Epidemiology Study - Overview

Opioid use disorder (OUD)Study Objective:

To determine the prevalence and incidence of Opioid use disorder among individuals in a defined population. This objective outlines the primary aim of the study, which is to establish the frequency of Opioid use disorder within a specific age group and geographic area, while also seeking to understand potential factors contributing to its development. Moreover, the report is having geographic coverage including North America, Europe and rest of the world however customisation can be made in the geographic coverage.

Opioid use disorder (OUD) Study USP:

• This epidemiological study on Opioid use disorder stands out due to its comprehensive approach in establishing precise prevalence rates, identifying novel risk factors, and exploring geographical variations in a diverse population.

• By integrating advanced imaging techniques with robust statistical analyses, the study aims to provide actionable insights to identify treatment opportunities, target population, and an overview on public health initiatives aimed at mitigating the impact of Opioid use disorder related health problems.

• Through meticulous data collection and rigorous methodology, the study not only contributes to the scientific understanding of Opioid use disorder but also serves as a foundation for future research events and healthcare policymaking in addressing this increasing Opioid use disorder cases.

Opioid use disorder (OUD) related Study Overview:

The study Defines Opioid use disorder as an advanced form of disease. The significance of studying Opioid use disorder epidemiology is due to its increasing prevalence in different age populations.

Opioid use disorder (OUD) Study Design:

Population: The target population and the sampling method (e.g., random sampling from healthcare registries or population databases)

Data Collection: Detail methods for identifying Opioid use disorder cases (e.g., clinical examination,) and demographic data (age, sex, ethnicity).

Opioid use disorder (OUD) Epidemiological Parameters:

Prevalence: Prevalence rates considered per 1,000 or 10,000 population.

Incidence: Determine annual incidence rates per 1,000 person-years.

Risk Factors: Analyze associations between Opioid use disorder (OUD) and potential risk factors (e.g., age).

Geographical Variations: Compare prevalence or incidence rates across different regions or countries.

Opioid use disorder (OUD) study summary:

Opioid use disorder study summarizes the prevalence, incidence, possible risk factors, and geographic variations of the Obesity worldwide.

Opioid use disorder (OUD)Disease overview:

The national library of medicine has defined opioid use disorder as a chronic use of opioids, which can cause stress and cognitive impairment. It is addiction of opioid, medical condition which make patient to make compulsive use of opioid, even bearing with its negative effects. Symptoms include over desire for using opioids, tolerance levels increased for opioids and when use is discontinued symptoms of withdrawal syndrome are seen, weight loss, constricted pupils, intense cravings, negligence towards responsibilities.

opioid use disorder and opioid addiction has some of the main types, which includes, heroin addiction, oxycodone addiction, morphine addiction, codeine addiction, fentanyl addiction, methadone addiction, oxymorphone addiction, and tramadol addiction.

According to WHO, it is estimated that about 125,000 individuals died due to opioid overdose across the world in 2019. Moreover, in year 2020 to 2021, death rates due to opioid over use increased by 15% in US, it has become challenging global health crisis. Recreational use of opioids was highest in 2010 and decreased due to increased gained attention on opioid epidemic in US. 16 million people globally and 3 million in US fall in OUD criteria. Opioids have killed many people in US than any other drug in the history.

Treatment of Opioid Use Disorder involves the use of therapeutics, which includes Buprenorphine, Naltrexone, and Methadone. key market players manufacturing therapeutics for the treatment of OUD are as follows; Alkermes, Inc., Indivior PLC, BioDelivery Sciences International, Inc., Orexo US, Inc., Titan Pharmaceuticals, Inc., Omeros Corporation, Camurus, Hikma Pharmaceuticals PLC, AstraZeneca plc, Viatris Inc.

State Opioid Response (SOR) grants and Tribal Opioid Response (TOR) grants are the opioid response grants programs, helping to address opioid related crisis by providing fund, prevention, reduction, treatment and recovery support services. Grants of SOR available for states like D.C., and U.S. territories and TOC grants are permitted to federally recognized Tribes and tribal organizations. Since the fiscal year 2018, nationwide, Substance Abuse and Mental Health Services Administration (SAMHSA) had given$8.1 billion in SOR grants $307.5 million in TOR grants. They give funding depending on factors like overdose death rates and they have recently revised its allocation to better ensure funding goes to recipients with the greatest need.

Opioid use disorder (OUD)Demographic and Environmental Risk Factors:

Age and sex: Men are more into use of opioids; therefore, men show more cases of opioid related overdoses and health issues. Death rates due to opioid use disorder globally were 43,447, 14,502,031 prevalent cases and 2,396,734 new cases, are documented in adolescent young adults among different age groups, lower rates of incidence observed in adolescent young adults aged 25 to 39 years, and showed higher prevalence, mortality rates as compared to 15 to 24 years age group people. Males show increased Age specific mortality rates in year 2016 to 2019 while females showed no change in mortality rates during the same period, female rate of incidence increased sharply after 2014.

Ethnicity: Opioid related mortality rate was almost same in all racial/ethnic groups till 1999, it has raised sharply in non-Hispanic white individuals and rate of opioid overdose fatality has increased twice for both black and Hispanic individuals by 2014. Total opioid overdose rate and prescription opioid specific and heroin specific death rates are seen to be highest in non-Hispanic whites as compared to other ethnic groups. Some other studies compare non-Hispanic white, black and Hispanic individual, for instance, according to 2024 to 2013 study of National Survey on Drug Use and Health (NSDUH) data, prescription opioid misuse is highest in white adolescents as compared to black and Hispanic adolescents.

Risk Factors causing Opioid use disorder (OUD): Factors which can cause opioid use disorder includes, past/ current substance abuse, psychiatric disorders, people living with chronic pain, young age, childhood trauma starting opioid use in early age, certain environmental factors playing role in making person overdose opioids and cause the disorder are, peer pressure, poverty, unemployment, housing instability, absence of supportive relationship, growing in culture supportive to opioid use, social and family environment.

Opioid use disorder (OUD) Market Scope:

Drivers: In the Opioid Use Disorder (OUD) market, a prominent trend involves the increasing integration of telehealth services to enhance accessibility to treatment. Telehealth solutions provide a convenient and confidential platform for individuals struggling with OUD to access counselling, therapy, and medication-assisted treatment remotely. This trend not only addresses barriers related to stigma and geographic constraints but also supports ongoing care, contributing to more comprehensive and patient-centric approaches to managing opioid dependence. This factor drives the Market CAGR.

Additionally, the OUD market is witnessing significant advancements in Medication-Assisted Treatment (MAT), with the development of new medications and improved formulations. MAT combines pharmaceutical interventions with counselling and behavioural therapies to address opioid addiction comprehensively. Emerging medications, such as extended-release formulations or novel combination therapies, aim to enhance treatment efficacy, reduce withdrawal symptoms, and improve patient adherence. These innovations signify a commitment to refining therapeutic options and aligning with the evolving needs of individuals seeking effective and evidence-based interventions for Opioid Use Disorder.

A crucial trend in the Opioid Use Disorder market involves a heightened emphasis on harm reduction strategies. Recognizing the complex nature of addiction, there is a growing shift towards harm reduction initiatives that prioritize minimizing the negative consequences of Opioid Use rather than solely focusing on abstinence. This trend encompasses the widespread distribution of naloxone, supervised consumption sites, and needle exchange programs, aiming to prevent opioid overdoses and reduce the associated health risks. The focus on harm reduction reflects a more compassionate and pragmatic approach to addressing the multifaceted challenges posed by Opioid Use Disorder. For instance, in June 2022, Titan Pharmaceuticals, Inc. entered into a partnership with Indegene to establish a multichannel digital marketing program throughout the U.S. and further increase their competence in providing Probuphine implants to opioid addiction patients. Thus, driving the Opioid Use Disorder market revenue.

Restraints: Some of the adverse side effects caused due to administration of the drugs for treating opioid use disorder or opioid addiction are seen to be hampering the global market growth for drugs of opioid use disorder. Even lack of awareness and limited product availability are key challenges which hampers the expansion of the market.