India and China.

    Market Size & Forecast

    Market Size USD 265 Million
    Forecast CAGR 7.4% (2023-2032)
    Largest Regional Market Share Europe (39.5%)

    Major Players

    Key players include Alchem International Ltd, Zhejiang Yongning Pharmaceutical, Showa Denko KK, Erregierre SpA, Retrophin, Inc., and PharmaZell GmbH.

    Cholic acid Market Trends

    One of the significant factors behind the growth of the Cholic acid market is the increase in the cases of gallbladder cancer. And according to the studies, gallstones are the reason behind the development of the market. This study revealed that almost 2,20,00 new cases of people suffering from gallbladder cancer were diagnosed worldwide in the year 2018. This high rate of gall cancer cases can be correlated with gallstones too. Therefore, the growing rate of gallbladder cancer has ultimately led to an increase in the usage of colic acid.

    The entire scenario has made the market grow at a favorable rate. The market is expected to grow at a similar place due to changing lifestyles, obesity, and similar factors leading to liver diseases and gall bladder conditions.

    Regulatory Implications

    Few factors affect the cholic acid market analysis, but the one that has been affecting the most is the regulations and laws laid down by various regulatory bodies, governments, and local bodies for the wise usage of cholic acid. These are indeed strict and stringent and holds back the market from growing further. The regulations are implemented because of the use on the human body. Though they have been found very useful in treating liver and gallbladder conditions, there are still some contraindications that negatively affect the human body.

    The regulatory bodies need to make sure that colic acid is done in an appropriate manner and that it does not cause any harm to any human being or even the environment. No doubt the regulations are structured, but there is a fire need for such stringent rules to make cholic acid function be implemented in a wiser way.

    Cholic Acid Market Segmentation 

    The market can be divided based on two factors. They are:

    Based on application: Based on application, the market can further be subdivided into the following categories:

    Emulsifier Detergents Medicines Organic acid

    Based on method: Based on the technique, the market can further be classified into the following subcategories:

    Folding ethyl acetate separation method Folding ethanol crystallization method Folding animal extraction Others

    Based on these two broad classifications of the market, each of them has a unique market value. Based on the application, the Medicines segment holds a significant part in the cholic acid market. With its widespread use in various kidney diseases, it has gained popularity across the world.

    Cholic Acid Market Regional Analysis

    Based on the regions, the cholic acid market has the following subtypes:

    Americas Europe The Middle East and Africa Asia- Pacific

    Europe holds the most significant share in the market with a value of almost 39.5% of the total stake.  The dominance of the region in the market is primarily due to substantial manufacturers in the area.

    The Asia Pacific also holds a significant share of the ursodeoxycholic acid market. This is because of the increase in ten obese populations the countries like India and China. Obesity comes with an increased risk of gall stems and, after that, gallbladder cancer.

    The cholic acid market expects to attend a CAGR of 8.47% during the forecast period. The American region has two central areas that include North America and Latin America. Increased gall bladder stones are likely to be a significant factor in the increased growth of the market.

    The Middle East and Africa have the most negligible share in the cholic acid market but expect a steady increase due to the increased geriatric population in the region.

    Cholic Acid Market Key Players

    The major players are: 

    Alchem International Ltd (US) Zhejiang Yongning Pharmaceutical (Zhejiang) Showa Denko KK (Japan) Erregierre SpA (Italy) Retrophin, Inc. (the US) Fujimoto Chemicals (Japan) PharmaZell GmbH (Germany) Panjin Hengchanglong Pharmaceutical (China) Kinsy SL (Spain) Istituto Biologico Chemioterapico SpA (Italy) Daewoong Bio, Inc. (South Korea) Suzhou Tianlu Biopharmaceuticals Co. Ltd (China, Dipharma Francis SRL (Italy) New Zealand Pharmaceuticals Limited (New Zealand)  Industria Chimica Emiliana SRL (Italy)

    All these significant players in the market have been working in a strategic and a planned manner. Various collaborations, acquisitions, and mergers amongst themselves have taken the call to the heights of success. They have also been leading the market as idols for the new entrants. It is not just for the growth of themself but also for the development of the market as a whole.

    Recent advancements

    Here are few recent advancements made in the cholic acid market:

    In April 2016, a significant stake created by the bile business was acquired by PharmaZell GmbH from Fayan international to expand its business horizons. New Zealand pharmaceutical limited was acquired by Archer’s capital in July 2016 to increase its share in the ursodeoxycholic acid market. Dipharma Francis SRL acquired Kalexsyn Inc. The motive was to offer services in the field of biotechnology and pharma. Advancements in the market are being made to ensure the market strictly follows the regulations laid down by the governments of various regions. The use of colic acid in industries like detergents and emulsifiers is being studied in depth. The main aim is to increase its usage in various end-use industries to increase the global market. 

    Report overview

    The report provided includes all the significant and small aspects required by an organization to do well and even combat losses during the Covid times. Starting from the overview of the cholic acid market to analysis based on the Covid impact, it also includes the market dynamics of the cholic acid market. The market segmentation based on method type and application is also included in the report. The market analysis based on five different regions is also provided with the report.

    The report's lap gives the details about the major players in the market and various strategies they have been following for the market's growth. The latest developments in the market are also provided to move forward with the newest technology. The current market scenario and the ways that can be implemented to bring about growth are shared in a detailed manner—all the reports are prepared by analysts with expertise in the field and the industry experts.

    The global cholic acid market appears to be experiencing a notable shift towards increased demand driven by its applications in pharmaceuticals and dietary supplements, suggesting a growing recognition of its therapeutic potential.

    U.S. Food and Drug Administration (FDA)

    Cholic acid Market Drivers

    Market Growth Projections

    The Global Cholic Acid Market Industry is projected to experience substantial growth over the next decade. With a compound annual growth rate (CAGR) of 11.18% anticipated from 2025 to 2035, the market is expected to expand significantly. This growth is driven by various factors, including the rising demand for bile acid derivatives and the increasing applications in pharmaceuticals. The market size is forecasted to reach 328.3 USD Million by 2035, reflecting the growing recognition of cholic acid's therapeutic potential. These projections underscore the dynamic nature of the Global Cholic Acid Market Industry and its capacity to adapt to evolving market demands.

    Rising Demand for Bile Acid Derivatives

    The Global Cholic Acid Market Industry experiences a notable increase in demand for bile acid derivatives, which are essential for various pharmaceutical applications. As bile acids play a crucial role in digestion and metabolism, their derivatives are increasingly utilized in drug formulations. This trend is driven by the growing prevalence of metabolic disorders and liver diseases, which require effective treatment options. The market is projected to reach 102.3 USD Million in 2024, reflecting a robust growth trajectory. The rising awareness of the therapeutic potential of bile acids further propels this demand, indicating a promising outlook for the Global Cholic Acid Market Industry.

    Expansion of Pharmaceutical Applications

    The Global Cholic Acid Market Industry is significantly influenced by the expansion of pharmaceutical applications. Cholic acid is increasingly recognized for its role in drug development, particularly in the formulation of novel therapeutics. Its unique properties facilitate the solubilization of poorly soluble drugs, enhancing bioavailability and therapeutic efficacy. As pharmaceutical companies invest in research and development, the utilization of cholic acid in innovative drug formulations is expected to rise. This trend is anticipated to contribute to the market's growth, with projections indicating a market size of 328.3 USD Million by 2035, highlighting the potential of cholic acid in the pharmaceutical sector.

    Growing Interest in Natural and Organic Products

    The Global Cholic Acid Market Industry is witnessing a shift towards natural and organic products, driven by consumer preferences for health and wellness. Cholic acid, derived from natural sources, aligns with the increasing demand for clean-label ingredients in dietary supplements and functional foods. This trend is particularly prominent in regions where consumers prioritize transparency and sustainability in product sourcing. As manufacturers respond to this demand by incorporating cholic acid into their offerings, the market is likely to benefit from this growing interest. This shift towards natural products may further enhance the market's growth potential in the coming years.

    Increasing Research Activities and Clinical Trials

    The Global Cholic Acid Market Industry is bolstered by increasing research activities and clinical trials focusing on the therapeutic applications of cholic acid. Researchers are exploring its potential in treating various conditions, including metabolic disorders and liver diseases. The growing body of scientific literature and clinical evidence supports the efficacy of cholic acid in these applications, attracting interest from pharmaceutical companies. As more clinical trials are initiated, the market is expected to witness a surge in demand for cholic acid, further solidifying its position in the pharmaceutical landscape. This trend indicates a promising future for the Global Cholic Acid Market Industry.

    Technological Advancements in Production Processes

    Technological advancements in production processes are playing a pivotal role in shaping the Global Cholic Acid Market Industry. Innovations in extraction and synthesis methods have led to improved efficiency and cost-effectiveness in cholic acid production. These advancements not only enhance the quality of the final product but also contribute to sustainability by reducing waste and energy consumption. As manufacturers adopt these technologies, the overall supply chain becomes more robust, facilitating a steady supply of cholic acid to meet the growing demand. This trend is likely to support the market's expansion, particularly as production capabilities are optimized.

    Future Outlook

    Cholic acid Market Future Outlook

    The Cholic Acid Market is projected to grow at 11.18% CAGR from 2024 to 2035, driven by rising healthcare demands, advancements in pharmaceuticals, and increasing applications in dietary supplements.

    New opportunities lie in:

    • Develop innovative cholic acid derivatives for enhanced therapeutic applications.
    • Expand production capabilities to meet growing global demand in emerging markets.
    • Leverage digital marketing strategies to increase awareness and accessibility of cholic acid products.

    By 2035, the Cholic Acid Market is expected to achieve substantial growth, solidifying its position as a key player in the pharmaceutical industry.

    Market Segmentation

    Recent advancements

    • The use of colic acid in industries like detergents and emulsifiers is being studied in depth. The main aim is to increase its usage in various end-use industries to increase the global market. 
    • Advancements in the market are being made to ensure the market strictly follows the regulations laid down by the governments of various regions.
    • Dipharma Francis SRL acquired Kalexsyn Inc. The motive was to offer services in the field of biotechnology and pharma.
    • New Zealand pharmaceutical limited was acquired by Archer’s capital in July 2016 to increase its share in the ursodeoxycholic acid market.
    • In April 2016, a significant stake created by the bile business was acquired by PharmaZell GmbH from Fayan international to expand its business horizons.

    Cholic Acid Market Key Players

    • Industria Chimica Emiliana SRL (Italy)
    • New Zealand Pharmaceuticals Limited (New Zealand) 
    • Suzhou Tianlu Biopharmaceuticals Co. Ltd (China, Dipharma Francis SRL (Italy)
    • Daewoong Bio, Inc. (South Korea)
    • Istituto Biologico Chemioterapico SpA (Italy)
    • Kinsy SL (Spain)
    • Panjin Hengchanglong Pharmaceutical (China)
    • PharmaZell GmbH (Germany)
    • Fujimoto Chemicals (Japan)
    • Retrophin, Inc. (the US)
    • Erregierre SpA (Italy)
    • Showa Denko KK (Japan)
    • Zhejiang Yongning Pharmaceutical (Zhejiang)
    • Alchem International Ltd (US)
    • The use of colic acid in industries like detergents and emulsifiers is being studied in depth. The main aim is to increase its usage in various end-use industries to increase the global market. 
    • Advancements in the market are being made to ensure the market strictly follows the regulations laid down by the governments of various regions.
    • Dipharma Francis SRL acquired Kalexsyn Inc. The motive was to offer services in the field of biotechnology and pharma.
    • New Zealand pharmaceutical limited was acquired by Archer’s capital in July 2016 to increase its share in the ursodeoxycholic acid market.
    • In April 2016, a significant stake created by the bile business was acquired by PharmaZell GmbH from Fayan international to expand its business horizons.

    Cholic Acid Market Segmentation 

    • Organic acid
    • Medicines
    • Detergents
    • Emulsifier
    • Others
    • Folding animal extraction
    • Folding ethanol crystallization method
    • Folding ethyl acetate separation method

    Cholic Acid Market Regional Analysis

    • Asia- Pacific
    • The Middle East and Africa
    • Europe
    • Americas

    Report Scope

    Report Attribute/Metric Details
      Market Size   2032 : 265 Million
      CAGR   7.4% (2023- 2032)
      Base Year   2020
      Forecast Period   2023-2032
      Historical Data   2019
      Forecast Units    Value (USD Million)
      Report Coverage   Revenue Forecast, Competitive Landscape, Growth Factors, and Trends
      Segments Covered   By Region
      Geographies Covered   North America, Europe, Asia-Pacific, and Rest of the World (RoW)
      Key Vendors   Alchem International Ltd (US), Zhejiang Yongning Pharmaceutical (Zhejiang), Showa Denko KK (Japan), Erregierre SpA (Italy), Retrophin, Inc. (the US), Fujimoto Chemicals (Japan), PharmaZell GmbH (Germany), Panjin Hengchanglong Pharmaceutical (China), Kinsy SL (Spain), Istituto Biologico Chemioterapico SpA (Italy), Daewoong Bio, Inc. (South Korea), Suzhou Tianlu Biopharmaceuticals Co. Ltd (China, Dipharma Francis SRL (Italy)
      Key Market Opportunities   strategic alliances, mergers and acquisitions and new product developments
      Key Market Drivers ·  Increased geriatric population ·  Increase in the cases of gallbladder cancer

    Market Highlights

    Author
    Rahul Gotadki
    Assistant Manager

    He holds an experience of about 7+ years in Market Research and Business Consulting, working under the spectrum of Life Sciences and Healthcare domains. Rahul conceptualizes and implements a scalable business strategy and provides strategic leadership to the clients. His expertise lies in market estimation, competitive intelligence, pipeline analysis, customer assessment, etc. In addition to the above, his other responsibility includes strategic tracking of high growth markets & advising clients on the potential areas of focus they could direct their business initiatives

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    FAQs

    What is the predicted CAGR for the forecast period of 2023 to 2032?

    cholic acid market CAGR would be 7.4% during the forecast period.

    What is the projected valuation of the market?`

    The market by 2032 would grow up to USD 265 Million.

    What are the restraints of the market?

    The prevalence of gallbladder cancer, obesity, geriatric population, and regulatory policies can hold back the market.

    Which region would lead the market?

    Europe would lead the market with a 39.5% market share.

    Which region would be the fastest-growing in the global market?

    The Americas would be the fastest-growing region in the global market.

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