Pouchitis is a kind of inflammation that happens in the ileal pouch reservoir. This condition is not specific and typically occurs in individuals who already have ulcerative colitis (UC). It is quite rare in people with Familial adenomatous polyposis (FAP). Those who have UC or FAP may choose to undergo a surgery called ileal pouch-anal anastomosis (IPAA) as a treatment, and pouchitis can sometimes occur after this surgery. Doctors usually recommend a procedure called pouch endoscopy to diagnose this condition. This procedure provides important information about the severity of mucosal inflammation, Crohn's disease (CD) of the pouch or cuffitis, the presence or absence of concurrent backwash ileitis, and the presence or absence of structural abnormalities.
The growth of the pouchitis market is being driven by several factors. Firstly, there is an increasing prevalence of ulcerative colitis, a need for Ileal Pouch–Anal Anastomosis procedures, prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), and a growing elderly population. The global incidence of ulcerative colitis, leading to pouchitis, is on the rise, especially among the aging population. A study published in the World Journal of Gastroenterology in 2015 suggests that the underlying causes of ulcerative colitis may significantly contribute to the development of pouchitis.
However, despite these positive factors, there are certain challenges that could impact the growth of the market. The available treatment options for pouchitis may have side effects, and there are strict regulations from the Food and Drug Administration (FDA) that need to be adhered to. These challenges might pose obstacles to the market's expansion.
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