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Cerebrospinal Fluid Management Devices Companies

Cerebrospinal fluid (CSF) management devices are used in neurosurgical procedures to manage the flow and pressure of cerebrospinal fluid in and around the brain and spinal cord. These devices are crucial in the treatment of conditions such as hydrocephalus and other neurosurgical interventions.

Cerebrospinal Fluid Management Devices CompaniesLatest Cerebrospinal Fluid Management Devices Companies Update



  • July 2023: Anuncia Medical Inc., an organization dedicated to the development of innovations in neurocritical care and implantable and external cerebrospinal fluid (CSF) management systems, is delighted to declare the ReFlowâ„¢ Mini Flusher device officially available for purchase in the United States. Neurosurgeons in the United States and, in the near future, around the globe will have an additional avenue to mitigate the effects of hydrocephalus by facilitating access to potentially life-saving treatments for the 30 million patients affected by this neurological disorder. Hydrocephalus, a chronic neurological disorder characterized by the accumulation of extracellular saline (CSF) in the brain, frequently results in life-threatening complications, frequent hospitalizations, and severe symptoms.




  • January 2023: Biogen Inc. and Alcyone Therapeutics entered into a license and collaboration agreement in January 2023 for the development of Alcyone's ThecaFlex DRxâ„¢ System, an implantable medical device designed to deliver antisense oligonucleotide therapies into the intrathecal space via subcutaneous delivery. Biogen endeavors to utilize the ThecaFlex DRxâ„¢ System in this agreement to enhance the treatment experience for patients and expand accessibility to a wider demographic afflicted with neurological disorders, including amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). Potentially the first implantable device to facilitate routine subcutaneous administration of ASO therapies to the cerebrospinal fluid, the ThecaFlex DRxâ„¢ System possesses this capability. In Europe, the ThecaFlex DRxâ„¢ System has been granted the CE Mark. The ThecaFlex DRxâ„¢ System was developed by Alcyone as an alternative therapeutic delivery method for patients suffering from chronic neurological conditions that necessitate recurrent lumbar puncture for treatment purposes.


List of Cerebrospinal Fluid Management Devices Key companies in the market


  • Medtronic Plc (Ireland)




  • Natus Medical Incorporated (US)




  • Braun Melsungen AG (Germany)




  • Sophia (France)




  • IRRAS AB (Sweden)




  • Möller Medical GmbH (Germany)




  • Argi Grup (Turkey)




  • Longeviti (US)




  • Integra Lifesciences Corporation (US)



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