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Central Pontine Myelinolysis Market Size

ID: MRFR//3161-HCR | 80 Pages | Author: Rahul Gotadki| November 2024

Central Pontine Myelinolysis (CPM) refers to a rare neurological disorder whereby nerve cells in the middle of the brainstem lose their fatty covering. There are several market dynamics for CPM treatments that make its market quite niche. The incidence of risk factors such as rapid correction of hyponatremia, alcoholism, liver transplantation and malnutrition is an important factor in determining demand for effective treatment for CPM.

The research and development efforts of pharmaceutical industry also determine the Central Pontine Myelinolysis market. Limited understanding and lack of specific targeted therapies on CPM present opportunities for novel drug development. Companies researching into mechanisms underlying CPM and developing more efficient and targeted cures are likely to have competitive advantage in this emerging market. Collaborations between firms in this sector with health care organizations and research institutions are vital if any progress is to be made in CPM related research towards new cures.

Another key driver in the market is the regulatory environment governing approval and commercialization of CPM treatments. Given how rare it is, it may be possible for regulatory agencies to expedite drug approval processes, thus offering opportunities for quickened availability of medicines by pharmaceutical companies. Nevertheless, very strict regulations ensure safety and efficacy of these interventions making compliance vital for players operating within this industry.

Healthcare infrastructure along with reimbursement landscape are other factors that affect Central Pontine Myelinolysis market. Patient outcomes as well as subsequent growth could be influenced by diagnostic tools available and used during early detection stages as well as available treatment options among others. Moreover, positive reimbursement policies can motivate healthcare providers to focalize their objectives on treating patients suffering from Central Pontine Myelinolysis thereby creating conducive grounds that promote business expansion across boarders around the globe. Knowledge among medical practitioners about CPN through training programs together with adopting practice guidelines are critical elements to develop a good quality health care system necessary for supporting the market’s development.

Another determinant of the Central Pontine Myelinolysis market is changing patterns of patient awareness and advocacy. With increased knowledge about CPM among patients, carers, and the public in general, there will be a greater demand for early diagnosis and effective treatments. Support groups also play an important role in increasing public awareness of CPM by influencing healthcare policies through their campaigns. This shift towards becoming more patient-centric could change the market dynamics with focus on treatments that can be made available to them easily without having to go through many struggles.

Healthcare spending and research and development funding are examples of economic factors affecting the Central Pontine Myelinolysis market. Government, nonprofit organizations, as well as private investors finance initiatives aimed at pushing forward CPM research and treatment developments. / The pace of progress in this field can be significantly affected by such factors as economic stability or resource allocation within healthcare sector.”

Covered Aspects:

Report Attribute/Metric Details
Growth Rate   7.9%

Global Central Pontine Myelinolysis Market Overview


The Central Pontine Myelinolysis Market Size was valued at USD 2.94 Billion in 2023. The Global Central Pontine Myelinolysis industry is projected to grow from USD 3.19 Billion in 2024 to USD 6.03 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 9.21% during the forecast period (2024 - 2032). Central Pontine Myelinolysis (CPM), also known as osmotic demyelination syndrome or central pontine demyelination, is a neurological disorder caused by severe damage of the myelin sheath of neurons.

CPM mostly affects the pons area of the brain and is characterized by acute paralysis, difficulty swallowing (dysphagia), difficulty speaking (dysarthria), and other neurological symptoms. These neurological symptoms are manifested into nausea and vomiting, disturbed consciousness, gait changes, confusion, headache, seizures etc. Serious progressive neurological symptoms are the progressive development of spastic tetraparesis, pseudobulbar palsy etc.

The causes of CPM are, rapid correction of low blood sodium levels (hyponatremia) affected by severe liver disease, liver transplant, alcoholism, severe burns, malnutrition, anorexia, severe electrolyte disorders, AIDS, hyperemesis gravidarum, anorexia nervosa, hematopoietic stem cell transplantation, Wernicke encephalopathy etc. The market drivers for central pontine myelinolysis market are increase in the risk factors such as hyponatremia cases, increasing screening and penetration of healthcare, growing income and healthcare expenditure etc. The market restraints are poor cure rates of central pontine myelinolysis, treatment, high cost of treatment etc.

Intended Audience


  • Global central pontine myelinolysis treatment manufacturers & suppliers

  • Research and development (R&D) companies

  • Hospitals and clinics

  • Academic institutes and universities


Figure 1 Global Central Pontine Myelinolysis Market by Diagnosis, 2016 (% market share) Global Central Pontine Myelinolysis Market

Global Central Pontine Myelinolysis Market Segmentation


The global central pontine myelinolysis market has been segmented on the basis of diagnosis, treatment, and end users.


Based on diagnosis, the market has been segmented as magnetic resonance imaging (MRI), computerized tomography (CT), electroencephalography and others.


Based on treatment, the market has been segmented as vitamin supplementation, electrolyte mainainence and others.


Based on the end users, the market has been segmented as hospitals & clinics, academic and research and others.


Global Central Pontine Myelinolysis Market Regional Analysis


The Americas account for a significant market share owing to extensive use of medications and high expenditure on the health care driven by the increasing incidence of related diseases and clinical conditions that can cause CPM. Additionally, the fastest uptake of new drugs in the US drives the central pontine myelinolysis market. Also, concentration of major research companies and hospitals in the developed countries of this region is adding fuel to the market growth. The large expenditure on the US healthcare, accounting to 16% of GDP, also cruises the sale of central pontine myelinolysis treatment.


Europe is the second largest market in the world due to high income and healthcare penetration. Europe is led by nations such as Germany and France. UK is expected to be the fastest growing market.


Asia Pacific region is expected to grow rapidly and China and India are likely to lead this market due to fast growing healthcare sector during the forecast period.


Gulf nations such as Saudi Arabia and the UAE are estimated to drive the Middle East & African market. The African region is expected to witness a moderate growth owing to poor economic and political conditions and poor healthcare development.


Key Players in the Global Central Pontine Myelinolysis Market


Some of key players profiled in the report are: 



  • Fujifilm Holdings Corporation

  • GE Healthcare

  • Siemens Healthcare GmbH

  • Philips Healthcare (Koninklijke Philips N.V.)

  • Shimadzu Corporation

  • Toshiba Medical Systems Corporation

  • Carestream Health 

  • Hitachi Medical Corporation


The report for Global Central Pontine Myelinolysis market by Market Research Future comprises of extensive primary research along with the detailed analysis of qualitative as well as quantitative aspects by various industry experts, key opinion leaders to gain a deeper insight of the market and industry performance. The report gives a clear picture of the current market scenario which includes past and estimated future market size with respect to value and volume, technological advancement, macro economical and governing factors in the market. The report provides detail information about and strategies used by top key players in the industry. The report also gives a broad study of the different market segments and regions.

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