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Alpha 1 Antitrypsin Deficiency Treatment Market Size

ID: MRFR//6847-HCR | 111 Pages | Author: Kinjoll Dey| November 2024

The market for Alpha-1 Antitrypsin Deficiency (AATD) treatment is affected by its prevalence and public and medical awareness. Awareness may increase the number of people diagnosed, increasing the demand for treatment options.
The AATD treatment business depends on diagnostic technology availability and advancement. Enhanced diagnostic tools provide rapid and accurate fault diagnosis, increasing the requirement for suitable treatment.
Continuous AATD treatment research and development affects market dynamics. Pharmaceutical research, genetic treatments, and other treatment approaches may provide new possibilities and change business competition.
Government health agencies regulate AATD treatment markets. Approval, reimbursement, and regulatory compliance affect innovative pharmaceutical availability and adoption, shaping the market environment.
Innovative and effective AATD therapies drive market growth. New treatments with greater efficacy, safety, and patient outcomes may swiftly gain market acceptance and influence treatment options.
Alpha-1 Antitrypsin Deficiency (AATD) patients' age, gender, and area impact market volatility. Understanding patient requirements helps pharmaceutical firms sell to diverse patient populations.
AATD medicines' availability and accessibility depend on healthcare infrastructure. Strong healthcare systems may improve diagnosis, treatment, and management, expanding the market.
Pharmaceutical and biotechnology companies affect market competition. Market share, price, and generic alternatives affect Alpha-1 Antitrypsin Deficiency therapy.
Patient advocacy groups matter. These groups raise awareness, influence government policy, and promote AATD research. Their activities may effect public perception and market function.
Economic conditions and healthcare spending vary by region affect AATD therapy price and availability. Economic downturns or changes may impair the availability of expensive therapies, which may alter market demand.
Pharma, research, and healthcare organizations create Alpha-1 Antitrypsin Deficiency (AATD) treatments together. Strategic partnerships may improve research, drug development, and market growth.
Clinical trial results strongly influence market sentiments. Positive results may increase investor trust, government endorsements, and market acceptability, while negative outcomes can have the reverse effect.

Covered Aspects:

Report Attribute/Metric Details
Growth Rate   13.23%

Alpha-1 Antitrypsin Deficiency Treatment Market Overview


Alpha-1 Antitrypsin Deficiency Treatment Market Size was valued at USD 3.12 Billion in 2023. The Global Alpha-1 Antitrypsin Deficiency Treatment industry is projected to grow from USD 3.52 Billion in 2024 to USD 9.28 Billion by 2032, exhibiting a compound annual growth rate (CAGR) of 13.23% during the forecast period (2024 - 2032).


Alpha-1 Antitrypsin Deficiency Treatment Market


Growing product pipeline for alpha-1 antitrypsin drugs and rising prevalence of alpha-1 antitrypsin deficiency are set to drive the market growth for alpha-1 antitrypsin deficiency treatment. Approximately 100,000 people in the US are known to suffer from alpha-1 antitrypsin deficiency. Rising awareness regarding the alpha-1 antitrypsin deficiency is expected to drive the market growth of the alpha-1 antitrypsin deficiency treatment.


Strategic mergers & acquisitions are also projected to boost alpha-1 antitrypsin deficiency treatment market growth with companies looking to strengthen their market positions, expand their product portfolios, and improve their brand images. For instance, on 3rd September 2019, Kamada Pharmaceuticals signed an agreement with Takeda Pharmaceutical Ltd for supply and distribution of Glassia, which is an alpha-1 proteinase inhibitor used for the treatment of alpha-1 antitrypsin deficiency.


High unmet medical needs in developing economies are directly providing lucrative opportunities for the alpha-1 antitrypsin deficiency treatment market growth.


Market Influencers


The rising number of product approvals. For instance, in September 2017, Grifols S.A. received a biologics license approval for Alpha-1 Proteinase Inhibitor to add a new liquid formulation to the currently licensed Prolastin C.


Market Drivers



  • Increasing prevalence of alpha-1 antitrypsin deficiency. Alpha-1 antitrypsin deficiency or AATD is a genetic disease that may cause severe lung or liver disfunction. The prevalence of alpha-1 antitrypsin deficiency is increasing, which is resulting in market growth. 1 in 1500 to 3500 Europeans are affected by AATD. Since the prevalence of AATD is increasing, the demand for treatment of AATD is also increasing, which is resulting in the positive market growth of the alpha-1 antitrypsin deficiency treatment.

  • Growing product pipeline for alpha-1 antitrypsin deficiency treatment drugs

  • Rising awareness regarding alpha-1 antitrypsin deficiency

  • High unmet medical needs in developing economies

  • Increasing R&D expenditure by key players to develop innovative treatment options for AATD


Market Restraints



  • Stringent government regulatory policies

  • High cost of drugs


Alpha-1 Antitrypsin Deficiency Treatment Market Segmentation Insights


Alpha-1 Antitrypsin Deficiency Treatment Drugs Insights



  • Alpha-1 Proteinase Inhibitor: This drug type is expected to hold the largest market share. In April 2019, CSL Behring received FDA approval for Zemaira, which is alpha-1 proteinase inhibitor. So, the rising number of product approvals is expected to drive the alpha-1 antitrypsin deficiency treatment market growth.

  • Bronchodilators: Used for prevention from upper respiratory tract infections.

  • Steroids: Consists of corticosteroids used for the treatment of COPD associated with AATD.

  • Others: Consists of oxygen therapy, antibiotics, and other drugs used for the treatment of complications associated with AATD, such as jaundiced skin, breathing problems, etc.


Alpha-1 Antitrypsin Deficiency Treatment Route of Administration Insights



  • Oral: This route of administration is expected to hold the largest alpha-1 antitrypsin deficiency treatment market share due to its high usage.

  • Intravenous: This drug type is expected to grow at the fastest rate owing to the ease of administration.

  • Inhalation: This route of administration is mainly used for administration of corticosteroids and drugs for the treatment of breathing disorders associated with AATD.

  • Others: Consists of subcutaneous and intramuscular routes of administration.


Alpha-1 Antitrypsin Deficiency Treatment Distribution Channel Insights



  • Hospital Pharmacy: The segment holds the largest market size as the treatment is mostly carried out in hospitals.

  • Retail Pharmacy: They provide prescriptions that are intended to be used at home.

  • Online Stores: Fastest growing segment owing to the increasing number of online pharmacy stores.


Alpha-1 Antitrypsin Deficiency Treatment Regional Insights



  • Americas: The largest regional market. The high patient population suffering from alpha-1 antitrypsin deficiency is expected to drive the market growth of alpha-1 antitrypsin deficiency treatment. Approximately 1 in 2,500 Americans suffer from the disease. This serves to drive the market growth of the alpha-1 antitrypsin deficiency treatment in the region.

  • Europe: Europe has some of the best healthcare services in the world. Increasing prevalence and the developed healthcare industry are driving the alpha-1 antitrypsin deficiency treatment market growth.

  • Asia-Pacific: The fastest-growing regional market for alpha-1 antitrypsin deficiency treatment, Asia-Pacific has the world’s largest population and fast-developing healthcare industry which is anticipated to drive the market growth.

  • Middle East & Africa: The market growth of alpha-1 antitrypsin deficiency treatment is attributed to the developing healthcare industry in regions such as Saudi Arabia, Oman, and Qatar.


Key Players



  • Kamada Pharmaceuticals (Israel)

  • CSL Behring LLC (US)

  • Grifols, S.A. (Spain)

  • Takeda Pharmaceutical Company Limited (Japan)

  • GlaxoSmithKline plc (UK)

  • Boehringer Ingelheim GmbH (Germany)

  • AstraZeneca (UK)

  • Vectura Group plc (UK)

  • Pfizer Inc. (US)

  • Mylan Inc. (US)


 

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